ATE48844T1 - Heterocyclische verbindungen, ihre herstellung und verwendung. - Google Patents

Heterocyclische verbindungen, ihre herstellung und verwendung.

Info

Publication number
ATE48844T1
ATE48844T1 AT86307542T AT86307542T ATE48844T1 AT E48844 T1 ATE48844 T1 AT E48844T1 AT 86307542 T AT86307542 T AT 86307542T AT 86307542 T AT86307542 T AT 86307542T AT E48844 T1 ATE48844 T1 AT E48844T1
Authority
AT
Austria
Prior art keywords
sub
production
heterocyclic compounds
alkyl
compounds
Prior art date
Application number
AT86307542T
Other languages
English (en)
Inventor
Frank Waetjen
Mogens Engelstoft
Original Assignee
Ferrosan As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrosan As filed Critical Ferrosan As
Application granted granted Critical
Publication of ATE48844T1 publication Critical patent/ATE48844T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Lubricants (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Cosmetics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AT86307542T 1985-10-17 1986-10-01 Heterocyclische verbindungen, ihre herstellung und verwendung. ATE48844T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK476885A DK476885D0 (da) 1985-10-17 1985-10-17 Heterocycliske forbindelser og fremgangsmaader til fremstilling heraf
EP86307542A EP0225013B1 (de) 1985-10-17 1986-10-01 Heterocyclische Verbindungen, ihre Herstellung und Verwendung

Publications (1)

Publication Number Publication Date
ATE48844T1 true ATE48844T1 (de) 1990-01-15

Family

ID=8136485

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86307542T ATE48844T1 (de) 1985-10-17 1986-10-01 Heterocyclische verbindungen, ihre herstellung und verwendung.

Country Status (18)

Country Link
US (5) US4870073A (de)
EP (2) EP0225013B1 (de)
JP (2) JPH0753731B2 (de)
KR (1) KR940010034B1 (de)
AT (1) ATE48844T1 (de)
AU (2) AU591937B2 (de)
CA (2) CA1275411C (de)
DE (1) DE3667665D1 (de)
DK (1) DK476885D0 (de)
ES (1) ES2014234B3 (de)
FI (2) FI864124A7 (de)
GR (1) GR3000367T3 (de)
IE (1) IE59642B1 (de)
IL (1) IL80319A (de)
NO (2) NO864061L (de)
NZ (2) NZ217957A (de)
PH (1) PH22556A (de)
PT (2) PT83571B (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK476885D0 (da) * 1985-10-17 1985-10-17 Ferrosan As Heterocycliske forbindelser og fremgangsmaader til fremstilling heraf
DE3686723T2 (de) * 1985-10-17 1993-04-01 Novonordisk As Oxadiazolylacetonitrile, ihre herstellung und anwendung.
DK174086D0 (da) * 1986-04-16 1986-04-16 Ferrosan As Nye benzodiazepinderivater samt fremgangsmaade til fremstilling af samme
DK155524C (da) * 1987-03-18 1989-09-11 Ferrosan As Kondenserede imidazolderivater og farmaceutiske praeparater indeholdende disse
DK160876C (da) * 1987-12-08 1991-10-14 Novo Nordisk As Imidazoquinoxalinforbindelser, fremgangsmaade til deres fremstilling, anvendelse af forbindelserne og farmaceutiske praeparater, hvori forbindelserne indgaar
IL90315A0 (en) * 1988-06-01 1989-12-15 Ferrosan As Imidazoquinoxaline compounds,their preparation and pharmaceutical compositions containing them
DK161148C (da) * 1988-06-14 1991-11-18 Novo Nordisk As Imidazoquinoxalinforbindelser, fremgangsmaade til fremstilling deraf samt farmaceutiske praeprater indeholdende forbindelserne
GB8823475D0 (en) * 1988-10-06 1988-11-16 Merck Sharp & Dohme Chemical compounds
DK626288D0 (da) * 1988-11-10 1988-11-10 Ferrosan As Kemisk proces til fremstilling af imidazoquinoxaliner og mellemprodukter til brug i processen
ATE105839T1 (de) * 1989-03-23 1994-06-15 Pfizer Antiallergische mittel auf der basis von diazepin.
DK443589D0 (da) * 1989-09-08 1989-09-08 Ferrosan As Heterocykliske forbindelser, deres fremstilling og anvendelse
DK588489D0 (da) * 1989-11-22 1989-11-22 Ferrosan As Heterocykliske forbindelser, deres fremstilling og anvendelse
DK588389D0 (da) * 1989-11-22 1989-11-22 Ferrosan As Heterocykliske forbindelser, deres fremstilling og anvendelse
US5276028A (en) * 1990-06-22 1994-01-04 Nordisk A/S Imidazoquinoxaline compounds
DK151890D0 (da) * 1990-06-22 1990-06-22 Ferrosan As Heterocykliske forbindelser deres fremstilling og brug
US5371080A (en) * 1990-06-22 1994-12-06 Novo Nordisk A/S Imidazoquinazoline compounds and their use
DK41191D0 (da) * 1991-03-07 1991-03-07 Novo Nordisk As Heterocycliske forbindelser, deres fremstilling og anvendelse
KR100207360B1 (ko) * 1991-06-14 1999-07-15 돈 더블유. 슈미츠 이미다조[1,5,-a]퀸옥살린
AU658441B2 (en) * 1991-07-23 1995-04-13 Schering Corporation Substituted beta-lactam compounds useful as hypocholesterolemic agents and processes for the preparation thereof
US5561227A (en) * 1991-07-23 1996-10-01 Schering Corporation Process for the stereospecific synthesis of azetidinones
AU4035893A (en) * 1991-12-17 1993-07-19 Upjohn Company, The 3-substituted imidazo (1,5-a) and imidazo (1,5-a)-triazolo (1,5-c) quinoxalines and quinazolines with cns activity
US5244906A (en) * 1992-01-23 1993-09-14 Dowelanco Insect control with substituted oxadiazole and thiadiazole compounds
AU3443593A (en) * 1992-02-13 1993-09-03 Upjohn Company, The 4-oxo- and 4H-imidazo(5,1-C)(1,4)benzoxazines useful as benzodiazepine receptor-binding agents
GB9212486D0 (en) * 1992-06-12 1992-07-22 Erba Carlo Spa Derivatives of substituted imidazo benzoxazin-1-one and process for their preparation
CA2143246C (en) * 1994-03-16 2000-08-22 Thierry Godel Imidazodiazepines
GB2328940B (en) * 1997-09-05 1999-12-08 Dong Kook Pharm Co Ltd A process for preparing benzodiazepine derivatives
EP1978966A4 (de) 2006-01-23 2010-11-10 Amira Pharmaceuticals Inc Tricyclische hemmer von 5-lipoxygenase
CN101827597B (zh) 2007-08-20 2013-03-13 伊沃泰克国际有限责任公司 睡眠障碍的治疗
US20090054412A1 (en) * 2007-08-20 2009-02-26 John Alan Kemp Treatment of Sleep Disorders
JO3156B1 (ar) 2009-07-09 2017-09-20 Novartis Ag ايميدازولات مدمجة والتركيبات التي تشملها لعلاج الأمراض الطفيلية على مثال الملاريا
KR102708936B1 (ko) 2015-11-20 2024-09-25 포르마 세라퓨틱스 인크. 유비퀴틴-특이적 프로테아제 1 억제제로서의 퓨리논
MX2019012758A (es) 2017-04-24 2019-12-16 Novartis Ag Regimen terapeutico de 2-amino-1-(2-(4-fluorofenil)-3-(4-fluorofen ilamino)-8,8-dimetil-5,6-dihidroimidazo [1,2-a]pirazin-7(8h)-il)et anona y combinaciones de la misma.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4118386A (en) * 1977-04-04 1978-10-03 Hoffmann-La Roche Inc. Synthesis of imidazo[1,5-a]diazepine-3-carboxylates
US4668678A (en) * 1980-05-09 1987-05-26 Usv Pharmaceutical Corporation Triazoloquinoxalin-1,4-diones
CA1184175A (en) * 1981-02-27 1985-03-19 Walter Hunkeler Imidazodiazepines
US4440929A (en) * 1981-07-16 1984-04-03 Usv Pharmaceutical Corporation Imidazoquinoxaline compounds
DK151808C (da) * 1982-11-16 1988-06-20 Ferrosan As Analogifremgangsmaade til fremstilling af oxadiazolylimidazo-oe1,4aa-benzodiazepinderivater
EP0150040B1 (de) * 1984-01-19 1994-08-31 F. Hoffmann-La Roche Ag Imidazodiazepin-Derivate
US4771051A (en) * 1985-05-17 1988-09-13 A/S Ferrosan 3-substituted-4,5-dihydro-5-oxo imidazoquinazolines, their preparation, and their use in treating benzodiazepin receptor-related ailments
DK476885D0 (da) * 1985-10-17 1985-10-17 Ferrosan As Heterocycliske forbindelser og fremgangsmaader til fremstilling heraf
DE3686723T2 (de) * 1985-10-17 1993-04-01 Novonordisk As Oxadiazolylacetonitrile, ihre herstellung und anwendung.
FR2598147B1 (fr) * 1986-04-30 1988-08-26 Pasteur Institut Immunogene isole de mollusques, son procede de preparation, reactifs de diagnostic des bilharzioses humaines, vaccins contre les schistosomiases et compositions immunisantes comprenant ledit immunogene.

Also Published As

Publication number Publication date
IE862733L (en) 1987-04-17
JPH0753731B2 (ja) 1995-06-07
CA1293723C (en) 1991-12-31
EP0225013A1 (de) 1987-06-10
NO163776C (no) 1990-07-18
PH22556A (en) 1988-10-17
FI864125A0 (fi) 1986-10-13
NO163776B (no) 1990-04-09
NZ217958A (en) 1989-02-24
FI864125A7 (fi) 1987-04-18
NO864061L (no) 1987-04-21
IE59642B1 (en) 1994-03-09
EP0220845A1 (de) 1987-05-06
CA1275411C (en) 1990-10-23
AU6417986A (en) 1987-04-30
US4886797A (en) 1989-12-12
AU591937B2 (en) 1989-12-21
US4774245A (en) 1988-09-27
US4880799A (en) 1989-11-14
JPS62155278A (ja) 1987-07-10
FI82050C (fi) 1991-01-10
KR940010034B1 (ko) 1994-10-21
GR3000367T3 (en) 1991-06-07
FI82050B (fi) 1990-09-28
US4870073A (en) 1989-09-26
FI864124A7 (fi) 1987-04-18
PT83571A (en) 1986-11-01
AU6417886A (en) 1987-04-30
PT83572A (en) 1986-11-01
NZ217957A (en) 1989-02-24
NO864062D0 (no) 1986-10-13
NO864062L (no) 1987-04-21
JPS62161785A (ja) 1987-07-17
IL80319A (en) 1990-03-19
US4795749A (en) 1989-01-03
DE3667665D1 (de) 1990-01-25
KR870004032A (ko) 1987-05-07
DK476885D0 (da) 1985-10-17
FI864124A0 (fi) 1986-10-13
NO864061D0 (no) 1986-10-13
PT83571B (en) 1988-03-09
PT83572B (pt) 1988-10-14
ES2014234B3 (es) 1990-07-01
EP0225013B1 (de) 1989-12-20

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner
REN Ceased due to non-payment of the annual fee