AU2001293702A1 - 3-indolyl-4-phenyl-1h-pyrrole-2,5-dione derivatives as inhibitors of glycogen synthase kinase-3beta - Google Patents

Info

Publication number

AU2001293702A1

AU2001293702A1 AU2001293702A AU9370201A AU2001293702A1 AU 2001293702 A1 AU2001293702 A1 AU 2001293702A1 AU 2001293702 A AU2001293702 A AU 2001293702A AU 9370201 A AU9370201 A AU 9370201A AU 2001293702 A1 AU2001293702 A1 AU 2001293702A1

Authority

AU

Australia

Prior art keywords

heteroalkyl

compound

hydrogen

dione

alkyl

Prior art date

2000-07-27

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Abandoned

Links

• Espacenet
• Global Dossier
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• 102000019058 Glycogen Synthase Kinase 3 beta Human genes 0.000 title claims description 52
• 239000003112 inhibitor Substances 0.000 title claims description 21
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• 150000001875 compounds Chemical class 0.000 claims description 231
• -1 cyano, nitro, amino Chemical group 0.000 claims description 194
• 229910052739 hydrogen Inorganic materials 0.000 claims description 82
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• 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 74
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• 125000000217 alkyl group Chemical group 0.000 claims description 63
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• 125000000623 heterocyclic group Chemical group 0.000 claims description 51
• 238000000034 method Methods 0.000 claims description 50
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• 125000000753 cycloalkyl group Chemical group 0.000 claims description 34
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• 239000003814 drug Substances 0.000 claims description 19
• UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 18
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• 125000003545 alkoxy group Chemical group 0.000 claims description 15
• 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 15
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• 125000004663 dialkyl amino group Chemical group 0.000 claims description 12
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