DK1779877T3 - Bæremateriale for medicinske implantater - Google Patents

Bæremateriale for medicinske implantater

Info

Publication number
DK1779877T3
DK1779877T3 DK06255075.1T DK06255075T DK1779877T3 DK 1779877 T3 DK1779877 T3 DK 1779877T3 DK 06255075 T DK06255075 T DK 06255075T DK 1779877 T3 DK1779877 T3 DK 1779877T3
Authority
DK
Denmark
Prior art keywords
medical implants
carrying material
agent
matrix
medical implant
Prior art date
Application number
DK06255075.1T
Other languages
English (en)
Inventor
Richard S King
Mark D Hanes
Original Assignee
Depuy Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Depuy Products Inc filed Critical Depuy Products Inc
Application granted granted Critical
Publication of DK1779877T3 publication Critical patent/DK1779877T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/402—Anaestetics, analgesics, e.g. lidocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L23/00—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
    • C08L23/02—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers not modified by chemical after-treatment
    • C08L23/04—Homopolymers or copolymers of ethene
    • C08L23/06—Polyethene
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2312/00—Crosslinking
    • C08L2312/06—Crosslinking by radiation
DK06255075.1T 2005-09-30 2006-09-29 Bæremateriale for medicinske implantater DK1779877T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11/241,136 US20070077268A1 (en) 2005-09-30 2005-09-30 Hydrophobic carrier modified implants for beneficial agent delivery

Publications (1)

Publication Number Publication Date
DK1779877T3 true DK1779877T3 (da) 2011-03-14

Family

ID=37808480

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06255075.1T DK1779877T3 (da) 2005-09-30 2006-09-29 Bæremateriale for medicinske implantater

Country Status (6)

Country Link
US (1) US20070077268A1 (da)
EP (1) EP1779877B1 (da)
AT (1) ATE491478T1 (da)
DE (1) DE602006018845D1 (da)
DK (1) DK1779877T3 (da)
ES (1) ES2356253T3 (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2441608T3 (es) * 2005-08-18 2014-02-05 Zimmer Gmbh Artículos de polietileno de peso molecular ultra-alto y métodos para formar artículos de polietileno de peso molecular ulra-alto
ES2378721T3 (es) 2007-04-10 2012-04-17 Zimmer, Inc. Polietileno reticulado de peso molecular ultra alto estabilizado por antioxidantes para aplicaciones en dispositivos médicos
US8664290B2 (en) 2007-04-10 2014-03-04 Zimmer, Inc. Antioxidant stabilized crosslinked ultra-high molecular weight polyethylene for medical device applications
US8652212B2 (en) 2008-01-30 2014-02-18 Zimmer, Inc. Orthopedic component of low stiffness
US8133436B2 (en) 2008-08-05 2012-03-13 Howmedica Osteonics Corp. Polyethylene cross-linked with an anthocyanin
EP2346941A1 (en) * 2008-11-20 2011-07-27 Zimmer GmbH Polyethylene materials
AU2009340512A1 (en) 2009-02-19 2011-09-01 Smith & Nephew Orthopaedics Ag Medical implant producing wear particles with benign body response
WO2010096771A2 (en) 2009-02-20 2010-08-26 The General Hospital Corporation Dba High temperature melting
CA2760538A1 (en) * 2009-05-04 2010-11-11 Smith & Nephew, Inc. Synergistic effects of blending multiple additives in uhmwpe
US20110034990A1 (en) * 2009-08-06 2011-02-10 Alexander Borck Biocorrodible implant with active coating
EP2289575B1 (de) * 2009-08-06 2017-07-05 Biotronik VI Patent AG Medizinisches Implantat enthaltend eine antioxidative Substanz
US8399535B2 (en) 2010-06-10 2013-03-19 Zimmer, Inc. Polymer [[s]] compositions including an antioxidant
US9708467B2 (en) 2013-10-01 2017-07-18 Zimmer, Inc. Polymer compositions comprising one or more protected antioxidants
WO2015057943A2 (en) 2013-10-17 2015-04-23 The General Hospital Corporation Peroxide cross-linking and high temperature melting
US10184031B2 (en) 2014-03-12 2019-01-22 Zimmer, Inc. Melt-stabilized ultra high molecular weight polyethylene and method of making the same
JP2015006444A (ja) * 2014-09-19 2015-01-15 スミス・アンド・ネフュー・オルソペディクス・アーゲー 良好な身体応答を示す磨耗粒子を生じる医療用インプラント
CA2969751C (en) 2014-12-03 2020-09-22 Zimmer, Inc. Antioxidant-infused ultra high molecular weight polyethylene
GB201503583D0 (en) * 2015-03-03 2015-04-15 Isis Innovation A method of providing a radio-opaque polymer element
US20180200185A1 (en) 2015-07-23 2018-07-19 Novaflux, Inc Implants and constructs including hollow fibers
AU2017261160A1 (en) * 2016-05-02 2018-11-22 The General Hospital Corporation Implant surfaces for pain control
US11667762B2 (en) 2017-08-29 2023-06-06 The General Hospital Corporation UV-initiated reactions in polymeric materials
CN113289060A (zh) * 2020-05-03 2021-08-24 深圳海思医疗有限公司 组合物及应用、关节植入物型材、关节植入物及制备方法

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL262650A (da) * 1960-03-23
US3954927A (en) * 1973-02-05 1976-05-04 Sun Ventures, Inc. Method of making porous objects of ultra high molecular weight polyethylene
US4454612A (en) * 1980-05-07 1984-06-19 Biomet, Inc. Prosthesis formation having solid and porous polymeric components
EP0148743B1 (en) * 1984-01-06 1991-04-10 Mitsui Petrochemical Industries, Ltd. Thermoplastic resin composition
US4778601A (en) * 1984-10-09 1988-10-18 Millipore Corporation Microporous membranes of ultrahigh molecular weight polyethylene
US4880843A (en) * 1988-03-28 1989-11-14 Hoechst Celanese Corporation Composition and process for making porous articles from ultra high molecular weight polyethylene
US5275838A (en) * 1990-02-28 1994-01-04 Massachusetts Institute Of Technology Immobilized polyethylene oxide star molecules for bioapplications
JP2957021B2 (ja) * 1991-01-25 1999-10-04 テルモ株式会社 医療用材料および医療用器具ならびに医療用材料の製造方法
US5288818A (en) * 1991-08-20 1994-02-22 Exxon Chemical Patents Inc. Method for separating a water soluble noble metal catalyst from a noble metal catalyzed hydroformylation reaction
US5414049A (en) * 1993-06-01 1995-05-09 Howmedica Inc. Non-oxidizing polymeric medical implant
CH686306A5 (de) * 1993-09-17 1996-02-29 Ciba Geigy Ag 3-Aryl-benzofuranone als Stabilisatoren.
US5593719A (en) * 1994-03-29 1997-01-14 Southwest Research Institute Treatments to reduce frictional wear between components made of ultra-high molecular weight polyethylene and metal alloys
CA2166450C (en) * 1995-01-20 2008-03-25 Ronald Salovey Chemically crosslinked ultrahigh molecular weight polyethylene for artificial human joints
WO1998001085A1 (en) * 1996-07-09 1998-01-15 The Orthopaedic Hospital Crosslinking of polyethylene for low wear using radiation and thermal treatments
US5594055A (en) * 1995-02-22 1997-01-14 Hoffmann-La Roche Inc. Antioxidant system for polyolefins
US5879400A (en) * 1996-02-13 1999-03-09 Massachusetts Institute Of Technology Melt-irradiated ultra high molecular weight polyethylene prosthetic devices
US5721334A (en) * 1996-02-16 1998-02-24 Newyork Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery Process for producing ultra-high molecular weight low modulus polyethylene shaped articles via controlled pressure and temperature and compositions and articles produced therefrom
US5844027A (en) * 1996-05-03 1998-12-01 Ciba Specialty Chemicals Corporation Stabilizer composition for thermoplastic materials
US6228900B1 (en) * 1996-07-09 2001-05-08 The Orthopaedic Hospital And University Of Southern California Crosslinking of polyethylene for low wear using radiation and thermal treatments
US5827904A (en) * 1996-09-27 1998-10-27 Hahn; David Medical implant composition
US6017975A (en) * 1996-10-02 2000-01-25 Saum; Kenneth Ashley Process for medical implant of cross-linked ultrahigh molecular weight polyethylene having improved balance of wear properties and oxidation resistance
WO1998016258A1 (en) * 1996-10-15 1998-04-23 The Orthopaedic Hospital Wear resistant surface-gradient cross-linked polyethylene
EP0995449A1 (de) * 1998-10-21 2000-04-26 Sulzer Orthopädie AG UHMW-Polyethylen für Implantate
US6379741B1 (en) * 1998-11-30 2002-04-30 The Regents Of The University Of California Plasma-assisted surface modification of polymers for medical device applications
SE9900519D0 (sv) * 1999-02-17 1999-02-17 Lars Lidgren A method for the preparation of UHMWPE doped with an antioxidant and an implant made thereof
US6365089B1 (en) * 1999-09-24 2002-04-02 Zimmer, Inc. Method for crosslinking UHMWPE in an orthopaedic implant
US6395799B1 (en) * 2000-02-21 2002-05-28 Smith & Nephew, Inc. Electromagnetic and mechanical wave energy treatments of UHMWPE
WO2001080778A1 (en) * 2000-04-27 2001-11-01 The Orthopaedic Hospital Oxidation-resistant and wear-resistant polyethylenes for human joint replacements and methods for making them
US6818172B2 (en) * 2000-09-29 2004-11-16 Depuy Products, Inc. Oriented, cross-linked UHMWPE molding for orthopaedic applications
US7662954B2 (en) * 2001-10-30 2010-02-16 Colorado State University Research Foundation Outer layer having entanglement of hydrophobic polymer host and hydrophilic polymer guest
JP2005511216A (ja) * 2001-12-12 2005-04-28 デピュイ・プロダクツ・インコーポレイテッド 整形外科装置およびその作製方法
CA2471771C (en) * 2002-01-04 2012-01-03 Massachusetts General Hospital A high modulus crosslinked polyethylene with reduced residual free radical concentration prepared below the melt
US7819925B2 (en) * 2002-01-28 2010-10-26 Depuy Products, Inc. Composite prosthetic bearing having a crosslinked articulating surface and method for making the same
US7186364B2 (en) * 2002-01-28 2007-03-06 Depuy Products, Inc. Composite prosthetic bearing constructed of polyethylene and an ethylene-acrylate copolymer and method for making the same
US7238744B2 (en) * 2002-04-12 2007-07-03 Daramic, Inc. Ultrahigh molecular weight polyethylene articles and method of manufacture
US20050019366A1 (en) * 2002-12-31 2005-01-27 Zeldis Jerome B. Drug-coated stents and methods of use therefor
EP2671538A1 (en) * 2003-01-16 2013-12-11 Massachusetts General Hospital Methods For Making Oxidation Resistant Polymeric Material
US7938861B2 (en) * 2003-04-15 2011-05-10 Depuy Products, Inc. Implantable orthopaedic device and method for making the same
US20040265165A1 (en) * 2003-06-30 2004-12-30 Depuy Products, Inc. Free radical quench process for irradiated ultrahigh molecular weight polyethylene
US7214764B2 (en) * 2003-06-30 2007-05-08 Depuy Products, Inc. Free radical quench process for irradiated ultrahigh molecular weight polyethylene
US20040262809A1 (en) * 2003-06-30 2004-12-30 Smith Todd S. Crosslinked polymeric composite for orthopaedic implants
US20050065307A1 (en) * 2003-09-19 2005-03-24 Depuy Products, Inc. Medical implant or medical implant part comprising porous UHMWPE and process for producing the same
US7205051B2 (en) * 2003-09-30 2007-04-17 Depuy Products, Inc. Medical implant or medical implant part
US20060062825A1 (en) * 2004-04-19 2006-03-23 Maria Maccecchini Method of implanting a sterile, active agent-coated material and composition made according to same
US7384430B2 (en) * 2004-06-30 2008-06-10 Depuy Products, Inc. Low crystalline polymeric material for orthopaedic implants and an associated method
WO2006050106A1 (en) * 2004-10-28 2006-05-11 Microchips, Inc. Orthopedic and dental implant devices providing controlled drug delivery
US7335697B2 (en) * 2004-12-23 2008-02-26 Depuy Products, Inc. Polymer composition comprising cross-linked polyethylene and methods for making the same
US7879275B2 (en) * 2004-12-30 2011-02-01 Depuy Products, Inc. Orthopaedic bearing and method for making the same
US7896921B2 (en) * 2004-12-30 2011-03-01 Depuy Products, Inc. Orthopaedic bearing and method for making the same

