ATE547403T1 - Fluoreszente regulatoren der rassf1a-expression und der proliferation humaner krebszellen - Google Patents

Fluoreszente regulatoren der rassf1a-expression und der proliferation humaner krebszellen

Info

Publication number
ATE547403T1
ATE547403T1 AT09789145T AT09789145T ATE547403T1 AT E547403 T1 ATE547403 T1 AT E547403T1 AT 09789145 T AT09789145 T AT 09789145T AT 09789145 T AT09789145 T AT 09789145T AT E547403 T1 ATE547403 T1 AT E547403T1
Authority
AT
Austria
Prior art keywords
group
heterogroup
rassf1a
expression
aryl group
Prior art date
Application number
AT09789145T
Other languages
German (de)
English (en)
Inventor
Milton Brown
Kathryn Sheikh
Mikell Paige
Partha Banerjee
Shankar Jagadeesh
Original Assignee
Univ Georgetown
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Georgetown filed Critical Univ Georgetown
Application granted granted Critical
Publication of ATE547403T1 publication Critical patent/ATE547403T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
  • Electroluminescent Light Sources (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT09789145T 2008-08-15 2009-08-14 Fluoreszente regulatoren der rassf1a-expression und der proliferation humaner krebszellen ATE547403T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18905908P 2008-08-15 2008-08-15
PCT/US2009/004681 WO2010019271A1 (en) 2008-08-15 2009-08-14 Fluorescent regulators of rassf1a expression and human cancer cell proliferation

Publications (1)

Publication Number Publication Date
ATE547403T1 true ATE547403T1 (de) 2012-03-15

Family

ID=41279343

Family Applications (1)

Application Number Title Priority Date Filing Date
AT09789145T ATE547403T1 (de) 2008-08-15 2009-08-14 Fluoreszente regulatoren der rassf1a-expression und der proliferation humaner krebszellen

Country Status (9)

Country Link
US (1) US10457639B2 (https=)
EP (2) EP2323982B1 (https=)
JP (2) JP2012500197A (https=)
CN (1) CN102186820B (https=)
AT (1) ATE547403T1 (https=)
AU (1) AU2009282451B2 (https=)
BR (1) BRPI0917411A2 (https=)
CA (1) CA2734225A1 (https=)
WO (1) WO2010019271A1 (https=)

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Also Published As

Publication number Publication date
WO2010019271A1 (en) 2010-02-18
BRPI0917411A2 (pt) 2015-12-01
EP2323982B1 (en) 2012-02-29
JP2012500197A (ja) 2012-01-05
CN102186820A (zh) 2011-09-14
JP2014148545A (ja) 2014-08-21
EP2484666A1 (en) 2012-08-08
HK1158206A1 (en) 2012-07-13
AU2009282451A1 (en) 2010-02-18
CA2734225A1 (en) 2010-02-18
US20110152339A1 (en) 2011-06-23
EP2323982A1 (en) 2011-05-25
US10457639B2 (en) 2019-10-29
WO2010019271A8 (en) 2011-03-31
AU2009282451B2 (en) 2014-02-13
CN102186820B (zh) 2013-08-28

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