ZA200707186B - Bearing material of medical implant and method for making it - Google Patents
Bearing material of medical implant and method for making it Download PDFInfo
- Publication number
- ZA200707186B ZA200707186B ZA200707186A ZA200707186A ZA200707186B ZA 200707186 B ZA200707186 B ZA 200707186B ZA 200707186 A ZA200707186 A ZA 200707186A ZA 200707186 A ZA200707186 A ZA 200707186A ZA 200707186 B ZA200707186 B ZA 200707186B
- Authority
- ZA
- South Africa
- Prior art keywords
- bearing material
- uhmwpe
- pendant
- polyethylene
- polymer backbone
- Prior art date
Links
- 239000000463 material Substances 0.000 title claims abstract description 106
- 239000007943 implant Substances 0.000 title claims abstract description 40
- 238000000034 method Methods 0.000 title claims description 52
- -1 polyethylene copolymer Polymers 0.000 claims abstract description 61
- 239000004698 Polyethylene Substances 0.000 claims abstract description 58
- 229920000573 polyethylene Polymers 0.000 claims abstract description 58
- 229920000785 ultra high molecular weight polyethylene Polymers 0.000 claims abstract description 52
- 239000004699 Ultra-high molecular weight polyethylene Substances 0.000 claims abstract description 50
- 229920000642 polymer Polymers 0.000 claims abstract description 47
- 239000004094 surface-active agent Substances 0.000 claims abstract description 30
- 229920010741 Ultra High Molecular Weight Polyethylene (UHMWPE) Polymers 0.000 claims abstract description 23
- 239000002131 composite material Substances 0.000 claims abstract description 21
- 230000008569 process Effects 0.000 claims description 43
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 26
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 21
- 229920001400 block copolymer Polymers 0.000 claims description 18
- 238000000748 compression moulding Methods 0.000 claims description 18
- 229920005862 polyol Polymers 0.000 claims description 17
- 150000003077 polyols Chemical class 0.000 claims description 17
- 238000003754 machining Methods 0.000 claims description 15
- 230000006835 compression Effects 0.000 claims description 11
- 238000007906 compression Methods 0.000 claims description 11
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 9
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims description 9
- 239000000203 mixture Substances 0.000 claims description 9
- 229920001577 copolymer Polymers 0.000 claims description 8
- 125000005647 linker group Chemical group 0.000 claims description 8
- 239000000843 powder Substances 0.000 claims description 7
- 125000003055 glycidyl group Chemical group C(C1CO1)* 0.000 claims description 5
- 229920001451 polypropylene glycol Polymers 0.000 claims description 5
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 4
- 238000000137 annealing Methods 0.000 claims description 4
- 238000004132 cross linking Methods 0.000 claims description 4
- 239000000600 sorbitol Substances 0.000 claims description 4
- 230000001954 sterilising effect Effects 0.000 claims description 4
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims description 3
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 claims description 3
- 229930195725 Mannitol Natural products 0.000 claims description 3
- 239000002202 Polyethylene glycol Substances 0.000 claims description 3
- 239000004721 Polyphenylene oxide Substances 0.000 claims description 3
- 125000004181 carboxyalkyl group Chemical group 0.000 claims description 3
- 239000003795 chemical substances by application Substances 0.000 claims description 3
- 239000000594 mannitol Substances 0.000 claims description 3
- 235000010355 mannitol Nutrition 0.000 claims description 3
- 229920000570 polyether Polymers 0.000 claims description 3
- 229920001223 polyethylene glycol Polymers 0.000 claims description 3
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 2
- GOOHAUXETOMSMM-UHFFFAOYSA-N Propylene oxide Chemical compound CC1CO1 GOOHAUXETOMSMM-UHFFFAOYSA-N 0.000 claims description 2
- ZJCCRDAZUWHFQH-UHFFFAOYSA-N Trimethylolpropane Chemical compound CCC(CO)(CO)CO ZJCCRDAZUWHFQH-UHFFFAOYSA-N 0.000 claims description 2
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical class CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims description 2
- 125000005111 carboxyalkoxy group Chemical group 0.000 claims description 2
- GPLRAVKSCUXZTP-UHFFFAOYSA-N diglycerol Chemical compound OCC(O)COCC(O)CO GPLRAVKSCUXZTP-UHFFFAOYSA-N 0.000 claims description 2
- WXZMFSXDPGVJKK-UHFFFAOYSA-N pentaerythritol Chemical compound OCC(CO)(CO)CO WXZMFSXDPGVJKK-UHFFFAOYSA-N 0.000 claims description 2
- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical class CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 claims description 2
- AGNTUZCMJBTHOG-UHFFFAOYSA-N 3-[3-(2,3-dihydroxypropoxy)-2-hydroxypropoxy]propane-1,2-diol Chemical compound OCC(O)COCC(O)COCC(O)CO AGNTUZCMJBTHOG-UHFFFAOYSA-N 0.000 claims 1
- 229920000223 polyglycerol Polymers 0.000 claims 1
- 230000028993 immune response Effects 0.000 abstract description 6
- 238000005461 lubrication Methods 0.000 abstract description 3
- 238000006243 chemical reaction Methods 0.000 description 5
- 239000011248 coating agent Substances 0.000 description 5
- 238000000576 coating method Methods 0.000 description 5
- 239000000080 wetting agent Substances 0.000 description 4
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 239000000919 ceramic Substances 0.000 description 3
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 description 3
- 210000000629 knee joint Anatomy 0.000 description 3
- 238000004806 packaging method and process Methods 0.000 description 3
- 239000002245 particle Substances 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- 208000003076 Osteolysis Diseases 0.000 description 2
- MCMNRKCIXSYSNV-UHFFFAOYSA-N Zirconium dioxide Chemical compound O=[Zr]=O MCMNRKCIXSYSNV-UHFFFAOYSA-N 0.000 description 2
- 238000011882 arthroplasty Methods 0.000 description 2
- 210000000988 bone and bone Anatomy 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 210000001145 finger joint Anatomy 0.000 description 2
- 239000011888 foil Substances 0.000 description 2
- 125000000524 functional group Chemical group 0.000 description 2
- 210000001624 hip Anatomy 0.000 description 2
- 210000004394 hip joint Anatomy 0.000 description 2
- 230000003993 interaction Effects 0.000 description 2
- 210000003127 knee Anatomy 0.000 description 2
- 208000029791 lytic metastatic bone lesion Diseases 0.000 description 2
- 239000011159 matrix material Substances 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 230000017074 necrotic cell death Effects 0.000 description 2
- 210000001738 temporomandibular joint Anatomy 0.000 description 2
- 238000009736 wetting Methods 0.000 description 2
- 210000002517 zygapophyseal joint Anatomy 0.000 description 2
- 102000004506 Blood Proteins Human genes 0.000 description 1
- 108010017384 Blood Proteins Proteins 0.000 description 1
- IMROMDMJAWUWLK-UHFFFAOYSA-N Ethenol Chemical compound OC=C IMROMDMJAWUWLK-UHFFFAOYSA-N 0.000 description 1
- 229930194542 Keto Natural products 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- 229910001069 Ti alloy Inorganic materials 0.000 description 1
- WAIPAZQMEIHHTJ-UHFFFAOYSA-N [Cr].[Co] Chemical class [Cr].[Co] WAIPAZQMEIHHTJ-UHFFFAOYSA-N 0.000 description 1
- 238000005299 abrasion Methods 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 125000004183 alkoxy alkyl group Chemical group 0.000 description 1
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 1
- 125000003368 amide group Chemical group 0.000 description 1
- 238000004873 anchoring Methods 0.000 description 1
- 210000000544 articulatio talocruralis Anatomy 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 229940105990 diglycerin Drugs 0.000 description 1
- 210000002310 elbow joint Anatomy 0.000 description 1
- 210000003414 extremity Anatomy 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 210000000521 femorotibial joint Anatomy 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 125000001153 fluoro group Chemical group F* 0.000 description 1
- 230000005251 gamma ray Effects 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 125000005113 hydroxyalkoxy group Chemical group 0.000 description 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 description 1
- 230000000899 immune system response Effects 0.000 description 1
- 210000001503 joint Anatomy 0.000 description 1
- 125000000468 ketone group Chemical group 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 238000010030 laminating Methods 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 210000002540 macrophage Anatomy 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 239000012299 nitrogen atmosphere Substances 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- YHHSONZFOIEMCP-UHFFFAOYSA-O phosphocholine Chemical group C[N+](C)(C)CCOP(O)(O)=O YHHSONZFOIEMCP-UHFFFAOYSA-O 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 229920005604 random copolymer Polymers 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 210000000323 shoulder joint Anatomy 0.000 description 1
- 238000000807 solvent casting Methods 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L23/00—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
- C08L23/02—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers not modified by chemical after-treatment
- C08L23/04—Homopolymers or copolymers of ethene
- C08L23/06—Polyethene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/32—Joints for the hip
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L23/00—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
- C08L23/02—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers not modified by chemical after-treatment
- C08L23/04—Homopolymers or copolymers of ethene
- C08L23/08—Copolymers of ethene
- C08L23/0846—Copolymers of ethene with unsaturated hydrocarbons containing other atoms than carbon or hydrogen atoms
- C08L23/0869—Acids or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L23/00—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
- C08L23/02—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers not modified by chemical after-treatment
- C08L23/04—Homopolymers or copolymers of ethene
- C08L23/08—Copolymers of ethene
- C08L23/0846—Copolymers of ethene with unsaturated hydrocarbons containing other atoms than carbon or hydrogen atoms
- C08L23/0869—Acids or derivatives thereof
- C08L23/0884—Epoxide containing esters
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2312/00—Crosslinking
- C08L2312/06—Crosslinking by radiation
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L51/00—Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
- C08L51/06—Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers grafted on to homopolymers or copolymers of aliphatic hydrocarbons containing only one carbon-to-carbon double bond
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L53/00—Compositions of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
- C08L71/02—Polyalkylene oxides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84024106P | 2006-08-25 | 2006-08-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200707186B true ZA200707186B (en) | 2009-09-30 |
Family
ID=38800793
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200707186A ZA200707186B (en) | 2006-08-25 | 2007-08-24 | Bearing material of medical implant and method for making it |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US7683133B2 (de) |
| EP (1) | EP1891987B1 (de) |
| JP (1) | JP5143501B2 (de) |
| CN (1) | CN101130109A (de) |
| AT (1) | ATE481989T1 (de) |
| AU (1) | AU2007211885B2 (de) |
| DE (1) | DE602007009345D1 (de) |
| DK (1) | DK1891987T3 (de) |
| ES (1) | ES2350708T3 (de) |
| ZA (1) | ZA200707186B (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8524884B2 (en) * | 2001-10-30 | 2013-09-03 | Colorado State University Research Foundation | Outer layer material having entanglement of hydrophobic polymer hostblended with a maleated hydrophobic polymer co-host, and hydrophilic polymer guest |
| US7662954B2 (en) | 2001-10-30 | 2010-02-16 | Colorado State University Research Foundation | Outer layer having entanglement of hydrophobic polymer host and hydrophilic polymer guest |
| EP1924299B1 (de) * | 2005-08-18 | 2009-11-25 | Zimmer GmbH | Ultrahochmolekulare polyethylen-artikel und verfahren zur herstellung von ultrahochmolekularen polyethylen-artikeln |
| DK1891987T3 (da) * | 2006-08-25 | 2010-12-13 | Depuy Products Inc | Bæremateriale for medicinsk implantat |
| EP2578248B1 (de) | 2007-04-10 | 2021-05-19 | Zimmer, Inc. | Antioxidans-stabilisiertes, vernetztes Polyethylen mit ultrahohem Molekulargewicht für Medizingeräteanwendungen |
| US8664290B2 (en) | 2007-04-10 | 2014-03-04 | Zimmer, Inc. | Antioxidant stabilized crosslinked ultra-high molecular weight polyethylene for medical device applications |
| JP5571580B2 (ja) | 2008-01-30 | 2014-08-13 | ジンマー，インコーポレイティド | 低剛性の整形外科部品 |
| US20090234454A1 (en) * | 2008-03-12 | 2009-09-17 | Nonlinear Technologies Ltd. | Spinal Implant With Structural Support And Bone Interface Surfaces Formed from UHMWPE |
| JP4806717B2 (ja) * | 2009-06-25 | 2011-11-02 | 株式会社沖データ | 画像処理システム |
| GB0922339D0 (en) | 2009-12-21 | 2010-02-03 | Mcminn Derek J W | Acetabular cup prothesis and introducer thereof |
| US20140024736A1 (en) * | 2010-11-03 | 2014-01-23 | Zimmer, Inc. | Polymer articles having chemically bonded agents and methods of making the same |
| CN102526802B (zh) * | 2012-01-06 | 2013-10-30 | 中国矿业大学 | 一种仿生软骨材料与硬面基底结合的仿生材料的制备工艺 |
| WO2015050851A1 (en) | 2013-10-01 | 2015-04-09 | Zimmer, Inc. | Polymer compositions comprising one or more protected antioxidants |
| EP3116941A1 (de) | 2014-03-12 | 2017-01-18 | Zimmer, Inc. | Schmelzstabilisiertes polyethylen mit ultrahohem molekulargewicht und verfahren zu seiner herstellung |
| CN107207741B (zh) | 2014-12-03 | 2021-05-11 | 捷迈有限公司 | 注入抗氧剂的超高分子量聚乙烯 |
| JP2019146747A (ja) * | 2018-02-27 | 2019-09-05 | 賀代 小久保 | 歯科用インプラントの埋入方法 |
Family Cites Families (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE601705A (de) | 1960-03-23 | |||
| JPS5018909B2 (de) | 1971-11-09 | 1975-07-02 | ||
| US3954927A (en) | 1973-02-05 | 1976-05-04 | Sun Ventures, Inc. | Method of making porous objects of ultra high molecular weight polyethylene |
| US4454612A (en) | 1980-05-07 | 1984-06-19 | Biomet, Inc. | Prosthesis formation having solid and porous polymeric components |
| CA1142883A (en) | 1980-09-04 | 1983-03-15 | George White | Process for irradiation of polyethylene |
| JPS60252645A (ja) | 1984-05-30 | 1985-12-13 | Sekisui Chem Co Ltd | 超高分子量ポリエチレン組成物 |
| EP0148743B1 (de) | 1984-01-06 | 1991-04-10 | Mitsui Petrochemical Industries, Ltd. | Thermoplastische Harzzusammensetzungen |
| EP0175769B1 (de) | 1984-03-29 | 1990-10-31 | Hoechst Celanese Corporation | Polyäthylen-giesszusammensetzung und deren verfahren |
| US4778601A (en) | 1984-10-09 | 1988-10-18 | Millipore Corporation | Microporous membranes of ultrahigh molecular weight polyethylene |
| DD227328A1 (de) | 1984-10-10 | 1985-09-18 | Adw Ddr | Faserverstaerktes implantat aus ultrahochmolekularem polyethylen |
| EP0198904A1 (de) | 1984-10-24 | 1986-10-29 | ZACHARIADES, Anagnostis E. | Polyäthylenerzeugnisse ultrahochmolekularen gewichts einschliesslich vaskularprothesen und verfahren hinsichtlich deren verwendung im pseudogelzustand |
| US4880843A (en) | 1988-03-28 | 1989-11-14 | Hoechst Celanese Corporation | Composition and process for making porous articles from ultra high molecular weight polyethylene |
| US5275838A (en) | 1990-02-28 | 1994-01-04 | Massachusetts Institute Of Technology | Immobilized polyethylene oxide star molecules for bioapplications |
| JP2957021B2 (ja) | 1991-01-25 | 1999-10-04 | テルモ株式会社 | 医療用材料および医療用器具ならびに医療用材料の製造方法 |
| US5288818A (en) | 1991-08-20 | 1994-02-22 | Exxon Chemical Patents Inc. | Method for separating a water soluble noble metal catalyst from a noble metal catalyzed hydroformylation reaction |
