ATE520026T1 - Sequenzielle analyse biologischer proben - Google Patents

Sequenzielle analyse biologischer proben

Info

Publication number
ATE520026T1
ATE520026T1 AT07871481T AT07871481T ATE520026T1 AT E520026 T1 ATE520026 T1 AT E520026T1 AT 07871481 T AT07871481 T AT 07871481T AT 07871481 T AT07871481 T AT 07871481T AT E520026 T1 ATE520026 T1 AT E520026T1
Authority
AT
Austria
Prior art keywords
sample
fluorescent probe
binding
detecting
probe
Prior art date
Application number
AT07871481T
Other languages
German (de)
English (en)
Inventor
Zhengyu Pang
Robert John Filkins
Michael Christopher Montalto
Fiona Ginty
Michael J Gerdes
Ali Can
Maureen Ann Bresnahan
Anup Sood
Original Assignee
Gen Electric
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/560,599 external-priority patent/US7629125B2/en
Application filed by Gen Electric filed Critical Gen Electric
Application granted granted Critical
Publication of ATE520026T1 publication Critical patent/ATE520026T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
AT07871481T 2006-11-16 2007-11-15 Sequenzielle analyse biologischer proben ATE520026T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/560,599 US7629125B2 (en) 2006-11-16 2006-11-16 Sequential analysis of biological samples
US11/864,085 US7741045B2 (en) 2006-11-16 2007-09-28 Sequential analysis of biological samples
PCT/US2007/084800 WO2008064067A2 (en) 2006-11-16 2007-11-15 Method for the sequential analysis of different components in a single biological sample and reagents therefor

Publications (1)

Publication Number Publication Date
ATE520026T1 true ATE520026T1 (de) 2011-08-15

Family

ID=39313177

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07871481T ATE520026T1 (de) 2006-11-16 2007-11-15 Sequenzielle analyse biologischer proben

Country Status (11)

Country Link
US (1) US7741045B2 (https=)
EP (2) EP2381257B1 (https=)
JP (1) JP5149303B2 (https=)
AT (1) ATE520026T1 (https=)
AU (1) AU2007323794B2 (https=)
CA (1) CA2669092C (https=)
DK (1) DK2082226T3 (https=)
ES (1) ES2459725T3 (https=)
PL (1) PL2082226T3 (https=)
PT (1) PT2082226E (https=)
WO (1) WO2008064067A2 (https=)

Families Citing this family (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8060348B2 (en) * 2006-08-07 2011-11-15 General Electric Company Systems for analyzing tissue samples
US8131476B2 (en) * 2006-08-07 2012-03-06 General Electric Company System and method for co-registering multi-channel images of a tissue micro array
US20080032321A1 (en) * 2006-08-07 2008-02-07 General Electric Company System and methods for analyzing images of tissue samples
US7629125B2 (en) * 2006-11-16 2009-12-08 General Electric Company Sequential analysis of biological samples
US20100279272A1 (en) * 2008-02-13 2010-11-04 Michael Craig Burrell Multiplexed analysis methods using sers-active nanoparticles
EP2110076A1 (en) * 2008-02-19 2009-10-21 Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Method and device for near-field dual-wave modality imaging
CA2731409C (en) 2008-07-25 2016-01-05 Daniel Razansky Quantitative multi-spectral opto-acoustic tomography (msot) of tissue biomarkers
JP5566456B2 (ja) 2009-06-29 2014-08-06 ヘルムホルツ・ツェントルム・ミュンヒェン・ドイチェス・フォルシュンクスツェントルム・フューア・ゲズントハイト・ウント・ウムベルト(ゲーエムベーハー) 被写体を熱音響撮像するための撮像装置及び撮像方法、コンピュータプログラム並びにコンピュータで読み取り可能な記憶媒体を備える装置
US10292593B2 (en) 2009-07-27 2019-05-21 Helmholtz Zentrum München Deutsches Forschungszentrum Für Gesundheit Und Umwelt (Gmbh) Imaging device and method for optoacoustic imaging of small animals
US8269827B2 (en) * 2009-09-29 2012-09-18 General Electric Company System and methods for mapping fluorescent images into a bright field color space
US9677125B2 (en) * 2009-10-21 2017-06-13 General Electric Company Detection of plurality of targets in biological samples
WO2012058638A2 (en) 2010-10-29 2012-05-03 President And Fellows Of Harvard College Nucleic acid nanostructure barcode probes
US20120269418A1 (en) * 2011-04-22 2012-10-25 Ge Global Research Analyzing the expression of biomarkers in cells with clusters
US8639013B2 (en) 2011-08-17 2014-01-28 General Electric Company System and methods for generating a brightfield image using fluorescent images
US9176032B2 (en) 2011-12-23 2015-11-03 General Electric Company Methods of analyzing an H and E stained biological sample
US8568991B2 (en) 2011-12-23 2013-10-29 General Electric Company Photoactivated chemical bleaching of dyes
WO2013137715A1 (en) * 2012-03-16 2013-09-19 Umc Utrecht Holding B.V. Biomarkers for adverse cardiac remodeling
ES2678211T3 (es) 2012-03-27 2018-08-09 Ventana Medical Systems, Inc. Conjugados de señalización y procedimientos de uso
US11573235B2 (en) 2012-03-30 2023-02-07 Leica Microsystems Cms Gmbh Methods for generating an image of a biological sample
US20140024024A1 (en) * 2012-07-17 2014-01-23 General Electric Company Methods of detecting dna, rna and protein in biological samples
EP2742854B1 (en) 2012-12-11 2021-03-10 iThera Medical GmbH Handheld device and method for tomographic optoacoustic imaging of an object
EP2754388B1 (en) 2013-01-15 2020-09-09 Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt GmbH System and method for quality-enhanced high-rate optoacoustic imaging of an object
JP2016513794A (ja) 2013-03-06 2016-05-16 ゼネラル・エレクトリック・カンパニイ H&e染色された生体試料を分析する方法
HK1213296A1 (zh) * 2013-06-04 2016-06-30 豪夫迈‧罗氏有限公司 用於fret的新化合物及与其相关的方法
CA2919833A1 (en) 2013-07-30 2015-02-05 President And Fellows Of Harvard College Quantitative dna-based imaging and super-resolution imaging
US9778263B2 (en) 2013-11-13 2017-10-03 General Electric Company Quantitative in situ characterization of biological samples
US11982673B2 (en) 2014-03-05 2024-05-14 Autolus Limited Methods
DK3241561T3 (da) * 2014-03-05 2025-06-30 Autolus Ltd Konjugeret antistof eller bispecifik t-celle-engager, som selektivt binder enten tcr-beta konstant region 1 (trbc1) eller trbc2
US10294510B2 (en) 2014-03-11 2019-05-21 President And Fellows Of Harvard College High-throughput and highly multiplexed imaging with programmable nucleic acid probes
EP4328322A3 (en) 2014-07-30 2024-05-22 President and Fellows of Harvard College Probe library construction
US9933431B2 (en) 2014-08-22 2018-04-03 Arizona Board Of Regents On Behalf Of Arizona State University System and method for iterative detection of biological molecules
EP3037820A1 (en) 2014-12-27 2016-06-29 Miltenyi Biotec GmbH Cell detection methods and reagents having a releasable labelling moiety
JP6841609B2 (ja) 2015-07-10 2021-03-10 3スキャン インコーポレイテッド 組織学的染色の空間的多重化
SG10202107053QA (en) 2015-07-17 2021-08-30 Nanostring Technologies Inc Simultaneous quantification of gene expression in a user-defined region of a cross-sectioned tissue
WO2017015097A1 (en) 2015-07-17 2017-01-26 Nanostring Technologies, Inc. Simultaneous quantification of a plurality of proteins in a user-defined region of a cross-sectioned tissue
US20170241911A1 (en) 2016-02-22 2017-08-24 Miltenyi Biotec Gmbh Automated analysis tool for biological specimens
US10871490B2 (en) 2016-02-29 2020-12-22 Multenyi Biotec, gmbH Assay for detection of chimeric antigen receptor T cells
WO2017202962A1 (en) 2016-05-24 2017-11-30 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for the treatment of non small cell lung cancer (nsclc) that coexists with chronic obstructive pulmonary disease (copd)
EP3478409A1 (en) 2016-06-29 2019-05-08 Miltenyi Biotec GmbH Multilevel disposable cartridge for biological specimens
CN106290878A (zh) * 2016-09-10 2017-01-04 天津大学 基于量子点的胰腺癌肿瘤标志物ca242免疫层析试纸条的制备方法
CN118345145A (zh) 2016-12-09 2024-07-16 乌尔蒂维尤股份有限公司 用于使用标记的核酸成像剂进行多路复用成像的改进方法
WO2018122245A1 (en) 2016-12-28 2018-07-05 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods of predicting the survival time of patients suffering from cms3 colorectal cancer
WO2018122249A1 (en) 2016-12-28 2018-07-05 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for predicting the survival time of patients suffering from a microsatellite stable colorectal cancer
WO2018202850A1 (en) 2017-05-05 2018-11-08 INSERM (Institut National de la Santé et de la Recherche Médicale) Microtubule-targeting drugs as immune checkpoint inhibitors and methods of screening novel immune checkpoint inhibitors for the treatment of cancers and infectious diseases
US11788123B2 (en) 2017-05-26 2023-10-17 President And Fellows Of Harvard College Systems and methods for high-throughput image-based screening
EP3489684B1 (en) * 2017-11-27 2024-06-26 Miltenyi Biotec B.V. & Co. KG Method for photobleaching stained cells
US20190249248A1 (en) 2018-02-12 2019-08-15 Nanostring Technologies, Inc. Biomolecular probes and methods of detecting gene and protein expression
JP2020071152A (ja) * 2018-10-31 2020-05-07 ソニー株式会社 免疫染色方法、免疫染色システム、および免疫染色キット
EP3894583A4 (en) 2018-12-13 2022-11-09 President and Fellows of Harvard College AMPLIFICATION METHODS AND SYSTEMS FOR MERFISH AND OTHER APPLICATIONS
CN113574386A (zh) 2019-01-03 2021-10-29 国家医疗保健研究所 用于增强癌症患者的cd8+t细胞依赖性免疫应答的方法和药物组合物
CN109770853B (zh) * 2019-01-30 2022-01-14 上海师范大学 一种斑马鱼伤口检测方法
US11633741B2 (en) 2019-03-19 2023-04-25 Miltenyi Biotec B.V. & Co. KG Slide chamber
EP3947737A2 (en) 2019-04-02 2022-02-09 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods of predicting and preventing cancer in patients having premalignant lesions
US20220160692A1 (en) 2019-04-09 2022-05-26 INSERM (Institut National de la Santé et de la Recherche Médicale) Use of sk2 inhibitors in combination with immune checkpoint blockade therapy for the treatment of cancer
CN113677995A (zh) 2019-04-23 2021-11-19 美天施生物科技有限两合公司 使用具有用于增加荧光亮度的接头和酶促可释放荧光部分的缀合物的可逆细胞检测
SG11202112712RA (en) 2019-06-03 2021-12-30 Inst Nat Sante Rech Med Methods for modulating a treatment regimen
EP4045898A4 (en) 2019-10-17 2024-01-10 C2Sense, Inc. LUMINESCENCE IMAGING FOR CAPTURE
CN114729890A (zh) * 2019-10-17 2022-07-08 C2感官有限公司 用于感测和/或认证的发光成像
WO2021074391A1 (en) 2019-10-17 2021-04-22 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for diagnosing nasal intestinal type adenocarcinomas
WO2021170777A1 (en) 2020-02-28 2021-09-02 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for diagnosing, prognosing and managing treatment of breast cancer
EP3916393B1 (en) 2020-05-27 2023-01-25 Miltenyi Biotec B.V. & Co. KG Method for detection of cells by repetitive staining and destaining
EP3916388A1 (en) 2020-05-27 2021-12-01 Miltenyi Biotec B.V. & Co. KG Reagents for detection of chimeric antigen receptor cells
EP4172628A1 (en) 2020-06-30 2023-05-03 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for predicting the risk of recurrence and/or death of patients suffering from a solid cancer after preoperative adjuvant therapy and radical surgery
US20230235408A1 (en) 2020-06-30 2023-07-27 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for predicting the risk of recurrence and/or death of patients suffering from a solid cancer after preoperative adjuvant therapies
WO2022200303A1 (en) 2021-03-23 2022-09-29 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for the diagnosis and treatment of t cell-lymphomas
EP4320442A1 (en) 2021-04-09 2024-02-14 Neogenomics Laboratories, Inc. Perivascular accumulation of immune cells in the diagnosis and treatment of cancer
CN113684256B (zh) * 2021-08-30 2024-05-14 中国药科大学 基于绿色溶剂及可编程寡核苷酸探针的多重定位检测多种靶标的方法
WO2023143179A1 (zh) * 2022-01-28 2023-08-03 南京大学 一种对抗原样本的处理方法和应用
WO2023144303A1 (en) 2022-01-31 2023-08-03 INSERM (Institut National de la Santé et de la Recherche Médicale) Cd38 as a biomarker and biotarget in t-cell lymphomas
US20250035635A1 (en) 2022-03-17 2025-01-30 Institut National De La Sante Et De La Recherche Medicale Methods for predicting response to an immunotherapeutic treatment in a patient with a cancer
WO2023198648A1 (en) 2022-04-11 2023-10-19 Institut National de la Santé et de la Recherche Médicale Methods for the diagnosis and treatment of t-cell malignancies
WO2023198874A1 (en) 2022-04-15 2023-10-19 Institut National de la Santé et de la Recherche Médicale Methods for the diagnosis and treatment of t cell-lymphomas
WO2024003310A1 (en) 2022-06-30 2024-01-04 Institut National de la Santé et de la Recherche Médicale Methods for the diagnosis and treatment of acute lymphoblastic leukemia
JP2025526336A (ja) 2022-07-22 2025-08-13 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル T細胞悪性腫瘍におけるバイオマーカー及びバイオターゲットとしてのgarp
WO2024023283A1 (en) 2022-07-29 2024-02-01 Institut National de la Santé et de la Recherche Médicale Lrrc33 as a biomarker and biotarget in cutaneous t-cell lymphomas
JP2025536268A (ja) 2022-10-12 2025-11-05 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル T細胞悪性腫瘍におけるバイオマーカー及びバイオターゲットとしてのcd81
WO2025068451A1 (en) 2023-09-28 2025-04-03 Miltenyi Biotec B.V. & Co. KG Flow cell for sequencing

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3130513B2 (ja) * 1989-04-19 2001-01-31 イビデン株式会社 生体活性物質測定用装置
US5807522A (en) * 1994-06-17 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods for fabricating microarrays of biological samples
DE4421891C2 (de) 1994-06-23 1996-05-15 Helmut Prof Dr Med Feucht Verfahren zum Nachweis von komplementaktivierenden IgG-Antikörpern gegen HLA-DR-Antigene
US5830645A (en) * 1994-12-09 1998-11-03 The Regents Of The University Of California Comparative fluorescence hybridization to nucleic acid arrays
DE19709348C2 (de) * 1996-05-29 1999-07-01 Schubert Walter Dr Md Automatisches Multi-Epitop-Ligand-Kartierungsverfahren
DE19717904A1 (de) * 1997-04-23 1998-10-29 Diagnostikforschung Inst Säurelabile und enzymatisch spaltbare Farbstoffkonstrukte zur Diagnostik mit Nahinfrarotlicht und zur Therapie
US6083486A (en) * 1998-05-14 2000-07-04 The General Hospital Corporation Intramolecularly-quenched near infrared fluorescent probes
WO2000003034A2 (en) 1998-07-10 2000-01-20 Chromagen, Inc. Novel polycyclic aromatic fluorogenic substrates for hydrolases
US6573043B1 (en) 1998-10-07 2003-06-03 Genentech, Inc. Tissue analysis and kits therefor
WO2000058507A1 (en) 1999-03-30 2000-10-05 Solexa Ltd. Polynucleotide sequencing
AU7537200A (en) * 1999-09-29 2001-04-30 Solexa Ltd. Polynucleotide sequencing
GB0002389D0 (en) * 2000-02-02 2000-03-22 Solexa Ltd Molecular arrays
DE10014685B4 (de) * 2000-03-24 2004-07-01 Schubert, Walter, Dr. Verfahren zur Identifizierung von zellspezifischen Zielstrukturen
WO2001086296A2 (en) * 2000-05-05 2001-11-15 Agilix Corporation Highly multiplexed reporter carrier systems
US20030044353A1 (en) * 2001-01-05 2003-03-06 Ralph Weissleder Activatable imaging probes
WO2002079771A1 (en) 2001-03-30 2002-10-10 The Samuel Roberts Noble Foundation, Inc. Silver destaining method
US7219016B2 (en) * 2001-04-20 2007-05-15 Yale University Systems and methods for automated analysis of cells and tissues
US20020173053A1 (en) * 2001-04-27 2002-11-21 Bassam Damaj Multiple simultaneous antigen detection by immunohistochemistry
US20040241688A1 (en) * 2001-07-19 2004-12-02 Cuneyt Bukusoglu Human tissue specific drug screening procedure
US8323903B2 (en) * 2001-10-12 2012-12-04 Life Technologies Corporation Antibody complexes and methods for immunolabeling
WO2003061711A2 (en) * 2002-01-16 2003-07-31 Visen Medical, Inc. Chromophore probes for optical imaging
EP1573061A4 (en) * 2002-12-18 2006-03-08 Aclara Biosciences Inc MULTIPLEX IMMUNOHISTOCHEMICAL TESTS USING MOLECULAR MARKERS
WO2005017485A2 (en) 2003-05-22 2005-02-24 Agdia, Inc. Multiplex enzyme-linked immunosorbent assay for detecting multiple analytes
US20050287578A1 (en) * 2004-06-28 2005-12-29 Exagen Diagnostics, Inc. Methods for RNA fluorescence in situ hybridization
JP2007033159A (ja) * 2005-07-25 2007-02-08 Assay Corp 蛍光分子で標識された測定対象物質
WO2007055302A1 (ja) * 2005-11-10 2007-05-18 National University Corporation University Of Toyama 生体物質と生体物質結合性物質との結合性評価方法
US8305579B2 (en) * 2006-11-16 2012-11-06 Thomas Pirrie Treynor Sequential analysis of biological samples

Also Published As

Publication number Publication date
PT2082226E (pt) 2011-10-31
EP2082226B1 (en) 2011-08-10
WO2008064067A2 (en) 2008-05-29
WO2008064067A3 (en) 2008-07-10
EP2082226A2 (en) 2009-07-29
DK2082226T3 (da) 2011-11-14
JP5149303B2 (ja) 2013-02-20
EP2381257B1 (en) 2014-03-26
EP2381257A1 (en) 2011-10-26
US7741045B2 (en) 2010-06-22
US20080118934A1 (en) 2008-05-22
AU2007323794B2 (en) 2013-08-22
PL2082226T3 (pl) 2012-01-31
CA2669092C (en) 2016-07-26
JP2010510493A (ja) 2010-04-02
CA2669092A1 (en) 2008-05-29
AU2007323794A1 (en) 2008-05-29
ES2459725T3 (es) 2014-05-12

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