AU2002217287A1 - Benzo(f) isoindol derivatives and their use as ep4 receptor ligands - Google Patents
Benzo(f) isoindol derivatives and their use as ep4 receptor ligandsInfo
- Publication number
- AU2002217287A1 AU2002217287A1 AU2002217287A AU1728702A AU2002217287A1 AU 2002217287 A1 AU2002217287 A1 AU 2002217287A1 AU 2002217287 A AU2002217287 A AU 2002217287A AU 1728702 A AU1728702 A AU 1728702A AU 2002217287 A1 AU2002217287 A1 AU 2002217287A1
- Authority
- AU
- Australia
- Prior art keywords
- benzo
- receptor ligands
- isoindol
- derivatives
- isoindol derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
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- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Immunology (AREA)
- Ophthalmology & Optometry (AREA)
- Psychology (AREA)
- Reproductive Health (AREA)
- Psychiatry (AREA)
- Vascular Medicine (AREA)
- Otolaryngology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0031295.9A GB0031295D0 (en) | 2000-12-21 | 2000-12-21 | Naphthalene derivatives |
| GB0031295 | 2000-12-21 | ||
| PCT/GB2001/005706 WO2002050033A1 (en) | 2000-12-21 | 2001-12-20 | Benzo(f) isoindol derivatives and their use as ep4 receptor ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2002217287A1 true AU2002217287A1 (en) | 2002-07-01 |
Family
ID=9905625
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2002217287A Abandoned AU2002217287A1 (en) | 2000-12-21 | 2001-12-20 | Benzo(f) isoindol derivatives and their use as ep4 receptor ligands |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7173047B2 (enExample) |
| EP (1) | EP1343759A1 (enExample) |
| JP (1) | JP4398150B2 (enExample) |
| AU (1) | AU2002217287A1 (enExample) |
| GB (1) | GB0031295D0 (enExample) |
| WO (1) | WO2002050033A1 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HN2001000224A (es) | 2000-10-19 | 2002-06-13 | Pfizer | Compuestos de imidazol condensado con arilo o heteroarilo como agentes anti - inflamatorios y analgesicos. |
| GB0103269D0 (en) * | 2001-02-09 | 2001-03-28 | Glaxo Group Ltd | Napthalene derivatives |
| MXPA04009243A (es) | 2002-04-12 | 2005-06-08 | Pfizer | Uso de ligandos para el receptor ep4 en el tratamiento de enfermedades vinculadas a il-6. |
| WO2004073589A2 (en) * | 2003-02-24 | 2004-09-02 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with g-protein coupled receptor prostaglandin e2 ep4 (prostaglandin e2 ep4) |
| RU2006137076A (ru) * | 2004-04-20 | 2008-04-27 | Пфайзер Продактс Инк. (Us) | Комбинации, содержащие лиганды рецептора альфа-2-дельта |
| JP5289046B2 (ja) * | 2005-05-19 | 2013-09-11 | メルク カナダ インコーポレイテッド | Ep4アンタゴニストとしてのキノリン誘導体 |
| SG169378A1 (en) * | 2006-02-03 | 2011-03-30 | Glaxo Group Ltd | Benzoisoindole derivatives for the treatment of pain |
| UY30121A1 (es) | 2006-02-03 | 2007-08-31 | Glaxo Group Ltd | Nuevos compuestos |
| GB0602900D0 (en) * | 2006-02-13 | 2006-03-22 | Glaxo Group Ltd | Novel Compounds |
| GB0615105D0 (en) | 2006-07-28 | 2006-09-06 | Glaxo Group Ltd | Novel compounds |
| GB0615111D0 (en) * | 2006-07-28 | 2006-09-06 | Glaxo Group Ltd | Novel compounds |
| GB0616498D0 (en) * | 2006-08-18 | 2006-09-27 | Glaxo Group Ltd | Novel compounds |
