DE60239458D1 - Quinacridon markierungsreagenzien für fluoreszenz-nachweis von biologischen materialen - Google Patents
Quinacridon markierungsreagenzien für fluoreszenz-nachweis von biologischen materialenInfo
- Publication number
- DE60239458D1 DE60239458D1 DE60239458T DE60239458T DE60239458D1 DE 60239458 D1 DE60239458 D1 DE 60239458D1 DE 60239458 T DE60239458 T DE 60239458T DE 60239458 T DE60239458 T DE 60239458T DE 60239458 D1 DE60239458 D1 DE 60239458D1
- Authority
- DE
- Germany
- Prior art keywords
- sub
- sup
- group
- quinacridone
- nitro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B48/00—Quinacridones
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B15/00—Acridine dyes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/902—Oxidoreductases (1.)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0113434.5A GB0113434D0 (en) | 2001-06-04 | 2001-06-04 | Quinacridone derivatives as labels for fluorescence detection of biological materials |
PCT/GB2002/002537 WO2002099432A2 (en) | 2001-06-04 | 2002-05-30 | Quinacridone labelling reagents for fluorescence detection of biological materials |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60239458D1 true DE60239458D1 (de) | 2011-04-28 |
Family
ID=9915774
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60239458T Expired - Lifetime DE60239458D1 (de) | 2001-06-04 | 2002-05-30 | Quinacridon markierungsreagenzien für fluoreszenz-nachweis von biologischen materialen |
Country Status (9)
Country | Link |
---|---|
US (1) | US7335771B2 (de) |
EP (1) | EP1399742B1 (de) |
JP (1) | JP4317444B2 (de) |
AT (1) | ATE502301T1 (de) |
AU (1) | AU2002314302B2 (de) |
CA (1) | CA2449409C (de) |
DE (1) | DE60239458D1 (de) |
GB (2) | GB0113434D0 (de) |
WO (1) | WO2002099432A2 (de) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0208989D0 (en) | 2002-04-19 | 2002-05-29 | Amersham Biosciences Uk Ltd | Methods for measuring enzyme activity |
GB2398123B (en) * | 2002-04-19 | 2005-03-02 | Amersham Biosciences Uk Ltd | Methods for measuring enzyme activity |
GB0217562D0 (en) * | 2002-07-30 | 2002-09-11 | Amersham Biosciences Uk Ltd | Site-specific labelling of proteins using acridone and quinacridone lifetime dyes |
GB0317743D0 (en) | 2003-07-30 | 2003-09-03 | Amersham Biosciences Uk Ltd | Method for measuring aromatase activity |
EP1769048A1 (de) * | 2004-06-29 | 2007-04-04 | Ciba Specialty Chemicals Holding Inc. | Fluoreszierende chinacridone |
GB0421693D0 (en) | 2004-09-30 | 2004-11-03 | Amersham Biosciences Uk Ltd | Method for measuring binding of a test compound to a G-protein coupled receptor |
GB0505777D0 (en) * | 2005-03-22 | 2005-04-27 | Amersham Biosciences Uk Ltd | Enzyme detection method and reagent |
ATE423172T1 (de) * | 2005-11-28 | 2009-03-15 | Agfa Graphics Nv | Nichtwässerige chinakridondispersionen unter verwendung von dispersionssynergisten |
WO2007139724A1 (en) * | 2006-05-22 | 2007-12-06 | Sun Chemical Corporation | 2,5-di(methoxyanilino)terephthalic acid polymorphs and quinacridones realized therefrom |
US20100173332A1 (en) * | 2006-09-07 | 2010-07-08 | Auckland Uniservices Limited | Method for the Fluorescent Detection of Nitroreductase Activity Using Nitro-Substituted Aromatic Compounds |
EP2268656A1 (de) * | 2008-03-14 | 2011-01-05 | Assaymetrics Limited | Fluorogene peptide und verfahren zu ihrer herstellung |
EP2316890A1 (de) * | 2009-11-03 | 2011-05-04 | Agfa-Gevaert | Herstellung und Dispersion von oberflächenmodifizierten Farbpigmenten |
CA2746891A1 (en) * | 2010-07-19 | 2012-01-19 | Universite De Montreal | Fluorescent markers and use thereof for labelling specific protein targets |
ES2445940T1 (es) | 2011-03-25 | 2014-03-06 | Almac Sciences (Scotland) Limited | Ensayos enzimáticos |
CN102276600B (zh) * | 2011-04-22 | 2012-11-14 | 华东理工大学 | 喹吖啶酮衍生物及其用途 |
GB2511110A (en) * | 2013-02-25 | 2014-08-27 | Sudarshan Chemical Ind Ltd | Pigments |
EP3072975A4 (de) * | 2013-11-21 | 2017-05-03 | The University of Tokyo | Verfahren zur erkennung von fluoreszenz oder absorption, verfahren zur hintergrundunterdrückung, verfahren zur adp-messung, verfahren zur messung der aktivität eines adp-synthesierenden enzyms und verfahren zur messung der glucosyltransferaseaktivität |
US9701667B2 (en) | 2014-05-05 | 2017-07-11 | University Of Ottawa | Coumarin-based fluorogenic agents and uses thereof for specific protein labelling |
US10591485B2 (en) | 2015-01-23 | 2020-03-17 | University Of Ottawa | Peptide tags for fluorescent labelling of proteins |
JP2017020896A (ja) * | 2015-07-10 | 2017-01-26 | 国立大学法人北陸先端科学技術大学院大学 | N末端標識剤、これを用いた蛍光標識タンパク質及びその製造方法 |
US9958452B2 (en) | 2015-12-14 | 2018-05-01 | University Of Ottawa | Highly fluorogenic protein labelling agents |
EP3246969B1 (de) | 2016-05-17 | 2018-12-12 | Samsung SDI Co., Ltd. | Separator für eine wiederaufladbare batterie und wiederaufladbare lithiumbatterie damit |
JP7323539B2 (ja) | 2017-11-20 | 2023-08-08 | スティングセラ インコーポレイテッド | オキソアクリジニル酢酸誘導体および使用方法 |
US11414387B2 (en) | 2017-11-20 | 2022-08-16 | Stingthera, Inc. | Oxoacridinyl acetic acid derivatives and methods of use |
CN112794813B (zh) * | 2020-12-30 | 2022-04-26 | 四川大学华西医院 | 一种用于荧光标记的环丁烯衍生物 |
CN114605405B (zh) * | 2022-03-09 | 2023-09-05 | 吉林大学 | 一种基于喹吖啶酮骨架的细胞脂滴荧光成像探针及其应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61168666A (ja) * | 1985-01-21 | 1986-07-30 | Dainippon Ink & Chem Inc | 顔料組成物 |
DE59508671D1 (de) * | 1994-03-25 | 2000-10-05 | Ciba Sc Holding Ag | Cyaniminogruppen enthaltende Fluoreszenzfarbstoffe |
US5713999A (en) * | 1996-04-29 | 1998-02-03 | Bayer Corporation | Incorporation of pigment derivatives in quinacridone processes |
GB0208989D0 (en) * | 2002-04-19 | 2002-05-29 | Amersham Biosciences Uk Ltd | Methods for measuring enzyme activity |
-
2001
- 2001-06-04 GB GBGB0113434.5A patent/GB0113434D0/en not_active Ceased
-
2002
- 2002-05-30 JP JP2003502501A patent/JP4317444B2/ja not_active Expired - Fee Related
- 2002-05-30 AT AT02740872T patent/ATE502301T1/de not_active IP Right Cessation
- 2002-05-30 GB GB0326464A patent/GB2391550B/en not_active Expired - Fee Related
- 2002-05-30 AU AU2002314302A patent/AU2002314302B2/en not_active Ceased
- 2002-05-30 EP EP02740872A patent/EP1399742B1/de not_active Expired - Lifetime
- 2002-05-30 WO PCT/GB2002/002537 patent/WO2002099432A2/en active Application Filing
- 2002-05-30 DE DE60239458T patent/DE60239458D1/de not_active Expired - Lifetime
- 2002-05-30 CA CA2449409A patent/CA2449409C/en not_active Expired - Fee Related
- 2002-05-30 US US10/479,659 patent/US7335771B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
GB2391550B (en) | 2005-02-02 |
US20040171014A1 (en) | 2004-09-02 |
ATE502301T1 (de) | 2011-04-15 |
CA2449409A1 (en) | 2002-12-12 |
EP1399742A2 (de) | 2004-03-24 |
EP1399742B1 (de) | 2011-03-16 |
JP4317444B2 (ja) | 2009-08-19 |
GB0326464D0 (en) | 2003-12-17 |
JP2005501228A (ja) | 2005-01-13 |
US7335771B2 (en) | 2008-02-26 |
GB2391550A (en) | 2004-02-11 |
CA2449409C (en) | 2012-07-17 |
AU2002314302B2 (en) | 2006-02-23 |
WO2002099432A2 (en) | 2002-12-12 |
GB0113434D0 (en) | 2001-07-25 |
WO2002099432A3 (en) | 2003-05-01 |
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