ATE192495T1 - Carboxypeptidase-ähnliches protein aus knochen und verfahren zur dessen herstellung - Google Patents

Carboxypeptidase-ähnliches protein aus knochen und verfahren zur dessen herstellung

Info

Publication number
ATE192495T1
ATE192495T1 AT93113604T AT93113604T ATE192495T1 AT E192495 T1 ATE192495 T1 AT E192495T1 AT 93113604 T AT93113604 T AT 93113604T AT 93113604 T AT93113604 T AT 93113604T AT E192495 T1 ATE192495 T1 AT E192495T1
Authority
AT
Austria
Prior art keywords
bone
protein
carboxypeptidase
osf
production
Prior art date
Application number
AT93113604T
Other languages
English (en)
Inventor
Shinji Kawai
Sunao Takeshita
Makoto Okazaki
Egon Dr Amann
Original Assignee
Hoechst Marion Roussel Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Ltd filed Critical Hoechst Marion Roussel Ltd
Application granted granted Critical
Publication of ATE192495T1 publication Critical patent/ATE192495T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Woven Fabrics (AREA)
AT93113604T 1992-08-28 1993-08-25 Carboxypeptidase-ähnliches protein aus knochen und verfahren zur dessen herstellung ATE192495T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP23002992 1992-08-28
JP32403392A JP3472587B2 (ja) 1992-08-28 1992-12-03 骨関連カルボキシペプチダーゼ様タンパク質およびその製造法

Publications (1)

Publication Number Publication Date
ATE192495T1 true ATE192495T1 (de) 2000-05-15

Family

ID=26529108

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93113604T ATE192495T1 (de) 1992-08-28 1993-08-25 Carboxypeptidase-ähnliches protein aus knochen und verfahren zur dessen herstellung

Country Status (10)

Country Link
US (1) US5460951A (de)
EP (1) EP0588118B1 (de)
JP (1) JP3472587B2 (de)
AT (1) ATE192495T1 (de)
AU (1) AU663217B2 (de)
CA (1) CA2104998A1 (de)
DE (1) DE69328527T2 (de)
DK (1) DK0588118T3 (de)
ES (1) ES2147556T3 (de)
PT (1) PT588118E (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3560252B2 (ja) * 1992-08-28 2004-09-02 アベンティス ファーマ株式会社 骨関連カドヘリン様タンパク質およびその製造法
JPH06121678A (ja) * 1992-08-28 1994-05-06 Hoechst Japan Ltd 骨関連サルファターゼ様タンパク質およびその製造法
JPH06256210A (ja) * 1993-03-10 1994-09-13 Hoechst Japan Ltd 骨関連転写制御因子様タンパク質およびその製造法
IL116696A (en) * 1995-01-25 1999-08-17 Bio Technology General Corp Production of enzymatically active recombinant carboxypeptidase b
US6468766B1 (en) 1996-03-15 2002-10-22 President And Fellows Of Harvard College Aortic carboxypeptidase-like polypeptide
WO1997033900A1 (en) * 1996-03-15 1997-09-18 President And Fellows Of Harvard College E2a-binding protein
EP0965597A4 (de) * 1996-12-27 2003-01-08 Mochida Pharm Co Ltd Zellmembran-wirksame medikamente
US20020137890A1 (en) * 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US6420155B1 (en) * 1999-10-14 2002-07-16 Curagen Corporation Aortic carboxypeptidase-like protein and nucleic acids encoding same
ATE404677T1 (de) * 2000-05-16 2008-08-15 Millennium Pharm Inc Behandlungsverfahren unter verwendung von 17906 und dessen anwendungen
KR20010000464A (ko) * 2000-10-02 2001-01-05 김철주 골다공증 진단용 단백질칩
US20040081653A1 (en) * 2002-08-16 2004-04-29 Raitano Arthur B. Nucleic acids and corresponding proteins entitled 251P5G2 useful in treatment and detection of cancer
WO2005013809A2 (en) 2003-08-08 2005-02-17 Interleukin Genetics, Inc. Diagnostic and therapeutics for osteoporosis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06121678A (ja) * 1992-08-28 1994-05-06 Hoechst Japan Ltd 骨関連サルファターゼ様タンパク質およびその製造法
DE4228839A1 (de) * 1992-08-29 1994-03-03 Behringwerke Ag Verfahren zum Nachweis und zur Bestimmung von Mediatoren

Also Published As

Publication number Publication date
DE69328527T2 (de) 2001-01-11
CA2104998A1 (en) 1994-03-01
EP0588118B1 (de) 2000-05-03
EP0588118A3 (de) 1995-01-11
US5460951A (en) 1995-10-24
DE69328527D1 (de) 2000-06-08
DK0588118T3 (da) 2000-10-02
PT588118E (pt) 2000-09-29
JPH06121682A (ja) 1994-05-06
JP3472587B2 (ja) 2003-12-02
ES2147556T3 (es) 2000-09-16
AU4492393A (en) 1994-03-03
AU663217B2 (en) 1995-09-28
EP0588118A2 (de) 1994-03-23

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee