ES2151572T3 - Benzoilguanidinas sustituidas con trifluoropropilo y su empleo como medicamento o agente de diagnostico. - Google Patents
Benzoilguanidinas sustituidas con trifluoropropilo y su empleo como medicamento o agente de diagnostico.Info
- Publication number
- ES2151572T3 ES2151572T3 ES95113846T ES95113846T ES2151572T3 ES 2151572 T3 ES2151572 T3 ES 2151572T3 ES 95113846 T ES95113846 T ES 95113846T ES 95113846 T ES95113846 T ES 95113846T ES 2151572 T3 ES2151572 T3 ES 2151572T3
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- cycloalkyl
- replaced
- opt
- trifluoropropilo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
- C07C317/46—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Neurosurgery (AREA)
- Emergency Medicine (AREA)
- Surgery (AREA)
- Reproductive Health (AREA)
- Vascular Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
SE DESCRIBEN BENZOILGUANIDINAS DE LA FORMULA I CON LAS DEFINICIONES DE R(1) HASTA R(4) DADAS EN EL TEXTO ASI COMO SUS SALES TOLERABLES FISIOLOGICAMENTE. SE OBTIENEN MEDIANTE TRANSFORMACION DE UN COMPUESTO II CON GUANIDINA. SON AGENTES SOBRESALIENTES PARA TRATAMIENTO DE ENFERMEDADES DEL SISTEMA DEL CICLO CARDIACO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4432105A DE4432105A1 (de) | 1994-09-09 | 1994-09-09 | Fluoro-alkyl/alkenyl-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2151572T3 true ES2151572T3 (es) | 2001-01-01 |
Family
ID=6527787
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES95113846T Expired - Lifetime ES2151572T3 (es) | 1994-09-09 | 1995-09-04 | Benzoilguanidinas sustituidas con trifluoropropilo y su empleo como medicamento o agente de diagnostico. |
Country Status (24)
Country | Link |
---|---|
US (2) | US5869531A (es) |
EP (1) | EP0702001B1 (es) |
JP (1) | JPH0899950A (es) |
KR (1) | KR960010620A (es) |
CN (1) | CN1063436C (es) |
AT (1) | ATE195725T1 (es) |
AU (1) | AU698629B2 (es) |
CA (1) | CA2157856C (es) |
CZ (1) | CZ290027B6 (es) |
DE (2) | DE4432105A1 (es) |
DK (1) | DK0702001T3 (es) |
ES (1) | ES2151572T3 (es) |
FI (1) | FI954191A (es) |
GR (1) | GR3034512T3 (es) |
HU (1) | HU221851B1 (es) |
IL (1) | IL115194A (es) |
NO (2) | NO305117B1 (es) |
NZ (1) | NZ272948A (es) |
PL (1) | PL181206B1 (es) |
PT (1) | PT702001E (es) |
RU (1) | RU2159762C2 (es) |
SI (1) | SI9500281B (es) |
TW (1) | TW382621B (es) |
ZA (1) | ZA957549B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19540995A1 (de) * | 1995-11-03 | 1997-05-07 | Hoechst Ag | Substituierte Sulfonimidamide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
DE19542306A1 (de) * | 1995-11-14 | 1997-05-15 | Hoechst Ag | Sulfonylamino-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
PL316439A1 (en) * | 1995-11-20 | 1997-05-26 | Hoechst Ag | Novel substituted derivatives of benzoyloguanidine, method of obtaining them, their application in production of pharmaceutic and diagnostic agents and pharmaceutic agent as such |
DE19546736A1 (de) * | 1995-12-14 | 1997-06-19 | Hoechst Ag | Substituierte Chromanylsulfonyl(thio)harnstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung pharmazeutischer Präparate |
JP4745432B2 (ja) * | 2009-09-30 | 2011-08-10 | 住友大阪セメント株式会社 | 光導波路素子 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3780027A (en) * | 1970-04-29 | 1973-12-18 | Merck & Co Inc | Anthranilic acid derivatives |
DE3929582A1 (de) * | 1989-09-06 | 1991-03-07 | Hoechst Ag | Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament |
ATE139526T1 (de) * | 1992-02-15 | 1996-07-15 | Hoechst Ag | 3,5-substituierte benzoylguanidine, mit antiarrythmischer wirkung und inhibierender wirkung auf die proliferationen von zellen |
DE4237035A1 (de) * | 1992-11-03 | 1994-05-05 | Vorwerk Co Interholding | Staubfilterbeutel für einen Staubsauger |
TW250477B (es) * | 1992-12-15 | 1995-07-01 | Hoechst Ag | |
EP0604852A1 (de) * | 1992-12-28 | 1994-07-06 | Hoechst Aktiengesellschaft | 2,4-Substituierte 5-(N-substituierte-Sulfamoyl)-Benzoylguanidine, als Antiarrythmika, Inhibitoren der Proliferationen von Zellen, und Inhibitoren des Natrium-Protonen-Antiporters |
DK0612723T3 (da) * | 1993-02-20 | 1998-03-30 | Hoechst Ag | Substituerede benzoylguanidiner, fremgangsmåde til fremstilling, deres anvendelse som lægemiddel, som inhibitor af den cellulære Na+/H+-udbytning eller som diagnostikum samt lægemiddel med indhold deraf |
-
1994
- 1994-09-09 DE DE4432105A patent/DE4432105A1/de not_active Withdrawn
-
1995
- 1995-02-16 TW TW084101385A patent/TW382621B/zh not_active IP Right Cessation
- 1995-09-04 DE DE59508654T patent/DE59508654D1/de not_active Expired - Lifetime
- 1995-09-04 ES ES95113846T patent/ES2151572T3/es not_active Expired - Lifetime
- 1995-09-04 EP EP95113846A patent/EP0702001B1/de not_active Expired - Lifetime
- 1995-09-04 DK DK95113846T patent/DK0702001T3/da active
- 1995-09-04 AT AT95113846T patent/ATE195725T1/de not_active IP Right Cessation
- 1995-09-04 PT PT95113846T patent/PT702001E/pt unknown
- 1995-09-06 IL IL11519495A patent/IL115194A/xx not_active IP Right Cessation
- 1995-09-06 CN CN95116262A patent/CN1063436C/zh not_active Expired - Fee Related
- 1995-09-07 RU RU95115408/04A patent/RU2159762C2/ru not_active IP Right Cessation
- 1995-09-07 NZ NZ272948A patent/NZ272948A/en unknown
- 1995-09-07 AU AU30505/95A patent/AU698629B2/en not_active Ceased
- 1995-09-07 KR KR1019950029357A patent/KR960010620A/ko not_active Application Discontinuation
- 1995-09-07 FI FI954191A patent/FI954191A/fi unknown
- 1995-09-08 CZ CZ19952316A patent/CZ290027B6/cs not_active IP Right Cessation
- 1995-09-08 CA CA002157856A patent/CA2157856C/en not_active Expired - Fee Related
- 1995-09-08 US US08/525,095 patent/US5869531A/en not_active Expired - Lifetime
- 1995-09-08 JP JP7230967A patent/JPH0899950A/ja active Pending
- 1995-09-08 SI SI9500281A patent/SI9500281B/sl unknown
- 1995-09-08 PL PL95310345A patent/PL181206B1/pl unknown
- 1995-09-08 HU HU9502633A patent/HU221851B1/hu not_active IP Right Cessation
- 1995-09-08 NO NO953554A patent/NO305117B1/no unknown
- 1995-09-08 ZA ZA957549A patent/ZA957549B/xx unknown
-
1998
- 1998-02-24 US US09/028,920 patent/US5998481A/en not_active Expired - Lifetime
- 1998-11-10 NO NO985244A patent/NO306293B1/no unknown
-
2000
- 2000-09-29 GR GR20000402202T patent/GR3034512T3/el not_active IP Right Cessation
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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