ATE460670T1 - Reagenzien sowie ein verfahren zur sättigungsmarkierung von proteinen - Google Patents

Reagenzien sowie ein verfahren zur sättigungsmarkierung von proteinen

Info

Publication number
ATE460670T1
ATE460670T1 AT02747568T AT02747568T ATE460670T1 AT E460670 T1 ATE460670 T1 AT E460670T1 AT 02747568 T AT02747568 T AT 02747568T AT 02747568 T AT02747568 T AT 02747568T AT E460670 T1 ATE460670 T1 AT E460670T1
Authority
AT
Austria
Prior art keywords
protein
dye
labeled
matched
group
Prior art date
Application number
AT02747568T
Other languages
English (en)
Inventor
K Williams
T Stone
A C Simmonds
A C Sweet
S J Fowler
Original Assignee
Ge Healthcare Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Uk Ltd filed Critical Ge Healthcare Uk Ltd
Application granted granted Critical
Publication of ATE460670T1 publication Critical patent/ATE460670T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/13—Labelling of peptides
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/02—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B67/00—Influencing the physical, e.g. the dyeing or printing properties of dyestuffs without chemical reactions, e.g. by treating with solvents grinding or grinding assistants, coating of pigments or dyes; Process features in the making of dyestuff preparations; Dyestuff preparations of a special physical nature, e.g. tablets, films
    • C09B67/0033—Blends of pigments; Mixtured crystals; Solid solutions
    • C09B67/0034—Mixtures of two or more pigments or dyes of the same type
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6806—Determination of free amino acids
    • G01N33/6812—Assays for specific amino acids
    • G01N33/6815—Assays for specific amino acids containing sulfur, e.g. cysteine, cystine, methionine, homocysteine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Indole Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT02747568T 2002-07-08 2002-07-08 Reagenzien sowie ein verfahren zur sättigungsmarkierung von proteinen ATE460670T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/GB2002/003142 WO2004005933A1 (en) 2002-07-08 2002-07-08 Reagents and a method for saturation labelling of proteins

Publications (1)

Publication Number Publication Date
ATE460670T1 true ATE460670T1 (de) 2010-03-15

Family

ID=30011660

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02747568T ATE460670T1 (de) 2002-07-08 2002-07-08 Reagenzien sowie ein verfahren zur sättigungsmarkierung von proteinen

Country Status (10)

Country Link
US (1) US7511155B2 (de)
EP (1) EP1520176B1 (de)
JP (1) JP4318180B2 (de)
CN (1) CN1307263C (de)
AT (1) ATE460670T1 (de)
AU (1) AU2002317958B2 (de)
CA (1) CA2491692C (de)
DE (1) DE60235652D1 (de)
ES (1) ES2341946T3 (de)
WO (1) WO2004005933A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006062222A1 (ja) * 2004-12-06 2006-06-15 National Institute Of Advanced Industrial Science And Technology タンパク質の分離方法及び染色方法、並びにこれらの方法に用いるタンパク質染色液及びタンパク質染色用キット
WO2010010158A1 (en) 2008-07-23 2010-01-28 Leibniz-Institut Für Pflanzenbiochemie (Ipb) Qualitative and/or quantitative determination of a proteinaceous molecule in a plurality of samples
KR20110104937A (ko) * 2008-12-02 2011-09-23 도꾸리쯔교세이호징 가가꾸 기쥬쯔 신꼬 기꼬 방향족 술폰산 화합물을 이용한 신규 클리어 네이티브 전기 영동법
US8729276B2 (en) 2009-04-17 2014-05-20 Korea Institute Of Science And Technology Cyanine compound for labeling biomolecule and preparation method thereof
KR101903208B1 (ko) * 2010-12-28 2018-10-01 추가이 세이야쿠 가부시키가이샤 동물 세포의 배양 방법
CN103113283A (zh) * 2013-01-22 2013-05-22 天津理工大学 一种含给电子基团半菁蓝素温敏分子光学探针的制备方法
CN103113282A (zh) * 2013-01-22 2013-05-22 天津理工大学 一种含吸电子基团半菁蓝素温敏分子光学探针的制备方法
DE102022131451A1 (de) 2022-11-28 2024-05-29 Carl Zeiss Microscopy Gmbh Verfahren und Vorrichtung zum Bestimmen einer Signal-Zusammensetzung von Signalfolgen einer Bildfolge
DE102022131449A1 (de) 2022-11-28 2024-05-29 Carl Zeiss Microscopy Gmbh Verfahren und Vorrichtung zum Aufbereiten von Daten zum Identifizieren von Analyten
DE102022131448A1 (de) 2022-11-28 2024-05-29 Carl Zeiss Microscopy Gmbh Verfahren und Vorrichtung zum Aufbereiten von Daten zum Identifizieren von Analyten
DE102022131444A1 (de) 2022-11-28 2024-05-29 Carl Zeiss Microscopy Gmbh Verfahren zum Identifizieren von Analyten in einer Bildfolge
DE102022131447A1 (de) 2022-11-28 2024-05-29 Carl Zeiss Microscopy Gmbh Verfahren und Vorrichtung zum Aufbereiten von Daten zum Identifizieren von Analyten
DE102022131446A1 (de) 2022-11-28 2024-05-29 Carl Zeiss Microscopy Gmbh Verfahren und Vorrichtung zum Aufbereiten von Daten zum Identifizieren von Analyten
DE102022131450A1 (de) 2022-11-28 2024-05-29 Carl Zeiss Microscopy Gmbh Verfahren und Vorrichtung zum Aufbereiten von Daten zum Identifizieren von Analyten
DE102022131445A1 (de) 2022-11-28 2024-05-29 Carl Zeiss Microscopy Gmbh Verfahren und Vorrichtung zum Aufbereiten von Daten zum Identifizieren von Analyten

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5268486A (en) * 1986-04-18 1993-12-07 Carnegie-Mellon Unversity Method for labeling and detecting materials employing arylsulfonate cyanine dyes
US6127134A (en) * 1995-04-20 2000-10-03 Carnegie Mellon University Difference gel electrophoresis using matched multiple dyes
CA2308125A1 (en) * 1997-10-10 1999-04-22 Cytovia, Inc. Novel fluorescent reporter molecules and their applications including assays for caspases
DE60010956T2 (de) * 1999-03-25 2005-06-16 Nisshinbo Industries, Inc. Carbodiimidverbindungen, die eine fluoreszierende Gruppe enthalten, deren Vorstufen und Verfahren zu deren Herstellung
US6114350A (en) * 1999-04-19 2000-09-05 Nen Life Science Products, Inc. Cyanine dyes and synthesis methods thereof
EP2325263B1 (de) * 2000-09-29 2013-01-23 Life Technologies Corporation Modifizierte Carbocyaninfarbstoffe und deren Konjugate
JP2003048879A (ja) * 2001-05-31 2003-02-21 Nisshinbo Ind Inc 蛍光性基含有カルボジイミド化合物及び該化合物の製造方法
US8227621B2 (en) * 2005-06-30 2012-07-24 Li-Cor, Inc. Cyanine dyes and methods of use

Also Published As

Publication number Publication date
US20050233462A1 (en) 2005-10-20
AU2002317958B2 (en) 2007-07-12
WO2004005933A1 (en) 2004-01-15
AU2002317958A1 (en) 2004-01-23
CA2491692A1 (en) 2004-01-15
US7511155B2 (en) 2009-03-31
ES2341946T3 (es) 2010-06-30
DE60235652D1 (de) 2010-04-22
EP1520176A1 (de) 2005-04-06
EP1520176B1 (de) 2010-03-10
JP4318180B2 (ja) 2009-08-19
CN1307263C (zh) 2007-03-28
CA2491692C (en) 2010-12-07
CN1650168A (zh) 2005-08-03
JP2005532543A (ja) 2005-10-27

Similar Documents

Publication Publication Date Title
ATE460670T1 (de) Reagenzien sowie ein verfahren zur sättigungsmarkierung von proteinen
DK1141399T3 (da) Sekventeringsfremgangsmåde under anvendelse af forstörrelsesmærker
ATE420061T1 (de) 13c,15n,2h markierte proteine zur nmr strukturbestimmung und deren herstellung
DE50012021D1 (de) Nucleinsauremoleküle mit spezifischer erkennung von nativem prpsc, herstellung und verwendung
CO4810232A1 (es) Citoquinas de mamiferos y sus secuencias codificadoras
ATE470150T1 (de) Methode zum schnellen identifizieren von kleinen organischen liganden
FI962247A (fi) Uudet apoptoosia muuntavat proteiinit, niitä koodaava DNA ja näiden käyttömenetelmät
ATE326984T1 (de) Verfahren zur verbindung von molekularen substanzen
BR9811675A (pt) Genes isolados para proteìna da membrana de célula dentrìtica
IL162568A0 (en) fluorescent protein from aequorea coerulscens and uses thereof
DK1457482T3 (da) Stabil isotop-mærket aminosyre, fremgangsmåde til integrering af samme i målprotein, fremgangsmåde til NMR-strukturanalyse af protein
CU23302A1 (es) Medio de cultivo selectivo para el aislamiento y detecciã"n de especies del gã0/00nero streptococcus
ATE483161T1 (de) Zur vereinfachung komplexer peptidgemische geeignete verfahren und kits
BR0213779A (pt) Molécula de ácido nucleico isolada, vetor, célula hospedeira, e, método para a preparação de um composto de quìmica fina
SE0300586D0 (sv) Diagnosis of autism
NZ596259A (en) Biologically produced cyclic affinity tags comprising cyclized streptavidin binding sequence
ATE187162T1 (de) Verfahren zur herstellung von alpha,omega- diaminosäuren abgeleiteten harnstoffen
ECSP982602A (es) Citoquinas de mamiferos, reactivos relacionados
Zaia Improvements in the tandem mass spectrometric sequencing of peptides and chemically modified peptides.
RU94002991A (ru) Способ идентификации мумиеподобных веществ
ATE291641T1 (de) Verfahren zur erstellung von profilen der differentialen proteinexpression
DE60000965D1 (de) Pseudopeptid, verfahren zur herstellung, reagenz und verwendungen

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties