ATE522214T1 - Therapeutisches mittel für nahrungskompetenzstörungen im magen - Google Patents
Therapeutisches mittel für nahrungskompetenzstörungen im magenInfo
- Publication number
- ATE522214T1 ATE522214T1 AT03745958T AT03745958T ATE522214T1 AT E522214 T1 ATE522214 T1 AT E522214T1 AT 03745958 T AT03745958 T AT 03745958T AT 03745958 T AT03745958 T AT 03745958T AT E522214 T1 ATE522214 T1 AT E522214T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- therapeutic agent
- competency
- nutritional
- stomach
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 2
- 229940124597 therapeutic agent Drugs 0.000 title abstract 2
- 235000016709 nutrition Nutrition 0.000 title 1
- 210000002784 stomach Anatomy 0.000 title 1
- 230000004308 accommodation Effects 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000002541 furyl group Chemical group 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000001771 impaired effect Effects 0.000 abstract 1
- 125000002971 oxazolyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000335 thiazolyl group Chemical group 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002104894 | 2002-04-08 | ||
| PCT/JP2003/004445 WO2003084537A1 (en) | 2002-04-08 | 2003-04-08 | Therapeutic agent for food competence disorder in stomach |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE522214T1 true ATE522214T1 (de) | 2011-09-15 |
Family
ID=28786350
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03745958T ATE522214T1 (de) | 2002-04-08 | 2003-04-08 | Therapeutisches mittel für nahrungskompetenzstörungen im magen |
Country Status (14)
| Country | Link |
|---|---|
| US (4) | US20050176788A1 (enExample) |
| EP (2) | EP2301540A1 (enExample) |
| JP (2) | JP5281226B2 (enExample) |
| KR (4) | KR20110010837A (enExample) |
| CN (2) | CN1646123A (enExample) |
| AT (1) | ATE522214T1 (enExample) |
| AU (1) | AU2003236326B2 (enExample) |
| CA (1) | CA2481916C (enExample) |
| CY (1) | CY1112057T1 (enExample) |
| DK (1) | DK1493441T3 (enExample) |
| ES (1) | ES2368732T3 (enExample) |
| PT (1) | PT1493441E (enExample) |
| SI (1) | SI1493441T1 (enExample) |
| WO (1) | WO2003084537A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104447612A (zh) * | 2013-09-16 | 2015-03-25 | 天津市汉康医药生物技术有限公司 | 阿考替胺水合物晶型及其制备方法和用途 |
| CN103980226A (zh) * | 2014-05-10 | 2014-08-13 | 杭州新博思生物医药有限公司 | 盐酸阿考替胺水合物晶型及其制备方法 |
| CN105315225A (zh) * | 2014-07-07 | 2016-02-10 | 中美华世通生物医药科技（武汉）有限公司 | 阿考替胺的酸加成盐及其制备方法 |
| CN104045606B (zh) * | 2014-07-11 | 2015-09-30 | 杭州新博思生物医药有限公司 | 一锅法制备阿考替胺盐酸盐的方法 |
| CN109988121B (zh) * | 2019-04-28 | 2023-01-03 | 梯尔希（南京）药物研发有限公司 | 一种阿考替胺衍生物的制备方法 |
| MX2024000751A (es) | 2021-07-14 | 2024-03-25 | Blueprint Medicines Corp | Compuestos heterociclicos como inhibidores de map4k1. |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1063442C (zh) * | 1995-05-18 | 2001-03-21 | 泽里新药工业株式会社 | 氨基噻唑衍生物、含有它们的药物组合物及其用途 |
| JPH10212271A (ja) | 1997-01-31 | 1998-08-11 | Zeria Pharmaceut Co Ltd | Ｎ−置換ベンゾイルアミン誘導体、それを含有する医薬及び該化合物の製造中間体 |
| DK0994108T3 (da) * | 1997-06-24 | 2003-08-18 | Zeria Pharm Co Ltd | Fremgangsmåde til fremstilling af 2-hydroxybenzamidderivater |
| US5981556A (en) * | 1997-07-22 | 1999-11-09 | G.D. Searle & Co. | 1,3-diazolino and 1,3-diazolidino heterocycles as useful nitric oxide synthase inhibitors |
| CA2352278A1 (en) * | 1998-11-23 | 2000-06-02 | Janssen Pharmaceutica, N.V. | Use of prucalopride for the manufacture of a medicament for the treatment of dyspepsia |
| UA73122C2 (en) * | 1999-06-02 | 2005-06-15 | Janssen Pharmaceutica Nv | Derivatives of benzodioxane, benzofuran or benzopyran substituted by aminoalkyl |
| AU782648B2 (en) * | 1999-11-23 | 2005-08-18 | Janssen Pharmaceutica N.V. | Use of 5HT3 agonists for relaxing the fundus |
| GB0002336D0 (en) * | 2000-02-01 | 2000-03-22 | Glaxo Group Ltd | Medicaments |
| JP4876367B2 (ja) * | 2000-09-08 | 2012-02-15 | ゼリア新薬工業株式会社 | アミノチアゾール誘導体を有効成分とする大腸運動不全治療剤 |
| US6986882B2 (en) * | 2002-01-17 | 2006-01-17 | Astrazeneca Ab | Therapy for functional dyspepsia |
-
2003
- 2003-04-08 EP EP10010621A patent/EP2301540A1/en not_active Withdrawn
- 2003-04-08 KR KR1020117000220A patent/KR20110010837A/ko not_active Ceased
- 2003-04-08 AU AU2003236326A patent/AU2003236326B2/en not_active Expired
- 2003-04-08 CN CNA038079755A patent/CN1646123A/zh active Pending
- 2003-04-08 ES ES03745958T patent/ES2368732T3/es not_active Expired - Lifetime
- 2003-04-08 AT AT03745958T patent/ATE522214T1/de active
- 2003-04-08 DK DK03745958.3T patent/DK1493441T3/da active
- 2003-04-08 WO PCT/JP2003/004445 patent/WO2003084537A1/ja not_active Ceased
- 2003-04-08 PT PT03745958T patent/PT1493441E/pt unknown
- 2003-04-08 CN CN201010611741.5A patent/CN102125551B/zh not_active Expired - Lifetime
- 2003-04-08 CA CA2481916A patent/CA2481916C/en not_active Expired - Lifetime
- 2003-04-08 US US10/509,335 patent/US20050176788A1/en not_active Abandoned
- 2003-04-08 SI SI200332073T patent/SI1493441T1/sl unknown
- 2003-04-08 KR KR10-2004-7015764A patent/KR20050002925A/ko not_active Ceased
- 2003-04-08 KR KR1020127005319A patent/KR20120037035A/ko not_active Ceased
- 2003-04-08 EP EP03745958A patent/EP1493441B1/en not_active Expired - Lifetime
- 2003-04-08 KR KR1020137022604A patent/KR101423284B1/ko not_active Expired - Lifetime
- 2003-04-08 JP JP2003581777A patent/JP5281226B2/ja not_active Expired - Lifetime
-
2009
- 2009-02-17 US US12/372,234 patent/US20090156652A1/en not_active Abandoned
-
2011
- 2011-01-05 JP JP2011000499A patent/JP5360075B2/ja not_active Expired - Lifetime
- 2011-11-16 CY CY20111101103T patent/CY1112057T1/el unknown
-
2014
- 2014-12-22 US US14/579,102 patent/US20150141475A1/en not_active Abandoned
-
2020
- 2020-08-20 US US16/998,637 patent/US20200375954A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR101423284B1 (ko) | 2014-07-24 |
| CN1646123A (zh) | 2005-07-27 |
| US20200375954A1 (en) | 2020-12-03 |
| JPWO2003084537A1 (ja) | 2005-08-11 |
| AU2003236326A1 (en) | 2003-10-20 |
| EP1493441A1 (en) | 2005-01-05 |
| EP1493441A4 (en) | 2007-10-17 |
| US20090156652A1 (en) | 2009-06-18 |
| KR20110010837A (ko) | 2011-02-07 |
| JP5360075B2 (ja) | 2013-12-04 |
| CA2481916A1 (en) | 2003-10-16 |
| DK1493441T3 (da) | 2011-10-17 |
| US20050176788A1 (en) | 2005-08-11 |
| US20150141475A1 (en) | 2015-05-21 |
| JP5281226B2 (ja) | 2013-09-04 |
| CA2481916C (en) | 2013-02-26 |
| JP2011068692A (ja) | 2011-04-07 |
| SI1493441T1 (sl) | 2011-12-30 |
| KR20130101162A (ko) | 2013-09-12 |
| CY1112057T1 (el) | 2015-11-04 |
| PT1493441E (pt) | 2011-09-28 |
| ES2368732T3 (es) | 2011-11-21 |
| AU2003236326B2 (en) | 2008-02-28 |
| KR20050002925A (ko) | 2005-01-10 |
| WO2003084537A1 (en) | 2003-10-16 |
| CN102125551A (zh) | 2011-07-20 |
| KR20120037035A (ko) | 2012-04-18 |
| EP2301540A1 (en) | 2011-03-30 |
| EP1493441B1 (en) | 2011-08-31 |
| CN102125551B (zh) | 2015-07-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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