ATE537814T1 - Nanoliposom mit verestertem lecithin und herstellungsverfahren dafür und dieses enthaltende zusammensetzung zur prävention oder behandlung von hauterkrankungen - Google Patents
Nanoliposom mit verestertem lecithin und herstellungsverfahren dafür und dieses enthaltende zusammensetzung zur prävention oder behandlung von hauterkrankungenInfo
- Publication number
- ATE537814T1 ATE537814T1 AT07793354T AT07793354T ATE537814T1 AT E537814 T1 ATE537814 T1 AT E537814T1 AT 07793354 T AT07793354 T AT 07793354T AT 07793354 T AT07793354 T AT 07793354T AT E537814 T1 ATE537814 T1 AT E537814T1
- Authority
- AT
- Austria
- Prior art keywords
- nanoliposome
- skin
- skin diseases
- esterified lecithin
- penetration
- Prior art date
Links
- 208000017520 skin disease Diseases 0.000 title abstract 5
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 title abstract 4
- 229940067606 lecithin Drugs 0.000 title abstract 4
- 235000010445 lecithin Nutrition 0.000 title abstract 4
- 239000000787 lecithin Substances 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 239000002502 liposome Substances 0.000 abstract 4
- 239000012528 membrane Substances 0.000 abstract 3
- 102000009024 Epidermal Growth Factor Human genes 0.000 abstract 2
- 101800003838 Epidermal growth factor Proteins 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 229940116977 epidermal growth factor Drugs 0.000 abstract 2
- 230000003020 moisturizing effect Effects 0.000 abstract 2
- 230000004936 stimulating effect Effects 0.000 abstract 2
- VBEQCZHXXJYVRD-GACYYNSASA-N uroanthelone Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CS)C(=O)N[C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(C)C)[C@@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CCSC)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)CNC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CS)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CS)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(N)=O)C(C)C)[C@@H](C)CC)C1=CC=C(O)C=C1 VBEQCZHXXJYVRD-GACYYNSASA-N 0.000 abstract 2
- 239000002537 cosmetic Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 230000007774 longterm Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000000149 penetrating effect Effects 0.000 abstract 1
- 230000035515 penetration Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/14—Liposomes; Vesicles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
- A61K8/553—Phospholipids, e.g. lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
- A61K2800/413—Nanosized, i.e. having sizes below 100 nm
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Nanotechnology (AREA)
- Medical Informatics (AREA)
- Toxicology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020060072809A KR100752990B1 (ko) | 2006-08-02 | 2006-08-02 | 나노리포좀 및 천연 추출물을 포함하는 피부 질환의 예방또는 치료용 조성물 |
| PCT/KR2007/003699 WO2008016258A1 (en) | 2006-08-02 | 2007-08-01 | Nanoliposome using esterified lecithin and method for preparing the same, and composition for preventing or treating skin diseases comprising the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE537814T1 true ATE537814T1 (de) | 2012-01-15 |
Family
ID=38615652
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07793354T ATE537814T1 (de) | 2006-08-02 | 2007-08-01 | Nanoliposom mit verestertem lecithin und herstellungsverfahren dafür und dieses enthaltende zusammensetzung zur prävention oder behandlung von hauterkrankungen |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8685440B2 (de) |
| EP (1) | EP2054035B1 (de) |
| JP (1) | JP5191988B2 (de) |
| KR (1) | KR100752990B1 (de) |
| CN (1) | CN101511340B (de) |
| AT (1) | ATE537814T1 (de) |
| RU (1) | RU2418575C2 (de) |
| TW (1) | TWI325325B (de) |
| WO (1) | WO2008016258A1 (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100824958B1 (ko) | 2006-12-05 | 2008-04-28 | 주식회사 피코스텍 | 한방 추출물과 나노 세라마이드를 함유하는 화장품 조성물 |
| ES2325901B1 (es) * | 2008-02-20 | 2010-07-06 | Heber Farma Sl | Vehiculizacion del factor de crecimiento epidermico a traves de biomembranas. |
| WO2012094033A1 (en) * | 2011-01-05 | 2012-07-12 | Livon Laboratories | Methods of making liposomes, liposome compositions made by the methods, and methods of using the same |
| KR101290790B1 (ko) | 2011-06-22 | 2013-07-30 | 제이앤씨화장품 주식회사 | 한방 나노좀을 함유하는 피부트러블 개선 및 진정효과를 갖는 화장료 조성물 |
| KR101421171B1 (ko) * | 2011-08-31 | 2014-07-22 | 재단법인 제이씨비 공동생물과학연구소 | 인간 골형성 단백질 수용체 1ａ의 세포외 도메인을 유효성분으로 포함하는 피부 상태 개선용 조성물 |
| WO2014079020A1 (en) * | 2012-11-22 | 2014-05-30 | Original Biomedicals Co., Ltd. | Pharmaceutical composition used for reducing damage caused by free radicals |
| RU2482867C1 (ru) * | 2012-03-20 | 2013-05-27 | Федеральное государственное бюджетное учреждение "Научный центр неврологии" Российской академии медицинских наук (ФГБУ "НЦН" РАМН) | Применение l-карнозина для приготовления нанопрепарата, обладающего антигипоксической и антиоксидантной активностью |
| JP6000033B2 (ja) * | 2012-09-18 | 2016-09-28 | 株式会社ピカソ美化学研究所 | 内包物質に耐熱性を与えたリポソーム及びその製造方法 |
| CN104127326B (zh) * | 2014-07-10 | 2017-01-11 | 上海应用技术学院 | 一种包覆Vc棕榈酸酯的纳米固体脂质载体及其制备方法 |
| EP3241565A4 (de) | 2014-12-30 | 2018-07-18 | Celltrion, Inc. | Hybride multilamellare nanostruktur des epidermalen wachstumsfaktors und liposom und verfahren zur herstellung davon |
| US11419820B2 (en) * | 2016-03-30 | 2022-08-23 | Riken Vitamin Co., Ltd. | Carotenoid-containing particles |
| CN106963975B (zh) * | 2017-03-08 | 2019-12-27 | 广州欧化药业有限公司 | 白芨胶自组装纳米微粒及其制备方法和应用 |
| CN110536674A (zh) * | 2017-05-23 | 2019-12-03 | 大江生医股份有限公司 | 乳化脂质体组合物及其制备方法 |
| CN107519114A (zh) * | 2017-10-19 | 2017-12-29 | 广州无添加主义化妆品有限公司 | 一种护肤面膜及其制备方法 |
| CN108309939B (zh) * | 2018-03-23 | 2020-06-05 | 中国中医科学院中药研究所 | 一种含有五味子木脂素类化合物的纳米结构脂质载体及其制备方法和测定方法 |
| CN108283603A (zh) * | 2018-04-02 | 2018-07-17 | 吴伟华 | 一种劳保护肤膏的制备方法 |
| RU2740553C2 (ru) * | 2019-01-30 | 2021-01-15 | Анастасия Андреевна Карбаинова | Способ получения липосомальной формы бетулина, обладающей гепатопротекторной активностью |
| CN111803396A (zh) * | 2020-06-30 | 2020-10-23 | 黑龙江省医院 | 一种基于视黄醛和双甘氨肽油酰胺的化妆品组合物及其制备方法 |
| CN113143811B (zh) * | 2020-12-14 | 2023-01-24 | 洛阳师范学院 | 一种牡丹花提取物复合脂质体的制备方法 |
| CN112494351A (zh) * | 2020-12-21 | 2021-03-16 | 上海毕图生物科技有限公司 | 一种作用于皮肤细胞抗氧化精华液的制备方法 |
| CN113876713B (zh) * | 2021-11-23 | 2023-02-03 | 河南省儿童医院郑州儿童医院 | 一种阿莫西林钠克拉维酸钾脂质体及其制备方法 |
| CN118286155B (zh) * | 2024-04-08 | 2025-01-28 | 江门职业技术学院 | 一种超纳米包裹体系及其制备方法 |
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| US4944948A (en) * | 1989-02-24 | 1990-07-31 | Liposome Technology, Inc. | EGF/Liposome gel composition and method |
| WO1990011781A1 (en) | 1989-04-04 | 1990-10-18 | Alcon Laboratories, Inc. | The use of liposomes for the delivery of therapeutic agents to wounds, cuts and abrasions |
| US5109118A (en) * | 1989-07-06 | 1992-04-28 | Yutaka Mizushima | Modified biologically active proteins |
| JPH0348614A (ja) * | 1989-07-17 | 1991-03-01 | Wakunaga Pharmaceut Co Ltd | 上皮細胞成長因子結合リポソーム |
| US6165500A (en) * | 1990-08-24 | 2000-12-26 | Idea Ag | Preparation for the application of agents in mini-droplets |
| US5498420A (en) * | 1991-04-12 | 1996-03-12 | Merz & Co. Gmbh & Co. | Stable small particle liposome preparations, their production and use in topical cosmetic, and pharmaceutical compositions |
| FR2714602B1 (fr) * | 1993-12-30 | 1996-02-09 | Oreal | Composition antiacnéique pour le traitement simultané des couches superficielles et profondes de la peau, son utilisation. |
| US5834016A (en) | 1996-04-04 | 1998-11-10 | Cilag Ag | Liposome-based topical vitamin D formulation |
| IT1291278B1 (it) * | 1996-07-05 | 1999-01-07 | Errekappa Euroterapici S P A | Preparazione farmaceutica a base di nimesulide per uso topico |
| KR100366439B1 (ko) | 2000-02-21 | 2003-01-09 | 주식회사 대웅 | 상피세포 성장인자를 유효성분으로 하는 안정한 약제학적조성물 |
| JP2003002824A (ja) * | 2001-06-21 | 2003-01-08 | Biibanjiyoa Kk | アスコルビン酸を内部に含むリポソーム |
| EP1631561B1 (de) | 2003-05-07 | 2010-08-18 | General Electric Company | Zusammensetzungen und verfahren zur in vivo abbildung von loeslichen beta-amyloid |
| KR20040101709A (ko) * | 2003-05-26 | 2004-12-03 | 나드리화장품주식회사 | 동백나무 추출물을 안정화시킨 나노리포좀을 함유하는화장료 조성물 |
| KR20050040595A (ko) * | 2003-10-29 | 2005-05-03 | 주식회사 엘지생활건강 | 피부주름개선 화장료 조성물 |
| FR2862306B1 (fr) * | 2003-11-17 | 2008-05-30 | Aventis Pasteur | Composition vaccinale |
| KR100530880B1 (ko) * | 2003-12-05 | 2005-11-23 | 한국콜마 주식회사 | 나노사이즈의 인지질 리포좀 화장료 및 그 제조방법 |
| KR100556524B1 (ko) | 2003-12-12 | 2006-03-06 | 코스맥스 주식회사 | 항염증 및 항산화 활성을 갖는 동백 추출물 및 이를함유한 화장료 조성물 |
| KR100603814B1 (ko) * | 2004-03-11 | 2006-07-25 | 바이오스펙트럼 주식회사 | 나노리포좀 조성물 |
| KR100553160B1 (ko) * | 2004-07-09 | 2006-02-22 | 한국콜마 주식회사 | 코엔자임 큐10을 포함하는 나노크기의 인지질 리포좀조성물 및 그 제조방법 |
| KR100642526B1 (ko) | 2004-09-16 | 2006-11-03 | 코스맥스 주식회사 | 항염증 및 항산화 활성을 갖는 겨우살이 추출물 및 이를함유한 화장료 조성물 |
| KR100768151B1 (ko) * | 2006-04-10 | 2007-10-17 | 주식회사 대웅 | 에스터화 레시딘을 이용한 나노리포좀 |
-
2006
- 2006-08-02 KR KR1020060072809A patent/KR100752990B1/ko active Active
-
2007
- 2007-08-01 WO PCT/KR2007/003699 patent/WO2008016258A1/en not_active Ceased
- 2007-08-01 EP EP07793354A patent/EP2054035B1/de active Active
- 2007-08-01 AT AT07793354T patent/ATE537814T1/de active
- 2007-08-01 TW TW096128163A patent/TWI325325B/zh active
- 2007-08-01 RU RU2009107154/15A patent/RU2418575C2/ru active
- 2007-08-01 JP JP2009522716A patent/JP5191988B2/ja active Active
- 2007-08-01 CN CN2007800327079A patent/CN101511340B/zh active Active
- 2007-08-01 US US12/375,739 patent/US8685440B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| RU2418575C2 (ru) | 2011-05-20 |
| KR100752990B1 (ko) | 2007-08-30 |
| JP5191988B2 (ja) | 2013-05-08 |
| EP2054035B1 (de) | 2011-12-21 |
| EP2054035A4 (de) | 2011-03-23 |
| WO2008016258A1 (en) | 2008-02-07 |
| CN101511340B (zh) | 2011-11-16 |
| CN101511340A (zh) | 2009-08-19 |
| TW200815021A (en) | 2008-04-01 |
| US20090263473A1 (en) | 2009-10-22 |
| JP2009545587A (ja) | 2009-12-24 |
| RU2009107154A (ru) | 2010-09-10 |
| TWI325325B (en) | 2010-06-01 |
| EP2054035A1 (de) | 2009-05-06 |
| US8685440B2 (en) | 2014-04-01 |
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