ATE510558T1 - Verwendung von biologisch aktivem hiv-1 tat, fragmenten oder derivaten davon, zur bestimmung und/oder aktivierung von antigen-präsentierenden zellen, und/oder zur abgabe von cargo-molekülen für impfung und/oder für behandlung von anderen erkrankungen - Google Patents
Verwendung von biologisch aktivem hiv-1 tat, fragmenten oder derivaten davon, zur bestimmung und/oder aktivierung von antigen-präsentierenden zellen, und/oder zur abgabe von cargo-molekülen für impfung und/oder für behandlung von anderen erkrankungenInfo
- Publication number
- ATE510558T1 ATE510558T1 AT02767265T AT02767265T ATE510558T1 AT E510558 T1 ATE510558 T1 AT E510558T1 AT 02767265 T AT02767265 T AT 02767265T AT 02767265 T AT02767265 T AT 02767265T AT E510558 T1 ATE510558 T1 AT E510558T1
- Authority
- AT
- Austria
- Prior art keywords
- vaccination
- tat
- fragments
- diseases
- derivatives
- Prior art date
Links
- 241000713772 Human immunodeficiency virus 1 Species 0.000 title 1
- 210000000612 antigen-presenting cell Anatomy 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 239000012634 fragment Substances 0.000 title 1
- 238000002255 vaccination Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16311—Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
- C12N2740/16322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Endocrinology (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Dermatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01118114A EP1279404A1 (de) | 2001-07-26 | 2001-07-26 | Verwendung von HIV-1 Fragmenten oder Derivaten zur Bestimmung oder Aktivierung von Antigen-präsentierenden Zellen, oder zur Abgabe von Cargo-Molekülen für Impfung oder für Behandlung von anderen Erkrankungen |
| PCT/EP2002/008377 WO2003009867A1 (en) | 2001-07-26 | 2002-07-26 | Use of biologically active hiv-1 tat, fragments or derivates thereof, to target and/or to activate antigen-presenting cells, and/or to deliver cargo molecules for preventive or therapeutic vaccination and/or to treat other diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE510558T1 true ATE510558T1 (de) | 2011-06-15 |
Family
ID=8178141
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02767265T ATE510558T1 (de) | 2001-07-26 | 2002-07-26 | Verwendung von biologisch aktivem hiv-1 tat, fragmenten oder derivaten davon, zur bestimmung und/oder aktivierung von antigen-präsentierenden zellen, und/oder zur abgabe von cargo-molekülen für impfung und/oder für behandlung von anderen erkrankungen |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US7811573B2 (de) |
| EP (2) | EP1279404A1 (de) |
| JP (1) | JP5134183B2 (de) |
| CN (1) | CN1318091C (de) |
| AP (1) | AP2004002986A0 (de) |
| AT (1) | ATE510558T1 (de) |
| AU (1) | AU2002331350B2 (de) |
| BR (1) | BR0211474A (de) |
| CA (1) | CA2455227C (de) |
| DK (1) | DK1425035T3 (de) |
| EA (1) | EA006850B1 (de) |
| ES (1) | ES2367255T3 (de) |
| HU (1) | HUP0400660A2 (de) |
| IL (1) | IL160015A0 (de) |
| MX (1) | MXPA04000287A (de) |
| NZ (1) | NZ531364A (de) |
| OA (1) | OA12701A (de) |
| PL (1) | PL368243A1 (de) |
| WO (1) | WO2003009867A1 (de) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0323840D0 (en) * | 2003-10-10 | 2003-11-12 | Ist Superiore Sanita | Vaccines |
| GB0405480D0 (en) | 2004-03-11 | 2004-04-21 | Istituto Superiore Di Sanito | Novel tat complexes,and vaccines comprising them |
| WO2005090968A1 (en) | 2004-03-16 | 2005-09-29 | Inist Inc. | Tat-based immunomodulatory compositions and methods of their discovery and use |
| US9492400B2 (en) | 2004-11-04 | 2016-11-15 | Massachusetts Institute Of Technology | Coated controlled release polymer particles as efficient oral delivery vehicles for biopharmaceuticals |
| CN100429228C (zh) * | 2005-06-17 | 2008-10-29 | 中国人民解放军第三军医大学第三附属医院 | 重组人a20蛋白及其用途 |
| WO2007070682A2 (en) | 2005-12-15 | 2007-06-21 | Massachusetts Institute Of Technology | System for screening particles |
| JP2009534309A (ja) | 2006-03-31 | 2009-09-24 | マサチューセッツ インスティテュート オブ テクノロジー | 治療剤の標的化送達のためのシステム |
| JP5630998B2 (ja) | 2006-05-15 | 2014-11-26 | マサチューセッツ インスティテュート オブ テクノロジー | 機能的粒子のためのポリマー |
| WO2007150030A2 (en) | 2006-06-23 | 2007-12-27 | Massachusetts Institute Of Technology | Microfluidic synthesis of organic nanoparticles |
| JP2010500407A (ja) * | 2006-08-14 | 2010-01-07 | サイモン・エル・エル・シー | Ｈｉｖ−１の複数の株及びサブタイプを治療及び予防するための組成物及び方法 |
| WO2008098165A2 (en) | 2007-02-09 | 2008-08-14 | Massachusetts Institute Of Technology | Oscillating cell culture bioreactor |
| WO2008124632A1 (en) | 2007-04-04 | 2008-10-16 | Massachusetts Institute Of Technology | Amphiphilic compound assisted nanoparticles for targeted delivery |
| AU2008314647B2 (en) | 2007-10-12 | 2013-03-21 | Massachusetts Institute Of Technology | Vaccine nanotechnology |
| GB0802224D0 (en) | 2008-02-06 | 2008-03-12 | Inst Superiore Di Sanito | Process for the production of vaccine components |
| CN101980738A (zh) | 2008-02-07 | 2011-02-23 | 华盛顿大学 | 圆周气雾设备 |
| EP2106803A1 (de) * | 2008-04-04 | 2009-10-07 | Fondazione Centro San Raffaele del Monte Tabor | Verfahren zum Entwurf von sich überlappenden Peptiden und Verwendungen der Peptide zur Messung von T-Zell Antworten in HIV Patienten |
| JP5576859B2 (ja) | 2008-05-14 | 2014-08-20 | ジャワハーラル ネール センター フォー アドヴァンスド サイエンティフィック リサーチ | Ｔａｔのｄｎａ配列、遺伝子コンストラクト、ワクチンおよびそれらの方法 |
| US8343497B2 (en) | 2008-10-12 | 2013-01-01 | The Brigham And Women's Hospital, Inc. | Targeting of antigen presenting cells with immunonanotherapeutics |
| US8591905B2 (en) | 2008-10-12 | 2013-11-26 | The Brigham And Women's Hospital, Inc. | Nicotine immunonanotherapeutics |
| US8343498B2 (en) | 2008-10-12 | 2013-01-01 | Massachusetts Institute Of Technology | Adjuvant incorporation in immunonanotherapeutics |
| US8277812B2 (en) | 2008-10-12 | 2012-10-02 | Massachusetts Institute Of Technology | Immunonanotherapeutics that provide IgG humoral response without T-cell antigen |
| CN102405057B (zh) | 2009-03-23 | 2016-05-25 | 那尼尔科斯治疗公司 | 用免疫刺激性Hiv Tat衍生物多肽治疗癌症 |
| EP2536838A4 (de) * | 2010-02-18 | 2013-08-21 | Univ Emory | Vektor zur expression von hiv-antigenen und gm-csf sowie entsprechende verfahren zur erzeugung einer immunreaktion |
| US20110287045A1 (en) * | 2010-05-20 | 2011-11-24 | Zongdong Li | Enhanced immune response against infections |
| BR122021002471B8 (pt) | 2011-03-03 | 2022-10-25 | Impel Neuropharma Inc | Dispositivo de distribuição de droga nasal |
| CN103619485B (zh) | 2011-05-09 | 2017-08-08 | 英倍尔药业股份有限公司 | 用于鼻腔药物递送的喷嘴 |
| RU2670488C2 (ru) * | 2012-09-13 | 2018-10-23 | Юниверсите Де Женев | Новые проникающие в клетку пептиды |
| CN103880961A (zh) * | 2012-12-19 | 2014-06-25 | 邱书奇 | 一种诱导免疫耐受融合肽构建 |
| WO2014179228A1 (en) | 2013-04-28 | 2014-11-06 | Impel Neuropharma Inc. | Medical unit dose container |
| RU2695653C2 (ru) | 2013-10-04 | 2019-07-25 | Пин Фарма, Инк. | Иммуностимулирующие полипептидные производные тат вич для применения в лечении рака |
| EP3134107B1 (de) * | 2014-04-24 | 2020-05-27 | Janssen Sciences Ireland Unlimited Company | Verwendung eines hiv-abgeleiteten zubehörproteins zur reaktivierung von latentem hiv |
| NZ741171A (en) | 2015-09-10 | 2022-01-28 | Impel Neuropharma Inc | In-line nasal delivery device |
| JP7150611B2 (ja) | 2016-01-08 | 2022-10-11 | ジオバックス・インコーポレイテッド | 腫瘍関連抗原に対する免疫応答を誘起するための組成物及び方法 |
| CN105535937B (zh) * | 2016-03-11 | 2018-03-13 | 刘红 | 一种用于治疗类风湿性关节炎的皮下注射用原位凝胶 |
| WO2018050225A1 (en) * | 2016-09-15 | 2018-03-22 | Yu Di | T-cell immunotherapy |
| US11311612B2 (en) | 2017-09-19 | 2022-04-26 | Geovax, Inc. | Compositions and methods for generating an immune response to treat or prevent malaria |
| KR102131898B1 (ko) * | 2017-10-31 | 2020-07-08 | 주식회사 노벨티노빌리티 | Scf 및 갈렉틴-1을 표적으로 하는 이중표적항체 및 그 용도 |
| US11571532B2 (en) | 2017-11-21 | 2023-02-07 | Impel Pharmaceuticals Inc. | Intranasal device with dip tube |
| WO2019104192A1 (en) | 2017-11-21 | 2019-05-31 | Impel Neuropharma, Inc. | Intranasal device with inlet interface |
| CN111936140A (zh) | 2018-01-05 | 2020-11-13 | 英倍尔药业股份有限公司 | 通过精密鼻装置的双氢麦角胺的鼻内递送 |
| CA3087698A1 (en) | 2018-01-05 | 2019-07-11 | Impel Neuropharma, Inc. | Intranasal delivery of olanzapine by precision olfactory device |
| EP3823607A4 (de) | 2018-07-19 | 2022-04-06 | Impel NeuroPharma Inc. | Atemwegsverabreichung von levodopa- und dopa-decarboxylase-inhibitoren zur behandlung von morbus parkinson |
| EA202191856A1 (ru) | 2019-01-03 | 2021-09-02 | Импел Ньюрофарма, Инк. | Устройство для назальной доставки лекарственных средств |
| JP7317379B2 (ja) * | 2019-01-04 | 2023-07-31 | 国立大学法人京都大学 | 潰瘍性大腸炎及び原発性硬化性胆管炎の検査方法 |
| CN114025816A (zh) | 2019-05-17 | 2022-02-08 | 英倍尔药业股份有限公司 | 一次性鼻腔给送装置 |
| TW202112394A (zh) * | 2019-06-06 | 2021-04-01 | 日商電化股份有限公司 | 以肽核酸為基礎之佐劑 |
| CN111450082A (zh) * | 2020-04-26 | 2020-07-28 | 天津大学 | 一种系统性红斑狼疮治疗纳米颗粒的合成方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9720585D0 (en) * | 1997-09-26 | 1997-11-26 | Smithkline Beecham Biolog | Vaccine |
| IT1297090B1 (it) * | 1997-12-01 | 1999-08-03 | Barbara Ensoli | Tat di hiv-1 o suoi derivati, da soli od in combinazione, a scopo vaccinale, profilattico e terapeutico, contro l'aids i tumori e le |
| FI105105B (fi) * | 1998-02-27 | 2000-06-15 | Finnish Immunotechnology Ltd O | Itsereplikoiva DNA-vektori immunisoimiseksi HIV:ta vastaan |
| AU4082300A (en) * | 1999-06-21 | 2001-01-09 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Hiv tat peptides and multiple peptide conjugate system |
| CA2376992A1 (en) | 1999-06-29 | 2001-01-04 | Smithkline Beecham Biologicals S.A. | Use of cpg as an adjuvant for hiv vaccine |
| EP1246647B1 (de) | 1999-08-12 | 2010-04-28 | InIst, Inc. | Nicht-immunsuppresives hiv tat-protein |
| WO2001019393A1 (en) * | 1999-09-13 | 2001-03-22 | Cornell Research Foundation, Inc. | Delivering to eucaryotic cells bacterial proteins that are secreted via type iii secretion systems |
| KR20070073987A (ko) | 2000-01-31 | 2007-07-10 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | Ｈｉｖ에 대한 예방 또는 치료용 면역화를 위한 백신 |
| AU2001234616A1 (en) | 2000-01-31 | 2001-08-07 | Vic Jira | Vaccine composition, process and methods |
| US6544780B1 (en) | 2000-06-02 | 2003-04-08 | Genphar, Inc. | Adenovirus vector with multiple expression cassettes |
| AT410635B (de) | 2000-10-18 | 2003-06-25 | Cistem Biotechnologies Gmbh | Vakzin-zusammensetzung |
-
2001
- 2001-07-26 EP EP01118114A patent/EP1279404A1/de not_active Withdrawn
-
2002
- 2002-07-26 EP EP02767265A patent/EP1425035B1/de not_active Expired - Lifetime
- 2002-07-26 ES ES02767265T patent/ES2367255T3/es not_active Expired - Lifetime
- 2002-07-26 EA EA200400227A patent/EA006850B1/ru not_active IP Right Cessation
- 2002-07-26 CA CA2455227A patent/CA2455227C/en not_active Expired - Fee Related
- 2002-07-26 US US10/485,180 patent/US7811573B2/en not_active Expired - Fee Related
- 2002-07-26 AT AT02767265T patent/ATE510558T1/de not_active IP Right Cessation
- 2002-07-26 DK DK02767265.8T patent/DK1425035T3/da active
- 2002-07-26 MX MXPA04000287A patent/MXPA04000287A/es not_active Application Discontinuation
- 2002-07-26 WO PCT/EP2002/008377 patent/WO2003009867A1/en active IP Right Grant
- 2002-07-26 HU HU0400660A patent/HUP0400660A2/hu unknown
- 2002-07-26 NZ NZ531364A patent/NZ531364A/en not_active IP Right Cessation
- 2002-07-26 IL IL16001502A patent/IL160015A0/xx not_active IP Right Cessation
- 2002-07-26 JP JP2003515259A patent/JP5134183B2/ja not_active Expired - Fee Related
- 2002-07-26 PL PL02368243A patent/PL368243A1/xx unknown
- 2002-07-26 AP APAP/P/2004/002986A patent/AP2004002986A0/en unknown
- 2002-07-26 BR BR0211474-7A patent/BR0211474A/pt not_active IP Right Cessation
- 2002-07-26 AU AU2002331350A patent/AU2002331350B2/en not_active Ceased
- 2002-07-26 CN CNB028146581A patent/CN1318091C/zh not_active Expired - Fee Related
- 2002-07-26 OA OA1200400015A patent/OA12701A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1318091C (zh) | 2007-05-30 |
| US20050036985A1 (en) | 2005-02-17 |
| AP2004002986A0 (en) | 2004-03-31 |
| EP1425035A1 (de) | 2004-06-09 |
| HUP0400660A2 (hu) | 2005-01-28 |
| EP1279404A1 (de) | 2003-01-29 |
| CA2455227A1 (en) | 2003-02-06 |
| OA12701A (en) | 2006-06-23 |
| BR0211474A (pt) | 2004-07-13 |
| CA2455227C (en) | 2012-01-24 |
| PL368243A1 (en) | 2005-03-21 |
| US7811573B2 (en) | 2010-10-12 |
| IL160015A0 (en) | 2004-06-20 |
| CN1533284A (zh) | 2004-09-29 |
| NZ531364A (en) | 2005-12-23 |
| AU2002331350B2 (en) | 2008-06-12 |
| EA006850B1 (ru) | 2006-04-28 |
| MXPA04000287A (es) | 2005-03-07 |
| JP5134183B2 (ja) | 2013-01-30 |
| WO2003009867A1 (en) | 2003-02-06 |
| DK1425035T3 (da) | 2011-08-29 |
| ES2367255T3 (es) | 2011-10-31 |
| EA200400227A1 (ru) | 2004-06-24 |
| EP1425035B1 (de) | 2011-05-25 |
