ATE529188T1 - Extraktionskolonnenvorrichtung - Google Patents

Extraktionskolonnenvorrichtung

Info

Publication number
ATE529188T1
ATE529188T1 AT03764635T AT03764635T ATE529188T1 AT E529188 T1 ATE529188 T1 AT E529188T1 AT 03764635 T AT03764635 T AT 03764635T AT 03764635 T AT03764635 T AT 03764635T AT E529188 T1 ATE529188 T1 AT E529188T1
Authority
AT
Austria
Prior art keywords
volume
columns
analyte
low
extraction column
Prior art date
Application number
AT03764635T
Other languages
English (en)
Inventor
Douglas Gjerde
Christopher Hanna
Original Assignee
Phynexus Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phynexus Inc filed Critical Phynexus Inc
Application granted granted Critical
Publication of ATE529188T1 publication Critical patent/ATE529188T1/de

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00Nanotechnology for materials or surface science, e.g. nanocomposites
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282Porous sorbents
    • B01J20/285Porous sorbents based on polymers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/291Gel sorbents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/0275Interchangeable or disposable dispensing tips
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/32Bonded phase chromatography
    • B01D15/325Reversed phase
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/32Bonded phase chromatography
    • B01D15/325Reversed phase
    • B01D15/327Reversed phase with hydrophobic interaction
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804Affinity chromatography
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00Aspects relating to sorbent materials
    • B01J2220/50Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/64In a syringe, pipette, e.g. tip or in a tube, e.g. test-tube or u-shape tube
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0631Purification arrangements, e.g. solid phase extraction [SPE]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N2030/009Extraction
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027General features of the devices
    • G01N2035/1034Transferring microquantities of liquid
    • G01N2035/1039Micropipettes, e.g. microcapillary tubes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/60Construction of the column
    • G01N30/6004Construction of the column end pieces
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y10T436/255Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nanotechnology (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Composite Materials (AREA)
  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Materials Engineering (AREA)
  • Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
AT03764635T 2002-07-15 2003-07-14 Extraktionskolonnenvorrichtung ATE529188T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39659502P 2002-07-15 2002-07-15
US46560603P 2003-04-25 2003-04-25
PCT/US2003/021998 WO2004007081A1 (en) 2002-07-15 2003-07-14 Low dead volume extraction column devices

Publications (1)

Publication Number Publication Date
ATE529188T1 true ATE529188T1 (de) 2011-11-15

Family

ID=30118592

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03764635T ATE529188T1 (de) 2002-07-15 2003-07-14 Extraktionskolonnenvorrichtung

Country Status (6)

Country Link
US (1) US7482169B2 (de)
EP (1) EP1521637B1 (de)
JP (1) JP2006515562A (de)
AT (1) ATE529188T1 (de)
AU (1) AU2003249231A1 (de)
WO (1) WO2004007081A1 (de)

Families Citing this family (108)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6048734A (en) 1995-09-15 2000-04-11 The Regents Of The University Of Michigan Thermal microvalves in a fluid flow method
US6692700B2 (en) 2001-02-14 2004-02-17 Handylab, Inc. Heat-reduction methods and systems related to microfluidic devices
US7010391B2 (en) 2001-03-28 2006-03-07 Handylab, Inc. Methods and systems for control of microfluidic devices
US8895311B1 (en) 2001-03-28 2014-11-25 Handylab, Inc. Methods and systems for control of general purpose microfluidic devices
US7829025B2 (en) 2001-03-28 2010-11-09 Venture Lending & Leasing Iv, Inc. Systems and methods for thermal actuation of microfluidic devices
US7323140B2 (en) 2001-03-28 2008-01-29 Handylab, Inc. Moving microdroplets in a microfluidic device
US6852287B2 (en) 2001-09-12 2005-02-08 Handylab, Inc. Microfluidic devices having a reduced number of input and output connections
US7335337B1 (en) * 2001-09-11 2008-02-26 Smith James C Ergonomic pipette tip and adapters
US7151167B2 (en) 2002-06-10 2006-12-19 Phynexus, Inc. Open channel solid phase extraction systems and methods
US7122640B2 (en) 2002-06-10 2006-10-17 Phynexus, Inc. Open channel solid phase extraction systems and methods
US7879621B2 (en) 2003-05-08 2011-02-01 Phynexus, Inc. Open channel solid phase extraction systems and methods
US7601545B2 (en) * 2003-06-20 2009-10-13 Groton Biosystems, Llc Automated macromolecule sample preparation system
US7722820B2 (en) * 2004-11-19 2010-05-25 Phynexus, Inc. Method and device for sample preparation
US20090081084A1 (en) * 2003-07-14 2009-03-26 Gjerde Douglas T Low Dead Volume Extraction Column Device
JP4996248B2 (ja) 2003-07-31 2012-08-08 ハンディーラブ インコーポレイテッド 粒子含有サンプルの処理
TWI253352B (en) * 2003-12-26 2006-04-21 Ind Tech Res Inst Solid-phase micro extraction device
EP1702210B1 (de) * 2004-01-08 2022-08-24 Phynexus, Inc. Verfahren und vorrichtung zur probenpräparation
US20050258097A1 (en) * 2004-01-08 2005-11-24 Gjerde Douglas T Method and device for extracting an analyte
JP4090443B2 (ja) * 2004-02-24 2008-05-28 株式会社日立ハイテクノロジーズ 核酸回収器具、その部品、及び核酸回収器具の生産方法
US7161145B2 (en) * 2004-04-21 2007-01-09 Sri International Method and apparatus for the detection and identification of trace organic substances from a continuous flow sample system using laser photoionization-mass spectrometry
EP2345739B8 (de) 2004-05-03 2016-12-07 Handylab, Inc. Mikrofluidische Vorrichtung zur Verarbeitung polynukleotidhaltiger Proben
US8852862B2 (en) 2004-05-03 2014-10-07 Handylab, Inc. Method for processing polynucleotide-containing samples
JP4558382B2 (ja) * 2004-06-04 2010-10-06 ジーエルサイエンス株式会社 アフィニティクロマトグラフィ用デバイス及びその製法
CA2575077A1 (en) * 2004-07-23 2006-02-02 Biosystem Development, Llc Immunoassay assembly and methods of use
US7602495B2 (en) * 2004-08-24 2009-10-13 Fujifilm Corporation Method for measuring dissociation constant by surface plasmon resonance analysis
US8187441B2 (en) * 2004-10-19 2012-05-29 Evans Christine E Electrochemical pump
WO2006073170A1 (ja) * 2005-01-07 2006-07-13 Universal Bio Research Co., Ltd. 担体封入チップ、担体処理装置、および担体処理方法
DE102005005437A1 (de) * 2005-02-05 2006-08-10 Eppendorf Ag Filterpipettenspitze
US8124028B2 (en) 2005-07-25 2012-02-28 Agilent Technologies, Inc. Automated liquid handling device and associated assay unit
DE102005053463A1 (de) * 2005-11-06 2007-05-10 Aj Innuscreen Gmbh Vorrichtung und Verfahren zur automatisierten Isolierung und Aufreinigung von Nukleinsäuren aus beliebigen komplexen Ausgangsmaterialien
US10900066B2 (en) 2006-03-24 2021-01-26 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US7998708B2 (en) 2006-03-24 2011-08-16 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US11806718B2 (en) 2006-03-24 2023-11-07 Handylab, Inc. Fluorescence detector for microfluidic diagnostic system
WO2007112114A2 (en) 2006-03-24 2007-10-04 Handylab, Inc. Integrated system for processing microfluidic samples, and method of using same
US8088616B2 (en) 2006-03-24 2012-01-03 Handylab, Inc. Heater unit for microfluidic diagnostic system
US8883490B2 (en) 2006-03-24 2014-11-11 Handylab, Inc. Fluorescence detector for microfluidic diagnostic system
GB2439050A (en) * 2006-06-13 2007-12-19 Zhanren Zhang Disposable chromatography device
US8709787B2 (en) 2006-11-14 2014-04-29 Handylab, Inc. Microfluidic cartridge and method of using same
US8012349B2 (en) 2006-11-20 2011-09-06 Orbital Biosciences, Llc Small volume unitary molded filters and supports for adsorbent beds
US20080145950A1 (en) * 2006-12-14 2008-06-19 Gjerde Douglas T Method for extracting an analyte
JP2010529416A (ja) * 2007-02-21 2010-08-26 ウィリアム ブリューワー 抽出、試料捕集及び試料クリーンアップ用ピペットチップとその使用方法
WO2008150763A1 (en) * 2007-05-29 2008-12-11 Waters Investments Limited Apparatus and methods for multidimensional analysis
US9186677B2 (en) 2007-07-13 2015-11-17 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
WO2009012185A1 (en) 2007-07-13 2009-01-22 Handylab, Inc. Polynucleotide capture materials, and methods of using same
US8287820B2 (en) 2007-07-13 2012-10-16 Handylab, Inc. Automated pipetting apparatus having a combined liquid pump and pipette head system
US9618139B2 (en) 2007-07-13 2017-04-11 Handylab, Inc. Integrated heater and magnetic separator
USD621060S1 (en) 2008-07-14 2010-08-03 Handylab, Inc. Microfluidic cartridge
US8182763B2 (en) 2007-07-13 2012-05-22 Handylab, Inc. Rack for sample tubes and reagent holders
US20090136385A1 (en) 2007-07-13 2009-05-28 Handylab, Inc. Reagent Tube
US8133671B2 (en) 2007-07-13 2012-03-13 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US8105783B2 (en) 2007-07-13 2012-01-31 Handylab, Inc. Microfluidic cartridge
EP2060625A1 (de) * 2007-11-16 2009-05-20 Dentognostics GMBH Vorrichtung zur Elution von zur Analyse vorgesehenen Proben
WO2009121032A2 (en) * 2008-03-28 2009-10-01 Pelican Group Holdings, Inc. Sample preparation devices and methods for processing analytes
US8202495B1 (en) * 2008-06-23 2012-06-19 Smith James C Ergonomic pipette tip
KR101006562B1 (ko) * 2008-06-27 2011-01-07 포항공과대학교 산학협력단 핵산 추출 방법
KR101005924B1 (ko) * 2008-06-27 2011-01-06 포항공과대학교 산학협력단 핵산 추출 장치
USD618820S1 (en) 2008-07-11 2010-06-29 Handylab, Inc. Reagent holder
USD787087S1 (en) 2008-07-14 2017-05-16 Handylab, Inc. Housing
WO2010083282A1 (en) * 2009-01-15 2010-07-22 The Charles Stark Draper Laboratory, Inc. High-throughput biological screening
CH700283A1 (de) * 2009-01-23 2010-07-30 Werner Doebelin Probenhandling- und Injektions-System für die HPLC mit verschliessbaren Pipettenspitzen.
CN102439128A (zh) 2009-02-14 2012-05-02 第菲尼特基因组学公司 用于纯化生物物质的系统和方法
US8776621B2 (en) * 2009-03-06 2014-07-15 Dionex Corporation Fluid sample delivery system and method
US8900453B2 (en) * 2009-10-22 2014-12-02 Samuel S. Miller Plant oil extract device and method for using the same
US9370732B2 (en) * 2013-02-15 2016-06-21 Douglas T. Gjerde Methods for purifying biological cells
US8816064B2 (en) * 2010-09-30 2014-08-26 Phynexus, Inc. Purification of nucleic acids
BR112013015141B1 (pt) * 2010-12-17 2021-06-29 Biomerieux, Inc. Dispositivo de transferência de amostra e filtração integrado, montagem de transferência de amostra e filtração, e método de isolamento e identificação de um microorganismo de uma amostra de teste
US20130337577A1 (en) * 2010-12-29 2013-12-19 Cubrc, Inc. Extraction Pipette
US10866170B2 (en) 2011-01-24 2020-12-15 Roche Molecular Systems, Inc Devices, systems, and methods for extracting a material from a material sample
WO2012103214A2 (en) 2011-01-26 2012-08-02 Molecular Bioproducts, Inc. Magnetic pipette tip
CN102680588B (zh) * 2011-03-09 2015-10-28 常州博闻迪医药科技有限公司 一种柱层析分离检测技术及其用途
US11274292B2 (en) 2011-03-29 2022-03-15 Phynexus, Inc. Devices and methods for plasmid purification
AU2012242510B2 (en) 2011-04-15 2015-05-14 Becton, Dickinson And Company Scanning real-time microfluidic thermocycler and methods for synchronized thermocycling and scanning optical detection
JP6117217B2 (ja) 2011-09-30 2017-04-19 ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company ユニット化された試薬ストリップ
USD692162S1 (en) 2011-09-30 2013-10-22 Becton, Dickinson And Company Single piece reagent holder
EP2773892B1 (de) 2011-11-04 2020-10-07 Handylab, Inc. Vorrichtung zur vorbereitung von polynukleotidproben
ES2978107T3 (es) 2012-02-03 2024-09-05 Becton Dickinson Co Archivos externos para distribución de pruebas de diagnóstico molecular y determinación de compatibilidad entre pruebas
DE102012015063B4 (de) * 2012-07-31 2014-10-30 Sartorius Stedim Biotech Gmbh Vorrichtung und Verfahren zur Behandlung eines Filtrationsmediums
IN2015DN02055A (de) 2012-09-17 2015-08-14 Grace W R & Co
US9624487B2 (en) * 2012-11-02 2017-04-18 California Institute Of Technology Methods and apparatuses for nucleic acid purification
US9920294B2 (en) 2013-02-15 2018-03-20 Douglas T. Gjerde Devices and methods for purification, detection and use of biological cells
WO2015069890A1 (en) 2013-11-06 2015-05-14 The Charles Stark Draper Laboratory, Inc. Systems and method for high-throughput testing
US9592458B2 (en) 2013-12-26 2017-03-14 Dionex Corporation Ion exchange foams to remove ions from samples
EP3092077B1 (de) 2014-01-06 2020-07-29 Omni International, Inc. Homogenisierungsröhren mit strömungsunterbrechern für wulstlosen unterbrochenen fluss
ES2929099T3 (es) 2014-05-02 2022-11-24 Grace W R & Co Material de soporte funcionalizado y métodos de fabricación y uso de material de soporte funcionalizado
EP3146331B1 (de) * 2014-05-20 2021-02-17 Tecan SP, Inc. Probenextraktionsvorrichtung mit mikroelutionsbettkonzept
US10495614B2 (en) 2014-12-30 2019-12-03 Dionex Corporation Vial cap and method for removing matrix components from a liquid sample
JP2018511036A (ja) 2015-01-31 2018-04-19 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft メソダイセクションのためのシステムおよび方法
WO2016120434A1 (en) 2015-01-31 2016-08-04 Roche Diagnostics Gmbh Systems and methods for meso-dissection
ES2896897T3 (es) 2015-06-05 2022-02-28 Grace W R & Co Agentes de clarificación para el bioprocesamiento de adsorbentes y métodos para producir y usar los mismos
US9696284B2 (en) 2015-06-10 2017-07-04 Thermo Fisher Scientific Oy Extraction column
US10849600B2 (en) 2016-03-08 2020-12-01 Entech Instruments Inc. Breath condensate and saliva analysis using oral rinse
US10502664B2 (en) 2016-03-08 2019-12-10 Entech Instruments Inc. Vacuum-assisted sample extraction device and method
JP7059295B2 (ja) 2016-11-09 2022-04-25 エフ.ホフマン-ラ ロシュ アーゲー 自動化された組織ダイセクション機器、およびそれを用いる方法
WO2019173501A1 (en) 2018-03-06 2019-09-12 Entech Instruments Inc. Ventilator-coupled sampling device and method
JP7418412B2 (ja) * 2018-04-30 2024-01-19 フィネクサス・インコーポレイテッド タンパク質の定性分析
CN112513630B (zh) 2018-07-31 2023-05-12 因泰科设备股份有限公司 混合毛细管/填充捕集器及使用方法
WO2020086898A1 (en) 2018-10-25 2020-04-30 Gjerde Douglas T Columns and methods of use for analytical standards and compounds
US12269012B2 (en) 2018-10-25 2025-04-08 Thomas Jakschitz Columns and methods of use for analytical standards and compounds
EP3719493A1 (de) * 2019-04-05 2020-10-07 Biotage AB Verfahren und vorrichtung zur probenvorbereitung
GB201909274D0 (en) * 2019-06-27 2019-08-14 Ge Healthcare Bio Sciences Ab Method in bioprocess purification system
CN115552215A (zh) 2020-05-08 2022-12-30 沃特世科技公司 用于热辅助酶消化的方法
US12411064B2 (en) 2020-05-08 2025-09-09 Waters Technologies Corporation Methods for heat-assisted enzyme digestion
US12560581B2 (en) 2020-08-11 2026-02-24 Entech Instruments Inc. System and method of matrix accelerated vacuum-assisted sorbent extraction for improved sample preparation prior to GCMS analysis
WO2022076543A1 (en) * 2020-10-06 2022-04-14 Phynexus, Inc. Separation device and method of separation
EP3981512A1 (de) 2020-10-06 2022-04-13 Phynexus, Inc. Trennvorrichtung und verfahren zur trennung
GB2616583B (en) * 2020-12-21 2025-08-13 T Gjerde Douglas Piston Pump Syringe Column Method and Device
EP4206324A1 (de) 2022-01-04 2023-07-05 Phynexus, Inc. Reinigung von makromolekülen
CN115078610B (zh) * 2022-07-22 2025-02-07 郑州大学第一附属医院 一种检测体液中疏水性药物含量的方法

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4131544A (en) 1976-08-03 1978-12-26 Nasik Elahi Macroencapsulated sorbent element and process for using the same
IL51668A (en) * 1977-03-16 1981-12-31 Israel State Analytical method for the quantitative determination of immunogens and antibodies and a kit therefor
DE2933015A1 (de) * 1979-08-16 1981-03-26 Behringwerke AG, 35041 Marburg Verfahren zur herstellung der dritten komponente des komplements aus menschlichem blutplasma
US5187990A (en) 1984-02-16 1993-02-23 Rainin Instrument Co., Inc. Method for dispensing liquids with a pipette with compensation for air pressure and surface tension
JPS6190705A (ja) * 1984-10-09 1986-05-08 Terumo Corp 中空糸膜の製造方法
DE3717211A1 (de) 1987-05-22 1988-12-01 Diagen Inst Molekularbio Vorrichtung und verfahren zur trennung und reinigung von molekuelen
US5219529A (en) * 1987-07-07 1993-06-15 Unisyn Technologies, Inc. Cartridge assembly
US5437979A (en) 1989-07-24 1995-08-01 Beckman Instruments, Inc. Solid phase system for sequential reactions
US5443734A (en) 1990-03-05 1995-08-22 Applied Separations, Inc. Programmable solid phase extraction and elution device
US5171537A (en) 1991-05-06 1992-12-15 Richard E. MacDonald Activated immunodiagnostic pipette tips
DE69305947T2 (de) 1992-09-18 1997-03-13 Amersham Int Plc Vorrichtung und Methode zur Affinitätstrennung
US5368729A (en) * 1993-07-23 1994-11-29 Whatman, Inc. Solid phase extraction device
US5547833A (en) * 1994-01-04 1996-08-20 Intracel Corporation Radial flow assay, delivering member, test kit, and methods
DE4432654C2 (de) * 1994-09-14 1998-03-26 Qiagen Gmbh Verfahren zur Isolierung von Nukleinsäuren aus natürlichen Quellen
US5595653A (en) 1994-07-15 1997-01-21 Cera, Inc. Microcolumn for extraction of analytes from liquids
US5556589A (en) * 1994-09-07 1996-09-17 Hercules Incorporated Process of using a spin pack for multicomponent fibers
US6117394A (en) 1996-04-10 2000-09-12 Smith; James C. Membrane filtered pipette tip
US6048457A (en) 1997-02-26 2000-04-11 Millipore Corporation Cast membrane structures for sample preparation
US5849249A (en) 1997-03-17 1998-12-15 Whatman Inc. Solid phase extraction apparatus for enhanced recovery and precision
US5863428A (en) * 1997-04-01 1999-01-26 Phenomenex Guard cartridge for chromatography
US6045757A (en) 1997-06-30 2000-04-04 Rainin Instrument Co., Inc. Membrane filter pipette tip
US6139733A (en) * 1998-08-20 2000-10-31 Dyax Corporation Module and method for introducing a sample into a chromatography column
CZ9900769A3 (cs) 1999-03-04 2000-10-11 Petr Ing. Drsc. Hušek Použití špičky s filtrem k vytvoření sloupce sorbentu s definovaným objemem v prostoru pod filtrem
JP2006509994A (ja) 1999-07-26 2006-03-23 ハーバード アパラタス インコーポレーティッド 試料を調製するための表面被覆ハウジング
JP4346754B2 (ja) 1999-10-26 2009-10-21 日東電工株式会社 ピペット用フィルターの製作方法
US6566145B2 (en) 2000-02-09 2003-05-20 William E Brewer Disposable pipette extraction
JP2001281117A (ja) 2000-03-24 2001-10-10 Millipore Corp 試料調製装置及び試料調製装置形成方法
US6416716B1 (en) 2001-04-20 2002-07-09 Ashok Kumar Shukla Sample preparation device with embedded separation media
US6527951B1 (en) * 2000-11-16 2003-03-04 Waters Investments Limited Chromatographic column
US20020110495A1 (en) 2001-01-05 2002-08-15 Denis Hunt Devices and methods for purification
US20030007897A1 (en) 2001-07-06 2003-01-09 Andrew Creasey Pipette tips
WO2003050540A2 (en) * 2001-12-05 2003-06-19 Large Scale Biology Corporation Flexible method and apparatus for high throughput production and purification of multiple proteins
US6723236B2 (en) * 2002-03-19 2004-04-20 Waters Investments Limited Device for solid phase extraction and method for purifying samples prior to analysis

Also Published As

Publication number Publication date
JP2006515562A (ja) 2006-06-01
EP1521637B1 (de) 2011-10-19
US7482169B2 (en) 2009-01-27
EP1521637A1 (de) 2005-04-13
AU2003249231A1 (en) 2004-02-02
WO2004007081A1 (en) 2004-01-22
US20040072375A1 (en) 2004-04-15

Similar Documents

Publication Publication Date Title
ATE529188T1 (de) Extraktionskolonnenvorrichtung
Guzman et al. The use of selective adsorbents in capillary electrophoresis‐mass spectrometry for analyte preconcentration and microreactions: A powerful three‐dimensional tool for multiple chemical and biological applications
Wang et al. Development of an extraction method and LC–MS analysis for N-acylated-l-homoserine lactones (AHLs) in wastewater treatment biofilms
Zou et al. Affinity membrane chromatography for the analysis and purification of proteins
US8753897B2 (en) Nanoporous substrates for the analytical methods
Pena-Pereira et al. Greening sample preparation: an overview of cutting-edge contributions
Boos et al. Multidimensional on-line solid-phase extraction (SPE) using restricted access materials (RAM) in combination with molecular imprinted polymers (MIP)
WO2008060784A3 (en) System for rapid analysis of glycated proteinaceous species in biological samples
WO2006110644A3 (en) Improved methods and devices for concentration and fractionation of analytes for chemical analysis including matrix-assisted laser desorption/ionization (maldi) mass spectrometry (ms)
Vu et al. Clinical screening of paraquat in plasma samples using capillary electrophoresis with contactless conductivity detection: towards rapid diagnosis and therapeutic treatment of acute paraquat poisoning in Vietnam
CA2354379A1 (en) Method for isolating dna from biological materials
WO2007041692A3 (en) Microfluidic detection of analytes
EA201071134A1 (ru) Анализ днк посредством капиллярного электрофореза
ATE420348T1 (de) Vorrichtung zur probenvorbereitung
CN110806451B (zh) 一种测定血浆中OPEs的磷酸二酯代谢物含量的方法
ATE434764T1 (de) Verfahren zur bestimmung der konzentration von asymmetrischem dimethylarginin (adma)
Pederson-Bjergaard et al. High-throughput liquid–liquid extraction in 96-well format: parallel artificial liquid membrane extraction
DE60327583D1 (de) Methode zur Trennung und Aufreinigung von Nukleinsäuren
JP5273658B2 (ja) リン酸化ペプチド又はリン酸化タンパク質の分離方法
RU2205398C1 (ru) Способ определения гидрохинона и пирокатехина в водных растворах
Plotnikov et al. Determination of codeine phosphate in the culture fluid of Rhodococcus by high-performance liquid chromatography
Williams et al. Rapid determination of rat plasma uridine levels by HPLC‐ESI‐MS utilizing the Captiva™ filter plates for sample preparation
He Microextraction and its application to forensic toxicology analysis
Cappiello et al. Advances in the Use of Liquid Chromatography Mass Spectrometry (LC-MS): Instrumentation Developments and Applications
Carr The role of chromatography in the characterization and analysis of protein therapeutic drugs

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties