ATE469899T1 - Spiropiperidinderivate - Google Patents
SpiropiperidinderivateInfo
- Publication number
- ATE469899T1 ATE469899T1 AT07847384T AT07847384T ATE469899T1 AT E469899 T1 ATE469899 T1 AT E469899T1 AT 07847384 T AT07847384 T AT 07847384T AT 07847384 T AT07847384 T AT 07847384T AT E469899 T1 ATE469899 T1 AT E469899T1
- Authority
- AT
- Austria
- Prior art keywords
- spiropiperidine derivatives
- spiropiperidine
- derivatives
- Prior art date
Links
- JUXAVSAMVBLDKO-UHFFFAOYSA-N 1-(1-azabicyclo[2.2.2]octan-3-yl)-3-[3-(1h-indol-3-yl)-1-oxo-1-spiro[1,2-dihydroindene-3,4'-piperidine]-1'-ylpropan-2-yl]urea Chemical class C1N(CC2)CCC2C1NC(=O)NC(C(=O)N1CCC2(C3=CC=CC=C3CC2)CC1)CC1=CNC2=CC=CC=C12 JUXAVSAMVBLDKO-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Reproductive Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06125645 | 2006-12-07 | ||
| PCT/EP2007/062857 WO2008068159A1 (en) | 2006-12-07 | 2007-11-27 | Spiro-piperidine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE469899T1 true ATE469899T1 (de) | 2010-06-15 |
Family
ID=39201604
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07847384T ATE469899T1 (de) | 2006-12-07 | 2007-11-27 | Spiropiperidinderivate |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US7432259B2 (de) |
| EP (1) | EP2099799B1 (de) |
| JP (1) | JP2010511654A (de) |
| KR (1) | KR101111022B1 (de) |
| CN (1) | CN101541797A (de) |
| AR (1) | AR064136A1 (de) |
| AT (1) | ATE469899T1 (de) |
| AU (1) | AU2007329066B2 (de) |
| BR (1) | BRPI0720246A2 (de) |
| CA (1) | CA2670671A1 (de) |
| CL (1) | CL2007003483A1 (de) |
| DE (1) | DE602007006989D1 (de) |
| ES (1) | ES2343286T3 (de) |
| IL (1) | IL198549A0 (de) |
| MX (1) | MX2009005507A (de) |
| NO (1) | NO20091766L (de) |
| PE (1) | PE20081489A1 (de) |
| RU (1) | RU2009119393A (de) |
| TW (1) | TW200843758A (de) |
| WO (1) | WO2008068159A1 (de) |
| ZA (1) | ZA200903175B (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE488519T1 (de) * | 2005-09-28 | 2010-12-15 | Hoffmann La Roche | Indol-3-ylcarbonylazaspiroderivate als vasopressinrezeptorantagonisten |
| AU2010209825A1 (en) * | 2009-01-30 | 2011-08-11 | F. Hoffmann-La Roche Ag | Piperidine derivatives as NK3 receptor antagonists |
| US8324250B2 (en) * | 2009-03-19 | 2012-12-04 | Hoffmann-La Roche Inc. | Piperidine derivatives as NK3 receptor antagonists |
| SG11201604915PA (en) * | 2013-12-19 | 2016-07-28 | Hoffmann La Roche | Spiro-oxazolones |
| JP7368357B2 (ja) * | 2017-09-05 | 2023-10-24 | ブラックソーン セラピューティクス インコーポレイテッド | バソプレシン受容体アンタゴニストならびにそれに関連する生成物および方法 |
| WO2020048826A1 (en) | 2018-09-03 | 2020-03-12 | Bayer Aktiengesellschaft | 5-substituted 1-oxa-3,9-diazaspiro[5.5]undecan-2-one compounds |
| WO2020048828A1 (en) | 2018-09-03 | 2020-03-12 | Bayer Pharma Aktiengesellschaft | 5-heteroaryl-3,9-diazaspiro[5.5]undecane compounds |
| WO2020048829A1 (en) | 2018-09-03 | 2020-03-12 | Bayer Aktiengesellschaft | 3,9-diazaspiro[5.5]undecane compounds |
| WO2020048831A1 (en) | 2018-09-03 | 2020-03-12 | Bayer Aktiengesellschaft | 5-aryl-3,9-diazaspiro[5.5]undecan-2-one compounds |
| WO2020048830A1 (en) | 2018-09-03 | 2020-03-12 | Bayer Aktiengesellschaft | 5-aryl-3,9-diazaspiro[5.5]undecan-2-one compounds |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CO5150201A1 (es) | 1998-09-07 | 2002-04-29 | Hoffmann La Roche | Derivados de piperidina |
| US6911448B2 (en) | 2000-05-12 | 2005-06-28 | Solvay Pharmaceuticals B.V. | Piperazine and piperidine compounds |
| AU2003301436A1 (en) | 2002-10-17 | 2004-05-04 | Amgen Inc. | Benzimidazole derivatives and their use as vanilloid receptor ligands |
| BRPI0417267A (pt) * | 2003-12-22 | 2007-04-17 | Pfizer | derivados de triazol como antagonistas de vasopressina |
| US7351706B2 (en) * | 2006-01-05 | 2008-04-01 | Hoffmann-La Roche Inc. | Indol-3-yl-carbonyl-spiro-piperidine derivatives |
-
2007
- 2007-11-27 BR BRPI0720246-6A patent/BRPI0720246A2/pt not_active IP Right Cessation
- 2007-11-27 CA CA002670671A patent/CA2670671A1/en not_active Abandoned
- 2007-11-27 CN CNA2007800432751A patent/CN101541797A/zh active Pending
- 2007-11-27 AU AU2007329066A patent/AU2007329066B2/en not_active Ceased
- 2007-11-27 JP JP2009539698A patent/JP2010511654A/ja not_active Ceased
- 2007-11-27 AT AT07847384T patent/ATE469899T1/de active
- 2007-11-27 MX MX2009005507A patent/MX2009005507A/es active IP Right Grant
- 2007-11-27 RU RU2009119393/04A patent/RU2009119393A/ru not_active Application Discontinuation
- 2007-11-27 WO PCT/EP2007/062857 patent/WO2008068159A1/en not_active Ceased
- 2007-11-27 DE DE602007006989T patent/DE602007006989D1/de active Active
- 2007-11-27 KR KR1020097011663A patent/KR101111022B1/ko not_active Expired - Fee Related
- 2007-11-27 ES ES07847384T patent/ES2343286T3/es active Active
- 2007-11-27 EP EP07847384A patent/EP2099799B1/de not_active Not-in-force
- 2007-11-30 US US11/947,822 patent/US7432259B2/en not_active Expired - Fee Related
- 2007-11-30 US US11/947,836 patent/US8022213B2/en not_active Expired - Fee Related
- 2007-12-04 TW TW096146110A patent/TW200843758A/zh unknown
- 2007-12-04 CL CL200703483A patent/CL2007003483A1/es unknown
- 2007-12-05 AR ARP070105427A patent/AR064136A1/es unknown
- 2007-12-06 PE PE2007001737A patent/PE20081489A1/es not_active Application Discontinuation
-
2009
- 2009-05-04 IL IL198549A patent/IL198549A0/en unknown
- 2009-05-05 NO NO20091766A patent/NO20091766L/no not_active Application Discontinuation
- 2009-05-07 ZA ZA200903175A patent/ZA200903175B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200903175B (en) | 2010-03-31 |
| US8022213B2 (en) | 2011-09-20 |
| CN101541797A (zh) | 2009-09-23 |
| CA2670671A1 (en) | 2008-06-12 |
| US7432259B2 (en) | 2008-10-07 |
| CL2007003483A1 (es) | 2008-07-04 |
| KR20090080112A (ko) | 2009-07-23 |
| IL198549A0 (en) | 2010-02-17 |
| EP2099799A1 (de) | 2009-09-16 |
| EP2099799B1 (de) | 2010-06-02 |
| DE602007006989D1 (en) | 2010-07-15 |
| ES2343286T3 (es) | 2010-07-27 |
| RU2009119393A (ru) | 2011-01-20 |
| JP2010511654A (ja) | 2010-04-15 |
| AU2007329066B2 (en) | 2012-04-12 |
| AU2007329066A1 (en) | 2008-06-12 |
| AR064136A1 (es) | 2009-03-18 |
| BRPI0720246A2 (pt) | 2013-12-31 |
| US20080161299A1 (en) | 2008-07-03 |
| TW200843758A (en) | 2008-11-16 |
| NO20091766L (no) | 2009-07-06 |
| MX2009005507A (es) | 2009-06-03 |
| PE20081489A1 (es) | 2008-10-30 |
| WO2008068159A1 (en) | 2008-06-12 |
| KR101111022B1 (ko) | 2012-03-14 |
| US20080161298A1 (en) | 2008-07-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE475662T1 (de) | Dihydropyrazolopyrimidinonderivate | |
| ATE483711T1 (de) | Spiroindolinonderivate | |
| ATE469905T1 (de) | Pyridopyrimidinonderivate | |
| ATE512135T1 (de) | Spiroindolinonderivate | |
| DK2035394T3 (da) | 2-pyrazincarboxamidderivater | |
| DK2164844T3 (da) | Pyrimidinyl-pyridazinonderivater | |
| DK2209786T3 (da) | Pyrimidinsubstituerede purinderivater | |
| BRPI0820112A2 (pt) | Derivados de isoxazol-piridina | |
| BRPI0809992A2 (pt) | Derivados de pirrolopirimidina | |
| BRPI0820113A2 (pt) | Derivados de isoxazolo-piridazina | |
| DK2125827T3 (da) | Azaspiroderivater | |
| BRPI0813836A2 (pt) | Derivados pirazólicos | |
| BRPI0812155A2 (pt) | derivados de espiroindolinona | |
| BRPI0817935A2 (pt) | Derivados de biarila | |
| AT504580A3 (de) | Scan-einrichtung | |
| BRPI0814236A2 (pt) | Derivados de quinazolinamida | |
| ATE518837T1 (de) | Indazolamidderivate | |
| BRPI0820649A2 (pt) | Derivados de isoxazalo-pirazina | |
| DK2152370T3 (da) | Aryletherpyridazinonderivater | |
| BRPI0717939A2 (pt) | Aminometil-4-imidazóis | |
| ATE536356T1 (de) | Spiropiperidin-glycinamid-derivate | |
| ATE544764T1 (de) | 5-hydroxymethyloxazolidin-2-onderivate | |
| DE602007007460D1 (de) | Sehkrafttestsystem | |
| DE602007001593D1 (de) | Aryl-/alkylvinylsulfon-hyaluronsäurederivate | |
| ATE519760T1 (de) | Isoxazolimidazolderivate |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 2099799 Country of ref document: EP |