AU2002313542B2 - N-phenylpyrrole guanidine derivatives as melanocortin reception ligands - Google Patents
N-phenylpyrrole guanidine derivatives as melanocortin reception ligands Download PDFInfo
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- AU2002313542B2 AU2002313542B2 AU2002313542A AU2002313542A AU2002313542B2 AU 2002313542 B2 AU2002313542 B2 AU 2002313542B2 AU 2002313542 A AU2002313542 A AU 2002313542A AU 2002313542 A AU2002313542 A AU 2002313542A AU 2002313542 B2 AU2002313542 B2 AU 2002313542B2
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- guanidine
- pyrrol
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- 239000003446 ligand Substances 0.000 title description 7
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- C07—ORGANIC CHEMISTRY
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- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
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Landscapes
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0119172.5A GB0119172D0 (en) | 2001-08-06 | 2001-08-06 | Phenyl pyrrole derivatives |
| GB0119172.5 | 2001-08-06 | ||
| PCT/GB2002/003620 WO2003013509A1 (en) | 2001-08-06 | 2002-08-06 | N-phenylpyrrole guanidine derivatives as melanocortin reception ligands |
Publications (2)
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| AU2002313542A1 AU2002313542A1 (en) | 2003-06-19 |
| AU2002313542B2 true AU2002313542B2 (en) | 2007-03-22 |
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| AU2002313542A Ceased AU2002313542B2 (en) | 2001-08-06 | 2002-08-06 | N-phenylpyrrole guanidine derivatives as melanocortin reception ligands |
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| GB0019357D0 (en) * | 2000-08-07 | 2000-09-27 | Melacure Therapeutics Ab | Novel phenyl guanidines |
| US7456184B2 (en) | 2003-05-01 | 2008-11-25 | Palatin Technologies Inc. | Melanocortin receptor-specific compounds |
| CA2462200A1 (en) | 2001-08-10 | 2003-02-20 | Palatin Technologies, Inc. | Peptidomimetics of biologically active metallopeptides |
| US7354923B2 (en) | 2001-08-10 | 2008-04-08 | Palatin Technologies, Inc. | Piperazine melanocortin-specific compounds |
| CA2473461C (en) | 2002-01-11 | 2011-11-01 | Sankyo Company, Limited | Amino alcohol derivative or phosphonic acid derivative and medicinal composition containing these |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| GB2398299A (en) * | 2003-02-13 | 2004-08-18 | Melacure Therapeutics Ab | Pharmaceutically active phenyl-pyrrole derivatives |
| RU2332212C2 (ru) | 2004-02-24 | 2008-08-27 | Санкио Компани, Лимитед | Аминоспирт |
| EP2305352A1 (en) | 2004-04-02 | 2011-04-06 | Merck Sharp & Dohme Corp. | 5-alpha-reductase inhibitors for use in the treatment of men with metabolic and anthropometric disorders |
| ES2571253T3 (es) * | 2006-06-09 | 2016-05-24 | Synact Pharma Aps | Derivados de fenil pirrol aminoguanidina |
| DK2170930T3 (da) | 2007-06-04 | 2012-11-05 | Synergy Pharmaceuticals Inc | Agonister af guanylatcyclase, anvendelige til behandlingen af gastrointestinale sygdomme, inflammation, cancer og andre sygdomme |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| ES2601856T3 (es) | 2007-06-08 | 2017-02-16 | Mannkind Corporation | Inhibidores de la IRE-1A |
| EP2045250A1 (en) * | 2007-09-26 | 2009-04-08 | Action Pharma A/S | Ring-substituted phenyl pyrrole aminoguanidine derivatives |
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| EP2328910B1 (en) | 2008-06-04 | 2014-08-06 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| ES2624828T3 (es) | 2008-07-16 | 2017-07-17 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros |
| JP2012500219A (ja) | 2008-08-15 | 2012-01-05 | エヌサーティー・ファーマシューティカルズ，エルエルシー | 治療薬剤としての、ｓ−ニトロソグルタチオンレダクターゼの新規ピロール阻害剤 |
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| DK2318007T3 (da) | 2008-08-15 | 2013-03-25 | N30 Pharmaceuticals Inc | Nye pyrrol-inhibitorer af s-nitrosoglutathion-reduktase som terapeutiske midler |
| US8410284B2 (en) | 2008-10-22 | 2013-04-02 | Merck Sharp & Dohme Corp | Cyclic benzimidazole derivatives useful as anti-diabetic agents |
| EP2362731B1 (en) | 2008-10-31 | 2016-04-06 | Merck Sharp & Dohme Corp. | Novel cyclic benzimidazole derivatives useful anti-diabetic agents |
| WO2010056717A1 (en) | 2008-11-17 | 2010-05-20 | Merck Sharp & Dohme Corp. | Substituted bicyclic amines for the treatment of diabetes |
| WO2011011508A1 (en) | 2009-07-23 | 2011-01-27 | Schering Corporation | Benzo-fused oxazepine compounds as stearoyl-coenzyme a delta-9 desaturase inhibitors |
| WO2011011506A1 (en) | 2009-07-23 | 2011-01-27 | Schering Corporation | Spirocyclic oxazepine compounds as stearoyl-coenzyme a delta-9 desaturase inhibitors |
| EP2298541A1 (en) | 2009-09-17 | 2011-03-23 | Rieter Technologies AG | Moulded automotive part |
| JP5990101B2 (ja) | 2009-09-16 | 2016-09-07 | オートニアム マネジメント アクチエンゲゼルシャフトＡｕｔｏｎｅｕｍ Ｍａｎａｇｅｍｅｎｔ ＡＧ | 自動車パネル用成型製品 |
| JP2013520502A (ja) | 2010-02-25 | 2013-06-06 | メルク・シャープ・エンド・ドーム・コーポレイション | 有用な抗糖尿病薬である新規な環状ベンズイミダゾール誘導体 |
| US8785634B2 (en) | 2010-04-26 | 2014-07-22 | Merck Sharp & Dohme Corp | Spiropiperidine prolylcarboxypeptidase inhibitors |
| US9365539B2 (en) | 2010-05-11 | 2016-06-14 | Merck Sharp & Dohme Corp. | Prolylcarboxypeptidase inhibitors |
| WO2011156246A1 (en) | 2010-06-11 | 2011-12-15 | Merck Sharp & Dohme Corp. | Novel prolylcarboxypeptidase inhibitors |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| SG192941A1 (en) | 2011-02-25 | 2013-09-30 | Merck Sharp & Dohme | Novel cyclic azabenzimidazole derivatives useful as anti-diabetic agents |
| EP2502788B1 (en) | 2011-03-23 | 2014-03-12 | Autoneum Management AG | Production process for a moulded multilayer lining |
| EP2503040A1 (en) | 2011-03-23 | 2012-09-26 | Autoneum Management AG | Moulded multilayer lining |
| EP2602248A1 (en) | 2011-12-05 | 2013-06-12 | University Of Leicester | Novel pyrrole compounds |
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| SE9604348D0 (sv) | 1996-11-26 | 1996-11-26 | Wapharm Ab | Användning av hydroxyguanidiner |
| US6127381A (en) * | 1998-04-28 | 2000-10-03 | Basu; Amaresh | Isoquinoline compound melanocortin receptor ligands and methods of using same |
| WO2001025192A1 (en) * | 1999-10-06 | 2001-04-12 | Melacure Therapeutics Ab | Guanidine derivatives and their use in the production of a medicament for blocking xanthine oxidase/dehydrogenase |
| GB0002059D0 (en) | 2000-01-28 | 2000-03-22 | Melacure Therapeutics Ab | Novel aromatic amines |
| GB0019357D0 (en) | 2000-08-07 | 2000-09-27 | Melacure Therapeutics Ab | Novel phenyl guanidines |
| GB0019359D0 (en) * | 2000-08-07 | 2000-09-27 | Melacure Therapeutics Ab | Novel guanidines |
| GB0108631D0 (en) * | 2001-04-05 | 2001-05-30 | Melacure Therapeutics Ab | Novel benzylideneamino guanidines and their uses as ligands to the melanocortin receptors |
| US6951881B2 (en) * | 2002-05-10 | 2005-10-04 | Wyeth | (1-substituted-indol-3-yl) alkylidenehydrazinecarboximidamide derivatives as 5-hydroxytryptamine-6 ligands |
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2001
- 2001-08-06 GB GBGB0119172.5A patent/GB0119172D0/en not_active Ceased
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2002
- 2002-08-06 NZ NZ529666A patent/NZ529666A/en not_active IP Right Cessation
- 2002-08-06 JP JP2003518518A patent/JP4450620B2/ja not_active Expired - Fee Related
- 2002-08-06 AU AU2002313542A patent/AU2002313542B2/en not_active Ceased
- 2002-08-06 EP EP02753136A patent/EP1414440B1/en not_active Expired - Lifetime
- 2002-08-06 BR BR0210445-8A patent/BR0210445A/pt not_active IP Right Cessation
- 2002-08-06 PT PT02753136T patent/PT1414440E/pt unknown
- 2002-08-06 WO PCT/GB2002/003620 patent/WO2003013509A1/en not_active Ceased
- 2002-08-06 US US10/484,444 patent/US7186748B2/en not_active Expired - Fee Related
- 2002-08-06 ES ES02753136T patent/ES2280555T3/es not_active Expired - Lifetime
- 2002-08-06 KR KR10-2003-7016099A patent/KR20040019302A/ko not_active Withdrawn
- 2002-08-06 DK DK02753136T patent/DK1414440T3/da active
- 2002-08-06 SI SI200230506T patent/SI1414440T1/sl unknown
- 2002-08-06 IL IL16018102A patent/IL160181A0/xx unknown
- 2002-08-06 MX MXPA04001037A patent/MXPA04001037A/es unknown
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- 2002-08-06 DE DE60217503T patent/DE60217503T2/de not_active Expired - Lifetime
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2004
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2006
- 2006-03-15 US US11/374,956 patent/US7442807B2/en not_active Expired - Fee Related
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- 2007-03-30 CY CY20071100446T patent/CY1106424T1/el unknown
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- 2008-09-17 US US12/232,399 patent/US20090018183A1/en not_active Abandoned
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| IL160181A0 (en) | 2004-07-25 |
| DK1414440T3 (da) | 2007-05-21 |
| US20040254093A1 (en) | 2004-12-16 |
| ES2280555T3 (es) | 2007-09-16 |
| DE60217503D1 (de) | 2007-02-22 |
| US20090018183A1 (en) | 2009-01-15 |
| BR0210445A (pt) | 2004-08-17 |
| CA2448356A1 (en) | 2003-02-20 |
| SI1414440T1 (sl) | 2007-06-30 |
| GB0119172D0 (en) | 2001-09-26 |
| KR20040019302A (ko) | 2004-03-05 |
| PT1414440E (pt) | 2007-04-30 |
| JP2005504039A (ja) | 2005-02-10 |
| DE60217503T2 (de) | 2007-08-09 |
| US7186748B2 (en) | 2007-03-06 |
| WO2003013509A1 (en) | 2003-02-20 |
| EP1414440B1 (en) | 2007-01-10 |
| NO20040465L (no) | 2004-02-02 |
| CA2448356C (en) | 2010-04-20 |
| EP1414440A1 (en) | 2004-05-06 |
| US20060148798A1 (en) | 2006-07-06 |
| NZ529666A (en) | 2006-04-28 |
| JP2009242414A (ja) | 2009-10-22 |
| CY1106424T1 (el) | 2011-10-12 |
| MXPA04001037A (es) | 2004-06-03 |
| JP4450620B2 (ja) | 2010-04-14 |
| US7442807B2 (en) | 2008-10-28 |
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