ATE522520T1 - Neues syntheseverfahren für fluorquinolone - Google Patents
Neues syntheseverfahren für fluorquinoloneInfo
- Publication number
- ATE522520T1 ATE522520T1 AT08104076T AT08104076T ATE522520T1 AT E522520 T1 ATE522520 T1 AT E522520T1 AT 08104076 T AT08104076 T AT 08104076T AT 08104076 T AT08104076 T AT 08104076T AT E522520 T1 ATE522520 T1 AT E522520T1
- Authority
- AT
- Austria
- Prior art keywords
- alkyl
- compound
- nrr1a
- optionally substituted
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0755240A FR2916446B1 (fr) | 2007-05-24 | 2007-05-24 | Nouveau procede de synthese de fluoroquinolones |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE522520T1 true ATE522520T1 (de) | 2011-09-15 |
Family
ID=38935887
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08104076T ATE522520T1 (de) | 2007-05-24 | 2008-05-23 | Neues syntheseverfahren für fluorquinolone |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8093381B2 (de) |
| EP (1) | EP2138490B1 (de) |
| JP (1) | JP5373320B2 (de) |
| CN (1) | CN101337934A (de) |
| AT (1) | ATE522520T1 (de) |
| ES (1) | ES2372885T3 (de) |
| FR (1) | FR2916446B1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101759629B (zh) * | 2009-12-22 | 2012-01-11 | 北大方正集团有限公司 | 西他沙星中间体的制备方法 |
| CN101768167B (zh) * | 2010-01-15 | 2012-07-04 | 浙江东亚药业有限公司 | 左氧氟沙星的缩哌合成方法 |
| CN101792443A (zh) * | 2010-03-09 | 2010-08-04 | 北京欧凯纳斯科技有限公司 | 氟代喹诺酮衍生物及其制备方法和用途 |
| CN102827143A (zh) * | 2012-08-14 | 2012-12-19 | 安徽赛诺医药化工有限公司 | 一种合成氟喹诺酮及其盐的新方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS53141286A (en) | 1977-05-16 | 1978-12-08 | Kyorin Seiyaku Kk | Novel substituted quinolinecarboxylic acid |
| SE440354B (sv) | 1981-02-19 | 1985-07-29 | Kyorin Seiyaku Kk | Kinolinkarboxylsyraderivat |
| GB2095171A (en) * | 1981-02-27 | 1982-09-29 | Ushio Electric Inc | Apparatus for heat-laminating a sheet |
| US4665079A (en) | 1984-02-17 | 1987-05-12 | Warner-Lambert Company | Antibacterial agents |
| US4473568A (en) | 1983-03-01 | 1984-09-25 | Warner Lambert Company | Antibacterial thiazolidine or thiomorpholine substituted quinolines |
| AU553415B2 (en) * | 1983-09-19 | 1986-07-17 | Abbott Japan Co., Ltd. | 6-fluoro-1-4-dihydro-4-oxo-7-substituted piperazinyl- quinoline-3-carboxylic acids |
| EP0230053A3 (de) | 1986-01-17 | 1988-03-30 | American Cyanamid Company | 7-(Substituierte)Piperazinyl-1-äthyl-6-fluor-1,4-dihydro-4-oxo-3-chinolinkarbonsäure |
| JP2693988B2 (ja) | 1987-06-24 | 1997-12-24 | キノイン ギオギスゼル エス ベギエスゼチ テルメケク ギヤラ アールティー． | キノリンカルボン酸誘導体の製造方法 |
| IL88003A (en) * | 1987-10-16 | 1992-11-15 | Dainippon Pharmaceutical Co | Quinoline derivatives,their preparation and pharmaceutical compositions containing them |
| JPH0794452B2 (ja) * | 1987-10-16 | 1995-10-11 | 大日本製薬株式会社 | 新規ピリドンカルボン酸誘導体、そのエステルおよびその塩 |
| JPH02231424A (ja) * | 1988-10-17 | 1990-09-13 | Dainippon Pharmaceut Co Ltd | 抗菌剤 |
| DE3918544A1 (de) * | 1989-06-07 | 1990-12-13 | Bayer Ag | Verfahren zur herstellung von 7-(3-amino- sowie 3-amino-methyl-1-pyrrolidinyl)-3-chinolon- carbonsaeuren sowie -naphthyridoncarbonsaeuren |
| DE4342186A1 (de) * | 1993-12-10 | 1995-06-14 | Bayer Ag | Eintopfverfahren zur Herstellung von 3-Chinoloncarbonsäurederivaten |
| GB2291421A (en) * | 1994-07-16 | 1996-01-24 | Pfizer | A process for preparing a quinoline carboxylic acid |
| WO2003010144A2 (en) * | 2001-07-25 | 2003-02-06 | Farmaceutsko-Hemijska Industrija 'zdravlje' | A process for synthesis of fluoroquinolonic derivatives |
-
2007
- 2007-05-24 FR FR0755240A patent/FR2916446B1/fr active Active
-
2008
- 2008-05-22 US US12/125,434 patent/US8093381B2/en active Active
- 2008-05-23 CN CNA200810098225XA patent/CN101337934A/zh active Pending
- 2008-05-23 EP EP08104076A patent/EP2138490B1/de active Active
- 2008-05-23 JP JP2008135975A patent/JP5373320B2/ja active Active
- 2008-05-23 ES ES08104076T patent/ES2372885T3/es active Active
- 2008-05-23 AT AT08104076T patent/ATE522520T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP2138490B1 (de) | 2011-08-31 |
| US8093381B2 (en) | 2012-01-10 |
| ES2372885T3 (es) | 2012-01-27 |
| FR2916446B1 (fr) | 2009-08-21 |
| JP5373320B2 (ja) | 2013-12-18 |
| FR2916446A1 (fr) | 2008-11-28 |
| EP2138490A1 (de) | 2009-12-30 |
| CN101337934A (zh) | 2009-01-07 |
| JP2009001560A (ja) | 2009-01-08 |
| US20090054643A1 (en) | 2009-02-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |