ATE537828T1 - Psychotropes mittel und nahrungsmittel zur förderung der gesundheit enthaltend neferin - Google Patents
Psychotropes mittel und nahrungsmittel zur förderung der gesundheit enthaltend neferinInfo
- Publication number
- ATE537828T1 ATE537828T1 AT05767135T AT05767135T ATE537828T1 AT E537828 T1 ATE537828 T1 AT E537828T1 AT 05767135 T AT05767135 T AT 05767135T AT 05767135 T AT05767135 T AT 05767135T AT E537828 T1 ATE537828 T1 AT E537828T1
- Authority
- AT
- Austria
- Prior art keywords
- neferine
- foods
- promoting health
- psychotropic agents
- health containing
- Prior art date
Links
- 239000004089 psychotropic agent Substances 0.000 title abstract 2
- MIBATSHDJRIUJK-ROJLCIKYSA-N Neferine Chemical compound C1=CC(OC)=CC=C1C[C@@H]1C2=CC(OC=3C(=CC=C(C[C@@H]4C5=CC(OC)=C(OC)C=C5CCN4C)C=3)O)=C(OC)C=C2CCN1C MIBATSHDJRIUJK-ROJLCIKYSA-N 0.000 title 1
- MIBATSHDJRIUJK-UHFFFAOYSA-N Neferine Natural products C1=CC(OC)=CC=C1CC1C2=CC(OC=3C(=CC=C(CC4C5=CC(OC)=C(OC)C=C5CCN4C)C=3)O)=C(OC)C=C2CCN1C MIBATSHDJRIUJK-UHFFFAOYSA-N 0.000 title 1
- 235000013305 food Nutrition 0.000 title 1
- 230000001737 promoting effect Effects 0.000 title 1
- LZJWNVLTWYMMDJ-GOSISDBHSA-N O-Methylarmepavine Chemical compound C1=CC(OC)=CC=C1C[C@@H]1C2=CC(OC)=C(OC)C=C2CCN1C LZJWNVLTWYMMDJ-GOSISDBHSA-N 0.000 abstract 1
- LZJWNVLTWYMMDJ-UHFFFAOYSA-N O-Methylarmepavine Natural products C1=CC(OC)=CC=C1CC1C2=CC(OC)=C(OC)C=C2CCN1C LZJWNVLTWYMMDJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/18—Aralkyl radicals
- C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004227227 | 2004-08-03 | ||
| PCT/JP2005/013950 WO2006013792A1 (ja) | 2004-08-03 | 2005-07-29 | ベンジルイソキノリン誘導体またはビスベンジルイソキノリン誘導体を含有する向精神薬、鎮痛薬および／または抗炎症薬、ならびに健康食品 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE537828T1 true ATE537828T1 (de) | 2012-01-15 |
Family
ID=35758225
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05767135T ATE537828T1 (de) | 2004-08-03 | 2005-07-29 | Psychotropes mittel und nahrungsmittel zur förderung der gesundheit enthaltend neferin |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US7799802B2 (de) |
| EP (2) | EP2305260B1 (de) |
| JP (2) | JP4698595B2 (de) |
| AT (1) | ATE537828T1 (de) |
| WO (1) | WO2006013792A1 (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4799434B2 (ja) * | 2007-01-31 | 2011-10-26 | イスクラ産業株式会社 | 向精神剤 |
| CN101862331B (zh) * | 2009-04-14 | 2013-05-22 | 中国中医科学院中药研究所 | 甲基莲心碱的新用途 |
| CN101862374B (zh) * | 2010-06-12 | 2014-12-31 | 李宏 | 莲子心及其提取物的新用途 |
| JP5992691B2 (ja) * | 2011-02-02 | 2016-09-14 | 丸善製薬株式会社 | ヒアルロン酸産生促進剤、及び、ｉｉ型コラーゲン産生促進剤 |
| US9745269B2 (en) | 2013-03-15 | 2017-08-29 | Cba Pharma, Inc. | Supercritical fluid extraction of bis-benzyl isoquinolines |
| JP2016514142A (ja) * | 2013-03-15 | 2016-05-19 | シービーエー・ファーマ・インコーポレイテッドCba Pharma, Inc. | 薬物及び栄養補助剤のバイオアベイラビリティを高める方法及び生成物 |
| CN103554022B (zh) * | 2013-10-31 | 2015-12-30 | 苏州永健生物医药有限公司 | 一种盐酸去甲乌药碱的合成方法 |
| KR101606494B1 (ko) * | 2014-04-02 | 2016-03-28 | 연세대학교 산학협력단 | 비스벤질이소퀴놀린계 알칼로이드를 유효성분으로 함유하는 골 질환 예방 및 치료용 조성물 |
| CN104744367B (zh) * | 2015-04-03 | 2017-10-13 | 辽宁大学 | 莲子心生物碱的闪式提取方法 |
| KR101655274B1 (ko) * | 2015-11-10 | 2016-09-07 | 연세대학교 산학협력단 | 아포핀계 알칼로이드를 유효성분으로 함유하는 골 질환 예방 및 치료용 조성물 |
| CN105434335B (zh) * | 2016-01-15 | 2018-05-11 | 武汉大学 | 一种莲心碱栓剂及其制备方法和用途 |
| CN106031725B (zh) * | 2016-05-18 | 2017-03-08 | 广东奇方药业有限公司 | 荷叶碱和其类似物的药物应用 |
| US12459965B2 (en) | 2017-10-09 | 2025-11-04 | Compass Pathfinder Limited | Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use |
| GB2571696B (en) | 2017-10-09 | 2020-05-27 | Compass Pathways Ltd | Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced |
| CN109718238A (zh) * | 2017-10-31 | 2019-05-07 | 中国中医科学院中药研究所 | 一种化合物治疗缺血性脑病的新用途 |
| CN111135172A (zh) * | 2018-11-05 | 2020-05-12 | 中国中医科学院中药研究所 | 一种化合物治疗咽炎的新用途 |
| AU2020258086A1 (en) | 2019-04-17 | 2021-11-11 | Compass Pathfinder Limited | Methods of treating neurocognitive disorders, chronic pain and reducing inflammation |
| CN110585208A (zh) * | 2019-09-25 | 2019-12-20 | 山东中医药大学 | 莲心碱作为5-脂氧合酶抑制剂的应用 |
| CN112546060B (zh) * | 2020-12-15 | 2021-08-31 | 北京中医药大学 | 降脂的中药单体组合物、制剂及用途 |
| CN112546052A (zh) * | 2020-12-28 | 2021-03-26 | 青岛博智汇力生物科技有限公司 | 一种含有海洋寡糖防治痛风的组合物 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4719234A (en) * | 1985-12-20 | 1988-01-12 | Warner-Lambert Company | Benzoic acid and benzoic acid ester derivatives to treat inflammation |
| JPS63208519A (ja) * | 1987-02-23 | 1988-08-30 | Kaken Shiyouyaku Kk | 発癌促進物質抑制剤 |
| JPS6490129A (en) | 1987-09-30 | 1989-04-06 | Kodama Kk | Pharmaceutical composition containing extract of lotus embryo |
| US5627195A (en) * | 1995-04-11 | 1997-05-06 | Massachusetts Eye And Ear Infirmary | Treatment for ocular inflammation |
| JPH11158077A (ja) | 1997-12-02 | 1999-06-15 | Nissei Marine Kogyo Kk | ストレス軽減効果のある組成物 |
| JPH11180873A (ja) * | 1997-12-22 | 1999-07-06 | Kaken Shoyaku Kk | ＮＦ−κＢ活性阻害剤 |
| US6476208B1 (en) * | 1998-10-13 | 2002-11-05 | Genset | Schizophrenia associated genes, proteins and biallelic markers |
| JP4693963B2 (ja) | 2000-07-12 | 2011-06-01 | 丸善製薬株式会社 | エストロゲン様作用剤、コラーゲン産生促進剤、及び線維芽細胞増殖剤 |
| JP2003113100A (ja) | 2001-10-01 | 2003-04-18 | Pola Chem Ind Inc | 熱産生タンパク質発現促進剤及びそれを含有する組成物 |
| WO2005021021A1 (en) | 2002-04-01 | 2005-03-10 | Purimed Co., Ltd. | Extract of nelumbinis semen for the treatment of depression |
| KR100513489B1 (ko) | 2002-04-01 | 2005-09-09 | 퓨리메드 주식회사 | 우울증 치료용 연자육 추출물 |
| KR100554082B1 (ko) | 2002-09-23 | 2006-02-22 | 학교법인 경희대학교 | 연자육의 진통효과 검증방법 및 연자육 진통 제제 |
| KR100572621B1 (ko) | 2003-03-19 | 2006-04-24 | 한국 한의학 연구원 | 비만 및 성인병 치료용 조성물 |
-
2004
- 2004-09-27 US US10/949,247 patent/US7799802B2/en active Active
-
2005
- 2005-07-29 EP EP10181082A patent/EP2305260B1/de not_active Expired - Lifetime
- 2005-07-29 WO PCT/JP2005/013950 patent/WO2006013792A1/ja not_active Ceased
- 2005-07-29 AT AT05767135T patent/ATE537828T1/de active
- 2005-07-29 US US10/571,199 patent/US20070027181A1/en not_active Abandoned
- 2005-07-29 JP JP2006531440A patent/JP4698595B2/ja not_active Expired - Lifetime
- 2005-07-29 EP EP05767135A patent/EP1774968B1/de not_active Expired - Lifetime
-
2010
- 2010-10-19 JP JP2010234965A patent/JP5226053B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20070027181A1 (en) | 2007-02-01 |
| US20060030586A1 (en) | 2006-02-09 |
| EP1774968A1 (de) | 2007-04-18 |
| EP1774968B1 (de) | 2011-12-21 |
| EP1774968A4 (de) | 2007-11-07 |
| US7799802B2 (en) | 2010-09-21 |
| WO2006013792A1 (ja) | 2006-02-09 |
| JPWO2006013792A1 (ja) | 2008-05-01 |
| JP5226053B2 (ja) | 2013-07-03 |
| EP2305260B1 (de) | 2012-12-05 |
| JP2011012086A (ja) | 2011-01-20 |
| JP4698595B2 (ja) | 2011-06-08 |
| EP2305260A1 (de) | 2011-04-06 |
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