ATE526995T1 - Stereoisomers von fettsäureanalogen für diagnostische bildgebung - Google Patents

Stereoisomers von fettsäureanalogen für diagnostische bildgebung

Info

Publication number
ATE526995T1
ATE526995T1 AT06025944T AT06025944T ATE526995T1 AT E526995 T1 ATE526995 T1 AT E526995T1 AT 06025944 T AT06025944 T AT 06025944T AT 06025944 T AT06025944 T AT 06025944T AT E526995 T1 ATE526995 T1 AT E526995T1
Authority
AT
Austria
Prior art keywords
stereoisomers
fatty acid
diagnostic imaging
acid analogues
imaging agents
Prior art date
Application number
AT06025944T
Other languages
German (de)
English (en)
Inventor
David R Elmaleh
Original Assignee
Molecular Insight Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Molecular Insight Pharm Inc filed Critical Molecular Insight Pharm Inc
Application granted granted Critical
Publication of ATE526995T1 publication Critical patent/ATE526995T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0402—Organic compounds carboxylic acid carriers, fatty acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fats And Perfumes (AREA)
  • Nuclear Medicine (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT06025944T 1995-12-01 1996-11-25 Stereoisomers von fettsäureanalogen für diagnostische bildgebung ATE526995T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US786395P 1995-12-01 1995-12-01

Publications (1)

Publication Number Publication Date
ATE526995T1 true ATE526995T1 (de) 2011-10-15

Family

ID=21728502

Family Applications (2)

Application Number Title Priority Date Filing Date
AT06025944T ATE526995T1 (de) 1995-12-01 1996-11-25 Stereoisomers von fettsäureanalogen für diagnostische bildgebung
AT96941503T ATE353019T1 (de) 1995-12-01 1996-11-25 Stereoisomere von fettsäureanalogen zur diagnostischen bildgebung

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT96941503T ATE353019T1 (de) 1995-12-01 1996-11-25 Stereoisomere von fettsäureanalogen zur diagnostischen bildgebung

Country Status (8)

Country Link
US (4) US7005119B2 (enExample)
EP (2) EP1767224B1 (enExample)
JP (3) JP4272259B2 (enExample)
AT (2) ATE526995T1 (enExample)
CA (1) CA2238860C (enExample)
DE (1) DE69636881T2 (enExample)
ES (2) ES2281906T3 (enExample)
WO (1) WO1997019705A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997019705A1 (en) * 1995-12-01 1997-06-05 Elmaleh David R Stereoisomers of fatty acid analogs for diagnostic imaging
US20090117032A1 (en) * 1998-09-08 2009-05-07 The General Hospital Corporation Imaging Agents for Early Detection and Monitoring of Cardiovascular Plaque
EP0992245A1 (en) * 1998-09-16 2000-04-12 Goldham Bioglan Pharma GmbH Radio-contrast agents
EP1040825A1 (en) * 1999-03-11 2000-10-04 K.U. Leuven Research & Development Means for diagnosing bladder carcinoma
DE60030270T2 (de) * 1999-04-14 2007-08-30 Molecular Insight Pharmaceuticals, Inc., Cambridge Fettsaure analoge zur diagnose von kranzarterie erkrankungen
JP4951798B2 (ja) 2002-04-01 2012-06-13 モレキュラ インサイト ファーマシューティカルズ インコーポレイテッド 側基脂肪酸撮像剤
WO2004093650A2 (en) 2003-04-17 2004-11-04 The General Hospital Corporation Method for monitoring blood flow and metabolic uptake in tissue with radiolabeled alkanoic acid
JP2012526129A (ja) * 2009-05-04 2012-10-25 ワシントン・ユニバーシティ 脂肪酸代謝および貯蔵を画像化するためのｐｅｔ放射性追跡子
DE102010010666A1 (de) * 2010-03-01 2011-09-01 Sven Reske Diagnose und Therapie von Krebserkrankungen mittels Fettsäuren

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6802651A (enExample) * 1968-02-23 1969-08-26
DE2828623C2 (de) * 1978-06-29 1983-11-17 Kernforschungsanlage Jülich GmbH, 5170 Jülich Mit radioaktivem Flour markierte C↓1↓↓6↓-bis C↓1↓↓8↓- Fettsäuren, ein Verfahren zu ihrer Herstellung sowie deren Verwendung
DE2947500C2 (de) * 1979-11-24 1984-05-10 Dutschka, Klaus, 4300 Essen Radiojodierte ω -Phenylfettsäuren, ihre Herstellung und deren Verwendung zur szintigraphischen Untersuchung des Herzmuskels und der Leber
FR2508902B1 (fr) * 1981-07-02 1985-09-06 Commissariat Energie Atomique Procede de preparation extemporanee d'un acide gras injectable, marque a l'iode radioactif et preparation de derives iodes utilisables pour la mise en oeuvre de ce procede
US4524059A (en) * 1983-01-28 1985-06-18 The General Hospital Corporation Fatty acid analogs
US4942231A (en) * 1984-05-24 1990-07-17 Mallinckrodt, Inc. Method of preparing a chlorinated, brominated, radio-brominated, iodinated and/or radioiodinated aromatic or heteroaromatic compound
EP0194843B1 (en) * 1985-03-11 1993-01-13 AMERSHAM INTERNATIONAL plc Complexes of technetium-99m with propylene amine oximes
US4746505A (en) * 1985-04-26 1988-05-24 President And Fellows Of Harvard College Technetium radiodiagnostic fatty acids derived from bisamide bisthiol ligands
US4764358A (en) * 1985-04-30 1988-08-16 The United States Of America As Represented By The United States Department Of Energy Radiolabeled dimethyl branched long chain fatty acid for heart imaging
US4877599A (en) * 1986-11-10 1989-10-31 New England Deaconess Hospital Corporation Detection of vascular disease with labelled antibodies
DE3880974T2 (de) * 1987-11-19 1993-08-26 Univ Vanderbilt Radiojodhaltige benzamide und verfahren zu ihrer verwendung als radiobildende agenzien.
US5242681A (en) * 1990-03-12 1993-09-07 Research Corporation Technologies, Inc. Lipophilic contrast agents for diagnostic image analysis
US7238340B1 (en) * 1991-11-27 2007-07-03 Cis Bio International Monoamine, diamide, thiol-containing metal chelating agents
WO1997019705A1 (en) * 1995-12-01 1997-06-05 Elmaleh David R Stereoisomers of fatty acid analogs for diagnostic imaging
EP2324857A1 (en) * 1997-09-08 2011-05-25 The General Hospital Corporation Imaging agents for early detection of cardiovascular plaque
US7060251B1 (en) * 1997-09-08 2006-06-13 The General Hospital Corporation Imaging agents for early detection and monitoring of cardiovascular plaque
DE60030270T2 (de) * 1999-04-14 2007-08-30 Molecular Insight Pharmaceuticals, Inc., Cambridge Fettsaure analoge zur diagnose von kranzarterie erkrankungen
AU2001245862A1 (en) * 2000-03-21 2001-10-03 The Procter & Gamble Company Difluorobutyric acid metalloprotease inhibitors
WO2004093650A2 (en) * 2003-04-17 2004-11-04 The General Hospital Corporation Method for monitoring blood flow and metabolic uptake in tissue with radiolabeled alkanoic acid

Also Published As

Publication number Publication date
JP2012036215A (ja) 2012-02-23
ATE353019T1 (de) 2007-02-15
US20030215386A1 (en) 2003-11-20
CA2238860C (en) 2009-01-13
US20070128110A1 (en) 2007-06-07
JP4272259B2 (ja) 2009-06-03
ES2281906T3 (es) 2007-10-01
US7314609B2 (en) 2008-01-01
EP1767224B1 (en) 2011-10-05
EP0869821A4 (en) 2002-08-28
US20080247948A1 (en) 2008-10-09
EP1767224A2 (en) 2007-03-28
ES2374743T3 (es) 2012-02-21
HK1102262A1 (en) 2007-11-09
EP0869821B1 (en) 2007-01-31
JP2008201774A (ja) 2008-09-04
JP2000502059A (ja) 2000-02-22
CA2238860A1 (en) 1997-06-05
DE69636881T2 (de) 2007-09-20
US20060078495A1 (en) 2006-04-13
JP4937144B2 (ja) 2012-05-23
EP0869821A1 (en) 1998-10-14
US7005119B2 (en) 2006-02-28
HK1016494A1 (en) 1999-11-05
WO1997019705A1 (en) 1997-06-05
DE69636881D1 (de) 2007-03-22
EP1767224A3 (en) 2007-11-28

Similar Documents

Publication Publication Date Title
IT8421982A0 (it) Strumento per l'estrazione di corpi estranei da canali fisiologici dell'organismo.
ATE108666T1 (de) Ultraschall-kontrastmittel, verfahren zu ihrer herstellung und verwendung derselben als diagnostika und therapeutika.
DE19775096I2 (de) Desulfatohirudine Verfahren zu ihrer Herstellung und pharmazeutische Mittel
DE3577185D1 (de) Paramagnetische kontrastmittel fuer die anwendung in "in vivo" nmr-diagnostischen methoden und die herstellung davon.
AU5292290A (en) Diagnostic method for alzheimer's disease: examination of non-neural tissue
AU5672194A (en) Apparatus for diagnostic imaging
FR10C0016I2 (fr) Procedes et compositions s'appliquant au traitement de la glomerulonephrite
ATE411026T1 (de) Mittel zur behandlung der alzheimer-krankheit
ATE526995T1 (de) Stereoisomers von fettsäureanalogen für diagnostische bildgebung
ATE230416T1 (de) Neue mittel zur diagnose von gefässerkrankungen
EP0757696A4 (en) DIAGNOSIS OF HUMAN SPERM
DE69434777D1 (de) Verwendung von Relaxin zur Herstellung von therapeutischen Mitteln
ATE258933T1 (de) Übergangszustand-analoga des kokains, ihre verwendung zur herstellung von kataltischen antikörpern gegen kokain und verwendung derselben in diagnose und therapie
DE69527366D1 (de) Enzymatische zusammensetzung fur die klinische untersuchung
DE69637449D1 (de) Verwendung von alpha-hydroxysäuren zur herstellung eines arzneimittels für die behandlung von entzündungen
DE69533876D1 (de) Zusammensetzung für die gentherapeutische Behandlung von Koronar-Arterienerkrankungen.
AU2579995A (en) Alpha b crystallin for use in diagnosis and therapy of auto-immune diseases in particular multiple sclerosis
NO175745C (no) Analogifremgangsmåte for fremstilling av dibenzo(1,5)-dioksocin-5-oner
FR2737732B1 (fr) Test co-dominant de diagnostic genetique
EP0280135A3 (en) Protein c-inhibitor (pci) as a pharmaceutical and diagnostic agent, process for the preparation of such a pharmaceutical or diagnostic agent and a composition containing pci
ATE337020T1 (de) Fettsaure analoge zur diagnose von kranzarterie erkrankungen
HUP0000177A3 (en) Diagnosis of diseases associated with coronary twitching
ES2151572T3 (es) Benzoilguanidinas sustituidas con trifluoropropilo y su empleo como medicamento o agente de diagnostico.
IL114548A0 (en) Complex compounds for diagnosis of vascular diseases
DE3881698D1 (de) Lectine, die beta-d-galactosid binden.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties