DE602007006989D1 - Spiropiperidinderivate - Google Patents
SpiropiperidinderivateInfo
- Publication number
- DE602007006989D1 DE602007006989D1 DE602007006989T DE602007006989T DE602007006989D1 DE 602007006989 D1 DE602007006989 D1 DE 602007006989D1 DE 602007006989 T DE602007006989 T DE 602007006989T DE 602007006989 T DE602007006989 T DE 602007006989T DE 602007006989 D1 DE602007006989 D1 DE 602007006989D1
- Authority
- DE
- Germany
- Prior art keywords
- spiropiperidinderivate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/10—Spiro-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06125645 | 2006-12-07 | ||
PCT/EP2007/062857 WO2008068159A1 (en) | 2006-12-07 | 2007-11-27 | Spiro-piperidine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602007006989D1 true DE602007006989D1 (en) | 2010-07-15 |
Family
ID=39201604
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602007006989T Active DE602007006989D1 (en) | 2006-12-07 | 2007-11-27 | Spiropiperidinderivate |
Country Status (21)
Country | Link |
---|---|
US (2) | US8022213B2 (de) |
EP (1) | EP2099799B1 (de) |
JP (1) | JP2010511654A (de) |
KR (1) | KR101111022B1 (de) |
CN (1) | CN101541797A (de) |
AR (1) | AR064136A1 (de) |
AT (1) | ATE469899T1 (de) |
AU (1) | AU2007329066B2 (de) |
BR (1) | BRPI0720246A2 (de) |
CA (1) | CA2670671A1 (de) |
CL (1) | CL2007003483A1 (de) |
DE (1) | DE602007006989D1 (de) |
ES (1) | ES2343286T3 (de) |
IL (1) | IL198549A0 (de) |
MX (1) | MX2009005507A (de) |
NO (1) | NO20091766L (de) |
PE (1) | PE20081489A1 (de) |
RU (1) | RU2009119393A (de) |
TW (1) | TW200843758A (de) |
WO (1) | WO2008068159A1 (de) |
ZA (1) | ZA200903175B (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE488519T1 (de) * | 2005-09-28 | 2010-12-15 | Hoffmann La Roche | Indol-3-ylcarbonylazaspiroderivate als vasopressinrezeptorantagonisten |
WO2010086259A1 (en) * | 2009-01-30 | 2010-08-05 | F. Hoffmann-La Roche Ag | Piperidine derivatives as nk3 receptor antagonists |
US8324250B2 (en) * | 2009-03-19 | 2012-12-04 | Hoffmann-La Roche Inc. | Piperidine derivatives as NK3 receptor antagonists |
WO2015091411A1 (en) * | 2013-12-19 | 2015-06-25 | F. Hoffmann-La Roche Ag | Spiro-oxazolones |
EP3679043B9 (de) * | 2017-09-05 | 2023-09-27 | Neumora Therapeutics, Inc. | Vasopressin-rezeptor-antagonisten und damit verbundene produkte und verfahren |
WO2020048830A1 (en) | 2018-09-03 | 2020-03-12 | Bayer Aktiengesellschaft | 5-aryl-3,9-diazaspiro[5.5]undecan-2-one compounds |
WO2020048831A1 (en) | 2018-09-03 | 2020-03-12 | Bayer Aktiengesellschaft | 5-aryl-3,9-diazaspiro[5.5]undecan-2-one compounds |
WO2020048828A1 (en) | 2018-09-03 | 2020-03-12 | Bayer Pharma Aktiengesellschaft | 5-heteroaryl-3,9-diazaspiro[5.5]undecane compounds |
AR116020A1 (es) | 2018-09-03 | 2021-03-25 | Bayer Ag | COMPUESTOS DE 3,9-DIAZAESPIRO[5.5]UNDECANO COMO INHIBIDORES DE GGTasa I Y SU USO PARA EL TRATAMIENTO DE ENFERMEDADES HIPERPROLIFERATIVAS |
WO2020048826A1 (en) | 2018-09-03 | 2020-03-12 | Bayer Aktiengesellschaft | 5-substituted 1-oxa-3,9-diazaspiro[5.5]undecan-2-one compounds |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CO5150201A1 (es) | 1998-09-07 | 2002-04-29 | Hoffmann La Roche | Derivados de piperidina |
HUP0302016A2 (hu) | 2000-05-12 | 2003-09-29 | Solvay Pharmaceuticals B.V. | Piperazin és piperidinvegyületek, ezeket tartalmazó gyógyászati készítmények, eljárás elżállításukra és alkalmazásuk |
MXPA05003948A (es) | 2002-10-17 | 2005-06-17 | Amgen Inc | Derivados de bencimidazol y su uso como ligandos de receptor vaniloide. |
GEP20084571B (en) * | 2003-12-22 | 2008-12-25 | Pfizer | Triazole derivatives as vasopressin antagonists |
US7351706B2 (en) * | 2006-01-05 | 2008-04-01 | Hoffmann-La Roche Inc. | Indol-3-yl-carbonyl-spiro-piperidine derivatives |
-
2007
- 2007-11-27 CA CA002670671A patent/CA2670671A1/en not_active Abandoned
- 2007-11-27 ES ES07847384T patent/ES2343286T3/es active Active
- 2007-11-27 AU AU2007329066A patent/AU2007329066B2/en not_active Ceased
- 2007-11-27 KR KR1020097011663A patent/KR101111022B1/ko not_active IP Right Cessation
- 2007-11-27 DE DE602007006989T patent/DE602007006989D1/de active Active
- 2007-11-27 WO PCT/EP2007/062857 patent/WO2008068159A1/en active Application Filing
- 2007-11-27 CN CNA2007800432751A patent/CN101541797A/zh active Pending
- 2007-11-27 BR BRPI0720246-6A patent/BRPI0720246A2/pt not_active IP Right Cessation
- 2007-11-27 RU RU2009119393/04A patent/RU2009119393A/ru not_active Application Discontinuation
- 2007-11-27 EP EP07847384A patent/EP2099799B1/de not_active Not-in-force
- 2007-11-27 MX MX2009005507A patent/MX2009005507A/es active IP Right Grant
- 2007-11-27 JP JP2009539698A patent/JP2010511654A/ja not_active Ceased
- 2007-11-27 AT AT07847384T patent/ATE469899T1/de active
- 2007-11-30 US US11/947,836 patent/US8022213B2/en not_active Expired - Fee Related
- 2007-11-30 US US11/947,822 patent/US7432259B2/en not_active Expired - Fee Related
- 2007-12-04 TW TW096146110A patent/TW200843758A/zh unknown
- 2007-12-04 CL CL200703483A patent/CL2007003483A1/es unknown
- 2007-12-05 AR ARP070105427A patent/AR064136A1/es unknown
- 2007-12-06 PE PE2007001737A patent/PE20081489A1/es not_active Application Discontinuation
-
2009
- 2009-05-04 IL IL198549A patent/IL198549A0/en unknown
- 2009-05-05 NO NO20091766A patent/NO20091766L/no not_active Application Discontinuation
- 2009-05-07 ZA ZA200903175A patent/ZA200903175B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
US7432259B2 (en) | 2008-10-07 |
CA2670671A1 (en) | 2008-06-12 |
ZA200903175B (en) | 2010-03-31 |
ATE469899T1 (de) | 2010-06-15 |
KR101111022B1 (ko) | 2012-03-14 |
KR20090080112A (ko) | 2009-07-23 |
EP2099799A1 (de) | 2009-09-16 |
US8022213B2 (en) | 2011-09-20 |
ES2343286T3 (es) | 2010-07-27 |
WO2008068159A1 (en) | 2008-06-12 |
JP2010511654A (ja) | 2010-04-15 |
AU2007329066A1 (en) | 2008-06-12 |
CL2007003483A1 (es) | 2008-07-04 |
IL198549A0 (en) | 2010-02-17 |
US20080161299A1 (en) | 2008-07-03 |
AR064136A1 (es) | 2009-03-18 |
TW200843758A (en) | 2008-11-16 |
NO20091766L (no) | 2009-07-06 |
RU2009119393A (ru) | 2011-01-20 |
EP2099799B1 (de) | 2010-06-02 |
MX2009005507A (es) | 2009-06-03 |
US20080161298A1 (en) | 2008-07-03 |
BRPI0720246A2 (pt) | 2013-12-31 |
PE20081489A1 (es) | 2008-10-30 |
AU2007329066B2 (en) | 2012-04-12 |
CN101541797A (zh) | 2009-09-23 |
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