AU2002303199B2 - Gastrokines and derived peptides including inhibitors - Google Patents

Gastrokines and derived peptides including inhibitors Download PDF

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Publication number
AU2002303199B2
AU2002303199B2 AU2002303199A AU2002303199A AU2002303199B2 AU 2002303199 B2 AU2002303199 B2 AU 2002303199B2 AU 2002303199 A AU2002303199 A AU 2002303199A AU 2002303199 A AU2002303199 A AU 2002303199A AU 2002303199 B2 AU2002303199 B2 AU 2002303199B2
Authority
AU
Australia
Prior art keywords
protein
peptide
sequence
amino acid
peptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2002303199A
Other languages
English (en)
Other versions
AU2002303199A1 (en
Inventor
Kan Agarwal
Terence E. Martin
C. Thomas Powell
F. Gary Toback
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Chicago
Original Assignee
University of Chicago
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25234151&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2002303199(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by University of Chicago filed Critical University of Chicago
Publication of AU2002303199A1 publication Critical patent/AU2002303199A1/en
Application granted granted Critical
Publication of AU2002303199B2 publication Critical patent/AU2002303199B2/en
Assigned to THE UNIVERSITY OF CHICAGO reassignment THE UNIVERSITY OF CHICAGO Alteration of Name(s) in Register under S187 Assignors: UNIVERSITY OF CHICAGO
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/07Animals genetically altered by homologous recombination
    • A01K2217/075Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2002303199A 2001-03-29 2002-03-29 Gastrokines and derived peptides including inhibitors Ceased AU2002303199B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/821,726 2001-03-29
US09/821,726 US6734289B2 (en) 2001-03-29 2001-03-29 Gastrokines and derived peptides including inhibitors
PCT/US2002/010148 WO2002092758A2 (en) 2001-03-29 2002-03-29 Gastrokines and derived peptides including inhibitors

Publications (2)

Publication Number Publication Date
AU2002303199A1 AU2002303199A1 (en) 2003-05-01
AU2002303199B2 true AU2002303199B2 (en) 2008-03-13

Family

ID=25234151

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2002303199A Ceased AU2002303199B2 (en) 2001-03-29 2002-03-29 Gastrokines and derived peptides including inhibitors
AU2002258663A Ceased AU2002258663B2 (en) 2001-03-29 2002-03-29 Control of growth and repair of gastro-intestinal tissues by gastrokines and inhibitors

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2002258663A Ceased AU2002258663B2 (en) 2001-03-29 2002-03-29 Control of growth and repair of gastro-intestinal tissues by gastrokines and inhibitors

Country Status (10)

Country Link
US (4) US6734289B2 (enExample)
EP (2) EP1415154B1 (enExample)
JP (3) JP4281947B2 (enExample)
AT (1) ATE446510T1 (enExample)
AU (2) AU2002303199B2 (enExample)
CA (2) CA2442635A1 (enExample)
DE (1) DE60234103D1 (enExample)
ES (1) ES2332882T3 (enExample)
MX (2) MXPA03008855A (enExample)
WO (2) WO2002092758A2 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6734289B2 (en) * 2001-03-29 2004-05-11 The University Of Chicago Gastrokines and derived peptides including inhibitors
US7629317B2 (en) 2001-03-29 2009-12-08 The University Of Chicago Control of growth and repair of gastro-intestinal tissues by gastrokines and inhibitors
DE102004047968A1 (de) * 2004-10-01 2006-04-06 B.R.A.H.M.S Ag Bestimmung von Gastrokine 1 (GKN1) als Biomarker für Entzündungen und Infektionen
AU2006244080C1 (en) * 2005-05-10 2012-02-02 The University Of Chicago Use of peptides derived from the growth factor AMP-18 for the treatment of mucositis
MX2007013982A (es) * 2005-05-10 2008-03-13 Univ Chicago Uso de peptidos derivados del factor de crecimiento amp-18 para el tratamiento de la mucositis.
US8017576B2 (en) * 2005-05-10 2011-09-13 The University Of Chicago Methods and compositions to treat mucositis
ES2474573T3 (es) 2006-01-04 2014-07-09 Baxter International Inc Medio de cultivo celular sin oligop�ptidos
EP2082674A1 (en) 2008-01-22 2009-07-29 Trelleborg Building Systems AB Waterproof sealing profile
EP2254464B1 (en) * 2008-02-18 2017-01-04 Medimetrics Personalized Drug Delivery B.V. Administration of drugs to a patient
US9957316B2 (en) 2012-12-19 2018-05-01 Lumen Bio Llc Weight loss by inhibition of gastrokine
WO2018141969A1 (en) * 2017-02-06 2018-08-09 Biotempt B.V. Peptide modulators of the interaction between human c-peptide and human elastin receptor for therapeutic use
KR102590757B1 (ko) * 2020-12-11 2023-10-17 가톨릭대학교 산학협력단 GKN1(Gastrokine 1) 특이적 항체 및 이의 용도

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0972830A1 (en) * 1997-02-21 2000-01-19 Takara Shuzo Co, Ltd. Cancer-associated genes

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5476922A (en) 1987-06-24 1995-12-19 Arch Development Corporation Methods and compositions for the preparation and use of autocrine growth factors
US5135856A (en) 1987-06-24 1992-08-04 Arch Development Corp. Production of autocrine growth factors
US5102870A (en) 1989-04-14 1992-04-07 Schering Ag Treatment and prevention of oral mucositis with growth factors
JP2938129B2 (ja) 1989-05-02 1999-08-23 武田薬品工業株式会社 虚血性腎疾患の予防・治療剤
US5644026A (en) * 1994-05-03 1997-07-01 La Jolla Cancer Research Foundation Epitaxin, a cell motility factor
JPH08231413A (ja) 1994-12-29 1996-09-10 Mochida Pharmaceut Co Ltd 臓器障害に基づく疾患の予防・治療剤
JP3859710B2 (ja) 1995-04-21 2006-12-20 三菱化学株式会社 虚血性疾患の予防及び/又は治療剤
US20030083461A1 (en) * 1997-06-16 2003-05-01 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
AU8824098A (en) * 1997-08-06 1999-03-01 Genetics Institute Inc. Secreted proteins and polynucleotides encoding them
EP1090118A2 (en) 1998-06-26 2001-04-11 Incyte Pharmaceuticals, Inc. Human signal peptide-containing proteins
BR0008188A (pt) 1999-01-21 2002-02-13 Metamorphix Inc Inibidores de fator de diferenciação de crescimento e usos para os mesmos
CA2373915A1 (en) * 1999-06-02 2000-12-07 Genentech, Inc. Methods and compositions for inhibiting neoplastic cell growth
JP2004522402A (ja) * 1999-06-02 2004-07-29 ジェネンテック・インコーポレーテッド 同一のものをコードする分泌及び膜貫通ポリペプチドと核酸
US7629317B2 (en) 2001-03-29 2009-12-08 The University Of Chicago Control of growth and repair of gastro-intestinal tissues by gastrokines and inhibitors
US6734289B2 (en) * 2001-03-29 2004-05-11 The University Of Chicago Gastrokines and derived peptides including inhibitors
US8017576B2 (en) 2005-05-10 2011-09-13 The University Of Chicago Methods and compositions to treat mucositis

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0972830A1 (en) * 1997-02-21 2000-01-19 Takara Shuzo Co, Ltd. Cancer-associated genes

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Yoshikawa, Y. et al. (2000) Japanese Journal of Cancer Research. 91(5): 459 - 463 *

Also Published As

Publication number Publication date
CA2442684A1 (en) 2002-10-10
EP1423409A4 (en) 2005-12-07
WO2002092758A8 (en) 2003-02-20
CA2442635A1 (en) 2002-11-21
EP1415154A2 (en) 2004-05-06
JP4281947B2 (ja) 2009-06-17
AU2002258663B2 (en) 2008-02-21
US6734289B2 (en) 2004-05-11
ATE446510T1 (de) 2009-11-15
EP1423409A2 (en) 2004-06-02
EP1415154B1 (en) 2009-10-21
US7557083B2 (en) 2009-07-07
US8791068B2 (en) 2014-07-29
US20050054564A1 (en) 2005-03-10
US20050065328A1 (en) 2005-03-24
EP1415154A4 (en) 2004-12-22
WO2002078640A3 (en) 2004-03-04
ES2332882T3 (es) 2010-02-15
CA2442684C (en) 2013-11-19
JP2004532037A (ja) 2004-10-21
WO2002092758A3 (en) 2004-04-01
MXPA03008855A (es) 2004-12-06
JP4295516B2 (ja) 2009-07-15
US20130086701A1 (en) 2013-04-04
DE60234103D1 (de) 2009-12-03
JP2007217422A (ja) 2007-08-30
WO2002092758A2 (en) 2002-11-21
US8278269B2 (en) 2012-10-02
WO2002092758A9 (en) 2004-06-24
JP2004537284A (ja) 2004-12-16
WO2002078640A2 (en) 2002-10-10
MXPA03008861A (es) 2004-10-15
US20030017548A1 (en) 2003-01-23

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Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired