ATE466858T1 - 3-arylisoxazol-4-carbonylbenzofuranderivative - Google Patents

3-arylisoxazol-4-carbonylbenzofuranderivative

Info

Publication number
ATE466858T1
ATE466858T1 AT06819173T AT06819173T ATE466858T1 AT E466858 T1 ATE466858 T1 AT E466858T1 AT 06819173 T AT06819173 T AT 06819173T AT 06819173 T AT06819173 T AT 06819173T AT E466858 T1 ATE466858 T1 AT E466858T1
Authority
AT
Austria
Prior art keywords
sup
derivatives
carbonylbenzofuran
arylisoxazole
cognitive
Prior art date
Application number
AT06819173T
Other languages
English (en)
Inventor
Bernd Buettelmann
Bo Han
Henner Knust
Matthias Nettekoven
Andrew Thomas
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE466858T1 publication Critical patent/ATE466858T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Furan Compounds (AREA)
AT06819173T 2005-11-09 2006-10-27 3-arylisoxazol-4-carbonylbenzofuranderivative ATE466858T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05110503 2005-11-09
PCT/EP2006/067879 WO2007054444A2 (en) 2005-11-09 2006-10-27 3-aryl-isoxazole-4-carbonyl-benzofuran derivatives

Publications (1)

Publication Number Publication Date
ATE466858T1 true ATE466858T1 (de) 2010-05-15

Family

ID=37876981

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06819173T ATE466858T1 (de) 2005-11-09 2006-10-27 3-arylisoxazol-4-carbonylbenzofuranderivative

Country Status (13)

Country Link
US (1) US7388025B2 (de)
EP (1) EP1948648B1 (de)
JP (1) JP2009514924A (de)
KR (1) KR101103129B1 (de)
CN (1) CN101304994B (de)
AT (1) ATE466858T1 (de)
AU (1) AU2006311092B2 (de)
BR (1) BRPI0618383A2 (de)
CA (1) CA2628667A1 (de)
DE (1) DE602006014185D1 (de)
ES (1) ES2341131T3 (de)
IL (1) IL190867A0 (de)
WO (1) WO2007054444A2 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100828891B1 (ko) * 2006-02-23 2008-05-09 엘지이노텍 주식회사 Led 패키지
MX2014003488A (es) 2011-09-26 2014-07-22 Koninkl Philips Nv Sistema de formacion de imagenes de gantry giratorio y control de movimiento de soporte del objetivo.
CA2862095C (en) 2012-02-01 2017-04-11 Basf Se Process for the manufacture of paper and paperboard
US20150374705A1 (en) 2012-02-14 2015-12-31 Shanghai Institues for Biological Sciences Substances for treatment or relief of pain
ES2663384T5 (es) 2012-03-01 2024-10-18 Basf Se Proceso para la fabricación de papel y cartón
BR112014032501A2 (pt) 2012-06-26 2017-06-27 Saniona Aps composto, e, composição farmacêutica.
WO2014001279A1 (en) 2012-06-26 2014-01-03 Aniona Aps A phenyl triazole derivative and its use for modulating the gabaa receptor complex
WO2014001280A1 (en) 2012-06-26 2014-01-03 Aniona Aps A phenyl triazole derivative and its use for modulating the gabaa receptor complex
AU2013283487C1 (en) 2012-06-26 2018-01-18 Saniona Aps A phenyl triazole derivative and its use for modulating the GABAA receptor complex
WO2014001278A1 (en) 2012-06-26 2014-01-03 Aniona Aps A phenyl triazole derivative and its use for modulating the gabaa receptor complex
ES2873105T3 (es) 2013-01-11 2021-11-03 Solenis Technologies Cayman Lp Proceso para la fabricación de papel y cartón
BR102019014802A2 (pt) 2018-07-20 2020-02-04 Boehringer Ingelheim Int difluorometil-fenil triazóis
EP4126858A1 (de) * 2020-03-26 2023-02-08 Richter Gedeon Nyrt. Dihydro-2-pyrrolo[3,4-c pyridin-derivate als gabaa a5 rezeptormodulatoren
IL296716A (en) * 2020-03-26 2022-11-01 Richter Gedeon Nyrt History of naphthyridine and pyrido[4,3-c]pyridazine as gabaa alpha 5 receptor modulators

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1314191B1 (it) 1999-10-18 2002-12-06 Recordati Chem Pharm Derivati isossazolcarbossamidici
KR20040027870A (ko) 2001-07-05 2004-04-01 시냅틱 파마세틱칼 코포레이션 Mch 선택적인 안타고니스트로서의 치환 아닐린 피페리딘
JP2005501073A (ja) * 2001-08-06 2005-01-13 フアルマシア・イタリア・エツセ・ピー・アー キナーゼ阻害薬活性を有するアミノイソオキサゾール誘導体
GB0128160D0 (en) * 2001-11-23 2002-01-16 Merck Sharp & Dohme Novel compounds

Also Published As

Publication number Publication date
AU2006311092A1 (en) 2007-05-18
BRPI0618383A2 (pt) 2011-08-30
CN101304994B (zh) 2011-06-29
CN101304994A (zh) 2008-11-12
CA2628667A1 (en) 2007-05-18
KR101103129B1 (ko) 2012-01-04
DE602006014185D1 (de) 2010-06-17
US7388025B2 (en) 2008-06-17
WO2007054444A3 (en) 2007-06-28
EP1948648A2 (de) 2008-07-30
KR20080065697A (ko) 2008-07-14
WO2007054444A2 (en) 2007-05-18
AU2006311092B2 (en) 2011-05-12
IL190867A0 (en) 2008-11-03
ES2341131T3 (es) 2010-06-15
EP1948648B1 (de) 2010-05-05
JP2009514924A (ja) 2009-04-09
US20070105922A1 (en) 2007-05-10

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