| BRPI0720254A2 (pt) | 2006-12-15 | 2014-01-07 | Glaxo Group Ltd | Derivados de benzamida como agonistas do receptor ep4 |
| GB0721611D0 (en) | 2007-11-02 | 2007-12-12 | Glaxo Group Ltd | Novel compounds |
| JPWO2010087425A1 (ja) | 2009-01-30 | 2012-08-02 | 国立大学法人京都大学 | 前立腺癌の進行抑制剤および進行抑制方法 |
| KR20120093955A (ko) | 2009-10-14 | 2012-08-23 | 젬머스 파마 인코포레이티드 | 바이러스 감염에 대한 병용 요법 치료 |
| WO2014143591A1 (en) * | 2013-03-12 | 2014-09-18 | Allergan, Inc. | Inhibition of neovascularization by simultaneous inhibition of prostanoid ip and ep4 receptors |
| JP6694385B2 (ja) | 2013-08-09 | 2020-05-13 | アーデリクス,インコーポレーテッド | リン酸塩輸送阻害のための化合物及び方法 |
| CR20180323A (es) | 2015-11-20 | 2018-08-06 | Idorsia Pharmaceuticals Ltd | Derivados de indol n-sustituídos como moduladores de los receptores de pge2 |
| AU2018268311B2 (en) | 2017-05-18 | 2022-02-10 | Idorsia Pharmaceuticals Ltd | Pyrimidine derivatives as PGE2 receptor modulators |
| EP3625224B1 (en) | 2017-05-18 | 2021-08-04 | Idorsia Pharmaceuticals Ltd | N-substituted indole derivatives |
| US11325899B2 (en) | 2017-05-18 | 2022-05-10 | Idorsia Pharmaceuticals Ltd | Benzofurane and benzothiophene derivatives as PGE2 receptor modulators |
| WO2018210994A1 (en) | 2017-05-18 | 2018-11-22 | Idorsia Pharmaceuticals Ltd | Phenyl derivatives as pge2 receptor modulators |
| WO2018210992A1 (en) | 2017-05-18 | 2018-11-22 | Idorsia Pharmaceuticals Ltd | Pyrimidine derivatives |
| EP3972599B1 (en) | 2019-05-21 | 2025-10-22 | Ardelyx, Inc. | Combination for lowering serum phosphate in a patient |
| WO2022102731A1 (ja) | 2020-11-13 | 2022-05-19 | 小野薬品工業株式会社 | Ep4拮抗薬と免疫チェックポイント阻害物質との併用によるがん治療 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3909864B2 (ja) * | 1995-07-26 | 2007-04-25 | 小野薬品工業株式会社 | ナフチルオキシ酢酸誘導体およびそれらを有効成分として含有する薬剤 |
| US6437146B1 (en) * | 1998-09-25 | 2002-08-20 | Fujisawa Pharmaceutical Co., Ltd. | Oxazole compounds as prostaglandin e2 agonists or antagonists |
| ES2274378T3 (es) * | 1999-08-10 | 2007-05-16 | Glaxo Group Limited | Ligando del receptor ep4 y uso contra dolor neuropatico, cancer de colon,hiv y migraña. |
| GB0031302D0 (en) * | 2000-12-21 | 2001-01-31 | Glaxo Group Ltd | Napthalene derivatives |
-
2000
- 2000-12-21 GB GBGB0031295.9A patent/GB0031295D0/en not_active Ceased
-
2001
- 2001-12-20 JP JP2002551530A patent/JP4398150B2/ja not_active Expired - Fee Related
- 2001-12-20 WO PCT/GB2001/005706 patent/WO2002050033A1/en not_active Ceased
- 2001-12-20 EP EP01271356A patent/EP1343759A1/en not_active Withdrawn
- 2001-12-20 AU AU2002217287A patent/AU2002217287A1/en not_active Abandoned
- 2001-12-20 US US10/450,639 patent/US7173047B2/en not_active Expired - Fee Related
-
2006
- 2006-07-14 US US11/486,698 patent/US20060252799A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP4398150B2 (ja) | 2010-01-13 |
| US7173047B2 (en) | 2007-02-06 |
| GB0031295D0 (en) | 2001-01-31 |
| US20060252799A1 (en) | 2006-11-09 |
| US20040087624A1 (en) | 2004-05-06 |
| WO2002050033A1 (en) | 2002-06-27 |
| JP2004517847A (ja) | 2004-06-17 |
| EP1343759A1 (en) | 2003-09-17 |
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