ATE491699T1 - Verfahren zur herstellung von paclitaxel - Google Patents

Verfahren zur herstellung von paclitaxel

Info

Publication number
ATE491699T1
ATE491699T1 AT06709353T AT06709353T ATE491699T1 AT E491699 T1 ATE491699 T1 AT E491699T1 AT 06709353 T AT06709353 T AT 06709353T AT 06709353 T AT06709353 T AT 06709353T AT E491699 T1 ATE491699 T1 AT E491699T1
Authority
AT
Austria
Prior art keywords
radical
paclitaxel
oxazolidine
hydroxy
iii
Prior art date
Application number
AT06709353T
Other languages
English (en)
Inventor
Antoine Leze
Original Assignee
Seripharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seripharm filed Critical Seripharm
Application granted granted Critical
Publication of ATE491699T1 publication Critical patent/ATE491699T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT06709353T 2005-02-23 2006-02-21 Verfahren zur herstellung von paclitaxel ATE491699T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0501838A FR2882362B1 (fr) 2005-02-23 2005-02-23 Procede de preparation du paclitaxel
PCT/FR2006/000387 WO2006090057A1 (fr) 2005-02-23 2006-02-21 Procede de preparation du paclitaxel

Publications (1)

Publication Number Publication Date
ATE491699T1 true ATE491699T1 (de) 2011-01-15

Family

ID=35079381

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06709353T ATE491699T1 (de) 2005-02-23 2006-02-21 Verfahren zur herstellung von paclitaxel

Country Status (17)

Country Link
US (1) US7563914B2 (de)
EP (1) EP1856081B1 (de)
JP (1) JP2008531528A (de)
KR (1) KR20070108181A (de)
CN (1) CN101128448A (de)
AT (1) ATE491699T1 (de)
AU (1) AU2006217804A1 (de)
BR (1) BRPI0608015A2 (de)
CA (1) CA2597174A1 (de)
DE (1) DE602006018873D1 (de)
FR (1) FR2882362B1 (de)
IL (1) IL185278A0 (de)
MX (1) MX2007010271A (de)
NO (1) NO20074860L (de)
RU (1) RU2007134453A (de)
WO (1) WO2006090057A1 (de)
ZA (1) ZA200706798B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0618176D0 (en) * 2006-09-15 2006-10-25 Chatham Biotech Ltd One pot synthesis of taxane derivatives and their conversion to paclitaxel and docetaxel
GB0701523D0 (en) * 2007-01-26 2007-03-07 Chatham Biotec Ltd Semi-synthetic process for the preparation of taxane derivatives
CA2723654A1 (en) * 2008-05-07 2009-11-12 Ivax Research, Llc Processes for preparation of taxanes and intermediates thereof
KR101378537B1 (ko) * 2011-09-30 2014-03-28 주식회사 삼양바이오팜 10-디아세틸파클리탁셀로부터 파클리탁셀을 제조하는 방법
CN103130753B (zh) * 2013-03-14 2015-09-02 上海龙翔生物医药开发有限公司 抗肿瘤药物紫杉醇的半合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US622053A (en) * 1899-03-28 John w
FR2696459B1 (fr) * 1992-10-05 1994-11-25 Rhone Poulenc Rorer Sa Procédé de préparation de dérivés du taxane.
CA2170661A1 (en) * 1995-03-22 1996-09-23 John K. Thottathil Novel methods for the preparation of taxanes using oaxzolidine intermediates
CA2188190A1 (en) * 1996-10-18 1998-04-18 Sarala Balachandran The semi-synthesis of a protected bacatin iii compound
JP2002544269A (ja) * 1999-05-17 2002-12-24 ブリストル−マイヤーズ スクイブ カンパニー パクリタキセルおよびパクリタキセル類似体の製造におけるシリルエーテルの切断のための新規反応条件
US20050288520A1 (en) 2004-06-25 2005-12-29 Phytogen Life Sciences Inc. One pot synthesis of taxane derivatives and their conversion to paclitaxel and docetaxel

Also Published As

Publication number Publication date
WO2006090057A1 (fr) 2006-08-31
KR20070108181A (ko) 2007-11-08
BRPI0608015A2 (pt) 2009-11-03
EP1856081A1 (de) 2007-11-21
EP1856081B1 (de) 2010-12-15
CA2597174A1 (fr) 2006-08-31
DE602006018873D1 (de) 2011-01-27
US20080207929A1 (en) 2008-08-28
FR2882362A1 (fr) 2006-08-25
AU2006217804A1 (en) 2006-08-31
CN101128448A (zh) 2008-02-20
FR2882362B1 (fr) 2007-05-11
ZA200706798B (en) 2008-10-29
JP2008531528A (ja) 2008-08-14
US7563914B2 (en) 2009-07-21
RU2007134453A (ru) 2009-03-27
MX2007010271A (es) 2008-03-10
IL185278A0 (en) 2008-02-09
NO20074860L (no) 2007-11-20

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Legal Events

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