DK626288D0 - Kemisk proces til fremstilling af imidazoquinoxaliner og mellemprodukter til brug i processen - Google Patents
Kemisk proces til fremstilling af imidazoquinoxaliner og mellemprodukter til brug i processenInfo
- Publication number
- DK626288D0 DK626288D0 DK626288A DK626288A DK626288D0 DK 626288 D0 DK626288 D0 DK 626288D0 DK 626288 A DK626288 A DK 626288A DK 626288 A DK626288 A DK 626288A DK 626288 D0 DK626288 D0 DK 626288D0
- Authority
- DK
- Denmark
- Prior art keywords
- imidazoquinoxalines
- intermediates
- preparation
- chemical process
- chemical
- Prior art date
Links
- 238000001311 chemical methods and process Methods 0.000 title abstract 2
- 239000000543 intermediate Substances 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- -1 -tert-butyl compound Chemical class 0.000 abstract 1
- YELMWJNXDALKFE-UHFFFAOYSA-N 3h-imidazo[4,5-f]quinoxaline Chemical group N1=CC=NC2=C(NC=N3)C3=CC=C21 YELMWJNXDALKFE-UHFFFAOYSA-N 0.000 abstract 1
- 230000020335 dealkylation Effects 0.000 abstract 1
- 238000006900 dealkylation reaction Methods 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Priority Applications (19)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK626288A DK626288D0 (da) | 1988-11-10 | 1988-11-10 | Kemisk proces til fremstilling af imidazoquinoxaliner og mellemprodukter til brug i processen |
| IL9205589A IL92055A (en) | 1988-11-10 | 1989-10-19 | 3-(cycloalkyl substituted 1,2,4-oxadiazolyl)-4,5-dihydro-4-oxo-5- tertbutyl-imidaz (1,5-a) quinoxalines |
| IE337489A IE68939B1 (en) | 1988-11-10 | 1989-10-20 | Imidazoquinoxalines and their preparation |
| ZA898051A ZA898051B (en) | 1988-11-10 | 1989-10-24 | Chemical process for the preparation of imidazoquinoxalines and intermediates for use in the process |
| AU44393/89A AU622941B2 (en) | 1988-11-10 | 1989-11-03 | Chemical process for the preparation of imidazoquinoxalines and intermediates for use in the process |
| FI895257A FI92931C (fi) | 1988-11-10 | 1989-11-06 | Menetelmä uusien terapeuttisesti aktiivisten 4-okso-5-tert.butyyli-imidatso/1,5-a/kinoksaliinien valmistamiseksi |
| JP1288081A JPH02178285A (ja) | 1988-11-10 | 1989-11-07 | イミダゾキノキサリンの化学的製造方法および該方法に使用する中間体 |
| DK556289A DK163511C (da) | 1988-11-10 | 1989-11-08 | Imidazooe1,5-aaaquinoxalinforbindelser og farmaceutiske praeparater indeholdende disse |
| US07/433,668 US4999353A (en) | 1988-11-10 | 1989-11-08 | Chemical process for the preparation of imidazo-quinoxalines and intermediates for use in the process |
| NZ23975889A NZ239758A (en) | 1988-11-10 | 1989-11-08 | Oxadiazole-substituted imidazo (1,5-a) quinoxaline derivatives and pharmaceutical compositions |
| NZ231321A NZ231321A (en) | 1988-11-10 | 1989-11-08 | Substituted imidazo-(1,5-a)quinoxaline derivatives and their preparation |
| DE68921418T DE68921418T2 (de) | 1988-11-10 | 1989-11-09 | Imidazochinoxaline und ihre Herstellung. |
| EP89311587A EP0368652B1 (en) | 1988-11-10 | 1989-11-09 | Imidazoquinoxalines and their preparation |
| AT89311587T ATE119162T1 (de) | 1988-11-10 | 1989-11-09 | Imidazochinoxaline und ihre herstellung. |
| CA002002624A CA2002624A1 (en) | 1988-11-10 | 1989-11-09 | Chemical process for the preparation of imidazoquinoxalines and intermediates for use in the process |
| NO894474A NO173827C (no) | 1988-11-10 | 1989-11-09 | Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazokinoxaliner |
| ES89311587T ES2068903T3 (es) | 1988-11-10 | 1989-11-09 | Imidazoquinoxalinas y su preparacion. |
| PT92279A PT92279B (pt) | 1988-11-10 | 1989-11-10 | Processo de preparacao de imidazoquinoxalinas |
| GR950400849T GR3015718T3 (en) | 1988-11-10 | 1995-04-10 | Imidazoquinoxalines and their preparation. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK626288A DK626288D0 (da) | 1988-11-10 | 1988-11-10 | Kemisk proces til fremstilling af imidazoquinoxaliner og mellemprodukter til brug i processen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK626288D0 true DK626288D0 (da) | 1988-11-10 |
Family
ID=8148369
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK626288A DK626288D0 (da) | 1988-11-10 | 1988-11-10 | Kemisk proces til fremstilling af imidazoquinoxaliner og mellemprodukter til brug i processen |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4999353A (da) |
| EP (1) | EP0368652B1 (da) |
| JP (1) | JPH02178285A (da) |
| AT (1) | ATE119162T1 (da) |
| AU (1) | AU622941B2 (da) |
| CA (1) | CA2002624A1 (da) |
| DE (1) | DE68921418T2 (da) |
| DK (1) | DK626288D0 (da) |
| ES (1) | ES2068903T3 (da) |
| FI (1) | FI92931C (da) |
| GR (1) | GR3015718T3 (da) |
| IE (1) | IE68939B1 (da) |
| IL (1) | IL92055A (da) |
| NO (1) | NO173827C (da) |
| NZ (1) | NZ231321A (da) |
| PT (1) | PT92279B (da) |
| ZA (1) | ZA898051B (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK588489D0 (da) * | 1989-11-22 | 1989-11-22 | Ferrosan As | Heterocykliske forbindelser, deres fremstilling og anvendelse |
| CA2110942A1 (en) * | 1991-06-14 | 1992-12-23 | Pharmacia & Upjohn Company Llc | Imidazo¬1,5-a|quinoxalines |
| WO1993012113A1 (en) * | 1991-12-17 | 1993-06-24 | The Upjohn Company | 3-SUBSTITUTED IMIDAZO (1,5-a) AND IMIDAZO (1,5-a)-TRIAZOLO (1,5-c) QUINOXALINES AND QUINAZOLINES WITH CNS ACTIVITY |
| DE4228095A1 (de) * | 1992-08-24 | 1994-03-03 | Asta Medica Ag | Neue 4,5-Dihydro-4-oxo-pyrrolo[1,2-a]chinoxaline und entsprechende Aza-analoga und Verfahren zu deren Herstellung |
| FR2696466B1 (fr) * | 1992-10-02 | 1994-11-25 | Rhone Poulenc Rorer Sa | Dérivés de 5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one, leur préparation et les médicaments les contenant. |
| US5792766A (en) * | 1996-03-13 | 1998-08-11 | Neurogen Corporation | Imidazo 1,5-c! quinazolines; a new class of GABA brain receptor ligands |
| JP4042925B2 (ja) * | 1996-11-20 | 2008-02-06 | シスメックス株式会社 | 幼若白血球の分類計数法 |
| US20040180898A1 (en) * | 2003-03-03 | 2004-09-16 | Bang-Chi Chen | Processes for preparing imidazoquinoxalinones, heterocyclic-substituted imidazopyrazinones, imidazoquinoxalines and heterocyclic-substituted imidazopyrazines |
| RU2750151C2 (ru) | 2015-11-20 | 2021-06-22 | Форма Терапьютикс, Инк. | Гипоксантины в качестве ингибиторов убиквитин-специфической протеазы 1 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4440929A (en) * | 1981-07-16 | 1984-04-03 | Usv Pharmaceutical Corporation | Imidazoquinoxaline compounds |
| DK476885D0 (da) * | 1985-10-17 | 1985-10-17 | Ferrosan As | Heterocycliske forbindelser og fremgangsmaader til fremstilling heraf |
| DE3686723T2 (de) * | 1985-10-17 | 1993-04-01 | Novonordisk As | Oxadiazolylacetonitrile, ihre herstellung und anwendung. |
| DK155524C (da) * | 1987-03-18 | 1989-09-11 | Ferrosan As | Kondenserede imidazolderivater og farmaceutiske praeparater indeholdende disse |
| DK160876C (da) * | 1987-12-08 | 1991-10-14 | Novo Nordisk As | Imidazoquinoxalinforbindelser, fremgangsmaade til deres fremstilling, anvendelse af forbindelserne og farmaceutiske praeparater, hvori forbindelserne indgaar |
| IL90315A0 (en) * | 1988-06-01 | 1989-12-15 | Ferrosan As | Imidazoquinoxaline compounds,their preparation and pharmaceutical compositions containing them |
-
1988
- 1988-11-10 DK DK626288A patent/DK626288D0/da not_active Application Discontinuation
-
1989
- 1989-10-19 IL IL9205589A patent/IL92055A/en not_active IP Right Cessation
- 1989-10-20 IE IE337489A patent/IE68939B1/en not_active IP Right Cessation
- 1989-10-24 ZA ZA898051A patent/ZA898051B/xx unknown
- 1989-11-03 AU AU44393/89A patent/AU622941B2/en not_active Ceased
- 1989-11-06 FI FI895257A patent/FI92931C/fi not_active IP Right Cessation
- 1989-11-07 JP JP1288081A patent/JPH02178285A/ja active Pending
- 1989-11-08 US US07/433,668 patent/US4999353A/en not_active Expired - Fee Related
- 1989-11-08 NZ NZ231321A patent/NZ231321A/xx unknown
- 1989-11-09 ES ES89311587T patent/ES2068903T3/es not_active Expired - Lifetime
- 1989-11-09 EP EP89311587A patent/EP0368652B1/en not_active Expired - Lifetime
- 1989-11-09 DE DE68921418T patent/DE68921418T2/de not_active Expired - Fee Related
- 1989-11-09 CA CA002002624A patent/CA2002624A1/en not_active Abandoned
- 1989-11-09 AT AT89311587T patent/ATE119162T1/de not_active IP Right Cessation
- 1989-11-09 NO NO894474A patent/NO173827C/no unknown
- 1989-11-10 PT PT92279A patent/PT92279B/pt not_active IP Right Cessation
-
1995
- 1995-04-10 GR GR950400849T patent/GR3015718T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU4439389A (en) | 1990-05-17 |
| FI92931B (fi) | 1994-10-14 |
| FI92931C (fi) | 1995-01-25 |
| ES2068903T3 (es) | 1995-05-01 |
| NO173827C (no) | 1994-02-09 |
| ATE119162T1 (de) | 1995-03-15 |
| FI895257A0 (fi) | 1989-11-06 |
| IL92055A0 (en) | 1990-07-12 |
| NO894474L (no) | 1990-05-11 |
| EP0368652A1 (en) | 1990-05-16 |
| IE68939B1 (en) | 1996-07-24 |
| GR3015718T3 (en) | 1995-07-31 |
| US4999353A (en) | 1991-03-12 |
| NO894474D0 (no) | 1989-11-09 |
| JPH02178285A (ja) | 1990-07-11 |
| CA2002624A1 (en) | 1990-05-10 |
| DE68921418T2 (de) | 1995-07-13 |
| PT92279B (pt) | 1995-08-09 |
| EP0368652B1 (en) | 1995-03-01 |
| IE893374L (en) | 1990-05-10 |
| NZ231321A (en) | 1991-10-25 |
| PT92279A (pt) | 1990-05-31 |
| ZA898051B (en) | 1990-08-29 |
| NO173827B (no) | 1993-11-01 |
| IL92055A (en) | 1994-01-25 |
| AU622941B2 (en) | 1992-04-30 |
| DE68921418D1 (de) | 1995-04-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHS | Application shelved for other reasons than non-payment |