DE3577986D1 - Substituierte azetidinonverbindungen, deren herstellung und ihre enthaltenden arzneimittel. - Google Patents

Substituierte azetidinonverbindungen, deren herstellung und ihre enthaltenden arzneimittel.

Info

Publication number
DE3577986D1
DE3577986D1 DE8585304532T DE3577986T DE3577986D1 DE 3577986 D1 DE3577986 D1 DE 3577986D1 DE 8585304532 T DE8585304532 T DE 8585304532T DE 3577986 T DE3577986 T DE 3577986T DE 3577986 D1 DE3577986 D1 DE 3577986D1
Authority
DE
Germany
Prior art keywords
production
medicinal products
containing medicinal
substituted azetidinone
azetidinone compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8585304532T
Other languages
English (en)
Inventor
Toshinari Tamura
Makoto Yoshida
Shin-Ichi Tsukamoto
Hidenori Iwamoto
Minoru Yamamoto
Soichi Kagami
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP59129220A external-priority patent/JPS6110578A/ja
Priority claimed from JP14817384A external-priority patent/JPS6127960A/ja
Priority claimed from JP59199827A external-priority patent/JPS6178785A/ja
Priority claimed from JP59199828A external-priority patent/JPS6178786A/ja
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE3577986D1 publication Critical patent/DE3577986D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8585304532T 1984-06-25 1985-06-25 Substituierte azetidinonverbindungen, deren herstellung und ihre enthaltenden arzneimittel. Expired - Fee Related DE3577986D1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP59129220A JPS6110578A (ja) 1984-06-25 1984-06-25 １−および／または３−置換−４−オキソ−２−アゼチジニルカルボニル誘導体およびその製造法
JP14817384A JPS6127960A (ja) 1984-07-17 1984-07-17 α−（２−オキソ−１−アゼチジニル）酢酸誘導体及びその製法
JP59199827A JPS6178785A (ja) 1984-09-25 1984-09-25 新規４−オキソ−２−アゼチジンカルボン酸誘導体
JP59199828A JPS6178786A (ja) 1984-09-25 1984-09-25 新規４−オキソ−２−アゼチジンカルボン酸誘導体

Publications (1)

Publication Number Publication Date
DE3577986D1 true DE3577986D1 (de) 1990-07-05

Family

ID=27471434

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585304532T Expired - Fee Related DE3577986D1 (de) 1984-06-25 1985-06-25 Substituierte azetidinonverbindungen, deren herstellung und ihre enthaltenden arzneimittel.

Country Status (4)

Country Link
US (1) US4719207A (de)
EP (1) EP0171159B1 (de)
CA (1) CA1270097A (de)
DE (1) DE3577986D1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA868957B (en) * 1985-12-06 1987-07-29 Yamanouchi Pharma Co Ltd Crystals of nalpha-(((s)-4-oxo-2-azetidinyl)carbonyl)-l-histidyl-l-prolinamide and process for producing the crystals
US5312914A (en) * 1987-02-17 1994-05-17 Ciba-Geigy Corp Process for the manufacture of 4-acetoxy-3-hydroxyethyl-azetidinone
EP0279781A3 (de) * 1987-02-17 1989-07-26 Ciba-Geigy Ag Verfahren zur Herstellung von 4-Acetoxy-3-hydroxyethyl-azetidinon
US5686420A (en) * 1987-06-05 1997-11-11 Georgetown University Thyrotropin-releasing hormone analogs and method of use
US5151497A (en) * 1989-02-21 1992-09-29 Japan Tobacco Inc. Histidyl peptide derivatives
CA2010312C (en) * 1989-02-21 1998-05-12 Akihiro Yasuda Peptide derivatives and their pharmaceutical use
EP0473993B1 (de) * 1990-08-17 1996-04-17 Japan Tobacco Inc. Neue Peptidderivate und deren pharmazeutischer Gebrauch
GB9515411D0 (en) * 1995-07-27 1995-09-27 Pharmacia Spa N-(4-substituted-benzyl)-2-aminolactam derivatives
EP1545479B1 (de) * 2002-07-30 2010-10-27 Karykion Inc. Zusammensetzungen aus ezetimib und verfahren zur behandlung von mit cholesterin zusammenhängenden gutartigen und bösartigen tumoren
US7462595B2 (en) * 2004-09-17 2008-12-09 Prange Jr Arthur Jergen Methods for treating cancer-related fatigue
KR20080033250A (ko) * 2005-06-10 2008-04-16 플로리다 스테이트 유니버시티 리서치 파운데이션, 인크 β-락탐의 거울상이성질체 혼합물의 분리

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0001174B1 (de) * 1977-09-06 1981-08-12 NYEGAARD & CO. A/S Ein Peptid und dessen Salze, Verfahren zur Herstellung derselben und diese Verbindungen enthaltende Zusammensetzungen
HU180926B (en) * 1979-06-28 1983-05-30 Richter Gedeon Vegyeszet Process for preparing trh analogues,tripeptide amides infectives on the central nerve sysrhem
CA1256650A (en) * 1983-03-25 1989-06-27 Toshinari Tamura Process of producing 2-azetidinone-4-substituted compounds, and medicaments containing the compounds

Also Published As

Publication number Publication date
EP0171159B1 (de) 1990-05-30
EP0171159A1 (de) 1986-02-12
US4719207A (en) 1988-01-12
CA1270097A (en) 1990-06-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee