ATE290607T1 - Floureszenzintensitäts-test für eine protein- oder peptidbindung an nukleinsäuren - Google Patents
Floureszenzintensitäts-test für eine protein- oder peptidbindung an nukleinsäurenInfo
- Publication number
- ATE290607T1 ATE290607T1 AT99961232T AT99961232T ATE290607T1 AT E290607 T1 ATE290607 T1 AT E290607T1 AT 99961232 T AT99961232 T AT 99961232T AT 99961232 T AT99961232 T AT 99961232T AT E290607 T1 ATE290607 T1 AT E290607T1
- Authority
- AT
- Austria
- Prior art keywords
- fluorophore
- binding
- compound
- labeled compound
- protein
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6804—Nucleic acid analysis using immunogens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Pathology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Hematology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/224,505 US6294333B1 (en) | 1998-12-31 | 1998-12-31 | Fluorescent intensity assay for protein or peptide binding to nucleic acids |
PCT/IB1999/002066 WO2000040753A1 (en) | 1998-12-31 | 1999-12-29 | Fluorescent intensity assay for protein or peptide binding to nucleic acids |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE290607T1 true ATE290607T1 (de) | 2005-03-15 |
Family
ID=22840991
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99961232T ATE290607T1 (de) | 1998-12-31 | 1999-12-29 | Floureszenzintensitäts-test für eine protein- oder peptidbindung an nukleinsäuren |
Country Status (9)
Country | Link |
---|---|
US (1) | US6294333B1 (de) |
EP (1) | EP1141392B1 (de) |
JP (1) | JP3959438B2 (de) |
AT (1) | ATE290607T1 (de) |
AU (1) | AU771451B2 (de) |
CA (1) | CA2358065C (de) |
DE (1) | DE69924147T2 (de) |
TW (1) | TWI235766B (de) |
WO (1) | WO2000040753A1 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6858390B2 (en) | 1998-12-31 | 2005-02-22 | Ingeneus Corporation | Aptamers containing sequences of nucleic acid or nucleic acid analogues bound homologously, or in novel complexes |
US7052844B2 (en) * | 1999-12-21 | 2006-05-30 | Ingeneus, Inc. | Purification of DS-DNA using heteropolymeric capture probes and a triplex, quadruplex or homologous duplex binding mechanism |
US20030170659A1 (en) * | 2000-01-24 | 2003-09-11 | Ingeneus Corporation | Electrical treatment of binding media to encourage, discourage and/or study biopolymer binding |
US6982147B2 (en) * | 2000-01-24 | 2006-01-03 | Ingeneus Corporation | Apparatus for assaying biopolymer binding by means of multiple measurements under varied conditions |
US6613524B1 (en) | 2000-01-24 | 2003-09-02 | Ingeneus Corporation | Amperometric affinity assay and electrically stimulated complexes of nucleic acids |
US6544746B2 (en) | 2001-08-13 | 2003-04-08 | St. Louis University | Rapid and sensitive proximity-based assay for the detection and quantification of DNA binding proteins |
US7172865B2 (en) | 2001-08-13 | 2007-02-06 | Saint Louis University | Rapid and sensitive assay for the detection and quantification of coregulators of nucleic acid binding factors |
JP2003284552A (ja) * | 2002-03-28 | 2003-10-07 | Hitachi Software Eng Co Ltd | イオン性高分子同定用高分子チップ及びイオン性高分子の同定方法 |
US20040180345A1 (en) * | 2003-03-14 | 2004-09-16 | Ingeneus Corporation | Pre-incubation method to improve signal/noise ratio of nucleic acid assays |
JP3916086B2 (ja) * | 2004-06-29 | 2007-05-16 | ソニー株式会社 | ハイブリダイゼーションなどの相互作用を検出する方法及び検出部、該検出部を備えるバイオアッセイ用基板、ハイブリダイゼーションなどの相互作用を検出する装置、並びに試薬キット |
US8486622B2 (en) * | 2004-09-24 | 2013-07-16 | Ingeneus Inc. | Genomic assay |
WO2010088282A1 (en) * | 2009-01-30 | 2010-08-05 | Rgo Biosciences Llc | Nucleic acid binding assays |
KR101341640B1 (ko) * | 2010-02-05 | 2013-12-16 | 한국전자통신연구원 | 단백질 미세 구조 분석 방법 및 단백질 미세 구조 분석용 어레이 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3379179D1 (en) | 1982-09-10 | 1989-03-16 | Welsh Nat School Med | Immunological procedure for quantifying substances |
US4743535A (en) * | 1984-11-07 | 1988-05-10 | Miles Inc. | Hybridization assay employing labeled probe and anti-hybrid |
US5187106A (en) | 1984-08-30 | 1993-02-16 | Orbit Medical Systems, Inc. | Method and apparatus for homogeneous fluorescence measurements |
US5726014A (en) | 1991-06-27 | 1998-03-10 | Genelabs Technologies, Inc. | Screening assay for the detection of DNA-binding molecules |
US5783384A (en) | 1992-01-13 | 1998-07-21 | President And Fellows Of Harvard College | Selection of binding-molecules |
US5445935A (en) * | 1992-11-23 | 1995-08-29 | Royer; Catherine A. | Quantitative detection of macromolecules with fluorescent oligonucleotides |
US5747247A (en) * | 1994-07-25 | 1998-05-05 | The Regents Of The University Of California | Spectroscopic helicase assay |
US6107029A (en) | 1996-07-31 | 2000-08-22 | Message Pharmaceticals, Inc. | Universal method for detecting interactions between RNA molecules and RNA binding proteins |
AU7847798A (en) | 1996-12-13 | 1998-07-03 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Fluorescent nucleotide analog hairpin formation for detection of nuclei c acid hybridization |
US5846729A (en) | 1997-02-27 | 1998-12-08 | Lorne Park Research, Inc. | Assaying nucleotides in solution using a fluorescent intensity quenching effect |
-
1998
- 1998-12-31 US US09/224,505 patent/US6294333B1/en not_active Expired - Lifetime
-
1999
- 1999-12-29 DE DE69924147T patent/DE69924147T2/de not_active Expired - Fee Related
- 1999-12-29 WO PCT/IB1999/002066 patent/WO2000040753A1/en active IP Right Grant
- 1999-12-29 AT AT99961232T patent/ATE290607T1/de not_active IP Right Cessation
- 1999-12-29 EP EP99961232A patent/EP1141392B1/de not_active Expired - Lifetime
- 1999-12-29 CA CA002358065A patent/CA2358065C/en not_active Expired - Fee Related
- 1999-12-29 JP JP2000592445A patent/JP3959438B2/ja not_active Expired - Fee Related
- 1999-12-29 AU AU17911/00A patent/AU771451B2/en not_active Ceased
-
2000
- 2000-01-25 TW TW088123389A patent/TWI235766B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JP2002534664A (ja) | 2002-10-15 |
US6294333B1 (en) | 2001-09-25 |
EP1141392B1 (de) | 2005-03-09 |
CA2358065A1 (en) | 2000-07-13 |
EP1141392A1 (de) | 2001-10-10 |
CA2358065C (en) | 2007-05-01 |
JP3959438B2 (ja) | 2007-08-15 |
WO2000040753A1 (en) | 2000-07-13 |
AU1791100A (en) | 2000-07-24 |
DE69924147D1 (de) | 2005-04-14 |
TWI235766B (en) | 2005-07-11 |
AU771451B2 (en) | 2004-03-25 |
DE69924147T2 (de) | 2006-01-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |