ES2132287T3 - Salmicinas, un procedimiento para su preparacion y su uso como producto farmaceutico. - Google Patents

Salmicinas, un procedimiento para su preparacion y su uso como producto farmaceutico.

Info

Publication number
ES2132287T3
ES2132287T3 ES94112382T ES94112382T ES2132287T3 ES 2132287 T3 ES2132287 T3 ES 2132287T3 ES 94112382 T ES94112382 T ES 94112382T ES 94112382 T ES94112382 T ES 94112382T ES 2132287 T3 ES2132287 T3 ES 2132287T3
Authority
ES
Spain
Prior art keywords
alkyl
salmicins
procedure
preparation
pharmaceutical product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94112382T
Other languages
English (en)
Inventor
Laszlo Dr Vertesy
Werner Dr Aretz
Hans-Wolfram Dr Fehlhaber
Bimal Naresh Dr Ganguli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP93710014A external-priority patent/EP0639583A1/en
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of ES2132287T3 publication Critical patent/ES2132287T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
    • C07H5/06—Aminosugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/02—Monosaccharides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/58—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound through only acyclic carbon atoms to a non-saccharide heterocyclic ring, e.g. bleomycin, phleomycin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

COMPUESTOS DE FORMULA (I), EN DONDE R REPRESENTA = NOH (A), = O (B); R" REPRESENTA FENILO O UN ALQUILO RAMIFICADO O NO RAMIFICADO CON 1 A 10 ATOMO DE CARBONO, R" REPRESENTA H, ALQUILO, HIDROXIALQUILO Y AMINOALQUILO, ASI COMO LOS EQUIVALENTES QUIMICOS Y LAS SALES DEL MISMO ACEPTABLES FISIOLOGICAMENTE. LAS SALMICINAS Y SUS DERIVADOS SE EMPLEAN COMO FARMACOS.
ES94112382T 1993-08-13 1994-08-08 Salmicinas, un procedimiento para su preparacion y su uso como producto farmaceutico. Expired - Lifetime ES2132287T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP93710014A EP0639583A1 (en) 1993-08-13 1993-08-13 Antibiotics, called Salmycin A, B and C, a process for their preparation and their use as a pharmaceutical
EP93115022 1993-09-17
EP93118511 1993-11-16

Publications (1)

Publication Number Publication Date
ES2132287T3 true ES2132287T3 (es) 1999-08-16

Family

ID=27235211

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94112382T Expired - Lifetime ES2132287T3 (es) 1993-08-13 1994-08-08 Salmicinas, un procedimiento para su preparacion y su uso como producto farmaceutico.

Country Status (8)

Country Link
US (1) US5475094A (es)
EP (1) EP0638587B1 (es)
JP (1) JPH0776595A (es)
AT (1) ATE181331T1 (es)
DE (1) DE69419083T2 (es)
DK (1) DK0638587T3 (es)
ES (1) ES2132287T3 (es)
GR (1) GR3030952T3 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000193648A (ja) * 1998-12-24 2000-07-14 Nomura Kagaku Kk 逆相液体クロマトグラフィー固定相の使用方法およびその固定相を備えた逆相液体クロマトグラフ装置

Also Published As

Publication number Publication date
GR3030952T3 (en) 1999-11-30
EP0638587A1 (en) 1995-02-15
US5475094A (en) 1995-12-12
JPH0776595A (ja) 1995-03-20
ATE181331T1 (de) 1999-07-15
EP0638587B1 (en) 1999-06-16
DE69419083D1 (de) 1999-07-22
DK0638587T3 (da) 1999-11-22
DE69419083T2 (de) 1999-11-25

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