AU2003210345B2 - Ambroxol for treating painful conditions in the mouth and pharyngeal cavity - Google Patents

Ambroxol for treating painful conditions in the mouth and pharyngeal cavity Download PDF

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Publication number
AU2003210345B2
AU2003210345B2 AU2003210345A AU2003210345A AU2003210345B2 AU 2003210345 B2 AU2003210345 B2 AU 2003210345B2 AU 2003210345 A AU2003210345 A AU 2003210345A AU 2003210345 A AU2003210345 A AU 2003210345A AU 2003210345 B2 AU2003210345 B2 AU 2003210345B2
Authority
AU
Australia
Prior art keywords
ambroxol
oral
composition
pain
pharyngeal cavity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2003210345A
Other languages
English (en)
Other versions
AU2003210345A1 (en
Inventor
Anke Esperester
Uwe Pschorn
Jean-Michel Vix
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Boehringer Ingelheim Pharma GmbH and Co KG
Boehringer Ingelheim Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27740434&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2003210345(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Pharma GmbH and Co KG, Boehringer Ingelheim Pharmaceuticals Inc filed Critical Boehringer Ingelheim Pharma GmbH and Co KG
Publication of AU2003210345A1 publication Critical patent/AU2003210345A1/en
Application granted granted Critical
Publication of AU2003210345B2 publication Critical patent/AU2003210345B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Otolaryngology (AREA)
  • Communicable Diseases (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2003210345A 2002-02-27 2003-02-25 Ambroxol for treating painful conditions in the mouth and pharyngeal cavity Ceased AU2003210345B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10208313.4 2002-02-27
DE10208313A DE10208313A1 (de) 2002-02-27 2002-02-27 Ambroxol für die Behandlung von schmerzhaften Zuständen im Mund und Rachenraum
PCT/EP2003/001886 WO2003072094A1 (de) 2002-02-27 2003-02-25 Ambroxol für die behandlung von schmerzhaften zuständen im mund und rachenraum

Publications (2)

Publication Number Publication Date
AU2003210345A1 AU2003210345A1 (en) 2003-09-09
AU2003210345B2 true AU2003210345B2 (en) 2009-01-29

Family

ID=27740434

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003210345A Ceased AU2003210345B2 (en) 2002-02-27 2003-02-25 Ambroxol for treating painful conditions in the mouth and pharyngeal cavity

Country Status (21)

Country Link
EP (1) EP1480626A1 (enExample)
JP (1) JP2005518435A (enExample)
KR (1) KR20040084944A (enExample)
CN (1) CN1638749A (enExample)
AR (1) AR038698A1 (enExample)
AU (1) AU2003210345B2 (enExample)
BR (1) BR0308038A (enExample)
CA (1) CA2477105A1 (enExample)
DE (1) DE10208313A1 (enExample)
EC (1) ECSP045242A (enExample)
IS (1) IS7417A (enExample)
MX (1) MXPA04008220A (enExample)
MY (1) MY144781A (enExample)
PE (1) PE20030830A1 (enExample)
PL (1) PL371584A1 (enExample)
RU (1) RU2311176C2 (enExample)
TW (1) TW200306804A (enExample)
UA (1) UA86741C2 (enExample)
UY (1) UY27679A1 (enExample)
WO (1) WO2003072094A1 (enExample)
ZA (1) ZA200405635B (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10332486A1 (de) * 2003-07-16 2005-02-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Ambroxol für die Behandlung akuter Schmerzen
JP2005120063A (ja) * 2003-10-14 2005-05-12 Boehringer Ingelheim Pharma Gmbh & Co Kg 咽頭における炎症の治療のためのアンブロキソール
ITMI20032462A1 (it) * 2003-12-16 2005-06-17 Advance Holdings Ltd Metodo per preparare una caramella contenente ambroxolo e la caramella cosi' ottenuta
DE102004021992A1 (de) * 2004-05-03 2005-11-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg Topische Zubereitung enthaltend Ambroxol
JP2007084471A (ja) * 2005-09-21 2007-04-05 Sunstar Inc 口腔用組成物および口腔用製品の選択方法
EP2015761A4 (en) * 2006-03-29 2009-07-29 Naveh Pharma 1996 Ltd METHOD AND COMPOSITION FOR THE TREATMENT OF NUTRITIONAL IGNITION
JP5765934B2 (ja) * 2009-12-28 2015-08-19 サンスター株式会社 口腔用組成物
JP6171683B2 (ja) * 2012-08-03 2017-08-02 大正製薬株式会社 固形製剤
CN105769908B (zh) * 2016-05-06 2019-03-01 湖北凤凰白云山药业有限公司 一种化痰止咳的药物及其制备方法
CN109982692A (zh) 2016-11-14 2019-07-05 王明武 用于治疗眼表疾病的制剂和相关方法
CN106727621A (zh) * 2016-11-22 2017-05-31 郑州仁宏医药科技有限公司 一种治疗牙痛的西药散剂
JP6844394B2 (ja) * 2017-04-14 2021-03-17 大正製薬株式会社 固形組成物
EP3415143A1 (en) 2017-06-16 2018-12-19 Kai-Uwe Kern Bromhexine for the treatment of pain

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0896815A1 (en) * 1996-05-02 1999-02-17 Taisho Pharmaceutical Co. Ltd Suspension of sparingly water-soluble acidic drug

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3034975C2 (de) * 1980-09-17 1986-11-27 Dr. Karl Thomae Gmbh, 7950 Biberach Arzneimittelkombination zur Behandlung infektiöser Atemwegerkrankungen
EP0138020B1 (de) * 1983-09-17 1992-06-03 Dr. Karl Thomae GmbH Antiadhäsive Prophylactica und Arzneimittel enthaltend ein sekretolytisch wirksames Benzylaminderivat
DE3445226A1 (de) * 1983-12-14 1985-08-01 Reifenrath, Rainer Richard Otto, Dr.med., 7920 Heidenheim Pharmazeutisches erzeugnis zur behandlung und prophylaxe von infektionen sowie von husten und obstruktiven atemwegserkrankungen
US5122540A (en) * 1986-02-28 1992-06-16 W. Keith R. Watson Method and composition for treating warts and throat soreness with DMSO and citric acid
US5458879A (en) * 1994-03-03 1995-10-17 The Procter & Gamble Company Oral vehicle compositions
DE4415553A1 (de) * 1994-05-03 1995-11-09 Behringwerke Ag Verwendung von Deoxyspergualin zur Herstellung eines Arzneimittels zur Behandlung von entzündlich-hyperreaktiven Erkrankungen
DE19933148A1 (de) * 1999-07-20 2001-01-25 Boehringer Ingelheim Int Ambroxolhaltige Lutschtablette
JP2001151677A (ja) * 1999-11-26 2001-06-05 Taisho Pharmaceut Co Ltd 咽頭用組成物
RU2169557C1 (ru) * 1999-12-22 2001-06-27 Александр Афанасьевич Яремчук Сироп амброксола для лечения бронхопульмональных заболеваний
DE20102817U1 (de) * 2000-02-23 2001-06-07 Bolder Arzneimittel GmbH, 50968 Köln Lutsch- und Kaupastillen mit Cyclodextrin
US6391886B1 (en) * 2000-12-04 2002-05-21 The Procter & Gamble Company Oral compositions having improved consumer aesthetics

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0896815A1 (en) * 1996-05-02 1999-02-17 Taisho Pharmaceutical Co. Ltd Suspension of sparingly water-soluble acidic drug

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Weiser T W, Society for Neuroscience Abstracts, vol 26, No 1-2, 2000,page "abstract No.454.14". *

Also Published As

Publication number Publication date
KR20040084944A (ko) 2004-10-06
RU2311176C2 (ru) 2007-11-27
MXPA04008220A (es) 2004-11-26
CA2477105A1 (en) 2003-09-04
PE20030830A1 (es) 2003-10-31
EP1480626A1 (de) 2004-12-01
TW200306804A (en) 2003-12-01
RU2004129284A (ru) 2005-06-10
JP2005518435A (ja) 2005-06-23
PL371584A1 (en) 2005-06-27
CN1638749A (zh) 2005-07-13
WO2003072094A1 (de) 2003-09-04
UA86741C2 (ru) 2009-05-25
UY27679A1 (es) 2003-09-30
AU2003210345A1 (en) 2003-09-09
AR038698A1 (es) 2005-01-26
DE10208313A1 (de) 2003-09-11
ECSP045242A (es) 2004-09-28
BR0308038A (pt) 2004-12-28
IS7417A (is) 2004-08-19
MY144781A (en) 2011-11-15
ZA200405635B (en) 2005-05-31

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired