ATE418933T1 - Oxidationsbeständige und abriebfeste polyethylene fur menschlichen gelenkersatz und verfahren zu deren herstellung - Google Patents

Oxidationsbeständige und abriebfeste polyethylene fur menschlichen gelenkersatz und verfahren zu deren herstellung

Info

Publication number
ATE418933T1
ATE418933T1 AT01934941T AT01934941T ATE418933T1 AT E418933 T1 ATE418933 T1 AT E418933T1 AT 01934941 T AT01934941 T AT 01934941T AT 01934941 T AT01934941 T AT 01934941T AT E418933 T1 ATE418933 T1 AT E418933T1
Authority
AT
Austria
Prior art keywords
resistant
oxidation
polyethylenes
abrasion
production
Prior art date
Application number
AT01934941T
Other languages
English (en)
Inventor
Harry Mckellop
Fu-Wen Shen
Original Assignee
Orthopaedic Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22742074&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE418933(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Orthopaedic Hospital filed Critical Orthopaedic Hospital
Application granted granted Critical
Publication of ATE418933T1 publication Critical patent/ATE418933T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/16Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/08Radiation
    • A61L2/081Gamma radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C35/00Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
    • B29C35/02Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould
    • B29C35/08Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation
    • B29C35/0805Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using electromagnetic radiation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C35/00Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
    • B29C35/02Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould
    • B29C35/08Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation
    • B29C35/0866Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using particle radiation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C43/00Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
    • B29C43/003Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor characterised by the choice of material
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C48/00Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
    • B29C48/022Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor characterised by the choice of material
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B55/00Preserving, protecting or purifying packages or package contents in association with packaging
    • B65B55/02Sterilising, e.g. of complete packages
    • B65B55/12Sterilising contents prior to, or during, packaging
    • B65B55/16Sterilising contents prior to, or during, packaging by irradiation
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00Processes of treating or compounding macromolecular substances
    • C08J3/28Treatment by wave energy or particle radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/3094Designing or manufacturing processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/32Joints for the hip
    • A61F2/34Acetabular cups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/38Joints for elbows or knees
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/24Materials or treatment for tissue regeneration for joint reconstruction
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C35/00Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
    • B29C35/02Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould
    • B29C35/08Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation
    • B29C35/0805Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using electromagnetic radiation
    • B29C2035/085Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using electromagnetic radiation using gamma-ray
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C35/00Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
    • B29C35/02Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould
    • B29C35/08Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation
    • B29C35/0866Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using particle radiation
    • B29C2035/0877Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using particle radiation using electron radiation, e.g. beta-rays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29KINDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2023/00Use of polyalkenes or derivatives thereof as moulding material
    • B29K2023/04Polymers of ethylene
    • B29K2023/06PE, i.e. polyethylene
    • B29K2023/0658PE, i.e. polyethylene characterised by its molecular weight
    • B29K2023/0683UHMWPE, i.e. ultra high molecular weight polyethylene
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2323/00Characterised by the use of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Derivatives of such polymers
    • C08J2323/02Characterised by the use of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Derivatives of such polymers not modified by chemical after treatment
    • C08J2323/04Homopolymers or copolymers of ethene
    • C08J2323/06Polyethene

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Electromagnetism (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Laminated Bodies (AREA)
  • Non-Disconnectible Joints And Screw-Threaded Joints (AREA)
  • Lining Or Joining Of Plastics Or The Like (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
  • Insulating Bodies (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
AT01934941T 2000-04-27 2001-04-27 Oxidationsbeständige und abriebfeste polyethylene fur menschlichen gelenkersatz und verfahren zu deren herstellung ATE418933T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20052500P 2000-04-27 2000-04-27

Publications (1)

Publication Number Publication Date
ATE418933T1 true ATE418933T1 (de) 2009-01-15

Family

ID=22742074

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01934941T ATE418933T1 (de) 2000-04-27 2001-04-27 Oxidationsbeständige und abriebfeste polyethylene fur menschlichen gelenkersatz und verfahren zu deren herstellung

Country Status (9)

Country Link
US (5) US8796347B2 (de)
EP (3) EP1276436B1 (de)
JP (2) JP4256096B2 (de)
AT (1) ATE418933T1 (de)
AU (2) AU6108301A (de)
DE (1) DE60137212D1 (de)
DK (1) DK1276436T3 (de)
ES (1) ES2317905T3 (de)
WO (1) WO2001080778A1 (de)

Families Citing this family (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050125074A1 (en) * 1995-01-20 2005-06-09 Ronald Salovey Crosslinking of polyethylene for low wear using radiation and thermal treatments
CA2166450C (en) * 1995-01-20 2008-03-25 Ronald Salovey Chemically crosslinked ultrahigh molecular weight polyethylene for artificial human joints
EP0935446B1 (de) 1996-07-09 2007-02-07 Orthopaedic Hospital Vernetzung von polyethylen zur verringerung der abnutzung unter anwendung von strahlung und thermischer behandlung
AU6108301A (en) * 2000-04-27 2001-11-07 Orthopaedic Hospital Oxidation-resistant and wear-resistant polyethylenes for human joint replacements and methods for making them
US6558426B1 (en) 2000-11-28 2003-05-06 Medidea, Llc Multiple-cam, posterior-stabilized knee prosthesis
JP2005511216A (ja) * 2001-12-12 2005-04-28 デピュイ・プロダクツ・インコーポレイテッド 整形外科装置およびその作製方法
EP1369094B1 (de) 2002-05-31 2014-11-26 Zimmer GmbH Implantat und Verfahren zur Herstellung eines steril verpackten Implantats
US20040110853A1 (en) * 2002-08-20 2004-06-10 Wang Louis Chun Process for preparing molded porous articles and the porous articles prepared therefrom
EP2671538A1 (de) 2003-01-16 2013-12-11 Massachusetts General Hospital Verfahren zur Herstellung von oxidationsbeständigem Polymermaterial
AT412969B (de) * 2003-05-19 2005-09-26 Klaus Dr Lederer Vernetztes, ultra-hochmolekulares polyethylen (uhmw-pe)
US7214764B2 (en) * 2003-06-30 2007-05-08 Depuy Products, Inc. Free radical quench process for irradiated ultrahigh molecular weight polyethylene
CA2554777C (en) 2004-02-03 2012-10-09 Orhun K. Muratoglu Highly crystalline cross-linked oxidation-resistant polyethylene
US7833452B2 (en) 2004-05-11 2010-11-16 The General Hospital Corporation Method for making oxidation resistant polymeric material
US7462318B2 (en) 2004-10-07 2008-12-09 Biomet Manufacturing Corp. Crosslinked polymeric material with enhanced strength and process for manufacturing
US7344672B2 (en) 2004-10-07 2008-03-18 Biomet Manufacturing Corp. Solid state deformation processing of crosslinked high molecular weight polymeric materials
US8262976B2 (en) 2004-10-07 2012-09-11 Biomet Manufacturing Corp. Solid state deformation processing of crosslinked high molecular weight polymeric materials
US7335697B2 (en) * 2004-12-23 2008-02-26 Depuy Products, Inc. Polymer composition comprising cross-linked polyethylene and methods for making the same
US7435372B2 (en) * 2005-03-31 2008-10-14 Zimmer, Inc. Liquid bath annealing of polymers for orthopaedic implants
ES2509884T3 (es) 2005-08-18 2014-10-20 Zimmer Gmbh Artículos de polietileno de peso molecular ultra-alto y métodos para formar artículos de polietileno de peso molecular ultra-alto
AU2006283601B2 (en) 2005-08-22 2011-10-20 The General Hospital Corporation Dba Massachusetts General Hospital Oxidation resistant homogenized polymeric material
US8425815B2 (en) 2005-08-22 2013-04-23 The General Hospital Corporation Highly crystalline polyethylene
US20070043137A1 (en) * 2005-08-22 2007-02-22 The General Hospital Corporation Dba Massachusetts General Hospital Highly cross-linked and wear-resistant polyethylene prepared below the melt
US8343230B2 (en) * 2005-09-22 2013-01-01 Depuy Products, Inc. Orthopaedic bearing material
US20070077268A1 (en) * 2005-09-30 2007-04-05 Depuy Products, Inc. Hydrophobic carrier modified implants for beneficial agent delivery
US7615075B2 (en) * 2005-11-04 2009-11-10 Rush University Medical Center Plastic implant impregnated with a degradation protector
US7812098B2 (en) * 2006-03-31 2010-10-12 Depuy Products, Inc. Bearing material of medical implant having reduced wear rate and method for reducing wear rate
US20070232762A1 (en) * 2006-03-31 2007-10-04 Depuy Products, Inc. Bearing material of medical implant having reduced wear rate and method for reducing wear rate
ITMI20061375A1 (it) * 2006-07-14 2008-01-15 Fabio Conteduca Maeriale protesico sintetico a ridotta ossidabilita' e relativo processo di preparazione
EP1891987B1 (de) 2006-08-25 2010-09-22 DePuy Products, Inc. Material zum Tragen eines medizinischen Implantats
EP2110002B1 (de) * 2007-01-25 2012-04-25 The General Hospital Corporation Verfahren zur herstellung von oxidationsbeständigem vernetztem polymermaterial
AU2008222967B2 (en) 2007-03-02 2012-12-13 Cambridge Polymer Group, Inc. Cross-linking of antioxidant-containing polymers
CA2681475A1 (en) * 2007-03-20 2008-09-25 Smith & Nephew Orthopaedics Ag Oxidation resistant highly-crosslinked uhmwpe
EP2578248B1 (de) * 2007-04-10 2021-05-19 Zimmer, Inc. Antioxidans-stabilisiertes, vernetztes Polyethylen mit ultrahohem Molekulargewicht für Medizingeräteanwendungen
US8664290B2 (en) 2007-04-10 2014-03-04 Zimmer, Inc. Antioxidant stabilized crosslinked ultra-high molecular weight polyethylene for medical device applications
US8641959B2 (en) 2007-07-27 2014-02-04 Biomet Manufacturing, Llc Antioxidant doping of crosslinked polymers to form non-eluting bearing components
AU2008296237A1 (en) 2007-09-04 2009-03-12 Smith & Nephew Orthopaedics Ag Ultra high molecular weight polyethylene for bearing surfaces
US20110035017A1 (en) * 2007-09-25 2011-02-10 Depuy Products, Inc. Prosthesis with cut-off pegs and surgical method
US8715359B2 (en) 2009-10-30 2014-05-06 Depuy (Ireland) Prosthesis for cemented fixation and method for making the prosthesis
US8128703B2 (en) 2007-09-28 2012-03-06 Depuy Products, Inc. Fixed-bearing knee prosthesis having interchangeable components
US8632600B2 (en) 2007-09-25 2014-01-21 Depuy (Ireland) Prosthesis with modular extensions
US9204967B2 (en) 2007-09-28 2015-12-08 Depuy (Ireland) Fixed-bearing knee prosthesis having interchangeable components
CN101848968B (zh) * 2007-11-06 2013-04-17 帝斯曼知识产权资产管理有限公司 用于生产高分子量聚乙烯的方法
US8652212B2 (en) 2008-01-30 2014-02-18 Zimmer, Inc. Orthopedic component of low stiffness
CA2723929A1 (en) * 2008-05-13 2009-11-19 Smith & Nephew Orthopaedics Ag Oxidation resistant highly-crosslinked uhmwpe
JP5311457B2 (ja) * 2008-06-20 2013-10-09 ナカシマメディカル株式会社 人工関節用摺動部材の成形方法及びこの方法によって成形された人工関節用摺動部材
US8187335B2 (en) 2008-06-30 2012-05-29 Depuy Products, Inc. Posterior stabilized orthopaedic knee prosthesis having controlled condylar curvature
US8828086B2 (en) 2008-06-30 2014-09-09 Depuy (Ireland) Orthopaedic femoral component having controlled condylar curvature
US8236061B2 (en) 2008-06-30 2012-08-07 Depuy Products, Inc. Orthopaedic knee prosthesis having controlled condylar curvature
US8206451B2 (en) 2008-06-30 2012-06-26 Depuy Products, Inc. Posterior stabilized orthopaedic prosthesis
US8192498B2 (en) 2008-06-30 2012-06-05 Depuy Products, Inc. Posterior cructiate-retaining orthopaedic knee prosthesis having controlled condylar curvature
US9168145B2 (en) 2008-06-30 2015-10-27 Depuy (Ireland) Posterior stabilized orthopaedic knee prosthesis having controlled condylar curvature
US9119723B2 (en) 2008-06-30 2015-09-01 Depuy (Ireland) Posterior stabilized orthopaedic prosthesis assembly
DE102008047009B4 (de) * 2008-07-11 2020-08-06 Mathys Ag Bettlach Gelenkpfanne mit physiologischer Lastübertragung
WO2010057644A1 (en) 2008-11-20 2010-05-27 Zimmer Gmbh Polyethylene materials
US8933145B2 (en) 2009-02-20 2015-01-13 The General Hospital Corporation High temperature melting
DE102009001145A1 (de) * 2009-02-25 2010-09-09 Leibniz-Institut Für Polymerforschung Dresden E.V. Verfahren zur Aushärtung und Oberflächenfunktionalisierung von Formteilen
ES2617186T3 (es) 2009-05-04 2017-06-15 Smith & Nephew, Inc Efectos sinérgicos de mezclar múltiples aditivos en UHMWPE
US11213397B2 (en) 2009-05-21 2022-01-04 Depuy Ireland Unlimited Company Prosthesis with surfaces having different textures and method of making the prosthesis
US9101476B2 (en) 2009-05-21 2015-08-11 Depuy (Ireland) Prosthesis with surfaces having different textures and method of making the prosthesis
JP4806717B2 (ja) * 2009-06-25 2011-11-02 株式会社沖データ 画像処理システム
EP2319460A1 (de) 2009-10-30 2011-05-11 DePuy Products, Inc. Prothese mit stumpfen Zapfen
EP2319462B1 (de) 2009-10-30 2013-04-03 DePuy Products, Inc. Prothese mit Verbundstoffkomponente
EP2316382B1 (de) 2009-10-30 2014-03-05 DePuy (Ireland) Prothese für zementfreie Verankerung
ES2406154T3 (es) 2009-10-30 2013-06-05 Depuy Products, Inc. Prótesis con extensiones modulares
EP2730253B1 (de) 2009-10-30 2016-03-16 DePuy Synthes Products, LLC Prothese mit Oberflächen unterschiedlicher Texturen
GB0922339D0 (en) 2009-12-21 2010-02-03 Mcminn Derek J W Acetabular cup prothesis and introducer thereof
US20120319332A1 (en) * 2009-12-21 2012-12-20 Mcminn Derek James Wallace Method of Forming a Polymer Component
US9011547B2 (en) 2010-01-21 2015-04-21 Depuy (Ireland) Knee prosthesis system
US8399535B2 (en) 2010-06-10 2013-03-19 Zimmer, Inc. Polymer [[s]] compositions including an antioxidant
US20140131924A1 (en) * 2011-06-15 2014-05-15 Derek James Wallace McMinn Methods of forming a polymeric component
ITVR20110196A1 (it) * 2011-10-21 2013-04-22 Luigi Costa Metodo per la realizzazione di un dispositivo medicale, quale una protesi, in polietilene
US9700651B2 (en) 2012-05-31 2017-07-11 Kyocera Medical Corporation Bearing material and method of producing the same
DE102012112159A1 (de) * 2012-12-12 2014-06-12 Krones Ag Vorrichtung zum Behandeln von Getränken mit Wandungselementen aus Kunststoff
US9237953B2 (en) 2013-03-15 2016-01-19 Depuy (Ireland) Mechanical assembly of pegs to prosthesis
US9586370B2 (en) 2013-08-15 2017-03-07 Biomet Manufacturing, Llc Method for making ultra high molecular weight polyethylene
US9708467B2 (en) 2013-10-01 2017-07-18 Zimmer, Inc. Polymer compositions comprising one or more protected antioxidants
JP6292815B2 (ja) * 2013-10-10 2018-03-14 京セラ株式会社 抗酸化性人工補綴部材
CA2927056A1 (en) 2013-10-17 2015-04-23 The General Hospital Corporation Peroxide cross-linking and high temperature melting
US9144499B2 (en) 2013-12-17 2015-09-29 Depuy (Ireland) Low profile mobile/fixed prosthetic knee systems
DE102013226814A1 (de) * 2013-12-20 2015-06-25 Christof-Herbert Diener Plasmaanlage mit einem separat transportierbaren Gefäß
CA2942565A1 (en) 2014-03-12 2015-09-17 Zimmer, Inc. Melt-stabilized ultra high molecular weight polyethylene and method of making the same
CA2969751C (en) 2014-12-03 2020-09-22 Zimmer, Inc. Antioxidant-infused ultra high molecular weight polyethylene
WO2017021563A1 (es) * 2015-08-03 2017-02-09 Zanini Auto Grup, S.A. Componente de prótesis y procedimiento para su fabricación
DE102016110500B4 (de) 2016-06-07 2019-03-14 Karl Leibinger Medizintechnik Gmbh & Co. Kg Implantatherstellverfahren mittels additivem selektivem Lasersintern und Implantat
US10070959B2 (en) 2016-09-28 2018-09-11 DePuy Synthes Products, Inc. Method of texturing prosthetic implants
JP6340448B1 (ja) * 2017-03-21 2018-06-06 旭化成株式会社 ポリエチレン系重合体パウダー及びその製造方法
WO2019046243A2 (en) 2017-08-29 2019-03-07 The General Hospital Corporation UV-INITIATED REACTIONS IN POLYMERIC MATERIALS
CN107754013B (zh) * 2017-12-04 2020-11-10 四川大学 高抗氧高交联超高分子量聚乙烯人工关节材料及制备方法
CN108950711A (zh) * 2018-09-06 2018-12-07 山东莱威新材料有限公司 一种超高分子量聚乙烯扁平丝及其制备方法
CN111135343B (zh) * 2019-12-19 2021-09-14 江苏集萃先进高分子材料研究所有限公司 一种高交联高抗氧剂掺杂的人工关节假体材料及其制备方法
CN111321474A (zh) * 2020-02-29 2020-06-23 山东新兴安全防护设备股份有限公司 一种超高分子量聚乙烯纤维的生产工艺
US11970600B2 (en) 2021-03-31 2024-04-30 The General Hospital Corporation Di-cumyl peroxide crosslinking of UHMWPE

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4036719A (en) 1973-10-11 1977-07-19 Raychem Corporation Irradiatable polymer composition with improved oxidation resistance
EP0446300B1 (de) 1988-12-02 1996-06-05 E.I. Du Pont De Nemours And Company Lineares polyäthylen von ultrahohem molekulargewicht, gegenstände und verfahren zu deren herstellung
US5505984A (en) 1993-01-21 1996-04-09 England; Garry L. Method for forming biocompatible components using an isostatic press
US5414049A (en) 1993-06-01 1995-05-09 Howmedica Inc. Non-oxidizing polymeric medical implant
WO1995006148A1 (en) * 1993-08-20 1995-03-02 Smith & Nephew Richards, Inc. Self-reinforced ultra-high molecular weight polyethylene composites
AU727279B2 (en) 1995-01-20 2000-12-07 Orthopaedic Hospital Chemically crosslinked ultrahigh molecular weight polyethylene for artificial human joints
CA2166450C (en) 1995-01-20 2008-03-25 Ronald Salovey Chemically crosslinked ultrahigh molecular weight polyethylene for artificial human joints
US5577368A (en) * 1995-04-03 1996-11-26 Johnson & Johnson Professional, Inc. Method for improving wear resistance of polymeric bioimplantable components
CZ295935B6 (cs) * 1996-02-13 2005-12-14 Massachusetts Institute Of Technology Radiačně modifikovaný polyethylen o velmi vysoké molekulové hmotnosti, způsob jeho výroby a lékařská protéza a průmyslový výrobek z něj zhotovené
US8865788B2 (en) 1996-02-13 2014-10-21 The General Hospital Corporation Radiation and melt treated ultra high molecular weight polyethylene prosthetic devices
US5879400A (en) 1996-02-13 1999-03-09 Massachusetts Institute Of Technology Melt-irradiated ultra high molecular weight polyethylene prosthetic devices
US5753182A (en) * 1996-02-14 1998-05-19 Biomet, Inc. Method for reducing the number of free radicals present in ultrahigh molecular weight polyethylene orthopedic components
US5721334A (en) 1996-02-16 1998-02-24 Newyork Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery Process for producing ultra-high molecular weight low modulus polyethylene shaped articles via controlled pressure and temperature and compositions and articles produced therefrom
EP0935446B1 (de) * 1996-07-09 2007-02-07 Orthopaedic Hospital Vernetzung von polyethylen zur verringerung der abnutzung unter anwendung von strahlung und thermischer behandlung
US6228900B1 (en) 1996-07-09 2001-05-08 The Orthopaedic Hospital And University Of Southern California Crosslinking of polyethylene for low wear using radiation and thermal treatments
US5827904A (en) 1996-09-27 1998-10-27 Hahn; David Medical implant composition
US6017975A (en) 1996-10-02 2000-01-25 Saum; Kenneth Ashley Process for medical implant of cross-linked ultrahigh molecular weight polyethylene having improved balance of wear properties and oxidation resistance
WO1998016258A1 (en) 1996-10-15 1998-04-23 The Orthopaedic Hospital Wear resistant surface-gradient cross-linked polyethylene
US6468258B1 (en) 1997-07-18 2002-10-22 Baxter International Inc. Plastic compositions including vitamin E for medical containers and methods for providing such compositions and containers
JP4315261B2 (ja) 1998-02-25 2009-08-19 ナカシマメディカル株式会社 人工関節用摺動部材および製造方法
US6692679B1 (en) 1998-06-10 2004-02-17 Depuy Orthopaedics, Inc. Cross-linked molded plastic bearings
EP0995450B1 (de) 1998-10-21 2002-06-26 Sulzer Orthopädie AG UHMW-Polyethylen für Implantate
EP0995449A1 (de) * 1998-10-21 2000-04-26 Sulzer Orthopädie AG UHMW-Polyethylen für Implantate
SE9900519D0 (sv) 1999-02-17 1999-02-17 Lars Lidgren A method for the preparation of UHMWPE doped with an antioxidant and an implant made thereof
US6355215B1 (en) * 1999-03-10 2002-03-12 Implex Corp. Wear-resistant olefinic medical implant and thermal treatment container therefor
US6627141B2 (en) * 1999-06-08 2003-09-30 Depuy Orthopaedics, Inc. Method for molding a cross-linked preform
US6245276B1 (en) 1999-06-08 2001-06-12 Depuy Orthopaedics, Inc. Method for molding a cross-linked preform
US6143232A (en) * 1999-07-29 2000-11-07 Bristol-Meyers Squibb Company Method of manufacturing an articulating bearing surface for an orthopaedic implant
US6184265B1 (en) * 1999-07-29 2001-02-06 Depuy Orthopaedics, Inc. Low temperature pressure stabilization of implant component
US6794423B1 (en) 1999-07-30 2004-09-21 Stephen Li Fracture-resistant, cross-linked ultra high molecular weight polyethylene shaped material and articles made therefrom
AU6108301A (en) * 2000-04-27 2001-11-07 Orthopaedic Hospital Oxidation-resistant and wear-resistant polyethylenes for human joint replacements and methods for making them
US6503439B1 (en) * 2000-06-15 2003-01-07 Albert H. Burstein Process for forming shaped articles of ultra high molecular weight polyethylene suitable for use as a prosthetic device or a component thereof
KR200222734Y1 (ko) * 2000-10-11 2001-05-15 주식회사디엔브이 자동차 배기관용 연결구
US6547828B2 (en) 2001-02-23 2003-04-15 Smith & Nephew, Inc. Cross-linked ultra-high molecular weight polyethylene for medical implant use
EP2671538A1 (de) 2003-01-16 2013-12-11 Massachusetts General Hospital Verfahren zur Herstellung von oxidationsbeständigem Polymermaterial

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US20150007527A1 (en) 2015-01-08
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US9155817B2 (en) 2015-10-13
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