ATE540944T1 - Pyridylpiperidinorexin-rezeptorantagonisten - Google Patents

Pyridylpiperidinorexin-rezeptorantagonisten

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Publication number
ATE540944T1
ATE540944T1 AT08754659T AT08754659T ATE540944T1 AT E540944 T1 ATE540944 T1 AT E540944T1 AT 08754659 T AT08754659 T AT 08754659T AT 08754659 T AT08754659 T AT 08754659T AT E540944 T1 ATE540944 T1 AT E540944T1
Authority
AT
Austria
Prior art keywords
pyridylpiperidinorexine
receptor antagonists
compounds
orexin receptors
diseases
Prior art date
Application number
AT08754659T
Other languages
German (de)
English (en)
Inventor
Michael Breslin
Paul Coleman
Christopher Cox
John Schreier
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Application granted granted Critical
Publication of ATE540944T1 publication Critical patent/ATE540944T1/de

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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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AT08754659T 2007-05-23 2008-05-22 Pyridylpiperidinorexin-rezeptorantagonisten ATE540944T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93145807P 2007-05-23 2007-05-23
PCT/US2008/006563 WO2008147518A1 (en) 2007-05-23 2008-05-22 Pyridyl piperidine orexin receptor antagonists

Publications (1)

Publication Number Publication Date
ATE540944T1 true ATE540944T1 (de) 2012-01-15

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