| US5414049A (en) | 1993-06-01 | 1995-05-09 | Howmedica Inc. | Non-oxidizing polymeric medical implant |
| US5593719A (en) | 1994-03-29 | 1997-01-14 | Southwest Research Institute | Treatments to reduce frictional wear between components made of ultra-high molecular weight polyethylene and metal alloys |
| ES2138699T3 (es) * | 1994-04-11 | 2000-01-16 | Bristol Myers Squibb Co | Implante de material compuesto polimerico y procedimiento de fabricacion. |
| CA2166450C (en) | 1995-01-20 | 2008-03-25 | Ronald Salovey | Chemically crosslinked ultrahigh molecular weight polyethylene for artificial human joints |
| WO1998001085A1 (en) | 1996-07-09 | 1998-01-15 | The Orthopaedic Hospital | Crosslinking of polyethylene for low wear using radiation and thermal treatments |
| US5594055A (en) | 1995-02-22 | 1997-01-14 | Hoffmann-La Roche Inc. | Antioxidant system for polyolefins |
| US5879400A (en) | 1996-02-13 | 1999-03-09 | Massachusetts Institute Of Technology | Melt-irradiated ultra high molecular weight polyethylene prosthetic devices |
| US5721334A (en) | 1996-02-16 | 1998-02-24 | Newyork Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery | Process for producing ultra-high molecular weight low modulus polyethylene shaped articles via controlled pressure and temperature and compositions and articles produced therefrom |
| US5844027A (en) | 1996-05-03 | 1998-12-01 | Ciba Specialty Chemicals Corporation | Stabilizer composition for thermoplastic materials |
| US6228900B1 (en) | 1996-07-09 | 2001-05-08 | The Orthopaedic Hospital And University Of Southern California | Crosslinking of polyethylene for low wear using radiation and thermal treatments |
| US5827904A (en) | 1996-09-27 | 1998-10-27 | Hahn; David | Medical implant composition |
| US6017975A (en) | 1996-10-02 | 2000-01-25 | Saum; Kenneth Ashley | Process for medical implant of cross-linked ultrahigh molecular weight polyethylene having improved balance of wear properties and oxidation resistance |
| EP1028760B1 (de) | 1996-10-15 | 2004-04-14 | Orthopaedic Hospital | Verschleissfestes vernetztes polyethylen mit oberflächengradienten |
| US5945457A (en) * | 1997-10-01 | 1999-08-31 | A.V. Topchiev Institute Of Petrochemical Synthesis, Russian Academy Of Science | Process for preparing biologically compatible polymers and their use in medical devices |
| EP0995449A1 (de) | 1998-10-21 | 2000-04-26 | Sulzer Orthopädie AG | UHMW-Polyethylen für Implantate |
| US6379741B1 (en) | 1998-11-30 | 2002-04-30 | The Regents Of The University Of California | Plasma-assisted surface modification of polymers for medical device applications |
| SE9900519D0 (sv) | 1999-02-17 | 1999-02-17 | Lars Lidgren | A method for the preparation of UHMWPE doped with an antioxidant and an implant made thereof |
| US6365089B1 (en) | 1999-09-24 | 2002-04-02 | Zimmer, Inc. | Method for crosslinking UHMWPE in an orthopaedic implant |
| US6395799B1 (en) | 2000-02-21 | 2002-05-28 | Smith & Nephew, Inc. | Electromagnetic and mechanical wave energy treatments of UHMWPE |
| EP1276436B1 (de) | 2000-04-27 | 2008-12-31 | Orthopaedic Hospital | Oxidationsbeständige und abriebfeste polyethylene fur menschlichen gelenkersatz und verfahren zu deren herstellung |
| DE60122360T2 (de) | 2000-09-29 | 2007-08-09 | DePuy Orthopaedics, Inc., Warsaw | Behandlung eines bestrahlten vorformlings eines prothetischen lagerelementes aus polyethylen mit einem überkritischen fluid |
| US6818172B2 (en) | 2000-09-29 | 2004-11-16 | Depuy Products, Inc. | Oriented, cross-linked UHMWPE molding for orthopaedic applications |
| US7662954B2 (en) | 2001-10-30 | 2010-02-16 | Colorado State University Research Foundation | Outer layer having entanglement of hydrophobic polymer host and hydrophilic polymer guest |
| WO2003049930A1 (en) | 2001-12-12 | 2003-06-19 | Depuy Products, Inc. | Orthopaedic device and method for making same |
| US6743388B2 (en) | 2001-12-31 | 2004-06-01 | Advanced Cardiovascular Systems, Inc. | Process of making polymer articles |
| WO2003059200A1 (en) | 2002-01-04 | 2003-07-24 | Massachusetts General Hospital | A high modulus crosslinked polyethylene with reduced residual free radical concentration prepared below the melt |
| US7819925B2 (en) * | 2002-01-28 | 2010-10-26 | Depuy Products, Inc. | Composite prosthetic bearing having a crosslinked articulating surface and method for making the same |
| US7186364B2 (en) | 2002-01-28 | 2007-03-06 | Depuy Products, Inc. | Composite prosthetic bearing constructed of polyethylene and an ethylene-acrylate copolymer and method for making the same |
| AU2003211465A1 (en) | 2002-02-19 | 2003-09-09 | Kazuhiko Ishihara | Artificial joint member made of polymeric material |
| US7238744B2 (en) | 2002-04-12 | 2007-07-03 | Daramic, Inc. | Ultrahigh molecular weight polyethylene articles and method of manufacture |
| US20050019366A1 (en) | 2002-12-31 | 2005-01-27 | Zeldis Jerome B. | Drug-coated stents and methods of use therefor |
| US7431874B2 (en) | 2003-01-16 | 2008-10-07 | Massachusetts General Hospital | Methods for making oxidation resistant polymeric material |
| US7938861B2 (en) | 2003-04-15 | 2011-05-10 | Depuy Products, Inc. | Implantable orthopaedic device and method for making the same |
| US20040265165A1 (en) | 2003-06-30 | 2004-12-30 | Depuy Products, Inc. | Free radical quench process for irradiated ultrahigh molecular weight polyethylene |
| US20040262809A1 (en) | 2003-06-30 | 2004-12-30 | Smith Todd S. | Crosslinked polymeric composite for orthopaedic implants |
| US7214764B2 (en) | 2003-06-30 | 2007-05-08 | Depuy Products, Inc. | Free radical quench process for irradiated ultrahigh molecular weight polyethylene |
| US20050065307A1 (en) * | 2003-09-19 | 2005-03-24 | Depuy Products, Inc. | Medical implant or medical implant part comprising porous UHMWPE and process for producing the same |
| US7205051B2 (en) * | 2003-09-30 | 2007-04-17 | Depuy Products, Inc. | Medical implant or medical implant part |
| US7384430B2 (en) | 2004-06-30 | 2008-06-10 | Depuy Products, Inc. | Low crystalline polymeric material for orthopaedic implants and an associated method |
| US7879275B2 (en) | 2004-12-30 | 2011-02-01 | Depuy Products, Inc. | Orthopaedic bearing and method for making the same |
| US7896921B2 (en) | 2004-12-30 | 2011-03-01 | Depuy Products, Inc. | Orthopaedic bearing and method for making the same |
| US8343230B2 (en) | 2005-09-22 | 2013-01-01 | Depuy Products, Inc. | Orthopaedic bearing material |
| DK1891987T3 (da) * | 2006-08-25 | 2010-12-13 | Depuy Products Inc | Bæremateriale for medicinsk implantat |
-
2007
- 2007-07-18 DK DK07252847.4T patent/DK1891987T3/da active
- 2007-07-18 ES ES07252847T patent/ES2350708T3/es active Active
- 2007-07-18 AT AT07252847T patent/ATE481989T1/de active
- 2007-07-18 EP EP07252847A patent/EP1891987B1/de not_active Not-in-force
- 2007-07-18 DE DE602007009345T patent/DE602007009345D1/de active Active
- 2007-08-22 AU AU2007211885A patent/AU2007211885B2/en not_active Ceased
- 2007-08-23 US US11/844,195 patent/US7683133B2/en active Active
- 2007-08-24 CN CNA2007101468574A patent/CN101130109A/zh active Pending
- 2007-08-24 JP JP2007218760A patent/JP5143501B2/ja not_active Expired - Fee Related
- 2007-08-24 ZA ZA200707186A patent/ZA200707186B/en unknown
-
2010
- 2010-02-02 US US12/698,878 patent/US20100137522A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ATE481989T1 (de) | 2010-10-15 |
| JP5143501B2 (ja) | 2013-02-13 |
| JP2008114045A (ja) | 2008-05-22 |
| AU2007211885B2 (en) | 2012-09-20 |
| DK1891987T3 (da) | 2010-12-13 |
| US20080071026A1 (en) | 2008-03-20 |
| EP1891987A3 (de) | 2008-04-02 |
| US7683133B2 (en) | 2010-03-23 |
| DE602007009345D1 (de) | 2010-11-04 |
| CN101130109A (zh) | 2008-02-27 |
| EP1891987A2 (de) | 2008-02-27 |
| US20100137522A1 (en) | 2010-06-03 |
| ES2350708T3 (es) | 2011-01-26 |
| AU2007211885A1 (en) | 2008-03-13 |
| EP1891987B1 (de) | 2010-09-22 |
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