AU2002217287A1 - Benzo(f) isoindol derivatives and their use as ep4 receptor ligands - Google Patents
Benzo(f) isoindol derivatives and their use as ep4 receptor ligandsInfo
- Publication number
- AU2002217287A1 AU2002217287A1 AU2002217287A AU1728702A AU2002217287A1 AU 2002217287 A1 AU2002217287 A1 AU 2002217287A1 AU 2002217287 A AU2002217287 A AU 2002217287A AU 1728702 A AU1728702 A AU 1728702A AU 2002217287 A1 AU2002217287 A1 AU 2002217287A1
- Authority
- AU
- Australia
- Prior art keywords
- benzo
- receptor ligands
- isoindol
- derivatives
- isoindol derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
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- Diabetes (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Physical Education & Sports Medicine (AREA)
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- Endocrinology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Ophthalmology & Optometry (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Immunology (AREA)
- Psychiatry (AREA)
- Reproductive Health (AREA)
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0031295.9A GB0031295D0 (en) | 2000-12-21 | 2000-12-21 | Naphthalene derivatives |
GB0031295 | 2000-12-21 | ||
PCT/GB2001/005706 WO2002050033A1 (en) | 2000-12-21 | 2001-12-20 | Benzo(f) isoindol derivatives and their use as ep4 receptor ligands |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2002217287A1 true AU2002217287A1 (en) | 2002-07-01 |
Family
ID=9905625
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2002217287A Abandoned AU2002217287A1 (en) | 2000-12-21 | 2001-12-20 | Benzo(f) isoindol derivatives and their use as ep4 receptor ligands |
Country Status (6)
Country | Link |
---|---|
US (2) | US7173047B2 (en) |
EP (1) | EP1343759A1 (en) |
JP (1) | JP4398150B2 (en) |
AU (1) | AU2002217287A1 (en) |
GB (1) | GB0031295D0 (en) |
WO (1) | WO2002050033A1 (en) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HN2001000224A (en) | 2000-10-19 | 2002-06-13 | Pfizer | IMIDAZOL COMPOUNDS CONDENSED WITH ARILO OR HETEROARILO AS ANTI - INFLAMMATORY AND ANALGESIC AGENTS. |
GB0103269D0 (en) * | 2001-02-09 | 2001-03-28 | Glaxo Group Ltd | Napthalene derivatives |
CN101023946A (en) | 2002-04-12 | 2007-08-29 | 美国辉瑞有限公司 | Use of EP4 receptor ligands in the treatment of IL-6 involved diseases |
WO2004073589A2 (en) * | 2003-02-24 | 2004-09-02 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with g-protein coupled receptor prostaglandin e2 ep4 (prostaglandin e2 ep4) |
CN1946391A (en) * | 2004-04-20 | 2007-04-11 | 辉瑞产品公司 | Combinations comprising alpha-2-delta ligands |
AU2006246930C1 (en) | 2005-05-19 | 2012-01-19 | Merck Canada Inc. | Quinoline derivatives as EP4 antagonists |
UY30121A1 (en) | 2006-02-03 | 2007-08-31 | Glaxo Group Ltd | NEW COMPOUNDS |
WO2007088189A1 (en) * | 2006-02-03 | 2007-08-09 | Glaxo Group Limited | Benzoisoindole derivatives for the treatment of pain |
GB0602900D0 (en) | 2006-02-13 | 2006-03-22 | Glaxo Group Ltd | Novel Compounds |
GB0615105D0 (en) * | 2006-07-28 | 2006-09-06 | Glaxo Group Ltd | Novel compounds |
GB0615111D0 (en) * | 2006-07-28 | 2006-09-06 | Glaxo Group Ltd | Novel compounds |
GB0616498D0 (en) * | 2006-08-18 | 2006-09-27 | Glaxo Group Ltd | Novel compounds |
JP5069752B2 (en) | 2006-12-15 | 2012-11-07 | グラクソ グループ リミテッド | Benzamide derivatives as EP4 receptor agonists |
GB0721611D0 (en) | 2007-11-02 | 2007-12-12 | Glaxo Group Ltd | Novel compounds |
EP2392323A4 (en) | 2009-01-30 | 2012-09-26 | Univ Kyoto | Prostate cancer progression inhibitor and progression inhibition method |
WO2011047048A1 (en) | 2009-10-14 | 2011-04-21 | Gemmus Pharma, Inc. | Combination therapy treatment for viral infections |
US9295665B2 (en) | 2013-03-12 | 2016-03-29 | Allergan, Inc. | Inhibition of neovascularization by simultaneous inhibition of prostanoid IP and EP4 receptors |
EP3884935B1 (en) | 2013-08-09 | 2023-06-14 | Ardelyx, Inc. | Compounds and methods for inhibiting phosphate transport |
CR20180323A (en) | 2015-11-20 | 2018-08-06 | Idorsia Pharmaceuticals Ltd | DERIVATIVES OF INDOL N-SUBSTITUTES AS MODULATORS OF PGE2 RECEIVERS |
RS62441B1 (en) | 2017-05-18 | 2021-11-30 | Idorsia Pharmaceuticals Ltd | N-substituted indole derivatives |
WO2018210987A1 (en) | 2017-05-18 | 2018-11-22 | Idorsia Pharmaceuticals Ltd | Benzofurane and benzothiophene derivatives as pge2 receptor modulators |
RS62440B1 (en) | 2017-05-18 | 2021-11-30 | Idorsia Pharmaceuticals Ltd | Phenyl derivatives as pge2 receptor modulators |
EP3625223B1 (en) | 2017-05-18 | 2021-08-11 | Idorsia Pharmaceuticals Ltd | Pyrimidine derivatives |
CN110612299A (en) | 2017-05-18 | 2019-12-24 | 爱杜西亚药品有限公司 | Pyrimidine derivatives as PGE2 receptor modulators |
US20200368223A1 (en) | 2019-05-21 | 2020-11-26 | Ardelyx, Inc. | Methods for inhibiting phosphate transport |
TW202228674A (en) | 2020-11-13 | 2022-08-01 | 日商小野藥品工業股份有限公司 | Cancer treatment with combination of ep4 antagonist and immune checkpoint inhibitor |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
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EP0845451A4 (en) | 1995-07-26 | 1999-10-13 | Ono Pharmaceutical Co | Naphthyloxyacetic acid derivatives and drugs comprising the same as active ingredients |
US6437146B1 (en) * | 1998-09-25 | 2002-08-20 | Fujisawa Pharmaceutical Co., Ltd. | Oxazole compounds as prostaglandin e2 agonists or antagonists |
ES2225199T3 (en) * | 1999-08-10 | 2005-03-16 | Glaxo Group Limited | USE OF EP4 RECEIVER LIGANDS IN THE TREATMENT OF NEUROPATHIC PAIN. |
GB0031302D0 (en) * | 2000-12-21 | 2001-01-31 | Glaxo Group Ltd | Napthalene derivatives |
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2000
- 2000-12-21 GB GBGB0031295.9A patent/GB0031295D0/en not_active Ceased
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2001
- 2001-12-20 EP EP01271356A patent/EP1343759A1/en not_active Withdrawn
- 2001-12-20 WO PCT/GB2001/005706 patent/WO2002050033A1/en active Application Filing
- 2001-12-20 US US10/450,639 patent/US7173047B2/en not_active Expired - Fee Related
- 2001-12-20 AU AU2002217287A patent/AU2002217287A1/en not_active Abandoned
- 2001-12-20 JP JP2002551530A patent/JP4398150B2/en not_active Expired - Fee Related
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2006
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JP4398150B2 (en) | 2010-01-13 |
US20060252799A1 (en) | 2006-11-09 |
JP2004517847A (en) | 2004-06-17 |
US20040087624A1 (en) | 2004-05-06 |
EP1343759A1 (en) | 2003-09-17 |
WO2002050033A1 (en) | 2002-06-27 |
GB0031295D0 (en) | 2001-01-31 |
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