ATE502301T1 - Quinacridon markierungsreagenzien für fluoreszenz-nachweis von biologischen materialen - Google Patents

Quinacridon markierungsreagenzien für fluoreszenz-nachweis von biologischen materialen

Info

Publication number
ATE502301T1
ATE502301T1 AT02740872T AT02740872T ATE502301T1 AT E502301 T1 ATE502301 T1 AT E502301T1 AT 02740872 T AT02740872 T AT 02740872T AT 02740872 T AT02740872 T AT 02740872T AT E502301 T1 ATE502301 T1 AT E502301T1
Authority
AT
Austria
Prior art keywords
sub
sup
group
quinacridone
nitro
Prior art date
Application number
AT02740872T
Other languages
English (en)
Inventor
John Anthony Smith
Original Assignee
Ge Healthcare Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Uk Ltd filed Critical Ge Healthcare Uk Ltd
Application granted granted Critical
Publication of ATE502301T1 publication Critical patent/ATE502301T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B48/00—Quinacridones
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B15/00—Acridine dyes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
AT02740872T 2001-06-04 2002-05-30 Quinacridon markierungsreagenzien für fluoreszenz-nachweis von biologischen materialen ATE502301T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0113434.5A GB0113434D0 (en) 2001-06-04 2001-06-04 Quinacridone derivatives as labels for fluorescence detection of biological materials
PCT/GB2002/002537 WO2002099432A2 (en) 2001-06-04 2002-05-30 Quinacridone labelling reagents for fluorescence detection of biological materials

Publications (1)

Publication Number Publication Date
ATE502301T1 true ATE502301T1 (de) 2011-04-15

Family

ID=9915774

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02740872T ATE502301T1 (de) 2001-06-04 2002-05-30 Quinacridon markierungsreagenzien für fluoreszenz-nachweis von biologischen materialen

Country Status (9)

Country Link
US (1) US7335771B2 (de)
EP (1) EP1399742B1 (de)
JP (1) JP4317444B2 (de)
AT (1) ATE502301T1 (de)
AU (1) AU2002314302B2 (de)
CA (1) CA2449409C (de)
DE (1) DE60239458D1 (de)
GB (2) GB0113434D0 (de)
WO (1) WO2002099432A2 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2398123B (en) * 2002-04-19 2005-03-02 Amersham Biosciences Uk Ltd Methods for measuring enzyme activity
GB0208989D0 (en) 2002-04-19 2002-05-29 Amersham Biosciences Uk Ltd Methods for measuring enzyme activity
GB0217562D0 (en) * 2002-07-30 2002-09-11 Amersham Biosciences Uk Ltd Site-specific labelling of proteins using acridone and quinacridone lifetime dyes
GB0317743D0 (en) * 2003-07-30 2003-09-03 Amersham Biosciences Uk Ltd Method for measuring aromatase activity
KR20070043810A (ko) * 2004-06-29 2007-04-25 시바 스페셜티 케미칼스 홀딩 인크. 형광 퀴나크리돈
GB0421693D0 (en) 2004-09-30 2004-11-03 Amersham Biosciences Uk Ltd Method for measuring binding of a test compound to a G-protein coupled receptor
GB0505777D0 (en) * 2005-03-22 2005-04-27 Amersham Biosciences Uk Ltd Enzyme detection method and reagent
EP1790695B1 (de) 2005-11-28 2009-02-18 Agfa Graphics N.V. Nichtwässerige Chinakridondispersionen unter Verwendung von Dispersionssynergisten
US20090186200A1 (en) * 2006-05-22 2009-07-23 Brian Thompson 2,5-di(methoxyanilino) terephthalic acid polymorphs and quinacridones realized therefrom
WO2008030120A1 (en) * 2006-09-07 2008-03-13 Auckland Uniservices Limited A method for the fluorescent detection of nitroreductase activity using nitro-substituted aromatic compounds
EP2268656A1 (de) * 2008-03-14 2011-01-05 Assaymetrics Limited Fluorogene peptide und verfahren zu ihrer herstellung
EP2316890A1 (de) * 2009-11-03 2011-05-04 Agfa-Gevaert Herstellung und Dispersion von oberflächenmodifizierten Farbpigmenten
CA2746891A1 (en) * 2010-07-19 2012-01-19 Universite De Montreal Fluorescent markers and use thereof for labelling specific protein targets
JP2014508537A (ja) 2011-03-25 2014-04-10 アルマック・サイエンシーズ・（スコットランド）・リミテッド 酵素アッセイ
CN102276600B (zh) * 2011-04-22 2012-11-14 华东理工大学 喹吖啶酮衍生物及其用途
GB2511110A (en) * 2013-02-25 2014-08-27 Sudarshan Chemical Ind Ltd Pigments
US20160289728A1 (en) * 2013-11-21 2016-10-06 The University Of Tokyo Method for detecting fluorescence or absorbance, method for suppressing background, method for measuring adp, method for measuring activity of adp-synthesizing enzyme, and method for measuring activity of glucosyltransferase
US9701667B2 (en) 2014-05-05 2017-07-11 University Of Ottawa Coumarin-based fluorogenic agents and uses thereof for specific protein labelling
US10591485B2 (en) 2015-01-23 2020-03-17 University Of Ottawa Peptide tags for fluorescent labelling of proteins
JP2017020896A (ja) * 2015-07-10 2017-01-26 国立大学法人北陸先端科学技術大学院大学 Ｎ末端標識剤、これを用いた蛍光標識タンパク質及びその製造方法
US9958452B2 (en) 2015-12-14 2018-05-01 University Of Ottawa Highly fluorogenic protein labelling agents
EP3246969B1 (de) 2016-05-17 2018-12-12 Samsung SDI Co., Ltd. Separator für eine wiederaufladbare batterie und wiederaufladbare lithiumbatterie damit
US11414387B2 (en) 2017-11-20 2022-08-16 Stingthera, Inc. Oxoacridinyl acetic acid derivatives and methods of use
EP3713920A4 (de) 2017-11-20 2021-04-14 Silicon Swat, Inc. Oxoacridinylessigsäurederivate und verfahren zur verwendung
CN112794813B (zh) * 2020-12-30 2022-04-26 四川大学华西医院 一种用于荧光标记的环丁烯衍生物
CN114605405B (zh) * 2022-03-09 2023-09-05 吉林大学 一种基于喹吖啶酮骨架的细胞脂滴荧光成像探针及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61168666A (ja) * 1985-01-21 1986-07-30 Dainippon Ink & Chem Inc 顔料組成物
EP0673979B1 (de) * 1994-03-25 2000-08-30 Ciba SC Holding AG Cyaniminogruppen enthaltende Fluoreszenzfarbstoffe
US5713999A (en) * 1996-04-29 1998-02-03 Bayer Corporation Incorporation of pigment derivatives in quinacridone processes
GB0208989D0 (en) * 2002-04-19 2002-05-29 Amersham Biosciences Uk Ltd Methods for measuring enzyme activity

Also Published As

Publication number Publication date
GB0113434D0 (en) 2001-07-25
CA2449409A1 (en) 2002-12-12
GB0326464D0 (en) 2003-12-17
US7335771B2 (en) 2008-02-26
GB2391550B (en) 2005-02-02
EP1399742B1 (de) 2011-03-16
EP1399742A2 (de) 2004-03-24
US20040171014A1 (en) 2004-09-02
WO2002099432A3 (en) 2003-05-01
DE60239458D1 (de) 2011-04-28
JP2005501228A (ja) 2005-01-13
AU2002314302B2 (en) 2006-02-23
JP4317444B2 (ja) 2009-08-19
WO2002099432A2 (en) 2002-12-12
CA2449409C (en) 2012-07-17
GB2391550A (en) 2004-02-11

Similar Documents

Publication Publication Date Title
ATE502301T1 (de) Quinacridon markierungsreagenzien für fluoreszenz-nachweis von biologischen materialen
WO2002099424A3 (en) Acridone derivatives as labels for fluorescence detection of target materials
DK1086179T3 (da) Energioverførselsassaymetode og reagens
US5688648A (en) Probes labelled with energy transfer coupled dyes
ATE522580T1 (de) Cyaninfarbstoffe als markieragenzien
US5853992A (en) Cyanine dyes with high-absorbance cross section as donor chromophores in energy transfer labels
ATE236996T1 (de) Sätze von, mit fluoreszierenden energieübertragungsverbindungen, markierten primern und deren verwendung in mehrkomponentenanalyse
DK1105360T3 (da) Identifikation af forbindelse-protein-interaktioner ved anvendelse af biblioteker af protein-nukleinsyrefusionsmolekyler
CY1111278T1 (el) Συστημα ασφαλειας
ATE331810T1 (de) Kits und verfahren zur detektion von zielnukleinsäuren unter verwendung von markernukleinsäuren
DE60334639D1 (de) Kassetten mit heterozyklischenfret-farbstoffen zur markierung biologischer moleküle und ihre verwendung beider sequenzierung von dna
HK1062014A1 (en) Labelling reagents, method for synthesis of said reagents and methods for detecting biological molecules
ATE460670T1 (de) Reagenzien sowie ein verfahren zur sättigungsmarkierung von proteinen
CA2450581A1 (en) Cardiovascular safety assay
ATE290607T1 (de) Floureszenzintensitäts-test für eine protein- oder peptidbindung an nukleinsäuren
Kapuscinski et al. Spectral properties of fluorochromes used in flow cytometry
CY1105034T1 (el) Ελαχιστοι υποκινητες και οι χρησεις τους
NO20004753L (no) Fluorescent assay for topoisomerase-inhibitorer
US6979575B1 (en) Fluorochromes for labelling biomolecules and polymer particles and bioanalytical and screening methods based thereon
DE60136572D1 (de) Detektion von rpob sequenzen von mycobacterium tuberculosis

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties