ATE60933T1 - Fuer kaninchen-tnf kodierende dns, vektor mit dieser dns darin inseriert, mit diesem vektor transformierter wirt, kaninchen-tnf-polypeptid und verfahren zur herstellung desselben. - Google Patents
Fuer kaninchen-tnf kodierende dns, vektor mit dieser dns darin inseriert, mit diesem vektor transformierter wirt, kaninchen-tnf-polypeptid und verfahren zur herstellung desselben.Info
- Publication number
- ATE60933T1 ATE60933T1 AT84114325T AT84114325T ATE60933T1 AT E60933 T1 ATE60933 T1 AT E60933T1 AT 84114325 T AT84114325 T AT 84114325T AT 84114325 T AT84114325 T AT 84114325T AT E60933 T1 ATE60933 T1 AT E60933T1
- Authority
- AT
- Austria
- Prior art keywords
- vector
- rabbit tnf
- polypeptide
- tnf
- dna
- Prior art date
Links
- 241000283973 Oryctolagus cuniculus Species 0.000 title abstract 4
- 239000013598 vector Substances 0.000 title abstract 4
- 229920001184 polypeptide Polymers 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 108060008682 Tumor Necrosis Factor Proteins 0.000 abstract 3
- 102000003390 tumor necrosis factor Human genes 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/525—Tumour necrosis factor [TNF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58228790A JPH0695939B2 (ja) | 1983-12-02 | 1983-12-02 | ウサギ癌壊死因子をコ−ドするクロ−ン化ｄνａ |
| EP84114325A EP0146026B1 (de) | 1983-12-02 | 1984-11-27 | Für Kaninchen-TNF kodierende DNS, Vektor mit dieser DNS darin inseriert, mit diesem Vektor transformierter Wirt, Kaninchen-TNF-Polypeptid und Verfahren zur Herstellung desselben |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE60933T1 true ATE60933T1 (de) | 1991-03-15 |
Family
ID=16881888
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT84114325T ATE60933T1 (de) | 1983-12-02 | 1984-11-27 | Fuer kaninchen-tnf kodierende dns, vektor mit dieser dns darin inseriert, mit diesem vektor transformierter wirt, kaninchen-tnf-polypeptid und verfahren zur herstellung desselben. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5043271A (de) |
| EP (1) | EP0146026B1 (de) |
| JP (1) | JPH0695939B2 (de) |
| KR (1) | KR920009523B1 (de) |
| AT (1) | ATE60933T1 (de) |
| AU (1) | AU577810B2 (de) |
| DE (1) | DE3484125D1 (de) |
| DK (1) | DK572284A (de) |
| ES (2) | ES8604309A1 (de) |
| PH (1) | PH26947A (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1265444A (en) * | 1983-06-27 | 1990-02-06 | Lloyd J. Old | Effect of human tumor necrosis factor and human interferon on human cancer cells and methods |
| JPS60112718A (ja) * | 1983-11-21 | 1985-06-19 | Kyorin Pharmaceut Co Ltd | 抗腫瘍作用を示す蛋白性物質及びその製造方法 |
| JPS60139624A (ja) * | 1983-12-27 | 1985-07-24 | Dainippon Pharmaceut Co Ltd | 抗腫瘍作用を有する蛋白質 |
| US4879226A (en) * | 1984-04-06 | 1989-11-07 | Asahi Kasei Kogyo Kabushiki Kaisha | Novel human physiologically active polypeptide |
| GR851626B (de) * | 1984-07-05 | 1985-11-26 | Genentech Inc | |
| US5672347A (en) * | 1984-07-05 | 1997-09-30 | Genentech, Inc. | Tumor necrosis factor antagonists and their use |
| US6686455B1 (en) | 1984-07-05 | 2004-02-03 | Genentech, Inc. | Tumor necrosis factor |
| EP0216786B1 (de) * | 1984-12-21 | 1992-03-18 | Biogen, Inc. | Reinigung, herstellung und verwendung von tumor-nekrosisfaktoren |
| US5425940A (en) * | 1986-04-09 | 1995-06-20 | Cetus Oncology Corporation | Combination therapy using interleukin-2 and tumor necrosis factor |
| DE69029970T2 (de) | 1989-08-16 | 1997-06-19 | Chiron Corp | Zusammensetzungen zur hemmung der bildung von proteinhormon und deren verwendungen |
| US5998378A (en) * | 1989-08-16 | 1999-12-07 | Chiron Corporation | Compositions for the inhibition of TNF hormone formation and uses thereof |
| US6586222B1 (en) | 1989-08-16 | 2003-07-01 | Chiron Corporation | Recombinant PR-3 and compositions thereof |
| US5843693A (en) * | 1989-08-16 | 1998-12-01 | Chiron Corporation | Assay method for screening for inhibitors of proTNF conversion |
| WO1991017180A1 (en) * | 1990-04-27 | 1991-11-14 | Peptide Technology Ltd | Peptides derived from human tumour necrosis factor alpha and useful against intracellular malarial parasites |
| US5653974A (en) * | 1990-10-18 | 1997-08-05 | Board Of Regents,The University Of Texas System | Preparation and characterization of liposomal formulations of tumor necrosis factor |
| CA2185162A1 (en) | 1994-03-07 | 1995-09-14 | Robert F. Halenback (Deceased) | Compositions for the inhibition of tnf formation and uses thereof |
| EP1578799B8 (de) | 2002-12-02 | 2011-03-23 | Amgen Fremont Inc. | Gegen den tumor nekrose faktor gerichtete antikörper und deren verwendungen |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57140725A (en) * | 1981-12-28 | 1982-08-31 | Dainippon Pharmaceut Co Ltd | Physiologically active substance having carcinostatic action |
| JPS6019719A (ja) * | 1983-07-15 | 1985-01-31 | Asahi Chem Ind Co Ltd | 抗腫瘍活性を有する蛋白質 |
| DE3472793D1 (en) * | 1983-12-26 | 1988-08-25 | Asahi Chemical Ind | A novel physiologically active polypeptide |
| DE19975063I2 (de) * | 1984-03-06 | 2005-08-18 | Dainippon Pharmaceutical Co | DNS den menschlichen Tumornekrosisfaktor kodierendund das menschliche Tumornekronisfaktor-Polypepti d. |
| US4879226A (en) * | 1984-04-06 | 1989-11-07 | Asahi Kasei Kogyo Kabushiki Kaisha | Novel human physiologically active polypeptide |
-
1983
- 1983-12-02 JP JP58228790A patent/JPH0695939B2/ja not_active Expired - Lifetime
-
1984
- 1984-11-27 ES ES538000A patent/ES8604309A1/es not_active Expired
- 1984-11-27 AT AT84114325T patent/ATE60933T1/de not_active IP Right Cessation
- 1984-11-27 EP EP84114325A patent/EP0146026B1/de not_active Expired - Lifetime
- 1984-11-27 DE DE8484114325T patent/DE3484125D1/de not_active Expired - Lifetime
- 1984-11-27 KR KR1019840007423A patent/KR920009523B1/ko not_active Expired
- 1984-11-29 AU AU36014/84A patent/AU577810B2/en not_active Ceased
- 1984-11-29 PH PH31507A patent/PH26947A/en unknown
- 1984-11-30 US US06/677,680 patent/US5043271A/en not_active Expired - Fee Related
- 1984-11-30 DK DK572284A patent/DK572284A/da not_active Application Discontinuation
-
1985
- 1985-09-30 ES ES547436A patent/ES8605578A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| PH26947A (en) | 1992-12-03 |
| KR920009523B1 (ko) | 1992-10-17 |
| DK572284D0 (da) | 1984-11-30 |
| JPS60120990A (ja) | 1985-06-28 |
| KR850004272A (ko) | 1985-07-11 |
| EP0146026A2 (de) | 1985-06-26 |
| DK572284A (da) | 1985-06-03 |
| JPH0695939B2 (ja) | 1994-11-30 |
| ES538000A0 (es) | 1986-01-16 |
| EP0146026B1 (de) | 1991-02-20 |
| ES8604309A1 (es) | 1986-01-16 |
| DE3484125D1 (de) | 1991-03-28 |
| ES8605578A1 (es) | 1986-03-16 |
| EP0146026A3 (en) | 1987-05-20 |
| AU3601484A (en) | 1985-06-06 |
| ES547436A0 (es) | 1986-03-16 |
| AU577810B2 (en) | 1988-10-06 |
| US5043271A (en) | 1991-08-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |