ATE511844T1 - Analgetische und entzündungshemmende zusammensetzungen enthaltend celecoxib und ibuprofen - Google Patents

Analgetische und entzündungshemmende zusammensetzungen enthaltend celecoxib und ibuprofen

Info

Publication number
ATE511844T1
ATE511844T1 AT01946309T AT01946309T ATE511844T1 AT E511844 T1 ATE511844 T1 AT E511844T1 AT 01946309 T AT01946309 T AT 01946309T AT 01946309 T AT01946309 T AT 01946309T AT E511844 T1 ATE511844 T1 AT E511844T1
Authority
AT
Austria
Prior art keywords
analgesic
ibuprofen
compositions containing
inflammatory compositions
containing celecoxib
Prior art date
Application number
AT01946309T
Other languages
English (en)
Inventor
Stephen Cooper
Original Assignee
Wyeth Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Llc filed Critical Wyeth Llc
Application granted granted Critical
Publication of ATE511844T1 publication Critical patent/ATE511844T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT01946309T 2000-06-13 2001-06-13 Analgetische und entzündungshemmende zusammensetzungen enthaltend celecoxib und ibuprofen ATE511844T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21130700P 2000-06-13 2000-06-13
PCT/US2001/018990 WO2001095898A1 (en) 2000-06-13 2001-06-13 Analgesic and anti-inflammatory compositions containing cox-2 inhibitors

Publications (1)

Publication Number Publication Date
ATE511844T1 true ATE511844T1 (de) 2011-06-15

Family

ID=22786362

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01946309T ATE511844T1 (de) 2000-06-13 2001-06-13 Analgetische und entzündungshemmende zusammensetzungen enthaltend celecoxib und ibuprofen

Country Status (22)

Country Link
US (2) US6924303B2 (de)
EP (1) EP1296665B1 (de)
JP (1) JP5579958B2 (de)
KR (1) KR20030019422A (de)
CN (1) CN100588395C (de)
AT (1) ATE511844T1 (de)
AU (2) AU6837701A (de)
BR (1) BR0111767A (de)
CA (1) CA2411960C (de)
DK (1) DK1296665T3 (de)
EA (2) EA200802070A1 (de)
ES (1) ES2365387T3 (de)
HU (1) HU229440B1 (de)
IL (2) IL153303A0 (de)
MX (1) MXPA02012344A (de)
NO (1) NO331092B1 (de)
NZ (1) NZ522957A (de)
PL (1) PL206268B1 (de)
PT (1) PT1296665E (de)
RU (1) RU2003100874A (de)
WO (1) WO2001095898A1 (de)
ZA (1) ZA200209944B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE511844T1 (de) 2000-06-13 2011-06-15 Wyeth Llc Analgetische und entzündungshemmende zusammensetzungen enthaltend celecoxib und ibuprofen
IL163637A0 (en) * 2002-02-19 2005-12-18 Adcock Ingram Ltd Pharmaceutical combinations of cox-2 inhibitors and opiates
US20040161481A1 (en) * 2002-12-18 2004-08-19 Algorx Administration of capsaicinoids
TW200600086A (en) * 2004-06-05 2006-01-01 Astrazeneca Ab Chemical compound
FR2881049B1 (fr) * 2005-01-24 2008-12-26 Vetoquinol Sa Sa Medicament destine a etre administre par voie orale comprenant un inhibiteur de la cyclo-oxygenase-2, et son procede de preparation
US20060281775A1 (en) 2005-06-14 2006-12-14 Applied Pharmacy Services, Inc. Two-component pharmaceutical composition for the treatment of pain
AU2007309281B2 (en) 2006-10-20 2013-10-31 Johnson & Johnson Consumer Inc. Acetaminophen / ibuprofen combinations
TR200904862A1 (tr) * 2009-05-29 2010-12-21 Sanovel İlaç San. Ve Ti̇c. A.Ş. Sukraloz formülasyonu ve üretim prosesi
CA3025734A1 (en) * 2016-05-27 2017-12-07 Dr. Reddy's Laboratories Ltd. Oral composition of celecoxib for treatment of pain

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5331000A (en) * 1992-03-09 1994-07-19 Sepracor Inc. Antipyretic and analgesic methods and compositions containing optically pure R(-) ketoprofen
US5474995A (en) * 1993-06-24 1995-12-12 Merck Frosst Canada, Inc. Phenyl heterocycles as cox-2 inhibitors
RU2139281C1 (ru) * 1993-11-30 1999-10-10 Джи Ди Сирл энд Компани Пиразолилзамещенный бензолсульфонамид или его фармацевтически приемлемая соль, фармацевтическая композиция, способ лечения от воспаления или связанного с воспалением заболевания
CZ291463B6 (cs) 1996-05-17 2003-03-12 Merck And Co., Inc. Farmaceutický prostředek
DE69724788T2 (de) 1996-07-18 2004-08-05 Merck Frosst Canada & Co., Halifax Substituierte pyridine als selektive cyclooxygenase inhibitoren
US6160020A (en) * 1996-12-20 2000-12-12 Mcneill-Ppc, Inc. Alkali metal and alkaline-earth metal salts of acetaminophen
RU2182016C2 (ru) * 1997-03-20 2002-05-10 Панацея Биотек Лтд. Спазмолитическая композиция, способ получения спазмолитической композиции
EP0868915A1 (de) 1997-04-02 1998-10-07 Panacea Biotec Limited Antispasmodische und entzündungshemmende Zusammensetzung, die ein NSAID, Pentifenone und Fenpiverinium enthält
DZ2479A1 (fr) 1997-05-05 2003-02-01 Pfizer Composés inhibiteurs sélectifs de cox-2 anti-inflammatoires et compositions pharmaceutiques les contenant.
RS49982B (sr) * 1997-09-17 2008-09-29 Euro-Celtique S.A., Sinergistička analgetička kombinacija analgetičkog opijata i inhibitora ciklooksigenaze-2
FR2770131A1 (fr) * 1997-10-27 1999-04-30 Union Pharma Scient Appl Nouvelle association pharmaceutique a activite analgesique
TR200102958T2 (tr) 1999-04-14 2002-05-21 Pacific Corporation Siklooksijenaz-2 inhibitörleri olarak 4,5-diaril-3(2H)-furanon türevleri.
US6524623B1 (en) * 1999-11-12 2003-02-25 Milton Hodosh Therapeutic compositions and methods of use thereof
BR0016705A (pt) * 1999-12-22 2002-09-24 Pharmacia Corp Composições de liberação dupla de um inibidor de ciclooxigenase-2
US6306842B1 (en) * 2000-06-02 2001-10-23 Medinox, Inc. Protected forms of a combination of pharmacologically active agents and uses therefor
ATE511844T1 (de) 2000-06-13 2011-06-15 Wyeth Llc Analgetische und entzündungshemmende zusammensetzungen enthaltend celecoxib und ibuprofen

Also Published As

Publication number Publication date
DK1296665T3 (da) 2011-07-18
JP5579958B2 (ja) 2014-08-27
RU2003100874A (ru) 2004-06-27
IL153303A0 (en) 2003-07-06
CN100588395C (zh) 2010-02-10
NZ522957A (en) 2004-03-26
EA011309B1 (ru) 2009-02-27
CN1443067A (zh) 2003-09-17
KR20030019422A (ko) 2003-03-06
US20030216461A1 (en) 2003-11-20
EP1296665B1 (de) 2011-06-08
AU6837701A (en) 2001-12-24
PL206268B1 (pl) 2010-07-30
AU2001268377B2 (en) 2005-07-07
US20050090538A1 (en) 2005-04-28
WO2001095898A1 (en) 2001-12-20
PT1296665E (pt) 2011-07-05
US6924303B2 (en) 2005-08-02
US7754753B2 (en) 2010-07-13
NO20025983L (no) 2003-02-10
CA2411960A1 (en) 2001-12-20
EP1296665A4 (de) 2005-07-27
NO331092B1 (no) 2011-10-03
ZA200209944B (en) 2003-10-08
BR0111767A (pt) 2003-07-08
JP2004503497A (ja) 2004-02-05
HU229440B1 (en) 2013-12-30
HK1059378A1 (zh) 2004-07-02
EP1296665A1 (de) 2003-04-02
HUP0301348A2 (hu) 2003-08-28
NO20025983D0 (no) 2002-12-12
HUP0301348A3 (en) 2005-05-30
PL360469A1 (en) 2004-09-06
ES2365387T3 (es) 2011-10-03
MXPA02012344A (es) 2004-02-26
EA200802070A1 (ru) 2009-06-30
IL153303A (en) 2010-11-30
CA2411960C (en) 2010-10-12
EA200300692A1 (ru) 2003-12-25

Similar Documents

Publication Publication Date Title
BR9907300A (pt) Inibidores do fator xa oxoaza-heterociclila substituìdos
DE602004008098D1 (de) Substituierte 2h-ä1,2,4ütriazoloä4,3-aüpyrazine als gsk-3-inhibitoren
NO20023933D0 (no) Nye forbindelser
DK0778834T3 (da) Bicykliske, heterocykliske diarylforbindelser som inhibitorer af cyclooxygenase-2
AU646230B2 (en) Pharmaceutical compositions and methods for treating the symptoms of overindulgence
TNSN06439A1 (fr) Derives de 2-carbamide -4-phenylthiazole, leur preparation et leur application en therapeutique
DE60334773D1 (de) Formulierungen zur oralen verabreichung von wirkstoffen
ATE511844T1 (de) Analgetische und entzündungshemmende zusammensetzungen enthaltend celecoxib und ibuprofen
EA200501019A1 (ru) Противораковое лекарственное средство, фармацевтическая композиция и способ ингибирования размера опухоли (варианты) на его основе
CO5070569A1 (es) Compuesto de aminoazol o una sal farmaceuticamente aceptable del mismo y medicamento que los contienen
CY1107473T1 (el) Ενα παραγωγο pyridine-n-oxide, και διαδικασια για τη μετατροπη του σε αποτελεσματικες φαρμακευτικες συνθεσεις
ATE161017T1 (de) Inhibitoren gegen die aggregation von blutplättchen
DK0804418T3 (da) Platelataggregationshæmmere
DE60134735D1 (de) Neue neurokinin-antagonisten zum gebrauch als arzneimittel
MXPA02010828A (es) Composicion farmaceutica en capsulas que comprende un antiinflamatorio no esteroideo y un analgesico opiaceo para el manejo del dolor.
NO983511D0 (no) Difenylstilbener som pro-legemidler for COX-2-inhibitorer
HUP0303341A2 (hu) Monoamin-felvétel inhibitora és ezt tartalmazó gyógyszerkészítmények
IL157214A0 (en) Compounds comprising an analgesic molecule linked to a vector that can vectories said molecule through the hematoencephalic barrier and pharmaceutical compositions containing same
PT1250125E (pt) Composicoes farmaceuticas contendo terbinafina
AU2001244999A1 (en) Naphthamide neurokinin antagonists for use as medicaments
SE0004827D0 (sv) Therapeutic compounds
MA30179B1 (fr) Derives de 2-carbamide-4-phenylthiazole, leur preparation et leur application en therapeutique.
MY130814A (en) Oral pharmaceutical compositions containing non-steroidal anti-inflammatory drugs and method for preparing the same
WO2001072735A3 (en) Benzopyranes useful as tnf alpha inhibitors
TH22341A (th) " การรักษาโรคการรวมกันสำหรับการติดเชื้อ hiv"

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1296665

Country of ref document: EP