| JP2005505520A (ja) | 2005-02-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE510558T1 (de) | Verwendung von biologisch aktivem hiv-1 tat, fragmenten oder derivaten davon, zur bestimmung und/oder aktivierung von antigen-präsentierenden zellen, und/oder zur abgabe von cargo-molekülen für impfung und/oder für behandlung von anderen erkrankungen | |
| CY1119951T1 (el) | Συνθεσεις για αυξηση δραστηριοτητας τελομερασης και αγωγη λοιμωξης hiv | |
| DE502005010615D1 (de) | Mittel zur behandlung von entzündlichen erkrankungen | |
| ATE518841T1 (de) | Herstellung und verwendung von arylalkylsäurederivaten zur behandlung von obesitas | |
| DE60023128D1 (de) | Pyrazolecarboxamide zur behandlung von fettleibigkeit und anderen erkrankungen | |
| DE602004017588D1 (de) | 2-phenoxy- und 2-phenylsulfanyl-benzenesulfonamid derivate mit ccr3 antagonistischer aktivität zur behandlung von asthma und anderen entzündlichen oder immunologischen erkrankungen | |
| DE602004002585D1 (de) | VERWENDUNG EINER PHARMAZEUTISCHEN FORMULIERUNG ENTHALTEND MILCHSÄURE ODER LAKTAT UND kALIUM ZUR BEHANDLUNG VON HIRNÖDEM UND VERLETZUNGEN DES GEHIRNS | |
| WO2007024899A3 (en) | Use of glp-1, glp-1 derivatives or glp-1 fragments for skin regeneration, stimulation of hair growth, or treatment of diabetes | |
| DE60327622D1 (de) | Kombinierte antitachykardie - schrittmacher und hochspannungstherapie zur behandlung von ventrikulären arrhythmien | |
| DE60138549D1 (de) | Topische gel-abgabesysteme zur behandlung von hauterkrankungen | |
| ATE389649T1 (de) | Substituierte amin-derivate und deren verwendung zur behandlung von angionese-bedingten erkrankungen | |
| DE69919403D1 (de) | Verwendung von nikotinsäurederivate zur behandlung von dna-schäden bei hautzellen | |
| DE60230869D1 (de) | 4-(phenylpiperazinylmethyl) benzamidderivate und deren verwendung zur behandlung von schmerzen, angst oder gastrointestinalen störungen | |
| ATE415962T1 (de) | Verwendung von asiatsäure oder asiaticosid zur behandlung von krebs | |
| CY1113116T1 (el) | Υποκατεστημενες 4-αμινοκυκλοεξανολες | |
| DE112004000961D2 (de) | Verwendung von Wirksubstanzen zur Vorbeugung oder Behandlung von Viruserkrankungen sowie Testsystem zum Auffinden solcher Wirksubstanzen | |
| TR200100637T2 (tr) | Yeni doğal ürün türevleri | |
| DE60314003D1 (de) | 4-(phenylpiperazinylmethyl)benzamidderivate und deren verwendung zur behandlung von schmerzen oder gastrointestinalen erkrankungen | |
| DE60224004D1 (de) | Verwendung von il-18 hemmern zur behandlung und/oder prävention von herzkrankheiten | |
| DE60213234D1 (de) | 4-(penylpiperidin-4-ylidenmethyl)benzamidderivate und deren verwendung zur behandlung von schmerzen, angstzuständen oder erkrankungen des magen-darm-trakts | |
| ATE291586T1 (de) | Humanes antibiotisches protein | |
| ATE330596T1 (de) | Verwendung von 3-bezoylphenylessigsäure-derivaten zur behandlung von netzhauterkrankungen | |
| ATE491442T1 (de) | 1-phenyl-2- dimethylaminomethylcyclohexanverbindungen zur therapie von depressiven symptomatiken, schmerz und inkontinenz | |
| DE19681032D2 (de) | Gentherapeutisches Nukleinsäurekonstrukt, seine Herstellung und Verwendung zur Behandlung von Herzerkrankungen | |
| DE60202684D1 (de) | Pflanzenpräparat zur behandlung und heilung von bronchialen respiratorischen schwierigkeiten |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |