ATE471941T1 - Verfahren zur herstellung von thiazolopyrimidinen - Google Patents
Verfahren zur herstellung von thiazolopyrimidinenInfo
- Publication number
- ATE471941T1 ATE471941T1 AT04801262T AT04801262T ATE471941T1 AT E471941 T1 ATE471941 T1 AT E471941T1 AT 04801262 T AT04801262 T AT 04801262T AT 04801262 T AT04801262 T AT 04801262T AT E471941 T1 ATE471941 T1 AT E471941T1
- Authority
- AT
- Austria
- Prior art keywords
- thiazolopyrimidines
- producing
- producing thiazolopyrimidines
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000008634 thiazolopyrimidines Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D497/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D497/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D497/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Dermatology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0328243.1A GB0328243D0 (en) | 2003-12-05 | 2003-12-05 | Methods |
| PCT/GB2004/005072 WO2005056563A2 (en) | 2003-12-05 | 2004-12-02 | Process for the preparation of thiazolopyrimidines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE471941T1 true ATE471941T1 (de) | 2010-07-15 |
Family
ID=29764654
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04801262T ATE471941T1 (de) | 2003-12-05 | 2004-12-02 | Verfahren zur herstellung von thiazolopyrimidinen |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US7790883B2 (https=) |
| EP (1) | EP1711505B1 (https=) |
| JP (1) | JP4808629B2 (https=) |
| KR (1) | KR101170188B1 (https=) |
| CN (1) | CN1914213B (https=) |
| AR (1) | AR046750A1 (https=) |
| AT (1) | ATE471941T1 (https=) |
| AU (1) | AU2004296241B2 (https=) |
| BR (1) | BRPI0417300A (https=) |
| CA (1) | CA2546719A1 (https=) |
| DE (1) | DE602004027840D1 (https=) |
| ES (1) | ES2345660T3 (https=) |
| GB (1) | GB0328243D0 (https=) |
| IL (1) | IL175743A (https=) |
| MY (1) | MY143761A (https=) |
| NO (1) | NO20063111L (https=) |
| NZ (2) | NZ547685A (https=) |
| SG (1) | SG149005A1 (https=) |
| TW (1) | TWI347945B (https=) |
| UY (1) | UY28651A1 (https=) |
| WO (1) | WO2005056563A2 (https=) |
| ZA (1) | ZA200604491B (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9903544D0 (sv) * | 1999-10-01 | 1999-10-01 | Astra Pharma Prod | Novel compounds |
| GB2359551A (en) * | 2000-02-23 | 2001-08-29 | Astrazeneca Uk Ltd | Pharmaceutically active pyrimidine derivatives |
| SE0102716D0 (sv) * | 2001-08-14 | 2001-08-14 | Astrazeneca Ab | Novel compounds |
| GB0221828D0 (en) * | 2002-09-20 | 2002-10-30 | Astrazeneca Ab | Novel compound |
| GB0221829D0 (en) * | 2002-09-20 | 2002-10-30 | Astrazeneca Ab | Novel compound |
| GB0328243D0 (en) | 2003-12-05 | 2004-01-07 | Astrazeneca Ab | Methods |
| DK3054936T5 (da) | 2013-10-10 | 2024-03-18 | Eastern Virginia Medical School | 4-((2-hydroxy-3-methoxybenzyl)amino) benzensulfonamid derivater som 12-lipoxygenase inhibitorer |
| GB201807898D0 (en) * | 2018-05-15 | 2018-06-27 | Kancera Ab | New processes and products with increased chiral purity |
