ATE63563T1 - Synergistin-derivate, deren herstellung und sie enthaltende pharmazeutische zusammensetzungen. - Google Patents
Synergistin-derivate, deren herstellung und sie enthaltende pharmazeutische zusammensetzungen.Info
- Publication number
- ATE63563T1 ATE63563T1 AT87401142T AT87401142T ATE63563T1 AT E63563 T1 ATE63563 T1 AT E63563T1 AT 87401142 T AT87401142 T AT 87401142T AT 87401142 T AT87401142 T AT 87401142T AT E63563 T1 ATE63563 T1 AT E63563T1
- Authority
- AT
- Austria
- Prior art keywords
- derivatives
- synergist
- production
- pharmaceutical compositions
- formula
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 108010015791 Streptogramin A Proteins 0.000 abstract 2
- SUJXEPROYKNZJB-UHFFFAOYSA-N 1-azabicyclo[2.2.2]octane-2-thiol Chemical compound C1CN2C(S)CC1CC2 SUJXEPROYKNZJB-UHFFFAOYSA-N 0.000 abstract 1
- YVMBAUWDIGJRNY-BESUKNQGSA-N 4o8o7q7iu4 Chemical class C1C(=O)C[C@H](O)\C=C(/C)\C=C\CNC(=O)\C=C\[C@@H](C)[C@@H](C(C)C)OC(=O)C2=CCCN2C(=O)C2=COC1=N2.N([C@@H]1C(=O)N[C@@H](C(N2CCC[C@H]2C(=O)N(C)[C@@H](CC=2C=CC(=CC=2)N(C)C)C(=O)N2CCC(=O)C[C@H]2C(=O)N[C@H](C(=O)O[C@@H]1C)C=1C=CC=CC=1)=O)CC)C(=O)C1=NC=CC=C1O YVMBAUWDIGJRNY-BESUKNQGSA-N 0.000 abstract 1
- 239000004599 antimicrobial Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000002147 dimethylamino group Chemical group [H]C([H])([H])N(*)C([H])([H])[H] 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- DAIKHDNSXMZDCU-FQTGFAPKSA-N pristinamycin IIA Chemical compound C1C(=O)C[C@H](O)\C=C(/C)\C=C\CNC(=O)\C=C\[C@@H](C)[C@@H](C(C)C)OC(=O)C2=CCCN2C(=O)C2=COC1=N2 DAIKHDNSXMZDCU-FQTGFAPKSA-N 0.000 abstract 1
- DAIKHDNSXMZDCU-UHFFFAOYSA-N pristinamycin component IIA Natural products C1C(=O)CC(O)C=C(C)C=CCNC(=O)C=CC(C)C(C(C)C)OC(=O)C2=CCCN2C(=O)C2=COC1=N2 DAIKHDNSXMZDCU-UHFFFAOYSA-N 0.000 abstract 1
- DAIKHDNSXMZDCU-OUDXUNEISA-N pristinamycin-IIA Natural products CC(C)[C@H]1OC(=O)C2=CCCN2C(=O)c3coc(CC(=O)C[C@H](O)C=C(C)C=CCNC(=O)C=C[C@@H]1C)n3 DAIKHDNSXMZDCU-OUDXUNEISA-N 0.000 abstract 1
- JOOMGSFOCRDAHL-XKCHLWDXSA-N pristinamycin-IIB Natural products CC(C)[C@@H]1OC(=O)[C@H]2CCCN2C(=O)c3coc(CC(=O)C[C@@H](O)C=C(C)C=CCNC(=O)C=C[C@H]1C)n3 JOOMGSFOCRDAHL-XKCHLWDXSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/19—Antibiotic
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/27—Cyclic peptide or cyclic protein
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Vibration Prevention Devices (AREA)
- Measurement Of Force In General (AREA)
- Lubricants (AREA)
- Polarising Elements (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8607270A FR2599036B1 (fr) | 1986-05-22 | 1986-05-22 | Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent |
| EP87401142A EP0248703B1 (de) | 1986-05-22 | 1987-05-21 | Synergistin-Derivate, deren Herstellung und sie enthaltende pharmazeutische Zusammensetzungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE63563T1 true ATE63563T1 (de) | 1991-06-15 |
Family
ID=9335470
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87401142T ATE63563T1 (de) | 1986-05-22 | 1987-05-21 | Synergistin-derivate, deren herstellung und sie enthaltende pharmazeutische zusammensetzungen. |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US4798827A (de) |
| EP (1) | EP0248703B1 (de) |
| JP (2) | JP2558282B2 (de) |
| KR (1) | KR950001020B1 (de) |
| AT (1) | ATE63563T1 (de) |
| AU (1) | AU601426B2 (de) |
| BR (1) | BR1101133A (de) |
| CA (1) | CA1271297A (de) |
| DE (2) | DE3770048D1 (de) |
| DK (1) | DK172949B1 (de) |
| ES (1) | ES2032457T3 (de) |
| FI (1) | FI84355C (de) |
| FR (1) | FR2599036B1 (de) |
| GE (1) | GEP19960474B (de) |
| GR (1) | GR3002558T3 (de) |
| IE (1) | IE60656B1 (de) |
| IL (1) | IL82564A (de) |
| LU (1) | LU90732I2 (de) |
| LV (1) | LV5268A3 (de) |
| MX (1) | MX9203577A (de) |
| NL (1) | NL300010I2 (de) |
| NZ (1) | NZ220380A (de) |
| PT (1) | PT84934B (de) |
| SU (1) | SU1616520A3 (de) |
| ZA (1) | ZA873639B (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2664894A1 (fr) * | 1990-07-19 | 1992-01-24 | Rhone Poulenc Sante | Nouveaux derives de streptogramines et leur preparation. |
| FR2689518B1 (fr) * | 1992-04-01 | 1995-04-07 | Rhone Poulenc Rorer Sa | Microorganismes, procédé de préparation et utilisation. |
| US5242938A (en) * | 1992-08-27 | 1993-09-07 | Merck & Co., Inc. | Derivatives of virginiamycin M1 |
| IL121821A (en) * | 1993-02-17 | 2000-02-17 | Rhone Poulenc Rorer Sa | Process for purifying a group A minority component of streptogramin some such purified components and their uses |
| FR2722210B1 (fr) * | 1994-07-08 | 1996-08-14 | Rhone Poulenc Rorer Sa | Nouvelles streptogramines et procede de preparation de streptogramines par mutasynthese |
| FR2723373B1 (fr) | 1994-08-02 | 1996-09-13 | Rhone Poulenc Rorer Sa | Forme purifiee de streptogramines, sa preparation et les compositions pharmaceutiques qui la contiennent |
| FR2755857B1 (fr) * | 1996-11-19 | 1998-12-24 | Rhone Poulenc Rorer Sa | Compositions pharmaceutiques stabilisees, a base de quinupristine et de dalfopristine et leur preparation |
| FR2766489B1 (fr) | 1997-07-28 | 1999-08-27 | Rhone Poulenc Rorer Sa | Derives de streptogramines, leur preparation et les compositions qui les contiennent |
| US6187746B1 (en) * | 1997-12-16 | 2001-02-13 | Rhone-Poulenc Rorer S.A. | Pharmaceutical compositions based on dalfopristine and on quinupristine, and preparation thereof |
| FR2796949B1 (fr) * | 1999-07-27 | 2001-09-21 | Aventis Pharma Sa | Derives de streptogramines, leur preparation et les compositions qui les contiennent |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2549063B1 (fr) * | 1983-07-13 | 1985-10-25 | Rhone Poulenc Sante | Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent |
| FR2549065B1 (fr) * | 1983-07-13 | 1985-10-25 | Rhone Poulenc Sante | Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent |
| FR2549062B1 (fr) * | 1983-07-13 | 1985-10-25 | Rhone Poulenc Sante | Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent |
| FR2549064B1 (fr) * | 1983-07-13 | 1985-10-25 | Rhone Poulenc Sante | Nouveaux derives de synergistines utiles pour la preparation de nouveaux medicaments antimicrobiens et leur preparation |
| FR2576022B1 (fr) * | 1985-01-11 | 1987-09-11 | Rhone Poulenc Sante | Nouveaux derives de la pristinamycine ii b, leur preparation et les compositions pharmaceutiques qui les contiennent |
-
1986
- 1986-05-22 FR FR8607270A patent/FR2599036B1/fr not_active Expired
-
1987
- 1987-05-18 IL IL82564A patent/IL82564A/xx not_active IP Right Cessation
- 1987-05-20 ZA ZA873639A patent/ZA873639B/xx unknown
- 1987-05-20 IE IE131787A patent/IE60656B1/en not_active IP Right Cessation
- 1987-05-20 NZ NZ220380A patent/NZ220380A/xx unknown
- 1987-05-20 AU AU73239/87A patent/AU601426B2/en not_active Expired
- 1987-05-21 KR KR1019870005111A patent/KR950001020B1/ko not_active Expired - Lifetime
- 1987-05-21 US US07/052,371 patent/US4798827A/en not_active Expired - Lifetime
- 1987-05-21 DE DE8787401142T patent/DE3770048D1/de not_active Expired - Lifetime
- 1987-05-21 SU SU874202596A patent/SU1616520A3/ru active
- 1987-05-21 AT AT87401142T patent/ATE63563T1/de active
- 1987-05-21 DE DE2000175012 patent/DE10075012I2/de active Active
- 1987-05-21 ES ES198787401142T patent/ES2032457T3/es not_active Expired - Lifetime
- 1987-05-21 DK DK198702585A patent/DK172949B1/da active Protection Beyond IP Right Term
- 1987-05-21 EP EP87401142A patent/EP0248703B1/de not_active Expired - Lifetime
- 1987-05-21 CA CA000537562A patent/CA1271297A/fr not_active Expired - Lifetime
- 1987-05-21 FI FI872236A patent/FI84355C/fi not_active IP Right Cessation
- 1987-05-22 PT PT84934A patent/PT84934B/pt unknown
- 1987-05-22 JP JP62125613A patent/JP2558282B2/ja not_active Expired - Fee Related
-
1991
- 1991-05-20 GR GR90400906T patent/GR3002558T3/el unknown
-
1992
- 1992-06-26 MX MX9203577A patent/MX9203577A/es unknown
-
1993
- 1993-01-26 LV LV930070A patent/LV5268A3/xx unknown
- 1993-07-31 GE GEAP19931362A patent/GEP19960474B/en unknown
-
1996
- 1996-04-30 JP JP8130555A patent/JP2659531B2/ja not_active Expired - Fee Related
-
1997
- 1997-05-14 BR BR1101133-5A patent/BR1101133A/pt active IP Right Grant
-
2000
- 2000-06-16 NL NL300010C patent/NL300010I2/nl unknown
-
2001
- 2001-02-16 LU LU90732C patent/LU90732I2/en unknown
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