AU2002247059B2 - Method of treating inflammatory and immune diseases using inhibitors of IkappaB kinase (IKK) - Google Patents
Method of treating inflammatory and immune diseases using inhibitors of IkappaB kinase (IKK) Download PDFInfo
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- AU2002247059B2 AU2002247059B2 AU2002247059A AU2002247059A AU2002247059B2 AU 2002247059 B2 AU2002247059 B2 AU 2002247059B2 AU 2002247059 A AU2002247059 A AU 2002247059A AU 2002247059 A AU2002247059 A AU 2002247059A AU 2002247059 B2 AU2002247059 B2 AU 2002247059B2
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- ikk
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- disorder
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- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26585301P | 2001-02-01 | 2001-02-01 | |
| US60/265,853 | 2001-02-01 | ||
| US09/965,977 | 2001-09-27 | ||
| US09/965,977 US6960585B2 (en) | 2000-10-03 | 2001-09-27 | Amino-substituted tetracyclic compounds useful as anti-inflammatory agents and pharmaceutical compositions comprising same |
| PCT/US2002/003060 WO2002060386A2 (en) | 2001-02-01 | 2002-02-01 | METHODS OF TREATING INFLAMMATORY AND IMMUNE DISEASES USING INHIBITORS OF IλB KINASE (IKK) |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2007200555A Division AU2007200555A1 (en) | 2001-02-01 | 2007-02-08 | Methods of treating inflammatory and immune diseases using inhibitors of IKappaB kinase (IKK) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2002247059A1 AU2002247059A1 (en) | 2003-02-20 |
| AU2002247059B2 true AU2002247059B2 (en) | 2006-11-16 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2002247059A Ceased AU2002247059B2 (en) | 2001-02-01 | 2002-02-01 | Method of treating inflammatory and immune diseases using inhibitors of IkappaB kinase (IKK) |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1363993A4 (cs) |
| JP (1) | JP2004529088A (cs) |
| AU (1) | AU2002247059B2 (cs) |
| CA (1) | CA2436770A1 (cs) |
| CZ (1) | CZ20032287A3 (cs) |
| HU (1) | HUP0304045A3 (cs) |
| MX (1) | MXPA03006817A (cs) |
| NO (1) | NO20033429L (cs) |
| PL (1) | PL364111A1 (cs) |
| WO (1) | WO2002060386A2 (cs) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6960585B2 (en) * | 2000-10-03 | 2005-11-01 | Bristol-Myers Squibb Company | Amino-substituted tetracyclic compounds useful as anti-inflammatory agents and pharmaceutical compositions comprising same |
| BR0114978A (pt) | 2000-10-26 | 2004-04-20 | Tularik Inc | Composições e métodos que são úteis no tratamento de condições ou doenças inflamatórias, metabólicas, e proliferativas celulares |
| AR037641A1 (es) | 2001-12-05 | 2004-11-17 | Tularik Inc | Moduladores de inflamacion |
| DE10237722A1 (de) | 2002-08-17 | 2004-08-19 | Aventis Pharma Deutschland Gmbh | Indol- oder Benzimidazolderivate zur Modulation der IKappaB-Kinase |
| EP1556053A4 (en) | 2002-10-31 | 2006-04-19 | Amgen Inc | ANTI-INFLAMMATORY AGENTS |
| TW200616967A (en) | 2004-06-24 | 2006-06-01 | Smithkline Beecham Corp | Novel indazole carboxamides and their use |
| TW200626142A (en) | 2004-09-21 | 2006-08-01 | Glaxo Group Ltd | Chemical compounds |
| US8063071B2 (en) | 2007-10-31 | 2011-11-22 | GlaxoSmithKline, LLC | Chemical compounds |
| KR20080021077A (ko) | 2005-06-30 | 2008-03-06 | 스미스클라인 비참 코포레이션 | 화합물 |
| EP2266561A3 (en) * | 2005-09-07 | 2011-05-18 | Merck Serono S.A. | IKK Inhibitors for the Treatment of Endometriosis |
| US20090175852A1 (en) | 2006-06-06 | 2009-07-09 | Schering Corporation | Imidazopyrazines as protein kinase inhibitors |
| EP2489667B1 (en) * | 2006-12-13 | 2015-04-15 | ASKA Pharmaceutical Co., Ltd. | Quinoxaline derivative |
| AR065804A1 (es) | 2007-03-23 | 2009-07-01 | Smithkline Beecham Corp | Compuesto de indol carboxamida, composicion farmaceutica que lo comprende y uso de dicho compuesto para preparar un medicamento |
| US11969501B2 (en) | 2008-04-21 | 2024-04-30 | Dompé Farmaceutici S.P.A. | Auris formulations for treating otic diseases and conditions |
| US9132087B2 (en) | 2008-04-21 | 2015-09-15 | Otonomy, Inc. | Auris formulations for treating otic diseases and conditions |
| WO2010000903A2 (es) * | 2008-06-30 | 2010-01-07 | Centro De Investigaciones Energéticas, Medioambientales Y Tecnológicas (Ciemat) | Composición capaz de modular la actividad de ikkalpha para el tratamiento de enfermedades que cursan con acantolisis |
| RU2504544C2 (ru) | 2008-10-02 | 2014-01-20 | Асахи Касеи Фарма Корпорейшн | 8-замещенные производные изохинолина и их применение |
| WO2010102968A1 (en) | 2009-03-10 | 2010-09-16 | Glaxo Group Limited | Indole derivatives as ikk2 inhibitors |
| CN109689027A (zh) | 2016-06-29 | 2019-04-26 | 奥德纳米有限公司 | 甘油三酯耳用制剂及其用途 |
| EP3494994A1 (en) * | 2017-12-07 | 2019-06-12 | Universität zu Köln | Combinations of ripk1- and ikk-inhibitors for the prevention or treatment of immune diseases |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6077701A (en) * | 1997-12-30 | 2000-06-20 | Chiron Corporation | Ikkβ regulates transcription factors |
| AU3070501A (en) * | 2000-02-12 | 2001-08-20 | Astrazeneca Ab | Heteroaromatic carboxamide derivatives and their use as inhibitors of the enzyme IKK-2 |
| AU3741801A (en) * | 2000-03-15 | 2001-09-24 | Aventis Pharma Gmbh | Substituted beta-carbolines with ikb-kinase inhibiting activity |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4160097A (en) * | 1977-01-07 | 1979-07-03 | Westwind Pharmaceuticals, Inc. | 1-(2-Phenylureylene)imidazoles |
| US5851812A (en) * | 1997-07-01 | 1998-12-22 | Tularik Inc. | IKK-β proteins, nucleic acids and methods |
| US6235740B1 (en) * | 1997-08-25 | 2001-05-22 | Bristol-Myers Squibb Co. | Imidazoquinoxaline protein tyrosine kinase inhibitors |
| US6960585B2 (en) * | 2000-10-03 | 2005-11-01 | Bristol-Myers Squibb Company | Amino-substituted tetracyclic compounds useful as anti-inflammatory agents and pharmaceutical compositions comprising same |
-
2002
- 2002-02-01 MX MXPA03006817A patent/MXPA03006817A/es active IP Right Grant
- 2002-02-01 AU AU2002247059A patent/AU2002247059B2/en not_active Ceased
- 2002-02-01 JP JP2002560582A patent/JP2004529088A/ja active Pending
- 2002-02-01 CZ CZ20032287A patent/CZ20032287A3/cs unknown
- 2002-02-01 PL PL02364111A patent/PL364111A1/xx not_active Application Discontinuation
- 2002-02-01 WO PCT/US2002/003060 patent/WO2002060386A2/en not_active Ceased
- 2002-02-01 EP EP02714815A patent/EP1363993A4/en not_active Withdrawn
- 2002-02-01 CA CA002436770A patent/CA2436770A1/en not_active Abandoned
- 2002-02-01 HU HU0304045A patent/HUP0304045A3/hu unknown
-
2003
- 2003-07-31 NO NO20033429A patent/NO20033429L/no not_active Application Discontinuation
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6077701A (en) * | 1997-12-30 | 2000-06-20 | Chiron Corporation | Ikkβ regulates transcription factors |
| AU3070501A (en) * | 2000-02-12 | 2001-08-20 | Astrazeneca Ab | Heteroaromatic carboxamide derivatives and their use as inhibitors of the enzyme IKK-2 |
| AU3741801A (en) * | 2000-03-15 | 2001-09-24 | Aventis Pharma Gmbh | Substituted beta-carbolines with ikb-kinase inhibiting activity |
Also Published As
| Publication number | Publication date |
|---|---|
| NO20033429L (no) | 2003-09-24 |
| NO20033429D0 (no) | 2003-07-31 |
| PL364111A1 (en) | 2004-12-13 |
| WO2002060386A3 (en) | 2002-10-10 |
| MXPA03006817A (es) | 2003-11-13 |
| HUP0304045A2 (hu) | 2004-04-28 |
| HUP0304045A3 (en) | 2005-05-30 |
| WO2002060386A2 (en) | 2002-08-08 |
| CZ20032287A3 (cs) | 2004-02-18 |
| EP1363993A2 (en) | 2003-11-26 |
| EP1363993A4 (en) | 2008-11-12 |
| CA2436770A1 (en) | 2002-08-08 |
| JP2004529088A (ja) | 2004-09-24 |
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