Family Cites Families (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2924472A (en) | 1957-06-27 | 1960-02-09 | Gen Motors Corp | Pipe joint seal |
| US3182062A (en) | 1962-02-28 | 1965-05-04 | Smith Kline French Lab | Synthesis of quinoxalines and analogues thereof |
| GB1009477A (en) | 1962-02-13 | 1965-11-10 | Smith Kline French Lab | Novel process for preparing heterocyclic compounds |
| US3318900A (en) | 1964-05-06 | 1967-05-09 | Janssen Pharmaceutica Nv | Derivatives of benzimidazolinyl piperidine |
| BE668603A (https=) | 1964-08-20 | |||
| DE2331223C2 (de) | 1972-06-19 | 1984-11-22 | Kohjin Co., Ltd., Tokio / Tokyo | S-substituierte-2-Thioadenosine, deren 5'-Monophosphate, Verfahren zu deren Herstellung und Arzneimittel, welche diese enthalten |
| JPS5188994A (en) | 1975-02-04 | 1976-08-04 | Shinkijichikan 88 aminoadeninjudotainoseizoho | |
| US4120521A (en) | 1975-08-28 | 1978-10-17 | Rieber & Son Plastic-Industri A/S | Combined mould element and sealing ring |
| EG12406A (en) | 1976-08-12 | 1979-03-31 | Janssen Pharmaceutica Nv | Process for preparing of novel n-aryl-n-(1-l-4-piperidinyl)-arylacetamides |
| GB1600293A (en) | 1977-02-04 | 1981-10-14 | British Oceanics Ltd | Sealing arrangements |
| US4188040A (en) | 1977-04-06 | 1980-02-12 | Firma WOCO Franz-Josef Wolf & Co. | Sealing ring |
| DE2726959A1 (de) | 1977-06-15 | 1979-01-18 | Arlt Christian | Dichteinsatz zum dichten verbinden von zwei rohren |
| FR2421899A1 (fr) | 1978-01-16 | 1979-11-02 | Roussel Uclaf | Nouveaux derives du tetrahydropyridinyl-indole et leurs sels, le procede de preparation et l'application a titre de medicaments de ces nouveaux produits |
| US4410528A (en) | 1980-05-16 | 1983-10-18 | Kyowa Hakko Kogyo Co., Ltd. | Hypotensive piperidine derivatives |
| DE3219522A1 (de) | 1981-10-28 | 1983-12-01 | Denso-Chemie Wedekind Kg, 5090 Leverkusen | Steckmuffendichtung fuer rohre |
| FR2547888B1 (fr) | 1983-06-22 | 1985-12-13 | Sabla Sa | Bague d'etancheite a implants pour tuyaux a emboitement |
| CA1338012C (en) | 1987-04-27 | 1996-01-30 | John Michael Mccall | Pharmaceutically active amines |
| SE8800348L (sv) | 1988-02-03 | 1989-08-04 | Forsheda Ab | Taetningsring och verktyg foer framstaellning daerav |
| FR2659656B1 (fr) | 1990-03-15 | 1994-09-09 | Sanofi Sa | Derives de pyrimidinedione-2,4 et medicaments les contenant. |
| DE4119767A1 (de) | 1991-06-15 | 1992-12-17 | Dresden Arzneimittel | Verfahren zur herstellung von (pyrimid-2-yl-thio- bzw. seleno)-essigsaeurederivaten |
| US5169161A (en) | 1991-09-19 | 1992-12-08 | Hail Mary Rubber Co., Inc. | Symmetrical gasket for pipe joints |
| DE4134089C2 (de) | 1991-10-15 | 1994-10-13 | Dueker Eisenwerk | Schubgesicherte Muffenverbindung |
| DE4229609C2 (de) | 1992-09-04 | 2003-05-08 | Forsheda Stefa Gmbh | Abdichtung zwischen zwei ineinandersteckbaren Teilen |
| US5521197A (en) | 1994-12-01 | 1996-05-28 | Eli Lilly And Company | 3-<1-alkylenearyl>-4-<1,2,3,6-tetrahydropyridinyl>-and 3-<1-alkylenearyl>-4-piperidinyl-1h-indoles: new 5-HT1F agonists |
| DE69628804T2 (de) | 1995-12-08 | 2003-12-18 | Pfizer Inc., New York | Substitutierte heterozyclische Derivate als CRF Antagonisten |
| GB9624482D0 (en) | 1995-12-18 | 1997-01-15 | Zeneca Phaema S A | Chemical compounds |
| SE515033C2 (sv) | 1995-12-27 | 2001-06-05 | Forsheda Ab | Tätningsanordning |
| BR9707495A (pt) | 1996-02-13 | 1999-07-27 | Zeneca Ltd | Derivado de quinazolina processo para a preparação do mesmo composição farmacêutica e processo para a produç o de um efeito antiangiogênico e/ou de redução de permeabilidade vascular em um animal de sangue quente |
| US6291455B1 (en) | 1996-03-05 | 2001-09-18 | Zeneca Limited | 4-anilinoquinazoline derivatives |
| WO1997040035A1 (en) | 1996-04-19 | 1997-10-30 | Neurosearch A/S | 1-(4-piperidyl)-benzimidazoles having neurotrophic activity |
| IL127566A0 (en) | 1996-08-28 | 1999-10-28 | Pfizer | Substituted 6,5-hetero- bicyclic derivatives |
| GB9718972D0 (en) | 1996-09-25 | 1997-11-12 | Zeneca Ltd | Chemical compounds |
| AU5522498A (en) | 1996-12-13 | 1998-07-03 | Merck & Co., Inc. | Substituted aryl piperazines as modulators of chemokine receptor activity |
| GB9714249D0 (en) | 1997-07-08 | 1997-09-10 | Angiogene Pharm Ltd | Vascular damaging agents |
| WO1999004794A1 (en) | 1997-07-25 | 1999-02-04 | Merck & Co., Inc. | Cyclic amine modulators of chemokine receptor activity |
| AR013669A1 (es) | 1997-10-07 | 2001-01-10 | Smithkline Beecham Corp | Compuestos y metodos |
| NZ504800A (en) | 1997-11-28 | 2001-10-26 | Sumitomo Pharma | 6-Amino-9-benzyl-8-hydroxy-purine derivatives and interferon inducers, antiviral agents, anticancer agents and therapeutic agents for immunologic diseases thereof |
| EA200000683A1 (ru) | 1998-01-19 | 2000-12-25 | Пфайзер Инк. | Производные ряда 4-(2-кето-1-бензимидазолинил)пиперидина в качестве агонистов orl1-рецептора |
| CN1166665C (zh) | 1998-03-19 | 2004-09-15 | 日本农药株式会社 | 芳基哌啶衍生物及其用途 |
| WO1999051608A1 (en) | 1998-04-03 | 1999-10-14 | Du Pont Pharmaceuticals Company | THIAZOLO[4,5-d]PYRIMIDINES AND PYRIDINES AS CORTICOTROPIN RELEASING FACTOR (CRF) ANTAGONISTS |
| MA26659A1 (fr) | 1998-08-06 | 2004-12-20 | Pfizer | Dérivés de benzimidazole nouveaux, compositions pharmaceutiques les contenant et procédé pour leur préparation. |
| SE9802729D0 (sv) | 1998-08-13 | 1998-08-13 | Astra Pharma Prod | Novel Compounds |
| US5988695A (en) | 1998-08-26 | 1999-11-23 | S&B Technical Products, Inc. | Pipe gasket with embedded ring |
| PE20001420A1 (es) | 1998-12-23 | 2000-12-18 | Pfizer | Moduladores de ccr5 |
| ES2229803T3 (es) | 1998-12-28 | 2005-04-16 | 4 Aza Bioscience Nv | Efectos inmunosupresivos de derivados de pteridina. |
| GB9900334D0 (en) | 1999-01-07 | 1999-02-24 | Angiogene Pharm Ltd | Tricylic vascular damaging agents |
| GB9900752D0 (en) | 1999-01-15 | 1999-03-03 | Angiogene Pharm Ltd | Benzimidazole vascular damaging agents |
| CA2361561A1 (en) | 1999-02-02 | 2000-08-10 | K.U. Leuven Research & Development | Immunosurpressive effects of pteridine derivatives |
| US6248755B1 (en) | 1999-04-06 | 2001-06-19 | Merck & Co., Inc. | Pyrrolidine modulators of chemokine receptor activity |
| US6142484A (en) | 1999-04-15 | 2000-11-07 | Vassallo Research & Development Corporation | Composite multi-pressure gasket |
| AU5600100A (en) | 1999-06-11 | 2001-01-02 | Merck & Co., Inc. | Cyclopentyl modulators of chemokine receptor activity |
| US6340681B1 (en) | 1999-07-16 | 2002-01-22 | Pfizer Inc | 2-benzimidazolylamine compounds as ORL-1-receptor agonists |
| EP1409487A1 (en) | 1999-09-15 | 2004-04-21 | Warner-Lambert Company Llc | Pteridinones as kinase inhibitors |
| SE9903544D0 (sv) | 1999-10-01 | 1999-10-01 | Astra Pharma Prod | Novel compounds |
| AR025884A1 (es) | 1999-10-01 | 2002-12-18 | Takeda Pharmaceutical | Compuestos de amina ciclica, su produccion y su uso |
| DE60023100T2 (de) | 2000-01-05 | 2006-07-06 | Pfizer Inc. | Benzimidazol-Verbindungen zur Verwendung als ORL1-Rezeptor-Antagonisten |
| GB2359081A (en) | 2000-02-11 | 2001-08-15 | Astrazeneca Uk Ltd | Pharmaceutically active thiazolopyrimidines |
| GB2359078A (en) | 2000-02-11 | 2001-08-15 | Astrazeneca Uk Ltd | Pharmaceutically active pyrimidine derivatives |
| GB2359079A (en) | 2000-02-11 | 2001-08-15 | Astrazeneca Uk Ltd | Pharmaceutically active pyrimidine derivatives |
| DE60101372T2 (de) | 2000-02-11 | 2004-10-14 | Astrazeneca Ab | Pyrimidinverbindungen und ihre verwendung als modulatoren der chemokin-rezeptor-aktivität |
| GB2359551A (en) | 2000-02-23 | 2001-08-29 | Astrazeneca Uk Ltd | Pharmaceutically active pyrimidine derivatives |
| GB0005642D0 (en) | 2000-03-10 | 2000-05-03 | Astrazeneca Uk Ltd | Chemical compounds |
| US6790854B2 (en) | 2000-03-24 | 2004-09-14 | Meiji Seika Kaisha, Ltd. | Diphenylalkylamine derivatives useful as opioid receptor agonists |
| NZ522074A (en) | 2000-05-31 | 2004-06-25 | Astrazeneca Ab | Indole derivatives with vascular damaging activity |
| CN1255392C (zh) | 2000-07-07 | 2006-05-10 | 安吉奥金尼药品有限公司 | 作为血管生成抑制剂的秋水仙醇衍生物 |
| IL153484A0 (en) | 2000-07-07 | 2003-07-06 | Angiogene Pharm Ltd | Colchinol derivatives as angiogenesis inhibitors |
| SE0003828D0 (sv) | 2000-10-20 | 2000-10-20 | Astrazeneca Ab | Novel compounds |
| SE0004110L (sv) | 2000-11-10 | 2002-05-11 | Forsheda Ab | Tätningsring |
| SE0101322D0 (sv) * | 2001-04-12 | 2001-04-12 | Astrazeneca Ab | Novel compounds |
| SE0102716D0 (sv) | 2001-08-14 | 2001-08-14 | Astrazeneca Ab | Novel compounds |
| GB0221828D0 (en) | 2002-09-20 | 2002-10-30 | Astrazeneca Ab | Novel compound |
| GB0221829D0 (en) | 2002-09-20 | 2002-10-30 | Astrazeneca Ab | Novel compound |
| CA2541533A1 (en) | 2003-10-07 | 2005-04-14 | Astrazeneca Ab | New 2-substituted, 4-amino-thiazolo[4,5-d] pyrimidines, useful as chemokine receptor antagonists, esp. cx3cr1 |
| GB0328243D0 (en) | 2003-12-05 | 2004-01-07 | Astrazeneca Ab | Methods |
| WO2005082865A1 (ja) | 2004-02-27 | 2005-09-09 | Astellas Pharma Inc. | 縮合二環性ピリミジン誘導体 |
| US20090239882A1 (en) | 2004-12-17 | 2009-09-24 | Astrazeneca Ab | Thiazolopyramidine Compounds for the Modulation of Chemokine Receptor Activity |
-
2003
- 2003-12-05 GB GBGB0328243.1A patent/GB0328243D0/en not_active Ceased
-
2004
- 2004-11-25 TW TW093136325A patent/TWI347945B/zh not_active IP Right Cessation
- 2004-12-02 CA CA002546719A patent/CA2546719A1/en not_active Abandoned
- 2004-12-02 MY MYPI20044990A patent/MY143761A/en unknown
- 2004-12-02 NZ NZ547685A patent/NZ547685A/en not_active IP Right Cessation
- 2004-12-02 WO PCT/GB2004/005072 patent/WO2005056563A2/en not_active Ceased
- 2004-12-02 DE DE602004027840T patent/DE602004027840D1/de not_active Expired - Lifetime
- 2004-12-02 AU AU2004296241A patent/AU2004296241B2/en not_active Ceased
- 2004-12-02 JP JP2006542009A patent/JP4808629B2/ja not_active Expired - Fee Related
- 2004-12-02 NZ NZ583012A patent/NZ583012A/en unknown
- 2004-12-02 AT AT04801262T patent/ATE471941T1/de not_active IP Right Cessation
- 2004-12-02 KR KR1020067010850A patent/KR101170188B1/ko not_active Expired - Fee Related
- 2004-12-02 ES ES04801262T patent/ES2345660T3/es not_active Expired - Lifetime
- 2004-12-02 US US10/581,143 patent/US7790883B2/en not_active Expired - Fee Related
- 2004-12-02 SG SG200809048-2A patent/SG149005A1/en unknown
- 2004-12-02 EP EP04801262A patent/EP1711505B1/en not_active Expired - Lifetime
- 2004-12-02 BR BRPI0417300-7A patent/BRPI0417300A/pt not_active IP Right Cessation
- 2004-12-02 CN CN2004800414459A patent/CN1914213B/zh not_active Expired - Fee Related
- 2004-12-03 AR ARP040104522A patent/AR046750A1/es active IP Right Grant
- 2004-12-03 UY UY28651A patent/UY28651A1/es not_active Application Discontinuation
-
2006
- 2006-05-18 IL IL175743A patent/IL175743A/en not_active IP Right Cessation
- 2006-06-01 ZA ZA200604491A patent/ZA200604491B/en unknown
- 2006-07-04 NO NO20063111A patent/NO20063111L/no not_active Application Discontinuation
-
2008
- 2008-05-15 US US12/121,228 patent/US20090043097A1/en not_active Abandoned
-
2009
- 2009-12-15 US US12/638,415 patent/US20100217000A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20070282103A1 (en) | 2007-12-06 |
| UY28651A1 (es) | 2005-07-29 |
| NO20063111L (no) | 2006-09-05 |
| IL175743A0 (en) | 2006-09-05 |
| GB0328243D0 (en) | 2004-01-07 |
| DE602004027840D1 (de) | 2010-08-05 |
| ES2345660T3 (es) | 2010-09-29 |
| CA2546719A1 (en) | 2005-06-23 |
| KR101170188B1 (ko) | 2012-07-31 |
| AU2004296241B2 (en) | 2009-01-22 |
| SG149005A1 (en) | 2009-01-29 |
| MY143761A (en) | 2011-07-15 |
| US7790883B2 (en) | 2010-09-07 |
| WO2005056563A3 (en) | 2005-08-25 |
| US20090043097A1 (en) | 2009-02-12 |
| NZ583012A (en) | 2011-08-26 |
| EP1711505B1 (en) | 2010-06-23 |
| BRPI0417300A (pt) | 2007-03-06 |
| KR20060118525A (ko) | 2006-11-23 |
| ZA200604491B (en) | 2007-10-31 |
| US20100217000A1 (en) | 2010-08-26 |
| EP1711505A2 (en) | 2006-10-18 |
| TWI347945B (en) | 2011-09-01 |
| NZ547685A (en) | 2010-02-26 |
| WO2005056563A2 (en) | 2005-06-23 |
| AR046750A1 (es) | 2005-12-21 |
| TW200524945A (en) | 2005-08-01 |
| AU2004296241A1 (en) | 2005-06-23 |
| CN1914213A (zh) | 2007-02-14 |
| JP2007513131A (ja) | 2007-05-24 |
| CN1914213B (zh) | 2011-05-11 |
| JP4808629B2 (ja) | 2011-11-02 |
| IL175743A (en) | 2011-10-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |