ATE555201T1 - Verwendung von sirna zur abschaffung der expression von eif-5a1 in der behandlung von glaukoma - Google Patents
Verwendung von sirna zur abschaffung der expression von eif-5a1 in der behandlung von glaukomaInfo
- Publication number
- ATE555201T1 ATE555201T1 AT04717933T AT04717933T ATE555201T1 AT E555201 T1 ATE555201 T1 AT E555201T1 AT 04717933 T AT04717933 T AT 04717933T AT 04717933 T AT04717933 T AT 04717933T AT E555201 T1 ATE555201 T1 AT E555201T1
- Authority
- AT
- Austria
- Prior art keywords
- factor
- apoptosis
- expression
- eif
- abolitate
- Prior art date
Links
- 101150061075 EIF5A1 gene Proteins 0.000 title 1
- 208000010412 Glaucoma Diseases 0.000 title 1
- 230000006907 apoptotic process Effects 0.000 abstract 4
- 230000002401 inhibitory effect Effects 0.000 abstract 3
- 102000016614 Autophagy-Related Protein 5 Human genes 0.000 abstract 1
- 108010092776 Autophagy-Related Protein 5 Proteins 0.000 abstract 1
- 102000004127 Cytokines Human genes 0.000 abstract 1
- 108090000695 Cytokines Proteins 0.000 abstract 1
- 108010074105 Factor Va Proteins 0.000 abstract 1
- 102000005877 Peptide Initiation Factors Human genes 0.000 abstract 1
- 108010044843 Peptide Initiation Factors Proteins 0.000 abstract 1
- 108020004459 Small interfering RNA Proteins 0.000 abstract 1
- 230000000692 anti-sense effect Effects 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000000770 proinflammatory effect Effects 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45167703P | 2003-03-05 | 2003-03-05 | |
| US10/383,614 US7381708B2 (en) | 2001-07-23 | 2003-03-10 | Suppression of eIF5A1 expression by the use of antisense oligonucleotides for the prevention of retinal cell death in the glaucomatous eye |
| US47619403P | 2003-06-06 | 2003-06-06 | |
| US50473103P | 2003-09-22 | 2003-09-22 | |
| US52824903P | 2003-12-10 | 2003-12-10 | |
| PCT/US2004/006598 WO2004078940A2 (en) | 2003-03-05 | 2004-03-05 | USE OF ANTISENSE OLIGONUCLEOTIDES OR siRNA TO SUPPRESS EXPRESSION OF eIF-5A1 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE555201T1 true ATE555201T1 (de) | 2012-05-15 |
Family
ID=43635484
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04717933T ATE555201T1 (de) | 2003-03-05 | 2004-03-05 | Verwendung von sirna zur abschaffung der expression von eif-5a1 in der behandlung von glaukoma |
Country Status (3)
| Country | Link |
|---|---|
| JP (1) | JP5566250B2 (de) |
| CN (1) | CN101014708B (de) |
| AT (1) | ATE555201T1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2427553A4 (de) * | 2009-05-06 | 2012-11-07 | Opko Curna Llc | Behandlung von lipidtransport- und stoffwechselgenbedingten erkrankungen mittels hemmung des natürlichen antisense-transkripts gegen ein lipidtransport- und stoffwechselgen |
| JP7729583B2 (ja) * | 2021-05-18 | 2025-08-26 | 学校法人順天堂 | 炎症性腸疾患の予防又は治療薬 |
| CN114231551B (zh) * | 2021-12-24 | 2023-09-29 | 云南大学 | 蛋白在促进昆虫淋巴细胞凋亡和/或防治害虫中的应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7166467B2 (en) * | 2001-07-23 | 2007-01-23 | Senesco Technologies, Inc. | Nucleic acids, polypeptides, compositions, and methods for modulating apoptosis |
| EP1601767B1 (de) * | 2003-03-05 | 2012-04-25 | Senesco Technologies, Inc. | Verwendung von sirna zur abschaffung der expression von eif-5a1 in der behandlung von glaukoma |
-
2004
- 2004-03-05 AT AT04717933T patent/ATE555201T1/de active
- 2004-03-05 CN CN200480012061.4A patent/CN101014708B/zh not_active Expired - Fee Related
-
2010
- 2010-10-08 JP JP2010229103A patent/JP5566250B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN101014708B (zh) | 2011-11-02 |
| JP2011026343A (ja) | 2011-02-10 |
| CN101014708A (zh) | 2007-08-08 |
| JP5566250B2 (ja) | 2014-08-06 |
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