ATE83801T1 - Verfahren und mittel zur herstellung eines proteins mit der gleichen igg-spezifizitaet wie protein g. - Google Patents

Verfahren und mittel zur herstellung eines proteins mit der gleichen igg-spezifizitaet wie protein g.

Info

Publication number
ATE83801T1
ATE83801T1 AT87902174T AT87902174T ATE83801T1 AT E83801 T1 ATE83801 T1 AT E83801T1 AT 87902174 T AT87902174 T AT 87902174T AT 87902174 T AT87902174 T AT 87902174T AT E83801 T1 ATE83801 T1 AT E83801T1
Authority
AT
Austria
Prior art keywords
protein
producing
methods
same igg
specificity
Prior art date
Application number
AT87902174T
Other languages
English (en)
Inventor
Bengt Mikael Guss
Kjell Martin Lindberg
Jan Ingmar Flock
Carl Erik Mathias Uhlen
Original Assignee
Pharmacia Lkb Biotech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Lkb Biotech filed Critical Pharmacia Lkb Biotech
Application granted granted Critical
Publication of ATE83801T1 publication Critical patent/ATE83801T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/705—Fusion polypeptide containing domain for protein-protein interaction containing a protein-A fusion
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/971—Capture of complex after antigen-antibody reaction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT87902174T 1986-03-21 1987-03-20 Verfahren und mittel zur herstellung eines proteins mit der gleichen igg-spezifizitaet wie protein g. ATE83801T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE8601325A SE459662B (sv) 1986-03-21 1986-03-21 Hybrid-dna-molekyl som kodar foer ett protein med samma igg specificitet som protein g, plasmid innehaallande densamma samt foerfarande foer framstaellning av proteinet
EP87902174A EP0262192B1 (de) 1986-03-21 1987-03-20 Verfahren und mittel zur herstellung eines proteins mit der gleichen igg-spezifizität wie protein g
PCT/SE1987/000145 WO1987005631A1 (en) 1986-03-21 1987-03-20 METHOD AND MEANS FOR PRODUCING A PROTEIN HAVING THE SAME IgG SPECIFICITY AS PROTEIN G

Publications (1)

Publication Number Publication Date
ATE83801T1 true ATE83801T1 (de) 1993-01-15

Family

ID=20363924

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87902174T ATE83801T1 (de) 1986-03-21 1987-03-20 Verfahren und mittel zur herstellung eines proteins mit der gleichen igg-spezifizitaet wie protein g.

Country Status (7)

Country Link
US (2) US5976861A (de)
EP (1) EP0262192B1 (de)
JP (3) JP2514061B2 (de)
AT (1) ATE83801T1 (de)
DE (2) DE262192T1 (de)
SE (1) SE459662B (de)
WO (1) WO1987005631A1 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4977247A (en) * 1986-02-14 1990-12-11 Genex Corporation Immobilized protein G variants and the use thereof
US5312901A (en) * 1986-02-14 1994-05-17 Pharmacia Lkb Biotechnology Ab Cloned streptococcal genes encoding protein G and their use to construct recombinant microorganisms to produce protein G
US4954618A (en) * 1986-02-14 1990-09-04 Genex Corporation Cloned streptococcal genes encoding protein G and their use to construct recombinant microorganisms to produce protein G
US5082773A (en) * 1986-02-14 1992-01-21 Pharmacia Lkb Biotechnology Ab Cloned streptococcal genes encoding protein G and their use to construct recombinant microorganisms to produce protein G
US5229492A (en) * 1986-02-14 1993-07-20 Pharmacia Lkb Biotechnology Ab Cloned streptococcal genes encoding protein G and their use to construct recombinant microorganisms to produce protein G
US4956296A (en) * 1987-06-19 1990-09-11 Genex Corporation Cloned streptococcal genes encoding protein G and their use to construct recombinant microorganisms to produce protein G
EP0293391A4 (de) * 1986-02-14 1989-06-21 Genex Corp Klonierte streptokokkengene, kodierend für protein-g und verwendung zur herstellung rekombinanter mikroorganismen zur erzeugung von protein-g.
SE459662B (sv) * 1986-03-21 1989-07-24 Pharmacia Ab Hybrid-dna-molekyl som kodar foer ett protein med samma igg specificitet som protein g, plasmid innehaallande densamma samt foerfarande foer framstaellning av proteinet
DE3887750T2 (de) * 1987-11-20 1994-09-15 Creative Biomolecules Inc Selektive entfernung von immunkomplexen.
US5084398A (en) * 1987-11-20 1992-01-28 Creative Biomolecules Selective removal of immune complexes
US5243040A (en) * 1987-11-20 1993-09-07 Creative Biomolecules DNA encoding a protein which enables selective removal of immune complexes
SE501169C2 (sv) * 1988-02-05 1994-11-28 Aake Nygren Framställning av serumalbuminbindande fusionsproteiner vilka innehåller protein G-domäner
WO1990012877A1 (en) * 1989-04-19 1990-11-01 Cetus Corporation Multifunctional m-csf proteins and genes encoding therefor
SE466259B (sv) * 1990-05-31 1992-01-20 Arne Forsgren Protein d - ett igd-bindande protein fraan haemophilus influenzae, samt anvaendning av detta foer analys, vacciner och uppreningsaendamaal
SE9201331D0 (sv) 1992-04-28 1992-04-28 Hightech Receptor C O Active Protein l och hybridproteiner daerav
WO1995006125A1 (en) * 1993-08-23 1995-03-02 Applied Immune Sciences, Inc. CHIMERIC RECEPTOR CONTAINING ONE IgG BINDING DOMAIN OF BOTH PROTEIN A AND PROTEIN G
JP4685294B2 (ja) 2001-09-18 2011-05-18 株式会社カネカ 新規ペプチド、生産方法、新規吸着体、吸着器および吸着方法
US7157562B1 (en) * 2003-04-14 2007-01-02 The United States Of America As Represented By The Secretary Of The Army Bioprocess for the production of recombinant anti-botulinum toxin antibody
EP2251425B1 (de) 2004-07-06 2016-04-20 Kaneka Corporation Verfahren zur Herstellung eines Protein-A-ähnlichen Proteins unter Verwendung eines Bakteriums der Gattung Brevibacillus
WO2006110292A2 (en) * 2005-03-25 2006-10-19 The Regents Of The University Of California Temperature-triggered immobilization and purification of antibodies
EP2010276B1 (de) * 2006-04-26 2014-01-22 Covidien LP Mehrfachmodus-mikroporationsvorrichtung
GB0621513D0 (en) * 2006-10-30 2006-12-06 Domantis Ltd Novel polypeptides and uses thereof
JP5211041B2 (ja) * 2007-04-23 2013-06-12 シンセラ・テクノロジーズ株式会社 プロテインｇとアビジン類との融合タンパク質
JP5278940B2 (ja) * 2007-11-12 2013-09-04 独立行政法人産業技術総合研究所 安定な抗体結合性タンパク質
US9052304B2 (en) 2009-03-13 2015-06-09 Terrasep, Llc Methods and apparatus for centrifugal liquid chromatography
CN103748221A (zh) 2011-08-04 2014-04-23 独立行政法人产业技术综合研究所 由蛋白g细胞膜外结构域突变体的串联型多聚体组成的新型改性蛋白
EP2881403A4 (de) 2012-08-03 2016-05-18 Nat Inst Of Advanced Ind Scien Scavenger mit protein aus einem tandemmultimer einer mutanten extrazellulären domäne von protein g
US10556944B2 (en) 2013-08-30 2020-02-11 Kaneka Corporation Fab region-binding peptide
CN105814201A (zh) 2013-10-04 2016-07-27 独立行政法人产业技术综合研究所 用接头键合对具有免疫球蛋白G(IgG)的Fc部分的蛋白质具有亲和力的多个结构域之间而成的蛋白质
WO2016136910A1 (ja) 2015-02-26 2016-09-01 株式会社カネカ 改変型Ｆａｂ領域結合性ペプチド
WO2018021012A1 (ja) 2016-07-28 2018-02-01 株式会社カネカ 抗体断片の製造方法
WO2018180205A1 (ja) 2017-03-31 2018-10-04 株式会社カネカ 免疫グロブリン精製用アフィニティー分離マトリックス
JP7118949B2 (ja) 2017-03-31 2022-08-16 株式会社カネカ 安定性改良型免疫グロブリン結合性ペプチド

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US829354A (en) * 1906-02-28 1906-08-21 Bertram Sarrett Cradle-rocking attachment.
DE2426988C2 (de) * 1974-06-04 1985-02-14 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur Trägerbindung biologisch aktiver Proteine
US5151350A (en) * 1982-10-27 1992-09-29 Repligen Corporation Cloned genes encoding recombinant protein a
SE8300693L (sv) * 1983-02-09 1984-08-10 Sven Lofdahl Sett att framstella och isolera proteiner och polypeptider samt en hybridvektor for detta
US4617266A (en) * 1983-04-28 1986-10-14 Genex Corporation Production of Protein A
SE451596B (sv) * 1983-06-22 1987-10-19 Excorim Kb Forfarande for utvinning av protein g
US4704366A (en) * 1984-06-22 1987-11-03 Bio-Rad Laboratories, Inc. Process for binding IgG to protein A
SE459503B (sv) * 1985-05-03 1989-07-10 Excorim Kommanditbolag Hybrid-dna-molekyl innefattande dna-sekvens som kodar foer protein g samt foerfarande foer framstaellning av protein g
US4900660A (en) * 1985-11-25 1990-02-13 University Of Florida Streptococcal fc rc
US4954618A (en) * 1986-02-14 1990-09-04 Genex Corporation Cloned streptococcal genes encoding protein G and their use to construct recombinant microorganisms to produce protein G
US4956296A (en) * 1987-06-19 1990-09-11 Genex Corporation Cloned streptococcal genes encoding protein G and their use to construct recombinant microorganisms to produce protein G
EP0293391A4 (de) * 1986-02-14 1989-06-21 Genex Corp Klonierte streptokokkengene, kodierend für protein-g und verwendung zur herstellung rekombinanter mikroorganismen zur erzeugung von protein-g.
US5082773A (en) * 1986-02-14 1992-01-21 Pharmacia Lkb Biotechnology Ab Cloned streptococcal genes encoding protein G and their use to construct recombinant microorganisms to produce protein G
US4977247A (en) * 1986-02-14 1990-12-11 Genex Corporation Immobilized protein G variants and the use thereof
SE459662B (sv) * 1986-03-21 1989-07-24 Pharmacia Ab Hybrid-dna-molekyl som kodar foer ett protein med samma igg specificitet som protein g, plasmid innehaallande densamma samt foerfarande foer framstaellning av proteinet
US5084559A (en) * 1987-03-27 1992-01-28 Repligen Corporation Protein a domain mutants
US4945157A (en) * 1988-05-27 1990-07-31 University Of Florida Novel Extraction procedure for protein G

Also Published As

Publication number Publication date
JP2764022B2 (ja) 1998-06-11
JP2764021B2 (ja) 1998-06-11
JPH08205876A (ja) 1996-08-13
SE8601325L (sv) 1987-09-22
SE459662B (sv) 1989-07-24
JPH08205875A (ja) 1996-08-13
JPS63503032A (ja) 1988-11-10
WO1987005631A1 (en) 1987-09-24
US5756670A (en) 1998-05-26
EP0262192A1 (de) 1988-04-06
DE3783191D1 (de) 1993-02-04
DE3783191T2 (de) 1993-04-29
DE262192T1 (de) 1988-08-11
JP2514061B2 (ja) 1996-07-10
US5976861A (en) 1999-11-02
SE8601325D0 (sv) 1986-03-21
EP0262192B1 (de) 1992-12-23

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEFA Change of the company name
REN Ceased due to non-payment of the annual fee