ATE56703T1 - Substituierte azetidinone, diese enthaltende pharmazeutische zusammensetzungen und ihre verwendung zur herstellung von entzuendungshemmenden und antidegenerativen medikamenten. - Google Patents

Substituierte azetidinone, diese enthaltende pharmazeutische zusammensetzungen und ihre verwendung zur herstellung von entzuendungshemmenden und antidegenerativen medikamenten.

Info

Publication number
ATE56703T1
ATE56703T1 AT86400751T AT86400751T ATE56703T1 AT E56703 T1 ATE56703 T1 AT E56703T1 AT 86400751 T AT86400751 T AT 86400751T AT 86400751 T AT86400751 T AT 86400751T AT E56703 T1 ATE56703 T1 AT E56703T1
Authority
AT
Austria
Prior art keywords
inflammatory
antidegenerative
medications
manufacture
pharmaceutical compositions
Prior art date
Application number
AT86400751T
Other languages
English (en)
Inventor
K Shah Shrenik
Raymond A Firestone
Peter L Barker
William Hagmann
James B Doherty
Conrad P Dorn
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of ATE56703T1 publication Critical patent/ATE56703T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT86400751T 1985-04-10 1986-04-08 Substituierte azetidinone, diese enthaltende pharmazeutische zusammensetzungen und ihre verwendung zur herstellung von entzuendungshemmenden und antidegenerativen medikamenten. ATE56703T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/721,811 US4680391A (en) 1983-12-01 1985-04-10 Substituted azetidinones as anti-inflammatory and antidegenerative agents
EP86400751A EP0199630B1 (de) 1985-04-10 1986-04-08 Substituierte Azetidinone, diese enthaltende pharmazeutische Zusammensetzungen und ihre Verwendung zur Herstellung von entzündungshemmenden und antidegenerativen Medikamenten

Publications (1)

Publication Number Publication Date
ATE56703T1 true ATE56703T1 (de) 1990-10-15

Family

ID=24899403

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86400751T ATE56703T1 (de) 1985-04-10 1986-04-08 Substituierte azetidinone, diese enthaltende pharmazeutische zusammensetzungen und ihre verwendung zur herstellung von entzuendungshemmenden und antidegenerativen medikamenten.

Country Status (8)

Country Link
US (1) US4680391A (de)
EP (1) EP0199630B1 (de)
JP (1) JPS61289074A (de)
AT (1) ATE56703T1 (de)
CA (1) CA1286304C (de)
DE (1) DE3674237D1 (de)
DK (1) DK159386A (de)
ES (1) ES8801785A1 (de)

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US5175283A (en) * 1990-06-04 1992-12-29 Bristol-Myers Squibb Company Azetidin-2-one derivatives as serine protease inhibitors
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US6335362B1 (en) 1991-09-23 2002-01-01 Florida State University Taxanes having an alkyl substituted side-chain and pharmaceutical compositions containing them
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Also Published As

Publication number Publication date
DE3674237D1 (de) 1990-10-25
ES8801785A1 (es) 1988-02-16
US4680391A (en) 1987-07-14
DK159386A (da) 1986-10-11
JPS61289074A (ja) 1986-12-19
ES553821A0 (es) 1988-02-16
EP0199630B1 (de) 1990-09-19
CA1286304C (en) 1991-07-16
EP0199630A1 (de) 1986-10-29
DK159386D0 (da) 1986-04-09

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