ATE466932T1 - Vermehrung von viren in zellkultur - Google Patents
Vermehrung von viren in zellkulturInfo
- Publication number
- ATE466932T1 ATE466932T1 AT02777068T AT02777068T ATE466932T1 AT E466932 T1 ATE466932 T1 AT E466932T1 AT 02777068 T AT02777068 T AT 02777068T AT 02777068 T AT02777068 T AT 02777068T AT E466932 T1 ATE466932 T1 AT E466932T1
- Authority
- AT
- Austria
- Prior art keywords
- viruses
- cell culture
- cells
- multiplication
- reproduction
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12051—Methods of production or purification of viral material
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Communicable Diseases (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10144903A DE10144903A1 (de) | 2001-09-12 | 2001-09-12 | Vermehrung von Viren in Zellkultur |
| PCT/EP2002/010207 WO2003023025A1 (de) | 2001-09-12 | 2002-09-11 | Vermehrung von viren in zellkultur |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE466932T1 true ATE466932T1 (de) | 2010-05-15 |
Family
ID=7698761
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02777068T ATE466932T1 (de) | 2001-09-12 | 2002-09-11 | Vermehrung von viren in zellkultur |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20050118698A1 (https=) |
| EP (1) | EP1427817B1 (https=) |
| JP (2) | JP2005502357A (https=) |
| KR (1) | KR100968141B1 (https=) |
| AT (1) | ATE466932T1 (https=) |
| AU (1) | AU2002338666B2 (https=) |
| BR (1) | BR0212469A (https=) |
| CA (1) | CA2456561A1 (https=) |
| CY (1) | CY1110716T1 (https=) |
| DE (2) | DE10144903A1 (https=) |
| DK (1) | DK1427817T3 (https=) |
| ES (1) | ES2345606T3 (https=) |
| NZ (1) | NZ532203A (https=) |
| PT (1) | PT1427817E (https=) |
| SI (1) | SI1427817T1 (https=) |
| WO (1) | WO2003023025A1 (https=) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ551640A (en) * | 2004-05-20 | 2010-05-28 | Id Biomedical Corp | Process for the production of an influenza vaccine |
| JP2008512443A (ja) | 2004-09-09 | 2008-04-24 | カイロン ベーリング ゲーエムベーハー アンド カンパニー | インフルエンザワクチンに関連する潜在的医原性リスクの減少 |
| CA2627971A1 (en) | 2005-11-01 | 2007-05-10 | Novartis Vaccines And Diagnostics Gmbh & Co Kg. | Cell-derived viral vaccines with low levels of residual cell dna by beta-propiolactone treatment |
| US20090304742A1 (en) | 2005-11-04 | 2009-12-10 | Novartis Vaccines And Diagnostics Srl | Influenza vaccines with reduced amount of emulsion adjuvant |
| WO2007052061A2 (en) | 2005-11-04 | 2007-05-10 | Novartis Vaccines And Diagnostics Srl | Emulsions with free aqueous-phase surfactant as adjuvants for split influenza vaccines |
| ES2420829T3 (es) | 2005-11-04 | 2013-08-27 | Novartis Vaccines And Diagnostics S.R.L. | Vacunas adyuvantadas con antígeno de no virión preparadas a partir de virus de la gripe cultivados en cultivo celular |
| EP1951298A1 (en) | 2005-11-04 | 2008-08-06 | Novartis Vaccines and Diagnostics S.r.l. | Adjuvanted influenza vaccines including cytokine-inducing agents |
| NZ568211A (en) | 2005-11-04 | 2011-11-25 | Novartis Vaccines & Diagnostic | Influenza vaccines including combinations of particulate adjuvants and immunopotentiators |
| EP2004226A1 (en) | 2006-03-24 | 2008-12-24 | Novartis Vaccines and Diagnostics GmbH & Co. KG | Storage of influenza vaccines without refrigeration |
| GB0614460D0 (en) | 2006-07-20 | 2006-08-30 | Novartis Ag | Vaccines |
| ES2536401T3 (es) * | 2006-09-11 | 2015-05-25 | Novartis Ag | Fabricación de vacunas contra virus de la gripe sin usar huevos |
| WO2008105931A2 (en) | 2006-09-15 | 2008-09-04 | Medimmune Vaccines, Inc. | Mdck cell lines supporting viral growth to high titers and bioreactor process using the same |
| EA201070066A1 (ru) | 2007-06-27 | 2010-06-30 | Новартис Аг | Вакцины против гриппа с низким содержанием добавок |
| GB0810305D0 (en) | 2008-06-05 | 2008-07-09 | Novartis Ag | Influenza vaccination |
| CN102215865B (zh) | 2008-09-24 | 2013-10-30 | 米迪缪尼有限公司 | 病毒纯化方法 |
| RU2547587C2 (ru) | 2008-09-24 | 2015-04-10 | Медиммун, Ллк | Способы культивирования клеток, размножения и очистки вирусов |
| JP2012507272A (ja) | 2008-11-05 | 2012-03-29 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 新規な方法 |
| FR2949344A1 (fr) | 2009-04-27 | 2011-03-04 | Novartis Ag | Vaccins de protection contre la grippe |
| CN102741399A (zh) * | 2009-10-20 | 2012-10-17 | 诺华有限公司 | 用于病毒拯救的改良反向遗传方法 |
| US9644187B2 (en) | 2010-04-14 | 2017-05-09 | Emd Millipore Corporation | Methods of producing high titer, high purity virus stocks and methods of use thereof |
| WO2011138682A2 (en) | 2010-05-06 | 2011-11-10 | Novartis Ag | Organic peroxide compounds for microorganism inactivation |
| AU2011254204B2 (en) | 2010-05-21 | 2015-08-20 | Seqirus UK Limited | Influenza virus reassortment method |
| CA2801151A1 (en) | 2010-06-01 | 2011-12-08 | Novartis Ag | Concentration of vaccine antigens with lyophilization |
| EP2575872B1 (en) | 2010-06-01 | 2020-08-19 | Seqirus UK Limited | Concentration of influenza vaccine antigens without lyophilization |
| ES2531577T3 (es) | 2010-08-20 | 2015-03-17 | Novartis Ag | Conjuntos de agujas para la administración de vacuna soluble contra la gripe |
| PH12013501708B1 (en) * | 2011-02-17 | 2018-08-03 | Boehringer Ingelheim Vetmedica Gmbh | Commercial scale process for production of prrsv |
| CA2829774C (en) | 2011-03-14 | 2019-09-24 | National Research Council Of Canada | Method of viral production in cells |
| GB201216121D0 (en) | 2012-09-10 | 2012-10-24 | Novartis Ag | Sample quantification by disc centrifugation |
| RU2599496C2 (ru) | 2012-03-06 | 2016-10-10 | Круселл Холланд Б.В. | Улучшенная вакцинация против гриппа |
| AU2013306080B2 (en) * | 2012-08-24 | 2019-01-31 | Global Life Sciences Solutions Usa Llc | Virus purification and formulation process |
| KR101370512B1 (ko) | 2013-06-07 | 2014-03-06 | 재단법인 목암생명공학연구소 | 무단백 배지에서 부유 배양되는 mdck 유래 세포주 및 상기 세포주를 이용하여 바이러스를 증식시키는 방법 |
| HK1254344A1 (zh) | 2015-06-26 | 2019-07-19 | Seqirus UK Limited | 抗原匹配的流感疫苗 |
| HUE051783T2 (hu) | 2015-07-07 | 2021-03-29 | Seqirus Uk Ltd | Eljárás immunogén hemagglutinin mennyiségi meghatározására |
| CN105561317B (zh) * | 2015-12-22 | 2018-03-20 | 肇庆大华农生物药品有限公司 | 重组伪狂犬病病毒疫苗耐热冻干保护剂及其制备方法 |
| CN108239619A (zh) * | 2016-12-23 | 2018-07-03 | 甘肃健顺生物科技有限公司 | 悬浮mdck细胞相关疫苗生产的二阶培养工艺技术 |
| CN108570445A (zh) * | 2017-11-09 | 2018-09-25 | 甘肃健顺生物科技有限公司 | Pk15细胞驯化悬浮方法和二阶病毒生产工艺 |
| CN108570444A (zh) * | 2017-11-09 | 2018-09-25 | 甘肃健顺生物科技有限公司 | St细胞驯化悬浮方法和二阶病毒生产工艺 |
| CN108570454A (zh) * | 2017-11-09 | 2018-09-25 | 甘肃健顺生物科技有限公司 | Mdbk驯化悬浮方法和二阶病毒生产工艺 |
| JP2023502650A (ja) | 2019-11-18 | 2023-01-25 | セキラス ピーティーワイ リミテッド | 遺伝子再集合インフルエンザウイルスを産生するための方法 |
| KR102444684B1 (ko) * | 2020-04-29 | 2022-09-16 | 에스케이바이오사이언스(주) | 일회용 배양 공정 시스템을 이용한 인플루엔자 바이러스 생산 방법 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19612966B4 (de) * | 1996-04-01 | 2009-12-10 | Novartis Vaccines And Diagnostics Gmbh & Co. Kg | MDCK-Zellen und Verfahren zur Vermehrung von Influenzaviren |
| ID20581A (id) * | 1996-10-18 | 1999-01-21 | Res Fnd For Micbial Diseases O | Antigen rotavirus, vaksin dan agen diagnostik untuk infeksi rotavirus, serta metode untuk menghasilkan antigen |
| GB9915413D0 (en) * | 1999-07-01 | 1999-09-01 | Glaxo Group Ltd | Propagation method |
| JP4698112B2 (ja) * | 2000-03-03 | 2011-06-08 | 一般財団法人化学及血清療法研究所 | 無血清培養かつ浮遊培養可能な細胞及び当該細胞を用いたワクチン用ウイルスの製造法 |
-
2001
- 2001-09-12 DE DE10144903A patent/DE10144903A1/de not_active Ceased
-
2002
- 2002-09-11 CA CA002456561A patent/CA2456561A1/en not_active Abandoned
- 2002-09-11 ES ES02777068T patent/ES2345606T3/es not_active Expired - Lifetime
- 2002-09-11 AU AU2002338666A patent/AU2002338666B2/en not_active Ceased
- 2002-09-11 PT PT02777068T patent/PT1427817E/pt unknown
- 2002-09-11 US US10/487,709 patent/US20050118698A1/en not_active Abandoned
- 2002-09-11 WO PCT/EP2002/010207 patent/WO2003023025A1/de not_active Ceased
- 2002-09-11 NZ NZ532203A patent/NZ532203A/en not_active IP Right Cessation
- 2002-09-11 JP JP2003527090A patent/JP2005502357A/ja active Pending
- 2002-09-11 BR BR0212469-6A patent/BR0212469A/pt not_active IP Right Cessation
- 2002-09-11 SI SI200230909T patent/SI1427817T1/sl unknown
- 2002-09-11 KR KR1020047003711A patent/KR100968141B1/ko not_active Expired - Lifetime
- 2002-09-11 DK DK02777068.4T patent/DK1427817T3/da active
- 2002-09-11 DE DE50214416T patent/DE50214416D1/de not_active Expired - Lifetime
- 2002-09-11 AT AT02777068T patent/ATE466932T1/de active
- 2002-09-11 EP EP02777068A patent/EP1427817B1/de not_active Expired - Lifetime
-
2010
- 2010-06-25 JP JP2010145663A patent/JP2010246559A/ja active Pending
- 2010-07-30 CY CY20101100718T patent/CY1110716T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ532203A (en) | 2005-04-29 |
| US20050118698A1 (en) | 2005-06-02 |
| HK1062029A1 (zh) | 2004-10-15 |
| PT1427817E (pt) | 2010-08-10 |
| EP1427817A1 (de) | 2004-06-16 |
| ES2345606T3 (es) | 2010-09-28 |
| DE50214416D1 (de) | 2010-06-17 |
| SI1427817T1 (sl) | 2010-08-31 |
| JP2010246559A (ja) | 2010-11-04 |
| DE10144903A1 (de) | 2003-03-27 |
| CA2456561A1 (en) | 2003-03-20 |
| CY1110716T1 (el) | 2015-06-10 |
| AU2002338666B2 (en) | 2008-11-20 |
| WO2003023025A1 (de) | 2003-03-20 |
| BR0212469A (pt) | 2004-08-24 |
| KR20050027164A (ko) | 2005-03-17 |
| EP1427817B1 (de) | 2010-05-05 |
| JP2005502357A (ja) | 2005-01-27 |
| DK1427817T3 (da) | 2010-08-23 |
| KR100968141B1 (ko) | 2010-07-06 |
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