ATE481989T1 - Material zum tragen eines medizinischen implantats - Google Patents

Material zum tragen eines medizinischen implantats

Info

Publication number
ATE481989T1
ATE481989T1 AT07252847T AT07252847T ATE481989T1 AT E481989 T1 ATE481989 T1 AT E481989T1 AT 07252847 T AT07252847 T AT 07252847T AT 07252847 T AT07252847 T AT 07252847T AT E481989 T1 ATE481989 T1 AT E481989T1
Authority
AT
Austria
Prior art keywords
medical implant
supporting
polymer backbone
uhmwpe
pendant
Prior art date
Application number
AT07252847T
Other languages
English (en)
Inventor
Richard S King
Craig Ernsberger
Original Assignee
Depuy Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Depuy Products Inc filed Critical Depuy Products Inc
Application granted granted Critical
Publication of ATE481989T1 publication Critical patent/ATE481989T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/34Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/16Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L23/00Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
    • C08L23/02Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers not modified by chemical after-treatment
    • C08L23/04Homopolymers or copolymers of ethene
    • C08L23/06Polyethylene
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/32Joints for the hip
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L23/00Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
    • C08L23/02Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers not modified by chemical after-treatment
    • C08L23/04Homopolymers or copolymers of ethene
    • C08L23/08Copolymers of ethene
    • C08L23/0846Copolymers of ethene with unsaturated hydrocarbons containing atoms other than carbon or hydrogen
    • C08L23/0869Copolymers of ethene with unsaturated hydrocarbons containing atoms other than carbon or hydrogen with unsaturated acids, e.g. [meth]acrylic acid; with unsaturated esters, e.g. [meth]acrylic acid esters
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L23/00Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
    • C08L23/02Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers not modified by chemical after-treatment
    • C08L23/04Homopolymers or copolymers of ethene
    • C08L23/08Copolymers of ethene
    • C08L23/0846Copolymers of ethene with unsaturated hydrocarbons containing atoms other than carbon or hydrogen
    • C08L23/0869Copolymers of ethene with unsaturated hydrocarbons containing atoms other than carbon or hydrogen with unsaturated acids, e.g. [meth]acrylic acid; with unsaturated esters, e.g. [meth]acrylic acid esters
    • C08L23/0884Epoxide-containing esters
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2312/00Crosslinking
    • C08L2312/06Crosslinking by radiation
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L51/00Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
    • C08L51/06Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers grafted on to homopolymers or copolymers of aliphatic hydrocarbons containing only one carbon-to-carbon double bond
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L53/00Compositions of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02Polyalkylene oxides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
AT07252847T 2006-08-25 2007-07-18 Material zum tragen eines medizinischen implantats ATE481989T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US84024106P 2006-08-25 2006-08-25

Publications (1)

Publication Number Publication Date
ATE481989T1 true ATE481989T1 (de) 2010-10-15

Family

ID=38800793

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07252847T ATE481989T1 (de) 2006-08-25 2007-07-18 Material zum tragen eines medizinischen implantats

Country Status (10)

Country Link
US (2) US7683133B2 (de)
EP (1) EP1891987B1 (de)
JP (1) JP5143501B2 (de)
CN (1) CN101130109A (de)
AT (1) ATE481989T1 (de)
AU (1) AU2007211885B2 (de)
DE (1) DE602007009345D1 (de)
DK (1) DK1891987T3 (de)
ES (1) ES2350708T3 (de)
ZA (1) ZA200707186B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8524884B2 (en) 2001-10-30 2013-09-03 Colorado State University Research Foundation Outer layer material having entanglement of hydrophobic polymer hostblended with a maleated hydrophobic polymer co-host, and hydrophilic polymer guest
US7662954B2 (en) 2001-10-30 2010-02-16 Colorado State University Research Foundation Outer layer having entanglement of hydrophobic polymer host and hydrophilic polymer guest
ATE449618T1 (de) * 2005-08-18 2009-12-15 Zimmer Gmbh Ultrahochmolekulare polyethylen-artikel und verfahren zur herstellung von ultrahochmolekularen polyethylen-artikeln
DE602007009345D1 (de) * 2006-08-25 2010-11-04 Depuy Products Inc Material zum Tragen eines medizinischen Implantats
EP2578248B1 (de) 2007-04-10 2021-05-19 Zimmer, Inc. Antioxidans-stabilisiertes, vernetztes Polyethylen mit ultrahohem Molekulargewicht für Medizingeräteanwendungen
US8664290B2 (en) * 2007-04-10 2014-03-04 Zimmer, Inc. Antioxidant stabilized crosslinked ultra-high molecular weight polyethylene for medical device applications
US8652212B2 (en) * 2008-01-30 2014-02-18 Zimmer, Inc. Orthopedic component of low stiffness
RU2010141763A (ru) * 2008-03-12 2012-04-20 Нонлайнеар Текнолоджиз Лтд. (Il) Спинальный имплантат с опорой конструкции и поверхностями раздела кости, образованными из увммпэ
JP4806717B2 (ja) * 2009-06-25 2011-11-02 株式会社沖データ 画像処理システム
GB0922339D0 (en) 2009-12-21 2010-02-03 Mcminn Derek J W Acetabular cup prothesis and introducer thereof
US20140024736A1 (en) * 2010-11-03 2014-01-23 Zimmer, Inc. Polymer articles having chemically bonded agents and methods of making the same
CN102526802B (zh) * 2012-01-06 2013-10-30 中国矿业大学 一种仿生软骨材料与硬面基底结合的仿生材料的制备工艺
EP3052562B1 (de) 2013-10-01 2017-11-08 Zimmer, Inc. Polymerzusammensetzungen, enthaltend ein oder mehrere geschützte antioxidantien
US10184031B2 (en) 2014-03-12 2019-01-22 Zimmer, Inc. Melt-stabilized ultra high molecular weight polyethylene and method of making the same
EP3227360B1 (de) 2014-12-03 2024-10-16 Zimmer, Inc. Mit antioxidationsmittel infundiertes polyethylen mit ultrahohem molekulargewicht
JP2019146747A (ja) * 2018-02-27 2019-09-05 賀代 小久保 歯科用インプラントの埋入方法

Family Cites Families (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE601705A (de) 1960-03-23
JPS5018909B2 (de) 1971-11-09 1975-07-02
US3954927A (en) 1973-02-05 1976-05-04 Sun Ventures, Inc. Method of making porous objects of ultra high molecular weight polyethylene
US4454612A (en) 1980-05-07 1984-06-19 Biomet, Inc. Prosthesis formation having solid and porous polymeric components
CA1142883A (en) 1980-09-04 1983-03-15 George White Process for irradiation of polyethylene
JPS60252645A (ja) 1984-05-30 1985-12-13 Sekisui Chem Co Ltd 超高分子量ポリエチレン組成物
DE3582435D1 (de) 1984-01-06 1991-05-16 Mitsui Petrochemical Ind Thermoplastische harzzusammensetzungen.
WO1985004365A1 (en) 1984-03-29 1985-10-10 American Hoechst Corporation Polyethylene molding composition and process
US4778601A (en) 1984-10-09 1988-10-18 Millipore Corporation Microporous membranes of ultrahigh molecular weight polyethylene
DD227328A1 (de) 1984-10-10 1985-09-18 Adw Ddr Faserverstaerktes implantat aus ultrahochmolekularem polyethylen
AU5017285A (en) 1984-10-24 1986-05-15 Zachariades, A.E. Ultra-high-molecular-weight polyethylene products including vascular prosthesis devices and methods relating thereto and employing pseudo-gel states
US4880843A (en) 1988-03-28 1989-11-14 Hoechst Celanese Corporation Composition and process for making porous articles from ultra high molecular weight polyethylene
US5275838A (en) 1990-02-28 1994-01-04 Massachusetts Institute Of Technology Immobilized polyethylene oxide star molecules for bioapplications
JP2957021B2 (ja) 1991-01-25 1999-10-04 テルモ株式会社 医療用材料および医療用器具ならびに医療用材料の製造方法
US5288818A (en) 1991-08-20 1994-02-22 Exxon Chemical Patents Inc. Method for separating a water soluble noble metal catalyst from a noble metal catalyzed hydroformylation reaction
US5414049A (en) 1993-06-01 1995-05-09 Howmedica Inc. Non-oxidizing polymeric medical implant
US5593719A (en) 1994-03-29 1997-01-14 Southwest Research Institute Treatments to reduce frictional wear between components made of ultra-high molecular weight polyethylene and metal alloys
ES2138699T3 (es) * 1994-04-11 2000-01-16 Bristol Myers Squibb Co Implante de material compuesto polimerico y procedimiento de fabricacion.
CA2166450C (en) 1995-01-20 2008-03-25 Ronald Salovey Chemically crosslinked ultrahigh molecular weight polyethylene for artificial human joints
US5594055A (en) 1995-02-22 1997-01-14 Hoffmann-La Roche Inc. Antioxidant system for polyolefins
US5879400A (en) 1996-02-13 1999-03-09 Massachusetts Institute Of Technology Melt-irradiated ultra high molecular weight polyethylene prosthetic devices
US5721334A (en) 1996-02-16 1998-02-24 Newyork Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery Process for producing ultra-high molecular weight low modulus polyethylene shaped articles via controlled pressure and temperature and compositions and articles produced therefrom
US5844027A (en) 1996-05-03 1998-12-01 Ciba Specialty Chemicals Corporation Stabilizer composition for thermoplastic materials
US6228900B1 (en) 1996-07-09 2001-05-08 The Orthopaedic Hospital And University Of Southern California Crosslinking of polyethylene for low wear using radiation and thermal treatments
DE69737325T2 (de) 1996-07-09 2007-11-22 University Of Southern California, Los Angeles Vernetzung von polyethylen zur verringerung der abnutzung unter anwendung von strahlung und thermischer behandlung
US5827904A (en) 1996-09-27 1998-10-27 Hahn; David Medical implant composition
US6017975A (en) 1996-10-02 2000-01-25 Saum; Kenneth Ashley Process for medical implant of cross-linked ultrahigh molecular weight polyethylene having improved balance of wear properties and oxidation resistance
AU4986497A (en) 1996-10-15 1998-05-11 Orthopaedic Hospital, The Wear resistant surface-gradient cross-linked polyethylene
US5945457A (en) * 1997-10-01 1999-08-31 A.V. Topchiev Institute Of Petrochemical Synthesis, Russian Academy Of Science Process for preparing biologically compatible polymers and their use in medical devices
EP0995449A1 (de) 1998-10-21 2000-04-26 Sulzer Orthopädie AG UHMW-Polyethylen für Implantate
AU1926100A (en) 1998-11-30 2000-06-19 Regents Of The University Of California, The Plasma-assisted surface modification of polymers for medical device applications
SE9900519D0 (sv) 1999-02-17 1999-02-17 Lars Lidgren A method for the preparation of UHMWPE doped with an antioxidant and an implant made thereof
US6365089B1 (en) 1999-09-24 2002-04-02 Zimmer, Inc. Method for crosslinking UHMWPE in an orthopaedic implant
US6395799B1 (en) 2000-02-21 2002-05-28 Smith & Nephew, Inc. Electromagnetic and mechanical wave energy treatments of UHMWPE
ATE418933T1 (de) 2000-04-27 2009-01-15 Orthopaedic Hospital Oxidationsbeständige und abriebfeste polyethylene fur menschlichen gelenkersatz und verfahren zu deren herstellung
EP1330347B1 (de) 2000-09-29 2006-08-16 Depuy Orthopaedics, Inc. Behandlung eines bestrahlten vorformlings eines prothetischen lagerelementes aus polyethylen mit einem überkritischen fluid
US6818172B2 (en) 2000-09-29 2004-11-16 Depuy Products, Inc. Oriented, cross-linked UHMWPE molding for orthopaedic applications
US7662954B2 (en) 2001-10-30 2010-02-16 Colorado State University Research Foundation Outer layer having entanglement of hydrophobic polymer host and hydrophilic polymer guest
AU2002364530B2 (en) 2001-12-12 2008-09-25 Depuy Products, Inc. Orthopaedic device and method for making same
US6743388B2 (en) 2001-12-31 2004-06-01 Advanced Cardiovascular Systems, Inc. Process of making polymer articles
EP1463457A4 (de) 2002-01-04 2006-12-20 Massachusetts Gen Hospital Vernetztes polyethylen mit hohem spannungswert, mit reduzierter restradikalkonzentration; hergestellt unter dem schmelzpunkt
US7186364B2 (en) 2002-01-28 2007-03-06 Depuy Products, Inc. Composite prosthetic bearing constructed of polyethylene and an ethylene-acrylate copolymer and method for making the same
US7819925B2 (en) * 2002-01-28 2010-10-26 Depuy Products, Inc. Composite prosthetic bearing having a crosslinked articulating surface and method for making the same
US7785372B2 (en) 2002-02-19 2010-08-31 Kabushiki Kaisha Kobe Seiko Sho Artificial joint member with grafted polymer surface
US7238744B2 (en) 2002-04-12 2007-07-03 Daramic, Inc. Ultrahigh molecular weight polyethylene articles and method of manufacture
US20050019366A1 (en) 2002-12-31 2005-01-27 Zeldis Jerome B. Drug-coated stents and methods of use therefor
WO2004064618A2 (en) 2003-01-16 2004-08-05 Massachusetts General Hospital Methods for making oxidation resistant polymeric material
US7938861B2 (en) 2003-04-15 2011-05-10 Depuy Products, Inc. Implantable orthopaedic device and method for making the same
US20040265165A1 (en) 2003-06-30 2004-12-30 Depuy Products, Inc. Free radical quench process for irradiated ultrahigh molecular weight polyethylene
US7214764B2 (en) 2003-06-30 2007-05-08 Depuy Products, Inc. Free radical quench process for irradiated ultrahigh molecular weight polyethylene
US20040262809A1 (en) 2003-06-30 2004-12-30 Smith Todd S. Crosslinked polymeric composite for orthopaedic implants
US20050065307A1 (en) * 2003-09-19 2005-03-24 Depuy Products, Inc. Medical implant or medical implant part comprising porous UHMWPE and process for producing the same
US7205051B2 (en) 2003-09-30 2007-04-17 Depuy Products, Inc. Medical implant or medical implant part
US7384430B2 (en) 2004-06-30 2008-06-10 Depuy Products, Inc. Low crystalline polymeric material for orthopaedic implants and an associated method
US7896921B2 (en) 2004-12-30 2011-03-01 Depuy Products, Inc. Orthopaedic bearing and method for making the same
US7879275B2 (en) 2004-12-30 2011-02-01 Depuy Products, Inc. Orthopaedic bearing and method for making the same
US8343230B2 (en) 2005-09-22 2013-01-01 Depuy Products, Inc. Orthopaedic bearing material
DE602007009345D1 (de) * 2006-08-25 2010-11-04 Depuy Products Inc Material zum Tragen eines medizinischen Implantats

Also Published As

Publication number Publication date
AU2007211885B2 (en) 2012-09-20
JP2008114045A (ja) 2008-05-22
EP1891987A3 (de) 2008-04-02
EP1891987A2 (de) 2008-02-27
ES2350708T3 (es) 2011-01-26
ZA200707186B (en) 2009-09-30
US20100137522A1 (en) 2010-06-03
DK1891987T3 (da) 2010-12-13
DE602007009345D1 (de) 2010-11-04
JP5143501B2 (ja) 2013-02-13
EP1891987B1 (de) 2010-09-22
US20080071026A1 (en) 2008-03-20
CN101130109A (zh) 2008-02-27
AU2007211885A1 (en) 2008-03-13
US7683133B2 (en) 2010-03-23

Similar Documents

Publication Publication Date Title
ATE481989T1 (de) Material zum tragen eines medizinischen implantats
WO2007148230A3 (en) Grafted polymers and uses thereof
TW200631604A (en) Ophthalmic compositions comprising polyether substituted polymers
ATE489058T1 (de) Bandscheiben-nucleus-pulposus-implantat
WO2012021812A3 (en) Patellar implants
WO2008039655A3 (en) Pendant end-capped low modulus cationic siloxanyls
WO2005069966A3 (en) Vascular grafts with amphiphilic block copolymer coatings
WO2007103772A3 (en) Catheter shaft with a lubricious surface
EP2309990A4 (de) Mit wirkstoff beladene polymernanopartikel sowie verfahren zu ihrer herstellung und verwendung
ATE369093T1 (de) Herstellungsverfahren eines komposit- prothesenlagerelements mit einer vernetzten gelenkfläche
DE502007007080D1 (de) Knieprothese
ATE506392T1 (de) Blockcopolymer für wirkstoffkonjugate und deren pharmazeutische zusammensetzungen
ATE540706T1 (de) Methacrylat-copolymere für medizinprodukte
DE60119906D1 (de) Zusammensetzungen zur erhöhung des gewebevolumens und beschichtungszusammensetzungen
ATE479421T1 (de) Kationisches konditionierungsmittel
BRPI0519418A2 (pt) copolÍmero de hidrogel, e, lente de contato
TW200745220A (en) Copolymers comprising polyamide blocks and polyethers blocks having improved optical and/or mechanical properties
NO20083573L (no) Amfifile polymerer for opploseliggjoring og malrettet avgivelse av legemidler
ATE467650T1 (de) Biologisch aktive blockcopolymere und damit beschichtete artikel
ATE501743T1 (de) Material zum tragen eines medizinischen implantats
DK1779877T3 (da) Bæremateriale for medicinske implantater
Marmo et al. Biomedical silicones: leveraging additive strategies to propel modern utility
ATE483777T1 (de) Amphiphile blockcopolymere und deren verwendung
ATE527002T1 (de) Trägermaterial für ein medizinisches implantat
ATE526040T1 (de) Drug delivery systeme

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1891987

Country of ref document: EP