ATE551432T1 - Bei manisch-depressiver erkrankung und/oder schwerer depressiver erkrankung unterschiedlich exprimierte gene und wege - Google Patents
Bei manisch-depressiver erkrankung und/oder schwerer depressiver erkrankung unterschiedlich exprimierte gene und wegeInfo
- Publication number
- ATE551432T1 ATE551432T1 AT05762518T AT05762518T ATE551432T1 AT E551432 T1 ATE551432 T1 AT E551432T1 AT 05762518 T AT05762518 T AT 05762518T AT 05762518 T AT05762518 T AT 05762518T AT E551432 T1 ATE551432 T1 AT E551432T1
- Authority
- AT
- Austria
- Prior art keywords
- depressive disease
- manic
- genes
- expressed differently
- disease
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/713—Double-stranded nucleic acids or oligonucleotides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1825—Fibroblast growth factor [FGF]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering N.A.
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/172—Haplotypes
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/30—Psychoses; Psychiatry
- G01N2800/304—Mood disorders, e.g. bipolar, depression
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US58199804P | 2004-06-21 | 2004-06-21 | |
US62125204P | 2004-10-22 | 2004-10-22 | |
US66729605P | 2005-03-31 | 2005-03-31 | |
PCT/US2005/022111 WO2006002262A2 (en) | 2004-06-21 | 2005-06-21 | Genes and pathways differentially expressed in bipolar disorder and/or major depressive disorder |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE551432T1 true ATE551432T1 (de) | 2012-04-15 |
Family
ID=35782328
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT05762518T ATE551432T1 (de) | 2004-06-21 | 2005-06-21 | Bei manisch-depressiver erkrankung und/oder schwerer depressiver erkrankung unterschiedlich exprimierte gene und wege |
Country Status (8)
Country | Link |
---|---|
US (3) | US8415298B2 (de) |
EP (2) | EP2453024B1 (de) |
AT (1) | ATE551432T1 (de) |
AU (1) | AU2005258161B2 (de) |
CA (1) | CA2571243A1 (de) |
DK (2) | DK2453024T3 (de) |
ES (1) | ES2660765T3 (de) |
WO (1) | WO2006002262A2 (de) |
Families Citing this family (28)
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AU2003291720A1 (en) * | 2002-11-01 | 2004-06-18 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for diagnosing and treating mood disorders |
EP2453024B1 (de) | 2004-06-21 | 2017-12-06 | The Board of Trustees of The Leland Stanford Junior University | Differenziell exprimierte Gene und Leitungsbahnen bei bipolarer Störung und/oder schwerer depressiver Erkrankung |
AU2006315562C1 (en) | 2005-11-12 | 2013-10-03 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for treating depression using NCAM peptide mimetics |
WO2007136797A1 (en) * | 2006-05-18 | 2007-11-29 | The Mclean Hospital Corporation | Methods for diagnosis and prognosis of psychotic disorders |
WO2008124428A1 (en) * | 2007-04-03 | 2008-10-16 | Indiana University Research And Technology Corporation | Blood biomarkers for mood disorders |
US20100248230A1 (en) * | 2007-04-14 | 2010-09-30 | Schlaak Joerg Friedrich | Novel medical diagnostic method and therapy in the context of interfreon-stimulated genes that induce depression |
WO2008144371A1 (en) * | 2007-05-16 | 2008-11-27 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for diagnosing suicidal tendencies |
WO2009011911A2 (en) * | 2007-07-18 | 2009-01-22 | The Johns Hopkins University | Methods of detecting prostate cancer |
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CA2704428C (en) * | 2007-11-02 | 2018-04-17 | The Board Of Trustees Of The Leland Stanford Junior University | Fgf9-related methods for treating anxiety |
EP2570498A3 (de) * | 2008-01-02 | 2013-03-27 | Suregene Llc | Genetische Marker für Geisteskrankheiten |
FR2929292A1 (fr) * | 2008-03-28 | 2009-10-02 | Exonhit Therapeutics S A Sa | Procede et methodes de diagnostic de la maladie d'alzheimer |
GB0808832D0 (en) * | 2008-05-15 | 2008-06-18 | Ge Healthcare Ltd | Biomarkers for depression |
GB0808834D0 (en) * | 2008-05-15 | 2008-06-18 | Ge Healthcare Ltd | Biomarkers for depression |
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CA2728171A1 (en) * | 2008-08-27 | 2010-03-04 | H. Lundbeck A/S | System and methods for measuring biomarker profiles |
CA2743542A1 (en) * | 2008-11-12 | 2010-05-20 | University Of Utah Research Foundation | Autism associated genetic markers |
JP2012511895A (ja) * | 2008-11-14 | 2012-05-31 | ザ チルドレンズ ホスピタル オブ フィラデルフィア | ヒト認知の原因となる遺伝子変異体及び診断標的及び治療標的としてのそれらを使用する方法 |
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GB201204816D0 (en) * | 2012-03-19 | 2012-05-02 | Brainco Biopharma S L | Transgenic animal model of mood disorders |
WO2014133707A1 (en) * | 2013-03-01 | 2014-09-04 | Psychnostics, Llc | Genes expressed in mental illness and mood disorders |
US11235020B2 (en) * | 2013-03-13 | 2022-02-01 | Abraham Palmer | Methods and compositions for inhibiting glyoxalase 1 (GLO1) |
US20160209428A1 (en) * | 2013-08-21 | 2016-07-21 | The Regents Of The University Of California | Diagnostic and predictive metabolite patterns for disorders affecting the brain and nervous system |
WO2015129324A1 (ja) * | 2014-02-26 | 2015-09-03 | 国立大学法人徳島大学 | 精神疾患マーカーおよびその用途 |
CN109022486B (zh) * | 2018-09-20 | 2021-09-07 | 河北医科大学第二医院 | 一种癫痫动物模型的构建方法 |
EP3819387A1 (de) * | 2019-11-08 | 2021-05-12 | Alcediag | Differentialdiagnose von bipolarer störung und unipolarer depression durch blut-rna-bearbeitungsbiomarker |
CN111621525B (zh) * | 2020-06-18 | 2021-04-23 | 中赛干细胞基因工程有限公司 | Stx1b基因在促进人脂肪间充质干细胞生长和分化中的用途 |
CN116904578B (zh) * | 2023-07-21 | 2024-03-15 | 武汉市精神卫生中心 | 线粒体差异化表达特征基因在制备重度抑郁症诊断剂中的应用 |
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US20040152107A1 (en) | 2002-09-18 | 2004-08-05 | C. Anthony Altar | Gene signature of electroshock therapy and methods of use |
AU2003291720A1 (en) | 2002-11-01 | 2004-06-18 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for diagnosing and treating mood disorders |
EP1560933A4 (de) | 2002-11-14 | 2007-11-21 | Wyeth Corp | Verfahren und zusammensetzungen zur behandlung neurologischer erkrankungen |
CA2451267A1 (en) | 2002-12-13 | 2004-06-13 | Warner-Lambert Company Llc | Pharmaceutical uses for alpha2delta ligands |
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JP2005312435A (ja) | 2004-03-29 | 2005-11-10 | Kazuhito Rokutan | うつ病の評価方法 |
EP2453024B1 (de) | 2004-06-21 | 2017-12-06 | The Board of Trustees of The Leland Stanford Junior University | Differenziell exprimierte Gene und Leitungsbahnen bei bipolarer Störung und/oder schwerer depressiver Erkrankung |
AU2006315562C1 (en) | 2005-11-12 | 2013-10-03 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for treating depression using NCAM peptide mimetics |
CA2704428C (en) | 2007-11-02 | 2018-04-17 | The Board Of Trustees Of The Leland Stanford Junior University | Fgf9-related methods for treating anxiety |
JO3421B1 (ar) | 2011-06-20 | 2019-10-20 | H Lundbeck As | طريقة لإعطاء 1-((1ار.3س)-6-كلورو-3-فينيل-اندان-1-ايل)-1.2.2-ترايميثيل- بيبيرازين واملاجها لمعالجة انفصام الشخصية |
-
2005
- 2005-06-21 EP EP11175854.6A patent/EP2453024B1/de active Active
- 2005-06-21 WO PCT/US2005/022111 patent/WO2006002262A2/en active Application Filing
- 2005-06-21 DK DK11175854.6T patent/DK2453024T3/en active
- 2005-06-21 US US11/158,530 patent/US8415298B2/en active Active
- 2005-06-21 AU AU2005258161A patent/AU2005258161B2/en active Active
- 2005-06-21 EP EP05762518A patent/EP1766077B1/de active Active
- 2005-06-21 AT AT05762518T patent/ATE551432T1/de active
- 2005-06-21 ES ES11175854.6T patent/ES2660765T3/es active Active
- 2005-06-21 DK DK05762518.8T patent/DK1766077T3/da active
- 2005-06-21 CA CA002571243A patent/CA2571243A1/en not_active Abandoned
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2013
- 2013-02-25 US US13/776,647 patent/US9486499B2/en active Active
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2016
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Also Published As
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EP2453024A3 (de) | 2012-08-15 |
AU2005258161B2 (en) | 2011-05-26 |
EP2453024A2 (de) | 2012-05-16 |
WO2006002262A3 (en) | 2007-06-14 |
EP1766077A2 (de) | 2007-03-28 |
US9486499B2 (en) | 2016-11-08 |
WO2006002262A2 (en) | 2006-01-05 |
US20140073568A1 (en) | 2014-03-13 |
ES2660765T3 (es) | 2018-03-26 |
CA2571243A1 (en) | 2006-01-05 |
US9957568B2 (en) | 2018-05-01 |
EP2453024B1 (de) | 2017-12-06 |
US20170211144A1 (en) | 2017-07-27 |
DK2453024T3 (en) | 2018-02-12 |
US8415298B2 (en) | 2013-04-09 |
DK1766077T3 (da) | 2012-07-16 |
EP1766077B1 (de) | 2012-03-28 |
US20060051786A1 (en) | 2006-03-09 |
EP1766077A4 (de) | 2008-02-13 |
AU2005258161A1 (en) | 2006-01-05 |
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