ATE545705T1 - Neues induzierbares genexpressionssystem auf ecdysonrezeptor/invertebraten-retinoid-x-rezept r-basis - Google Patents

Neues induzierbares genexpressionssystem auf ecdysonrezeptor/invertebraten-retinoid-x-rezept r-basis

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Publication number
ATE545705T1
ATE545705T1 AT02714955T AT02714955T ATE545705T1 AT E545705 T1 ATE545705 T1 AT E545705T1 AT 02714955 T AT02714955 T AT 02714955T AT 02714955 T AT02714955 T AT 02714955T AT E545705 T1 ATE545705 T1 AT E545705T1
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AT
Austria
Prior art keywords
gene expression
expression system
recipe
system based
inducible gene
Prior art date
Application number
AT02714955T
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English (en)
Inventor
Subba Palli
Marianna Zinovjevna Kapitskaya
Original Assignee
Intrexon Corp
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Application filed by Intrexon Corp filed Critical Intrexon Corp
Application granted granted Critical
Publication of ATE545705T1 publication Critical patent/ATE545705T1/de

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/721Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70567Nuclear receptors, e.g. retinoic acid receptor [RAR], RXR, nuclear orphan receptors

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Wood Science & Technology (AREA)
  • High Energy & Nuclear Physics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT02714955T 2001-02-20 2002-02-20 Neues induzierbares genexpressionssystem auf ecdysonrezeptor/invertebraten-retinoid-x-rezept r-basis ATE545705T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26979901P 2001-02-20 2001-02-20
US29481401P 2001-05-31 2001-05-31
PCT/US2002/005235 WO2002066613A2 (en) 2001-02-20 2002-02-20 Novel ecdysone receptor/invertebrate retinoid x receptor-based inducible gene expression system

Publications (1)

Publication Number Publication Date
ATE545705T1 true ATE545705T1 (de) 2012-03-15

Family

ID=26953897

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02714955T ATE545705T1 (de) 2001-02-20 2002-02-20 Neues induzierbares genexpressionssystem auf ecdysonrezeptor/invertebraten-retinoid-x-rezept r-basis

Country Status (11)

Country Link
US (2) US9493540B2 (de)
EP (1) EP1456346B1 (de)
JP (3) JP4955904B2 (de)
AT (1) ATE545705T1 (de)
AU (2) AU2002247184B2 (de)
CA (1) CA2441444C (de)
DK (1) DK1456346T3 (de)
ES (1) ES2385598T3 (de)
MX (1) MXPA03007493A (de)
PT (1) PT1456346E (de)
WO (1) WO2002066613A2 (de)

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JP2004533214A (ja) 2004-11-04
CA2441444A1 (en) 2002-08-29
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JP5887301B2 (ja) 2016-03-16
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JP2009131259A (ja) 2009-06-18
JP4955904B2 (ja) 2012-06-20
WO2002066613A2 (en) 2002-08-29
US9493540B2 (en) 2016-11-15
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US20170096672A1 (en) 2017-04-06
CA2441444C (en) 2013-09-03
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