Also Published As

Publication number Publication date
EP1779877A1 (en) 2007-05-02
ES2356253T3 (es) 2011-04-06
EP1779877B1 (en) 2010-12-15
DE602006018845D1 (de) 2011-01-27
US20070077268A1 (en) 2007-04-05
ATE491478T1 (de) 2011-01-15

Similar Documents

Publication Publication Date Title
DK1779877T3 (da) Bæremateriale for medicinske implantater
DE50309517D1 (de) Interpenetrierende Netzwerke
ATE524121T1 (de) Vorrichtungen zur platzierung eines orthopädischen intervertebralen implantats
WO2006047310A3 (en) Hollow and porous orthopaedic or dental implant that delivers a biological agent
ATE539710T1 (de) Anteriores hybrid-implantat
BRPI0822625B8 (pt) dispositivo espaçador modular para o tratamento de infecções por próteses
BR0203650A (pt) Estentor de auto-articulação
ATE539701T1 (de) Zusammengesetzte schlinge zur behandlung von inkontinenz
EP1596755A4 (en) METHOD FOR PRODUCING OXIDATION-RESISTANT POLYMER MATERIAL
ATE359762T1 (de) Flexible mikrochip-vorrichtungen zur ophthalmologischen und anderen applikation
ATE515995T1 (de) Vorrichtung zur freigabe von bioaktiven substanzen und verfahren zu deren herstellung
DE602004027122D1 (de) Implantatablage-katheter mit elektrolytisch abbaubaren verbindungen
BRPI0706077A (pt) implantes espinhais
DE60232542D1 (de) Gerät zur ablage von geflochtenen prothesen
WO2007076508A3 (en) Implantable graft material
WO2006023130A3 (en) Biodegradable controlled release bioactive agent delivery device
WO2004050133A3 (en) Layered bioresorbable implant
DE602004018106D1 (de) Festes implantat
FR12C0067I1 (fr) Implant oculaire biodegradable
WO2004067044A8 (en) Light-activated adhesive composite, system, and methods
WO2006002366A3 (en) Biodegradable ocular devices, methods and systems
ATE469621T1 (de) Fusionsimplantat mit kontrollierter senkung
DK1343492T3 (da) Behandling af mucositis
ATE539705T1 (de) Chirurgisch implantierbare knieprothese
BR0214571A (pt) métodos para pré-tratar um indivìduo com fotoférese extracorporal e/ou células apoptóticas