ATE546518T1 - S-adenosylmethionin-synthetase-mutanten, diese codierende dnas und verwendungen der mutanten - Google Patents

S-adenosylmethionin-synthetase-mutanten, diese codierende dnas und verwendungen der mutanten

Info

Publication number
ATE546518T1
ATE546518T1 AT07800820T AT07800820T ATE546518T1 AT E546518 T1 ATE546518 T1 AT E546518T1 AT 07800820 T AT07800820 T AT 07800820T AT 07800820 T AT07800820 T AT 07800820T AT E546518 T1 ATE546518 T1 AT E546518T1
Authority
AT
Austria
Prior art keywords
mutants
adenosylmethionine synthetase
adenosylmethionine
coding dnas
sequence
Prior art date
Application number
AT07800820T
Other languages
English (en)
Inventor
Rongzhao Fu
Tianzuo Zhang
Jun Wang
Original Assignee
Bioright Worldwide Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioright Worldwide Co Ltd filed Critical Bioright Worldwide Co Ltd
Application granted granted Critical
Publication of ATE546518T1 publication Critical patent/ATE546518T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y205/00—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5)
    • C12Y205/01—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5) transferring alkyl or aryl groups, other than methyl groups (2.5.1)
    • C12Y205/01006—Methionine adenosyltransferase (2.5.1.6), i.e. adenosylmethionine synthetase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT07800820T 2006-08-31 2007-08-30 S-adenosylmethionin-synthetase-mutanten, diese codierende dnas und verwendungen der mutanten ATE546518T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2006101276368A CN101134948B (zh) 2006-08-31 2006-08-31 S-腺苷甲硫氨酸合成酶突变体、编码该突变体的dna以及突变体的应用
PCT/CN2007/002603 WO2008034338A1 (fr) 2006-08-31 2007-08-30 Mutants de la s-adénosylméthionine synthétase, les adn les codant et les utilisations de ces mutants

Publications (1)

Publication Number Publication Date
ATE546518T1 true ATE546518T1 (de) 2012-03-15

Family

ID=39159272

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07800820T ATE546518T1 (de) 2006-08-31 2007-08-30 S-adenosylmethionin-synthetase-mutanten, diese codierende dnas und verwendungen der mutanten

Country Status (5)

Country Link
US (1) US7858351B2 (de)
EP (1) EP2071022B1 (de)
CN (1) CN101134948B (de)
AT (1) ATE546518T1 (de)
WO (1) WO2008034338A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2871234A1 (de) 2013-11-06 2015-05-13 Leibniz-Institut für Pflanzenbiochemie (IPB) S-Adenosylmethionin (SAM) Synthesevarianten zur Synthese von künstlichen Kofaktoren
CN106032520A (zh) 2015-03-13 2016-10-19 基因港(香港)生物科技有限公司 固定化反应装置及利用固定化技术进行反应的方法
CN110144336B (zh) * 2019-05-23 2020-09-04 浙江大学 一种s-腺苷甲硫氨酸合成酶突变体及其制备方法
CN111235084B (zh) * 2020-04-01 2021-08-20 湖南福来格生物技术有限公司 重组大肠杆菌工程菌及利用其制备s-腺苷甲硫氨酸的方法
CN111235126B (zh) * 2020-04-01 2021-08-20 湖南福来格生物技术有限公司 一种s-腺苷甲硫氨酸合成酶突变体及利用其的制备方法
CN117535263A (zh) * 2022-11-11 2024-02-09 山东理工大学 一种基于297位点的s-腺苷蛋氨酸合成酶突变体及其应用
CN116355875B (zh) * 2023-05-08 2023-08-01 北京量维生物科技研究院有限公司 甲硫氨酸腺苷基转移酶突变体及其在生产s-腺苷甲硫氨酸中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1379102A (zh) * 2002-02-01 2002-11-13 杭州华大基因研发中心 耐高温s－腺苷甲硫氨酸合成酶基因及其编码的多肽和制备方法
CN1217002C (zh) 2003-06-12 2005-08-31 北京凯因生物技术有限公司 酶催化生产腺苷甲硫氨酸的方法
WO2005111202A1 (en) * 2004-05-12 2005-11-24 Metabolic Explorer Recombinant enzyme with altered feedback sensitivity
DE102004055414A1 (de) * 2004-11-17 2006-05-24 Degussa Ag Allele des metK-Gens aus coryneformen Bakterien

Also Published As

Publication number Publication date
EP2071022A1 (de) 2009-06-17
CN101134948A (zh) 2008-03-05
US20090203080A1 (en) 2009-08-13
EP2071022A4 (de) 2010-09-22
EP2071022B1 (de) 2012-02-22
CN101134948B (zh) 2011-12-07
WO2008034338A1 (fr) 2008-03-27
US7858351B2 (en) 2010-12-28

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