ATE73459T1 - Pharmazeutische zusammensetzungen, welche ein dipeptid enthalten. - Google Patents

Pharmazeutische zusammensetzungen, welche ein dipeptid enthalten.

Info

Publication number
ATE73459T1
ATE73459T1 AT85810246T AT85810246T ATE73459T1 AT E73459 T1 ATE73459 T1 AT E73459T1 AT 85810246 T AT85810246 T AT 85810246T AT 85810246 T AT85810246 T AT 85810246T AT E73459 T1 ATE73459 T1 AT E73459T1
Authority
AT
Austria
Prior art keywords
pharmaceutical compositions
dipeptide
compositions containing
ulcers
lys
Prior art date
Application number
AT85810246T
Other languages
German (de)
English (en)
Inventor
Jin-Emon Konishi
Original Assignee
Nippon Zoki Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Zoki Pharmaceutical Co filed Critical Nippon Zoki Pharmaceutical Co
Application granted granted Critical
Publication of ATE73459T1 publication Critical patent/ATE73459T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
    • C07K5/06069—Ser-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06147—Dipeptides with the first amino acid being heterocyclic and His-amino acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT85810246T 1984-05-24 1985-05-24 Pharmazeutische zusammensetzungen, welche ein dipeptid enthalten. ATE73459T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP59105098A JPS60248618A (ja) 1984-05-24 1984-05-24 ジペプチドを含有する潰瘍治療剤
EP85810246A EP0162813B1 (en) 1984-05-24 1985-05-24 Pharmaceutical compositions containing a dipeptide

Publications (1)

Publication Number Publication Date
ATE73459T1 true ATE73459T1 (de) 1992-03-15

Family

ID=14398420

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85810246T ATE73459T1 (de) 1984-05-24 1985-05-24 Pharmazeutische zusammensetzungen, welche ein dipeptid enthalten.

Country Status (5)

Country Link
US (1) US4637996A (enExample)
EP (1) EP0162813B1 (enExample)
JP (1) JPS60248618A (enExample)
AT (1) ATE73459T1 (enExample)
DE (1) DE3585556D1 (enExample)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS260899B1 (en) * 1986-11-07 1989-01-12 Evzen Kasafirek Remedy for gastrointestinal diseases
US6331318B1 (en) * 1994-09-30 2001-12-18 Emisphere Technologies Inc. Carbon-substituted diketopiperazine delivery systems
CA2128429A1 (en) * 1992-01-21 1993-07-22 Howard Alliger Method of treating small mouth ulcers
YU86001A (sh) * 1999-06-07 2004-07-15 Altana Pharma Ag. Novi preparat i oblik, u kojem se daje lek, koji sadrži aktivno jedinjenje labilno prema kiselini
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
WO2003080149A2 (en) 2002-03-20 2003-10-02 Mannkind Corporation Inhalation apparatus
ATE486064T1 (de) 2004-08-20 2010-11-15 Mannkind Corp Katalyse der diketopiperazinsynthese
HUE025151T2 (en) 2004-08-23 2016-01-28 Mannkind Corp Diceto-piperazine salts for drug delivery
KR101486397B1 (ko) 2005-09-14 2015-01-28 맨카인드 코포레이션 활성제에 대한 결정질 미립자 표면의 친화력의 증가를 기반으로 하는 약물 제제화의 방법
KR20080096809A (ko) 2006-02-22 2008-11-03 맨카인드 코포레이션 디케토피페라진 및 활성제를 포함하는 마이크로입자의 약학특성의 개선 방법
WO2009012393A1 (en) * 2007-07-18 2009-01-22 The Curators Of The University Of Missouri Pharmaceutical composition comprising a proton pump inhibitor and protein component
ES2929343T3 (es) 2008-06-13 2022-11-28 Mannkind Corp Inhalador de polvo seco accionado por aspiración para la administración de fármacos
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
MX2010014240A (es) 2008-06-20 2011-03-25 Mankind Corp Un metodo y aparato interactivo para perfilar en tiempo real esfuerzos de inhalacion.
TWI494123B (zh) 2008-08-11 2015-08-01 Mannkind Corp 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
WO2010105094A1 (en) 2009-03-11 2010-09-16 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
US20100297651A1 (en) * 2009-05-21 2010-11-25 The General Hospital Corporation Methods of Modulating Vesicular Trafficking
MY157166A (en) 2009-06-12 2016-05-13 Mankind Corp Diketopiperazine microparticles with defined specific surface areas
WO2011056889A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
BR112012033060A2 (pt) 2010-06-21 2018-02-27 Mannkind Corp métodos de sistema de liberação de fármaco em pó seco
AU2012236150B2 (en) 2011-04-01 2016-03-31 Mannkind Corporation Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
BR112014009686A2 (pt) 2011-10-24 2018-08-07 Mannkind Corp composição analgésica inalável, pó seco e método para tratar dor
US10316103B1 (en) 2012-03-30 2019-06-11 Biocare Medical, Llc Systems and methods for anti-Uroplakin III antibodies
AU2013289957B2 (en) 2012-07-12 2017-02-23 Mannkind Corporation Dry powder drug delivery systems and methods
DK2900265T3 (en) 2012-09-27 2018-08-20 Biocare Medical Llc Anti-Uroplakin II Antibodies, Systems and Methods
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
WO2014100220A2 (en) 2012-12-18 2014-06-26 Biocare Medical, Llc Antibody cocktail systems and methods for classification of histologic subtypes in lung cancer
DK2962113T3 (da) 2013-02-28 2019-07-01 Biocare Medical Llc Systemer og fremgangsmåder med anti-p40-antistoffer
KR102246914B1 (ko) 2013-03-15 2021-04-30 맨카인드 코포레이션 미세결정성 디케토피페라진 조성물 및 방법
CN114848614A (zh) 2013-07-18 2022-08-05 曼金德公司 热稳定性干粉药物组合物和方法
EP3030294B1 (en) 2013-08-05 2020-10-07 MannKind Corporation Insufflation apparatus
ES2765423T3 (es) 2013-10-03 2020-06-09 Biocare Medical Llc Sistemas y procedimientos de anticuerpos anti-SOX10
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
WO2017014121A1 (ja) * 2015-07-17 2017-01-26 サントリーホールディングス株式会社 メラニン凝集ホルモン受容体拮抗用組成物
WO2017038799A1 (ja) * 2015-09-04 2017-03-09 サントリーホールディングス株式会社 ウレアーゼ活性阻害剤
EP4157820A4 (en) * 2020-06-01 2024-07-03 Balchem Corporation Metal di-amino acid chelates or metal tri-amino acid chelates

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1459488A (en) * 1974-03-19 1976-12-22 Wyeth John & Brother Ltd Piperazinedione derivatives
US3965260A (en) * 1975-07-07 1976-06-22 John N. McArthur Anti-inflammatory dipeptide
US4127535A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel dipeptides, intermediates therefor, and compositions and methods employing said dipeptides

Also Published As

Publication number Publication date
US4637996A (en) 1987-01-20
JPH0150684B2 (enExample) 1989-10-31
DE3585556D1 (de) 1992-04-16
EP0162813A3 (en) 1989-01-25
EP0162813A2 (en) 1985-11-27
JPS60248618A (ja) 1985-12-09
EP0162813B1 (en) 1992-03-11

Similar Documents

Publication Publication Date Title
ATE73459T1 (de) Pharmazeutische zusammensetzungen, welche ein dipeptid enthalten.
ATE136221T1 (de) Osteo-induktive pharmazeutische formulierungen
AU6819294A (en) Oral drug delivery compositions and methods
AU541747B2 (en) N-(vinblastinoyl-23)derivatives of amino acid and peptides
DK10191D0 (da) Hidtil ukendte peptider
HUP0000589A2 (hu) Vizes peptid készítmények
NZ248377A (en) Use of interleukin-1 beta protease and interleukin-1 beta protease inhibitors
NO157935C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive polypeptider.
EP0341915A3 (en) Anti-aggregatory peptides
MX9703643A (es) Metodos para tratamiento de esclerosis multiple usando analogos de peptidos de proteina basica de mielina humana.
UA42747C2 (uk) Похідні пептиду,фармацевтична композиція та спосіб стимулювання секреції гормону росту
AU6020099A (en) Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein
MX9703642A (es) Metodos para el tratamiento de esclerosis multiple utilizando analogos de peptido en la posicion 91 de la proteina basica de mielina humana.
RU94046091A (ru) Полипептидные антагонисты бомбезина, фармацевтическая композиция и способ лечения
WO1996028470A3 (en) Peptide analogues of human myelin basic protein useful in treating multiple sclerosis
ATE377026T1 (de) Behandlung von fettleibigkeit
MY124560A (en) Amino acid compositions and use thereof in immunosuppression
HUT58765A (en) Process for producing peptide compounds and pharmaceutical compositions containing them as active components
CA2071757A1 (en) Implant compositions containing a biologically active protein, peptide or polypeptide
MY103251A (en) Biologically active molecules
BG97123A (bg) Производни на човешка, стимулирана от жлъчните соли, липаза и фармацевтични състави на тяхна основа
EP0796867A4 (en) Peptide, bronchodilator and blood flow ameliorant
DE3569541D1 (en) Pharmacologically active peptides
RU94040865A (ru) Производные пептида и их терапевтически приемлемые соли, способ их получения, фармацевтическая и косметическая композиция с антивирусной активностью
RU95120588A (ru) Циклогексапептиды, их смеси, способ их получения и применения

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties