ATE353019T1 - Stereoisomere von fettsäureanalogen zur diagnostischen bildgebung - Google Patents

Stereoisomere von fettsäureanalogen zur diagnostischen bildgebung

Info

Publication number
ATE353019T1
ATE353019T1 AT96941503T AT96941503T ATE353019T1 AT E353019 T1 ATE353019 T1 AT E353019T1 AT 96941503 T AT96941503 T AT 96941503T AT 96941503 T AT96941503 T AT 96941503T AT E353019 T1 ATE353019 T1 AT E353019T1
Authority
AT
Austria
Prior art keywords
stereoisomers
fatty acid
diagnostic imaging
acid analogues
imaging agents
Prior art date
Application number
AT96941503T
Other languages
English (en)
Inventor
David R Elmaleh
Original Assignee
Molecular Insight Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Molecular Insight Pharm Inc filed Critical Molecular Insight Pharm Inc
Application granted granted Critical
Publication of ATE353019T1 publication Critical patent/ATE353019T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0402—Organic compounds carboxylic acid carriers, fatty acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fats And Perfumes (AREA)
  • Nuclear Medicine (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT96941503T 1995-12-01 1996-11-25 Stereoisomere von fettsäureanalogen zur diagnostischen bildgebung ATE353019T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US786395P 1995-12-01 1995-12-01

Publications (1)

Publication Number Publication Date
ATE353019T1 true ATE353019T1 (de) 2007-02-15

Family

ID=21728502

Family Applications (2)

Application Number Title Priority Date Filing Date
AT96941503T ATE353019T1 (de) 1995-12-01 1996-11-25 Stereoisomere von fettsäureanalogen zur diagnostischen bildgebung
AT06025944T ATE526995T1 (de) 1995-12-01 1996-11-25 Stereoisomers von fettsäureanalogen für diagnostische bildgebung

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT06025944T ATE526995T1 (de) 1995-12-01 1996-11-25 Stereoisomers von fettsäureanalogen für diagnostische bildgebung

Country Status (9)

Country Link
US (4) US7005119B2 (de)
EP (2) EP1767224B1 (de)
JP (3) JP4272259B2 (de)
AT (2) ATE353019T1 (de)
CA (1) CA2238860C (de)
DE (1) DE69636881T2 (de)
ES (2) ES2281906T3 (de)
HK (2) HK1016494A1 (de)
WO (1) WO1997019705A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE353019T1 (de) * 1995-12-01 2007-02-15 Molecular Insight Pharm Inc Stereoisomere von fettsäureanalogen zur diagnostischen bildgebung
US20090117032A1 (en) * 1998-09-08 2009-05-07 The General Hospital Corporation Imaging Agents for Early Detection and Monitoring of Cardiovascular Plaque
EP0992245A1 (de) * 1998-09-16 2000-04-12 Goldham Bioglan Pharma GmbH Radiokontrastmitteln
EP1040825A1 (de) * 1999-03-11 2000-10-04 K.U. Leuven Research & Development Mittel zur Diagnostik von Harnblasenkarzinom
US6437103B1 (en) 1999-04-14 2002-08-20 Biostream Inc. Fatty acid analogs for diagnosis of coronary artery disease
JP4951798B2 (ja) * 2002-04-01 2012-06-13 モレキュラ インサイト ファーマシューティカルズ インコーポレイテッド 側基脂肪酸撮像剤
WO2004093650A2 (en) 2003-04-17 2004-11-04 The General Hospital Corporation Method for monitoring blood flow and metabolic uptake in tissue with radiolabeled alkanoic acid
US20120100073A1 (en) * 2009-05-04 2012-04-26 Washington University Pet radiotracers for imaging fatty acid metabolism and storage
DE102010010666A1 (de) * 2010-03-01 2011-09-01 Sven Reske Diagnose und Therapie von Krebserkrankungen mittels Fettsäuren

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6802651A (de) * 1968-02-23 1969-08-26
DE2828623C2 (de) * 1978-06-29 1983-11-17 Kernforschungsanlage Jülich GmbH, 5170 Jülich Mit radioaktivem Flour markierte C↓1↓↓6↓-bis C↓1↓↓8↓- Fettsäuren, ein Verfahren zu ihrer Herstellung sowie deren Verwendung
DE2947500C2 (de) * 1979-11-24 1984-05-10 Dutschka, Klaus, 4300 Essen Radiojodierte ω -Phenylfettsäuren, ihre Herstellung und deren Verwendung zur szintigraphischen Untersuchung des Herzmuskels und der Leber
FR2508902B1 (fr) * 1981-07-02 1985-09-06 Commissariat Energie Atomique Procede de preparation extemporanee d'un acide gras injectable, marque a l'iode radioactif et preparation de derives iodes utilisables pour la mise en oeuvre de ce procede
US4524059A (en) * 1983-01-28 1985-06-18 The General Hospital Corporation Fatty acid analogs
US4942231A (en) * 1984-05-24 1990-07-17 Mallinckrodt, Inc. Method of preparing a chlorinated, brominated, radio-brominated, iodinated and/or radioiodinated aromatic or heteroaromatic compound
DE3687467T2 (de) * 1985-03-11 1993-04-29 Amersham Int Plc Komplexe von technetium-99m mit propylen-amin-oximen.
US4746505A (en) * 1985-04-26 1988-05-24 President And Fellows Of Harvard College Technetium radiodiagnostic fatty acids derived from bisamide bisthiol ligands
US4764358A (en) * 1985-04-30 1988-08-16 The United States Of America As Represented By The United States Department Of Energy Radiolabeled dimethyl branched long chain fatty acid for heart imaging
US4877599A (en) 1986-11-10 1989-10-31 New England Deaconess Hospital Corporation Detection of vascular disease with labelled antibodies
EP0317873B1 (de) * 1987-11-19 1993-05-12 The Vanderbilt University Radiojodhaltige Benzamide und Verfahren zu ihrer Verwendung als radiobildende Agenzien
US5242681A (en) * 1990-03-12 1993-09-07 Research Corporation Technologies, Inc. Lipophilic contrast agents for diagnostic image analysis
US7238340B1 (en) * 1991-11-27 2007-07-03 Cis Bio International Monoamine, diamide, thiol-containing metal chelating agents
ATE353019T1 (de) * 1995-12-01 2007-02-15 Molecular Insight Pharm Inc Stereoisomere von fettsäureanalogen zur diagnostischen bildgebung
CA2302837A1 (en) * 1997-09-08 1999-03-18 The General Hospital Corporation Imaging agents for early detection and monitoring of cardiovascular plaque
US7060251B1 (en) * 1997-09-08 2006-06-13 The General Hospital Corporation Imaging agents for early detection and monitoring of cardiovascular plaque
US6437103B1 (en) * 1999-04-14 2002-08-20 Biostream Inc. Fatty acid analogs for diagnosis of coronary artery disease
JP2003528082A (ja) * 2000-03-21 2003-09-24 ザ プロクター アンド ギャンブル カンパニー ニフッ化酪酸メタロプロテアーゼ阻害物質
WO2004093650A2 (en) * 2003-04-17 2004-11-04 The General Hospital Corporation Method for monitoring blood flow and metabolic uptake in tissue with radiolabeled alkanoic acid

Also Published As

Publication number Publication date
HK1102262A1 (en) 2007-11-09
JP2008201774A (ja) 2008-09-04
ES2281906T3 (es) 2007-10-01
US20070128110A1 (en) 2007-06-07
EP0869821A1 (de) 1998-10-14
CA2238860A1 (en) 1997-06-05
US7314609B2 (en) 2008-01-01
ATE526995T1 (de) 2011-10-15
US20030215386A1 (en) 2003-11-20
EP0869821B1 (de) 2007-01-31
JP2012036215A (ja) 2012-02-23
ES2374743T3 (es) 2012-02-21
JP4937144B2 (ja) 2012-05-23
DE69636881T2 (de) 2007-09-20
EP1767224B1 (de) 2011-10-05
US7005119B2 (en) 2006-02-28
HK1016494A1 (en) 1999-11-05
CA2238860C (en) 2009-01-13
WO1997019705A1 (en) 1997-06-05
JP2000502059A (ja) 2000-02-22
JP4272259B2 (ja) 2009-06-03
EP1767224A3 (de) 2007-11-28
DE69636881D1 (de) 2007-03-22
EP0869821A4 (de) 2002-08-28
US20060078495A1 (en) 2006-04-13
US20080247948A1 (en) 2008-10-09
EP1767224A2 (de) 2007-03-28

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties