BR0113411A - Processo para a produção do composto de biopterina - Google Patents

Processo para a produção do composto de biopterina

Info

Publication number
BR0113411A
BR0113411A BR0113411-6A BR0113411A BR0113411A BR 0113411 A BR0113411 A BR 0113411A BR 0113411 A BR0113411 A BR 0113411A BR 0113411 A BR0113411 A BR 0113411A
Authority
BR
Brazil
Prior art keywords
production
biopterin compound
present
biopterin
compound
Prior art date
Application number
BR0113411-6A
Other languages
English (en)
Inventor
Yabuta Masayuki
Furukawa Kazuaki
Miyamoto Nobue
Yamamoto Katsuhiko
Ohsuye Kazuhiro
Original Assignee
Daiichi Suntory Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Suntory Pharma Co Ltd filed Critical Daiichi Suntory Pharma Co Ltd
Publication of BR0113411A publication Critical patent/BR0113411A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/182—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

"PROCESSO PARA PRODUçãO DO COMPOSTO DE BIOPTERINA". A presente invenção proporciona uma célula transformada que é transformada por pelo menos um gene de enzimas que participam na biosíntese de tetraidrobiopterina e a um processo para produção de um composto de biopterina usando a mesma. De acordo com a presente invenção, o composto de biopterina pode ser produzido em grandes quantidades, em uma escala vantajosamente industrial, a partir de materiais menos dispendiosos.
BR0113411-6A 2000-08-31 2001-08-28 Processo para a produção do composto de biopterina BR0113411A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000262973 2000-08-31
PCT/JP2001/007395 WO2002018587A1 (fr) 2000-08-31 2001-08-28 Procede de production de biopterines

Publications (1)

Publication Number Publication Date
BR0113411A true BR0113411A (pt) 2004-01-06

Family

ID=18750574

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0113411-6A BR0113411A (pt) 2000-08-31 2001-08-28 Processo para a produção do composto de biopterina

Country Status (13)

Country Link
US (2) US20040014167A1 (pt)
EP (1) EP1314782B1 (pt)
JP (1) JP4817590B2 (pt)
KR (1) KR100916163B1 (pt)
CN (1) CN1247778C (pt)
AT (1) ATE426021T1 (pt)
AU (1) AU2001280215B9 (pt)
BR (1) BR0113411A (pt)
CA (1) CA2420374A1 (pt)
DE (1) DE60138029D1 (pt)
ES (1) ES2320531T3 (pt)
IL (2) IL154530A0 (pt)
WO (1) WO2002018587A1 (pt)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7442372B2 (en) 2003-08-29 2008-10-28 Biomarin Pharmaceutical Inc. Delivery of therapeutic compounds to the brain and other tissues
EP1708690B1 (en) * 2003-11-17 2016-07-20 BioMarin Pharmaceutical Inc. Treatment of phenylketonuria with bh4
CN101132776A (zh) 2004-11-17 2008-02-27 生物马林药物股份有限公司 稳定的四氢生物喋呤片剂制剂
JPWO2006085535A1 (ja) * 2005-02-09 2008-06-26 株式会社カネカ テトラヒドロビオプテリン生合成酵素を用いたビオプテリン類の製造方法
HUE058030T2 (hu) 2007-04-11 2022-06-28 Biomarin Pharm Inc Tetrahidrobiopterin emelt fenilalanin szintekkel összefüggõ állapotok kezelésében történõ alkalmazásra
JP5084481B2 (ja) * 2007-12-10 2012-11-28 花王株式会社 血圧調節剤のスクリーニング方法及び評価方法
AU2008347005B2 (en) 2008-01-03 2013-10-03 Biomarin Pharmaceutical Inc. Pterin analog for treating BH4 responsive condition
MX2010007452A (es) 2008-01-07 2010-08-18 Biomarin Pharm Inc Metodo para sintetizar tetrahidrobiopterin.
WO2012135389A2 (en) * 2011-03-28 2012-10-04 The Regents Of The University Of California Host cells and methods for oxidizing aromatic amino acids
KR101229912B1 (ko) * 2011-04-06 2013-02-05 강원대학교산학협력단 재조합 대장균을 이용한 세피아프테린의 제조방법
US9216178B2 (en) 2011-11-02 2015-12-22 Biomarin Pharmaceutical Inc. Dry blend formulation of tetrahydrobiopterin
CN102516246B (zh) * 2011-11-30 2014-08-06 安徽农业大学 一种从蚕体中提取纯化高纯度墨蝶呤的方法
EP2820122A1 (en) * 2012-02-29 2015-01-07 Danmarks Tekniske Universitet Microorganisms for the production of 5-hydroxytryptophan
WO2013127915A1 (en) * 2012-02-29 2013-09-06 Danmarks Tekniske Universitet Microorganisms for the production of melatonin
CN102925476B (zh) * 2012-11-15 2014-12-03 中国科学院上海巴斯德研究所 酵母中自组装的具有免疫原性的肠道病毒病毒样颗粒的制备方法及其应用
CN103952367B (zh) * 2013-04-16 2016-06-01 中国人民解放军军事医学科学院基础医学研究所 一种发酵培养基及利用其生产黑色素瘤治疗性质粒DNA疫苗pSVK-CAVA的方法
WO2015032911A1 (en) * 2013-09-05 2015-03-12 Danmarks Tekniske Universitet Microorganisms for efficient production of melatonin and related compounds
EP3143153A4 (en) * 2014-05-16 2018-01-03 The University Of Georgia Research Foundation, Inc. Microbial approach for the production of 5-hydroxytryptophan
US11085060B2 (en) * 2015-01-02 2021-08-10 Georgia Tech Research Corporation Pterin-dependent biocatalysts and uses thereof
WO2017167866A1 (en) 2016-03-31 2017-10-05 Danmarks Tekniske Universitet Optimized microbial cells for production of melatonin and other compounds
US10851365B2 (en) 2016-03-31 2020-12-01 Danmarks Tekniske Universitet Optimized microbial cells for production of melatonin and other compounds
EP3464572B1 (en) 2016-05-24 2023-07-26 Danmarks Tekniske Universitet Variants of acetylserotonin o-methyltransferase and uses thereof
US10767203B2 (en) 2016-12-13 2020-09-08 Danmarks Tekniske Universitet Arylalkylamine N-acetyltransferase and uses thereof
WO2019175332A1 (en) 2018-03-14 2019-09-19 Imba - Institut Für Molekulare Biotechnologie Gmbh Bh4 pathway inhibition and use thereof for treating t-cell mediated autoimmune diseases or hypersensitivity
WO2019175328A1 (en) 2018-03-14 2019-09-19 Imba - Institut Für Molekulare Biotechnologie Gmbh Bh4pathwayactivationandusethereoffortreatingcancer
JP7553906B2 (ja) * 2018-11-01 2024-09-19 宏 一瀬 Ｓｐｒをコードするポリヌクレオチドを含む組換えベクター、及びそれを含む組成物
EP3938385A1 (en) 2019-03-15 2022-01-19 Danmarks Tekniske Universitet Engineered cells for production of indole-derivatives
CN111073884A (zh) * 2020-02-14 2020-04-28 昆明理工大学 提高非编码区域距离＜50bp的SNP中具有功能效应的SNP位点检测准确率的方法
CN111505179B (zh) * 2020-04-07 2021-07-13 厦门大学 海洋水体中生物蝶呤的检测方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60178887A (ja) * 1984-02-23 1985-09-12 Kanegafuchi Chem Ind Co Ltd ５，６，７，８−テトラヒドロ−ｌ−ビオプテリンの製造法
JPS619296A (ja) * 1984-06-22 1986-01-16 Kanegafuchi Chem Ind Co Ltd 微生物によるｌ−エリスロ−ビオプテリンの製造法
JPS6152296A (ja) * 1984-08-21 1986-03-14 Kanegafuchi Chem Ind Co Ltd 微生物によるｌ−エリスロ−ビオプテリンの製造法
DE3853711T2 (de) * 1987-11-30 1996-01-11 Vitamin Kenkyusho Kk Zwischenverbindungen für die Synthese von 5,6,7,8-Tetrahydro-L-erythro-biopterin und seiner Derivate.
JP2674707B2 (ja) * 1988-06-22 1997-11-12 株式会社ビタミン研究所 Ｌ‐ビオプテリンの製法
JP2575781B2 (ja) * 1988-02-29 1997-01-29 日清製粉株式会社 ２，３−ジアシルオキシ−４−ヒドロキシ−トペンタナールおよびその製造方法
JP3137333B2 (ja) * 1990-07-21 2001-02-19 サントリー株式会社 テトラヒドロビオプテリンの製法およびそれに用いる酵素
JP2754959B2 (ja) 1991-07-24 1998-05-20 三菱電機株式会社 空気調和機のセンサ識別装置
KR100456062B1 (ko) * 2001-06-18 2004-11-08 박영식 재조합 대장균에 의한 테리딘 화합물의 제조방법

Also Published As

Publication number Publication date
WO2002018587A1 (fr) 2002-03-07
EP1314782A1 (en) 2003-05-28
US20060008869A1 (en) 2006-01-12
JP4817590B2 (ja) 2011-11-16
KR20030033042A (ko) 2003-04-26
DE60138029D1 (de) 2009-04-30
CN1247778C (zh) 2006-03-29
ATE426021T1 (de) 2009-04-15
AU8021501A (en) 2002-03-13
EP1314782B1 (en) 2009-03-18
US20040014167A1 (en) 2004-01-22
JPWO2002018587A1 (ja) 2004-01-15
US7807421B2 (en) 2010-10-05
CA2420374A1 (en) 2003-02-24
AU2001280215B2 (en) 2006-08-03
ES2320531T3 (es) 2009-05-25
IL154530A (en) 2011-02-28
CN1449442A (zh) 2003-10-15
EP1314782A4 (en) 2005-01-12
IL154530A0 (en) 2003-09-17
AU2001280215B9 (en) 2007-03-22
KR100916163B1 (ko) 2009-09-08

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Legal Events

Date Code Title Description
B15G Petition not considered as such [chapter 15.7 patent gazette]
B25D Requested change of name of applicant approved

Owner name: DAIICHI ASUBIO PHARMA CO., LTD. (JP)

Free format text: ALTERADO DE: DAIICHI SUNTORY PHARMA CO., LTD.

B25I Requirement for requested change of headquarter

Owner name: DAIICHI ASUBIO PHARMA CO., LTD. (JP)

Free format text: A FIM DE ATENDER A PETICAO NO 020050140129/RJ DE 02/12/2005, REFERENTE A MUDANCA DE ENDERECO, APRESENTE A GUIA DE RECOLHIMENTO PARA TAL ATO.

B25G Requested change of headquarter approved

Owner name: DAIICHI ASUBIO PHARMA CO., LTD. (JP)

Free format text: SEDE ALTERADA CONFORME SOLICITADO NA PETICAO NO 020050140129/RJ DE 02/12/2005.

B25D Requested change of name of applicant approved

Owner name: ASUBIO PHARMA CO., LTD. (JP)

Free format text: ALTERADO DE: DAIICHI ASUBIO PHARMA CO., LTD.

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06G Technical and formal requirements: other requirements [chapter 6.7 patent gazette]

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B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

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B15K Others concerning applications: alteration of classification

Free format text: AS CLASSIFICACOES ANTERIORES ERAM: C12N 15/09 , C12N 1/15 , C12N 1/19 , C12N 1/21 , C12P 17/18

Ipc: C12P 17/18 (2006.01), C12N 15/52 (2006.01), C12N 1

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

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