DE69328527D1 - Carboxypeptidase-ähnliches Protein aus Knochen und Verfahren zur dessen Herstellung - Google Patents

Carboxypeptidase-ähnliches Protein aus Knochen und Verfahren zur dessen Herstellung

Info

Publication number
DE69328527D1
DE69328527D1 DE69328527T DE69328527T DE69328527D1 DE 69328527 D1 DE69328527 D1 DE 69328527D1 DE 69328527 T DE69328527 T DE 69328527T DE 69328527 T DE69328527 T DE 69328527T DE 69328527 D1 DE69328527 D1 DE 69328527D1
Authority
DE
Germany
Prior art keywords
bone
protein
carboxypeptidase
osf
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69328527T
Other languages
English (en)
Other versions
DE69328527T2 (de
Inventor
Shinji Kawai
Sunao Takeshita
Makoto Okazaki
Egon Dr Amann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis KK
Aventis Pharmaceuticals Inc
Original Assignee
Nippon Hoechst Marion Roussel Ltd
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Hoechst Marion Roussel Ltd, Hoechst Marion Roussel Inc filed Critical Nippon Hoechst Marion Roussel Ltd
Application granted granted Critical
Publication of DE69328527D1 publication Critical patent/DE69328527D1/de
Publication of DE69328527T2 publication Critical patent/DE69328527T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Woven Fabrics (AREA)
DE69328527T 1992-08-28 1993-08-25 Carboxypeptidase-ähnliches Protein aus Knochen und Verfahren zur dessen Herstellung Expired - Fee Related DE69328527T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP23002992 1992-08-28
JP32403392A JP3472587B2 (ja) 1992-08-28 1992-12-03 骨関連カルボキシペプチダーゼ様タンパク質およびその製造法

Publications (2)

Publication Number Publication Date
DE69328527D1 true DE69328527D1 (de) 2000-06-08
DE69328527T2 DE69328527T2 (de) 2001-01-11

Family

ID=26529108

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69328527T Expired - Fee Related DE69328527T2 (de) 1992-08-28 1993-08-25 Carboxypeptidase-ähnliches Protein aus Knochen und Verfahren zur dessen Herstellung

Country Status (10)

Country Link
US (1) US5460951A (de)
EP (1) EP0588118B1 (de)
JP (1) JP3472587B2 (de)
AT (1) ATE192495T1 (de)
AU (1) AU663217B2 (de)
CA (1) CA2104998A1 (de)
DE (1) DE69328527T2 (de)
DK (1) DK0588118T3 (de)
ES (1) ES2147556T3 (de)
PT (1) PT588118E (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3560252B2 (ja) * 1992-08-28 2004-09-02 アベンティス ファーマ株式会社 骨関連カドヘリン様タンパク質およびその製造法
JPH06121678A (ja) * 1992-08-28 1994-05-06 Hoechst Japan Ltd 骨関連サルファターゼ様タンパク質およびその製造法
JPH06256210A (ja) * 1993-03-10 1994-09-13 Hoechst Japan Ltd 骨関連転写制御因子様タンパク質およびその製造法
IL116696A (en) * 1995-01-25 1999-08-17 Bio Technology General Corp Production of enzymatically active recombinant carboxypeptidase b
US6468766B1 (en) 1996-03-15 2002-10-22 President And Fellows Of Harvard College Aortic carboxypeptidase-like polypeptide
WO1997033900A1 (en) * 1996-03-15 1997-09-18 President And Fellows Of Harvard College E2a-binding protein
WO1998029453A1 (fr) * 1996-12-27 1998-07-09 Mochida Pharmaceutical Co., Ltd. Medicaments diriges vers la membrane cellulaire
US20020137890A1 (en) * 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US6420155B1 (en) * 1999-10-14 2002-07-16 Curagen Corporation Aortic carboxypeptidase-like protein and nucleic acids encoding same
EP1294902B1 (de) * 2000-05-16 2008-08-13 Millennium Pharmaceuticals, Inc. Behandlungsverfahren unter verwendung von 17906 und dessen anwendungen
KR20010000464A (ko) * 2000-10-02 2001-01-05 김철주 골다공증 진단용 단백질칩
AU2003243151A1 (en) * 2002-08-16 2004-03-03 Agensys, Inc. Nucleic acid and corresponding protein entitled 251p5g2 useful in treatment and detection of cancer
JP2007501627A (ja) 2003-08-08 2007-02-01 インタールーキン ジェネティックス インク 骨粗鬆症のための診断法および治療法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06121678A (ja) * 1992-08-28 1994-05-06 Hoechst Japan Ltd 骨関連サルファターゼ様タンパク質およびその製造法
DE4228839A1 (de) * 1992-08-29 1994-03-03 Behringwerke Ag Verfahren zum Nachweis und zur Bestimmung von Mediatoren

Also Published As

Publication number Publication date
ATE192495T1 (de) 2000-05-15
ES2147556T3 (es) 2000-09-16
EP0588118A3 (de) 1995-01-11
DK0588118T3 (da) 2000-10-02
US5460951A (en) 1995-10-24
CA2104998A1 (en) 1994-03-01
JPH06121682A (ja) 1994-05-06
PT588118E (pt) 2000-09-29
DE69328527T2 (de) 2001-01-11
JP3472587B2 (ja) 2003-12-02
EP0588118B1 (de) 2000-05-03
AU4492393A (en) 1994-03-03
EP0588118A2 (de) 1994-03-23
AU663217B2 (en) 1995-09-28

Similar Documents

Publication Publication Date Title
ATE153696T1 (de) Verfahren und desoxyribonukleinsäure zur herstellung von gewebefaktor-protein
DE69328527T2 (de) Carboxypeptidase-ähnliches Protein aus Knochen und Verfahren zur dessen Herstellung
ATE243479T1 (de) Medizinische vorrichtung mit nukleinsäurehaltiger synthetischer oberfläche zur in-vivo induktion seiner endothelialisierung
ATE130365T1 (de) Bakterien transformiert mit expressionsplasmiden, die für den menschlichen neurothrophen wimper faktor (h-cntf) kodieren, ihre verwendung in der herstellung von h-cntf, antikörper gegen h-cntf und die anwendung von h-cntf in medizischer behandlung.
EA200300845A1 (ru) Модифицированные антитела и способы применения
DE3788961D1 (de) Verfahren zur herstellung von polysubstituierten diethylentriaminpentaessigsäuren.
DE69025922D1 (de) Verwendung von nervonsäure und langkettiger fettsäuren zur behandlung demyelinisierender erkrankungen
DE69533176D1 (de) Verwendung von fibroblastwachstumsfaktoren zur stimulierung des knochenwachstums
GR3031509T3 (en) Keratinocyte growth factor (KGF) for its use in method of therapeutic treatment for the human or animal body.
KR950700079A (ko) 이식체-대-숙주 질환을 억제하기 위한 인터루킨-10의 용도(Use of interleukin-10 to suppress graft-vs. -host disease)
DE69331086T2 (de) Protein des Cadherin-Typs aus Knochen und Verfahren zur Herstellung
DE69323465T2 (de) Sulfatase-ähnliches Protein aus Knochen und Verfahren zu dessen Herstellung
DE69133074D1 (de) Einen basischen Fibroblastwachstumsfaktor enthaltende Mittel zur Behandlung von Knochenkrankheiten
JPH0551400A (ja) 短鎖コラーゲン
DE68908020D1 (de) Entzuendungshemmendes mittel zur behandlung der krankhaften prostataerweiterung, ein verfahren fuer seine herstellung und dieses enthaltende pharmazeutische zusammensetzungen.
DE69837380D1 (de) Biologisches material zur behandlung eines säugetieres durch transfer einesfür einen antikörper kodierendes gen und eine pharmazeutische zusammensetzungdie diese enthält
MD899G2 (ro) Procedeu de activizare a osteogenezei reparatorii
Africa An Act (No. 65 of 1983) to provide for the donation or the making available of human bodies and tissue for the purposes of medical or dental training, research or therapy or the advancement of medicine or dentistry in general; for the post-mortem examination of certain human bodies; for the removal of tissue, blood and gametes from the bodies of living persons and the use thereof for medical or dental purposes; for the control of the artificial insemination of persons; and for the regulation of the import and export of human tissue, blood and gametes; and to provide for matters connected therewith. Date of commencement: 12 July 1985 (the Human Tissue Act, 1983)

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee